Patents by Inventor Phillip A. Patten

Phillip A. Patten has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Glyphosate-N-acetyltransferase (GAT) genes
    Patent number: 7863503
    Abstract: Novel proteins are provided herein, including proteins capable of catalyzing the acetylation of glyphosate and other structurally related proteins. Also provided are novel polynucleotides capable of encoding these proteins, compositions that include one or more of these novel proteins and/or polynucleotides, recombinant cells and transgenic plants comprising these novel compounds, diversification methods involving the novel compounds, and methods of using the compounds. Some of the novel methods and compounds provided herein can be used to render an organism, such as a plant, resistant to glyphosate.
    Type: Grant
    Filed: March 21, 2008
    Date of Patent: January 4, 2011
    Assignees: Pioneer Hi-Bred International, Inc., E.I. du Pont de Nemours and Co., Verdia, Inc.
    Inventors: Linda A. Castle, Dan Siehl, Lorraine Giver, Jeremy Minshull, Christina Ivy, Yong Hong Chen, Phillip A. Patten, Rebecca Gorton, Nicholas B. Duck, Billy Fred McCutchen, Roger Kemble
  • Method for making polynucleotides having desired characteristics
    Patent number: 7853410
    Abstract: In silico nucleic acid recombination methods, related integrated systems utilizing genetic operators and libraries made by in silico shuffling methods are provided.
    Type: Grant
    Filed: October 18, 2007
    Date of Patent: December 14, 2010
    Assignee: Codexis, Inc.
    Inventors: Sergey A. Selifonov, Willem P. C. Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip A. Patten, Jeremy Minshull, Lorraine J. Giver
  • Methods, systems, and software for identifying functional biomolecules
    Patent number: 7783428
    Abstract: The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods.
    Type: Grant
    Filed: March 3, 2003
    Date of Patent: August 24, 2010
    Assignee: Maxygen, Inc.
    Inventors: Claes Gustafsson, Sridhar Govindarajan, Robin A. Emig, Richard John Fox, Ajoy K. Roy, Jeremy S. Minshull, S. Christopher Davis, Anthony R. Cox, Phillip A. Patten, Linda A. Castle, Daniel L. Siehl, Rebecca Lynne Gorton, Teddy Chen
  • Methods and compositions for polypeptide engineering
    Patent number: 7776598
    Abstract: Methods are provided for the evolution of proteins of industrial and pharmaceutical interest, including methods for effecting recombination and selection. Compositions produced by these methods are also disclosed.
    Type: Grant
    Filed: February 5, 2008
    Date of Patent: August 17, 2010
    Assignee: Maxygen, Inc.
    Inventors: Phillip A. Patten, Willem P. C. Stemmer
  • NOVEL GLYPHOSATE-N-ACETYLTRANSFERASE (GAT) GENES
    Publication number: 20100199371
    Abstract: Novel proteins are provided herein, including proteins capable of catalyzing the acetylation of glyphosate and other structurally related proteins. Also provided are novel polynucleotides capable of encoding these proteins, compositions that include one or more of these novel proteins and/or polynucleotides, recombinant cells and transgenic plants comprising these novel compounds, diversification methods involving the novel compounds, and methods of using the compounds. Some of the novel methods and compounds provided herein can be used to render an organism, such as a plant, resistant to glyphosate.
    Type: Application
    Filed: August 3, 2009
    Publication date: August 5, 2010
    Applicants: Pioneer Hi-Bred International, Inc., Verdia, Inc., E.I. du Pont de Nemours and Company
    Inventors: Linda A. Castle, Dan Siehl, Lorraine Giver, Jeremy Minshull, Cristina Ivy, Yong Hong Chen, Phillip A. Patten, Nicholas B. Duck, Rebecca Gorton, Billy Fred McCutchen, Roger Kemble
  • ANTIBACTERIAL AGENTS
    Publication number: 20100190766
    Abstract: Antibacterial compounds of formula (I) are provided: as well as stereoisomers, pharmaceutically acceptable salts, esters, and prodrugs thereof; pharmaceutical compositions comprising such compounds; methods of treating bacterial infections by the administration of such compounds; and processes for the preparation of such compounds.
    Type: Application
    Filed: December 10, 2009
    Publication date: July 29, 2010
    Applicant: Achaogen, Inc.
    Inventors: Heinz E. Moser, Qing Lu, Phillip A. Patten, Dan Wang, Ramesh Kasar, Stephen Kaldor, Brian D. Patterson
  • OLIGONUCLEOTIDE MEDIATED NUCLEIC ACID RECOMBINATION
    Publication number: 20100184627
    Abstract: Methods of recombining nucleic acids, including homologous nucleic acids, are provided. Families of gene shuffling oligonucleotides and their use in recombination procedures, as well as polymerase and ligase mediated recombination methods are also provided.
    Type: Application
    Filed: September 11, 2009
    Publication date: July 22, 2010
    Applicant: Maxygen, Inc.
