Patents by Inventor Phillip A. Patten
Phillip A. Patten has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 10337026Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: March 13, 2018Date of Patent: July 2, 2019Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Ruth Cong, Jingtong Hou, Zhenglin Hou, Phillip A. Patten, Takashi Yamamoto
-
Patent number: 10316326Abstract: Compositions and methods comprising polynucleotides and polypeptides having 4-hydroxyphenylpyruvate dioxygenase (HPPD) activity and having insensitivity to an HPPD inhibitor are provided. Further provided are nucleic acid constructs, plants, plant cells, explants, seeds and grain having the HPPD sequences. Various methods of employing the HPPD sequences are provided. Such methods include, for example, methods for producing an HPPD inhibitor tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein. Methods are also provided to identify additional HPPD variants. Further provided are various methods and compositions that allow the various HPPD polypeptides and variant and fragments thereof to be expressed in a chloroplast or transported to a chloroplast.Type: GrantFiled: May 2, 2015Date of Patent: June 11, 2019Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Daniel Siehl, Phillip A. Patten, Yumin Tao, Ericka Bermudez, Linda A. Castle, Yuxia Dong, Andrew Duncan Satterfield, Henrik Albert
-
Patent number: 10294490Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: September 23, 2016Date of Patent: May 21, 2019Assignees: PIONEER HI-BRED INTERNATIONAL, INC., E I DU PONT NEMOURS AND COMPANYInventors: Daniel J Altier, Jennifer K Barry, Carol A Hendrick, Lu Liu, Phillip A Patten, Claudia D Perez-Ortega, Eric J Schepers, Weiping Xie, Nasser Yalpani, Jianzhou Zhao, Xiaohong Zhong, Genhai Zhu
-
Publication number: 20190024110Abstract: Compositions and methods comprising polynucleotides and polypeptides having EPSP (5-enolpyruvylshikimate-3-phosphate) synthase (EPSPS) activity are provided. In specific embodiments, the sequence has an improved property, such as, but not limited to, improved catalytic capacity in the presence of the inhibitor, glyphosate. Further provided are nucleic acid constructs, plants, plant cells, explants, seeds and grain having the EPSPS sequences. Various methods of employing the EPSPS sequences are provided. Such methods include methods for producing a glyphosate tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein.Type: ApplicationFiled: September 29, 2016Publication date: January 24, 2019Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: YUXIA DONG, MICHAEL LASSNER, JIAN LU, EMILY NG, PHILLIP A. PATTEN, DANIEL SIEHL
-
Publication number: 20180291398Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: June 20, 2018Publication date: October 11, 2018Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Ruth Cong, Jingtong Hou, Zhenglin Hou, Phillip A. Patten, Takashi Yamamoto
-
Publication number: 20180216132Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: March 13, 2018Publication date: August 2, 2018Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: RUTH CONG, JINGTONG HOU, ZHENGLIN HOU, PHILLIP A. PATTEN, TAKASHI YAMAMOTO
-
Patent number: 10023877Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: March 12, 2014Date of Patent: July 17, 2018Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Ruth Cong, Jingtong Hou, Zhenglin Hou, Phillip A. Patten, Takashi Yamamoto
-
Patent number: 9996661Abstract: The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods.Type: GrantFiled: December 28, 2010Date of Patent: June 12, 2018Assignee: Codexis Mayflower Holdings, LLCInventors: Claes Gustafsson, Sridhar Govindarajan, Robin A. Emig, Richard John Fox, Ajoy K. Roy, Jeremy S. Minshull, S. Christopher Davis, Anthony R. Cox, Phillip A. Patten, Linda A. Castle, Daniel L. Siehl, Rebecca Lynne Gorton, Teddy Chen
-
Patent number: 9951348Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: June 9, 2016Date of Patent: April 24, 2018Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Ruth Cong, Jingtong Hou, Zhenglin Hou, Phillip Patten, Takashi Yamamoto
-
Publication number: 20170348666Abstract: Provided herein are architectures and compositions of capture templates and macro capture templates, optionally attached to dendrimers, methods of using capture templates and/or macro capture templates, optionally attached to dendrimers to route coding templates, novel combinations including solid supports and capture templates and/or macro capture templates, optionally attached to dendrimers, methods of using novel combinations of solid supports and dendrimers and capture templates and/or macro capture templates to route coding templates, novel compositions which include capture templates and macro capture templates, optionally attached to dendrimers, hybridized to coding templates and novel compositions including solid supports, and capture templates and/or macro capture templates optionally attached to dendrimers hybridized to coding templates.Type: ApplicationFiled: June 5, 2017Publication date: December 7, 2017Inventors: Phillip Patten, Madan Paidhungat, Pehr Harbury, Robin Prince, Craig Skinner, Malathy Sridhar