    Inventors: Andreas Crameri, Willem P.C. Stemmer, Jeremy Minshull, Steven H. Bass, Mark Welch, John E. Ness, Claes Gustafsson, Phillip A. Patten
  • NOVEL GLYPHOSATE-N-ACETYLTRANSFERASE (GAT) GENES
    Publication number: 20100184204
    Abstract: Novel proteins are provided herein, including proteins capable of catalyzing the acetylation of glyphosate and other structurally related proteins. Also provided are novel polynucleotides capable of encoding these proteins, compositions that include one or more of these novel proteins and/or polynucleotides, recombinant cells and transgenic plants comprising these novel compounds, diversification methods involving the novel compounds, and methods of using the compounds. Some of the novel methods and compounds provided herein can be used to render an organism, such as a plant, resistant to glyphosate.
    Type: Application
    Filed: April 1, 2009
    Publication date: July 22, 2010
    Applicants: Verdia, Inc., Pioneer Hi-Bred International, Inc., E.I. Du Pont De Nemours
    Inventors: Linda A. Castle, Dan Sichl, Lorraine Giver, Jeremy Minshull, Cristina Ivy, Yong Hong Chen, Phillip A. Patten, Rebecca Gorton, Nicholas B. Duck, Billy Fred McCutchen, Roger Kemble
  • Methods, systems, and software for identifying functional biomolecules
    Patent number: 7751986
    Abstract: The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods.
    Type: Grant
    Filed: October 30, 2007
    Date of Patent: July 6, 2010
    Assignee: Maxygen, Inc.
    Inventors: Claes Gustafsson, Sridhar Govindarajan, Robin A. Emig, Richard John Fox, Ajoy K. Roy, Jeremy S. Minshull, S. Christopher Davis, Anthony R. Cox, Phillip A. Patten, Linda A. Castle, Daniel L. Siehl, Rebecca Lynne Gorton, Teddy Chen
  • Methods, systems, and software for identifying functional biomolecules
    Patent number: 7747391
    Abstract: The present invention generally relates to methods of rapidly and efficiently searching biologically-related data space. More specifically, the invention includes methods of identifying bio-molecules with desired properties, or which are most suitable for acquiring such properties, from complex bio-molecule libraries or sets of such libraries. The invention also provides methods of modeling sequence-activity relationships. As many of the methods are computer-implemented, the invention additionally provides digital systems and software for performing these methods.
    Type: Grant
    Filed: July 29, 2003
    Date of Patent: June 29, 2010
    Assignee: Maxygen, Inc.
    Inventors: Claes Gustafsson, Sridhar Govindarajan, Robin A. Emig, Richard John Fox, Ajoy K. Roy, Jeremy S. Minshull, S. Christopher Davis, Anthony R. Cox, Phillip A. Patten, Linda A. Castle, Daniel L. Siehl, Rebecca Lynne Gorton, Teddy Chen
  • Glyphosate-N-acetyltransferase (GAT) genes
    Patent number: 7714188
    Abstract: Novel proteins are provided herein, including proteins capable of catalyzing the acetylation of glyphosate and other structurally related proteins. Also provided are novel polynucleotides capable of encoding these proteins, compositions that include one or more of these novel proteins and/or polynucleotides, recombinant cells and transgenic plants comprising these novel compounds, diversification methods involving the novel compounds, and methods of using the compounds. Some of the novel methods and compounds provided herein can be used to render an organism, such as a plant, resistant to glyphosate.
    Type: Grant
    Filed: May 12, 2006
    Date of Patent: May 11, 2010
    Assignees: Pioneer Hi-Bred Int'l., Inc., Verdia, Inc.
    Inventors: Linda A. Castle, Dan Siehl, Lorraine Giver, Jeremy Minshull, Cristina Ivy, Yong Hong Chen, Nicholas B. Duck, Phillip A. Patten, Rebecca Gorton
  • Glyphosate-N-acetyltransferase (GAT) genes
    Patent number: 7709702
    Abstract: Novel proteins are provided herein, including proteins capable of catalyzing the acetylation of glyphosate and other structurally related proteins. Also provided are novel polynucleotides capable of encoding these proteins, compositions that include one or more of these novel proteins and/or polynucleotides, recombinant cells and transgenic plants comprising these novel compounds, diversification methods involving the novel compounds, and methods of using the compounds. Some of the novel methods and compounds provided herein can be used to render an organism, such as a plant, resistant to glyphosate.
    Type: Grant
    Filed: May 12, 2006
    Date of Patent: May 4, 2010
    Assignees: Pioneer Hi-Bred Int'l., Inc., E.I. duPont de Nemours and Co., Verdia, Inc.
    Inventors: Linda A. Castle, Dan Siehl, Lorraine Giver, Jeremy Minshull, Cristina Ivy, Yong Hong Chen, Nicholas B. Duck, Phillip A. Patten, Rebecca Gorton, Billy Fred McCutchen, Roger Kemble
  • METHODS FOR IDENTIFYING SETS OF OLIGONUCLEOTIDES FOR USE IN AN IN VITRO RECOMBINATION PROCEDURE
    Publication number: 20100056385
    Abstract: In silico nucleic acid recombination methods, related integrated systems utilizing genetic operators and libraries made by in silico shuffling methods are provided.