-
Publication number: 20170327546Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: May 23, 2017Publication date: November 16, 2017Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: DAVID C. CERF, JAMES J. ENGLISH, CAROL A. HENDRICK, LU LIU, JARRED K. ORAL, PHILLIP A. PATTEN, BARBARA A. ROSEN, UTE SCHELLENBERGER, INGRID UDRANSZKY, JUN-ZHI WEI, GENHAI ZHU
-
Patent number: 9688730Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: March 11, 2013Date of Patent: June 27, 2017Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: David C. Cerf, James J. English, Carol A. Hendrick, Lu Liu, Jarred K. Oral, Phillip A. Patten, Barbara A. Rosen, Ute Schellenberger, Ingrid A. Udranszky, Jun-Zhi Wei, Genhai Zhu
-
Publication number: 20170153257Abstract: Disclosed herein are methods of estimating LogD of compounds comprising a ligand operatively linked to a recognition element. The methods generally involve contacting the compounds with a matrix, measuring the interaction of the compounds with the matrix and relating the interaction of the compounds with the matrix to LogD of the compounds. Also, described herein, are novel compounds which include a ligand operatively linked to a recognition element and linkers that connect the ligand to the recognition element.Type: ApplicationFiled: October 10, 2016Publication date: June 1, 2017Inventors: Phillip Patten, Pehr Harbury, Donald Schmidt, Martin Linsell, Kenneth Wlasichuk, Robin Prince, Timothy J. Church, Wouter Van der Linden
-
Patent number: 9617256Abstract: Antibacterial compounds of formula (I) are provided: as well as stereoisomers, pharmaceutically acceptable salts, esters, and prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.Type: GrantFiled: March 24, 2014Date of Patent: April 11, 2017Assignee: Achaogen, Inc.Inventors: Heinz E. Moser, Qing Lu, Phillip A. Patten, Dan Wang, Ramesh Kasar, Stephen Kaldor, Brian D. Patterson
-
Publication number: 20170088549Abstract: Antibacterial compounds of formula (I) are provided: as well as stereoisomers, pharmaceutically acceptable salts, esters, and prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.Type: ApplicationFiled: December 12, 2016Publication date: March 30, 2017Inventors: Heinz Ernst MOSER, Qing LU, Phillip A. PATTEN, Dan WANG, Ramesh Annasaheb KASAR, Stephen W. KALDOR, Brian D. PATTERSON
-
Publication number: 20170058291Abstract: Compositions and methods comprising polynucleotides and polypeptides having 4-hydroxyphenylpyruvate dioxygenase (HPPD) activity and having insensitivity to an HPPD inhibitor are provided. Further provided are nucleic acid constructs, plants, plant cells, explants, seeds and grain having the HPPD sequences. Various methods of employing the HPPD sequences are provided. Such methods include, for example, methods for producing an HPPD inhibitor tolerant plant, plant cell, explant or seed and methods of controlling weeds in a field containing a crop employing the plants and/or seeds disclosed herein. Methods are also provided to identify additional HPPD variants. Further provided are various methods and compositions that allow the various HPPD polypeptides and variant and fragments thereof to be expressed in a chloroplast or transported to a chloroplast.Type: ApplicationFiled: May 2, 2015Publication date: March 2, 2017Inventors: Daniel Siehl, Phillip A. Patten, Yumin Tao, Ericka Bermudez, Linda A. Castle, Yuxia Dong, Andrew Duncan Satterfield, Henrik Albert
-
Publication number: 20170006867Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: September 23, 2016Publication date: January 12, 2017Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: DANIEL J ALTIER, JENNIFER K BARRY, CAROL A HENDRICK, LU LIU, PHILLIP A PATTEN, CLAUDIA D PEREZ-ORTEGA, ERIC J SCHEPERS, WEIPING XIE, NASSAR YALPANI, JIANZHOU ZHAO, XIAOHONG ZHONG, GENHAI ZHU
-
Patent number: 9475847Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: March 13, 2013Date of Patent: October 25, 2016Assignees: PIONEER HI-BRED INTERNATIONAL, INC., E.I. DU PONT DE NEMOURS AND COMPANYInventors: Daniel J. Altier, Jennifer K. Barry, Carol A. Hendrick, Lu Liu, Phillip A. Patten, Claudia D. Perez-Ortega, Eric J. Schepers, Weiping Xie, Nasser Yalpani, Jianzhou Zhao, Xiaohong Zhong, Genhai Zhu
-
Publication number: 20160281105Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: June 9, 2016Publication date: September 29, 2016Applicant: PIONEER HI-BRED INTERANTIONAL, INC.Inventors: RUTH CONG, JINGTONG HOU, ZHENGLIN HOU, PHILLIP PATTEN, TAKASHI YAMAMOTO
-
Patent number: 9394345Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest, as probes for the isolation of other homologous (or partially homologous) genes. The insecticidal proteins find use in controlling, inhibiting growth or killing lepidopteran, coleopteran, dipteran, fungal, hemipteran, and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: March 15, 2013Date of Patent: July 19, 2016Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Ruth Cong, Jingtong Hou, Zhenglin Hou, Phillip Patten, Takashi Yamamoto