    Type: Application
    Filed: September 10, 2009
    Publication date: March 4, 2010
    Applicant: MAXYGEN, INC.
    Inventors: Sergey A. Selifonov, Willem P.C. Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip A. Patten, Jeremy Minshull, Lorraine J. Giver
  • Glyphosate-N-acetyltransferase (GAT) genes
    Patent number: 7666643
    Abstract: Novel proteins are provided herein, including proteins capable of catalyzing the acetylation of glyphosate and other structurally related proteins. Also provided are novel polynucleotides capable of encoding these proteins, compositions that include one or more of these novel proteins and/or polynucleotides, recombinant cells and transgenic plants comprising these novel compounds, diversification methods involving the novel compounds, and methods of using the compounds. Some of the novel methods and compounds provided herein can be used to render an organism, such as a plant, resistant to glyphosate.
    Type: Grant
    Filed: August 16, 2006
    Date of Patent: February 23, 2010
    Assignees: Pioneer Hi-Bred international, Inc., Verdia, Inc.
    Inventors: Linda A. Castle, Dan Siehl, Lorraine Giver, Jeremy Minshull, Cristina Ivy, Yong Hong Chen, Nicholas B. Duck, Phillip A. Patten
  • Glyphosate-N-acetyltransferase (GAT) genes
    Patent number: 7666644
    Abstract: Novel proteins are provided herein, including proteins capable of catalyzing the acetylation of glyphosate and other structurally related proteins. Also provided are novel polynucleotides capable of encoding these proteins, compositions that include one or more of these novel proteins and/or polynucleotides, recombinant cells and transgenic plants comprising these novel compounds, diversification methods involving the novel compounds, and methods of using the compounds. Some of the novel methods and compounds provided herein can be used to render an organism, such as a plant, resistant to glyphosate.
    Type: Grant
    Filed: December 19, 2006
    Date of Patent: February 23, 2010
    Assignees: Verdia, Inc., E.I. du Pont de Nemours & Company, Pioneer Hi-Bred International, Inc.
    Inventors: Linda A. Castle, Dan Siehl, Lorraine Giver, Jeremy Minshull, Christina Ivy, Yong Hong Chen, Phillip A. Patten, Rebecca Gorton, Nicholas B. Duck
  • NOVEL GLYPHOSATE-N-ACETYLTRANSFERASE (GAT) GENES
    Publication number: 20090325804
    Abstract: Novel proteins are provided herein, including proteins capable of catalyzing the acetylation of glyphosate and other structurally related proteins. Also provided are novel polynucleotides capable of encoding these proteins, compositions that include one or more of these novel proteins and/or polynucleotides, recombinant cells and transgenic plants comprising these novel compounds, diversification methods involving the novel compounds, and methods of using the compounds. Some of the novel methods and compounds provided herein can be used to render an organism, such as a plant, resistant to glyphosate.
    Type: Application
    Filed: August 3, 2009
    Publication date: December 31, 2009
    Applicants: Pioneer Hi-Bred International, Inc., Verdia, Inc., E.I. du Pont de Nemours and Company
    Inventors: Linda A. Castle, Dan Siehl, Lorraine Giver, Jeremy Minshull, Cristina Ivy, Yong Hong Chen, Phillip A. Patten, Nicholas B. Duck, Rebecca Gorton, Billy Fred McCutchen, Roger Kemble
  • Evolution of whole cells and organisms by recursive sequence recombination
    Patent number: 7629170
    Abstract: The invention provides methods employing iterative cycles of recombination and selection/screening for evolution of whole cells and organisms toward acquisition of desired properties. Examples of such properties include enhanced recombinogenicity, genome copy number, and capacity for expression and/or secretion of proteins and secondary metabolites.
    Type: Grant
    Filed: August 17, 2006
    Date of Patent: December 8, 2009
    Assignee: Maxygen, Inc.
    Inventors: Stephen delCardayre, Matthew B. Tobin, Willem P. C. Stemmer, Jon E. Ness, Jeremy S. Minshull, Phillip A. Patten, Venkiteswatan Mani Subramanian, Linda A. Castle, Claus M. Krebber, Steven H. Bass, Ying-Xin Zhang, Anthony R. Cox, Gjalt W. Huisman, Ling Yuan, Joseph A. Affholter
  • NOVEL GLYPHOSATE-N-ACETYLTRANSFERASE (GAT) GENES
    Publication number: 20090298714
    Abstract: Novel proteins are provided herein, including proteins capable of catalyzing the acetylation of glyphosate and other structurally related proteins. Also provided are novel polynucleotides capable of encoding these proteins, compositions that include one or more of these novel proteins and/or polynucleotides, recombinant cells and transgenic plants comprising these novel compounds, diversification methods involving the novel compounds, and methods of using the compounds. Some of the novel methods and compounds provided herein can be used to render an organism, such as a plant, resistant to glyphosate.
    Type: Application
    Filed: August 3, 2009
    Publication date: December 3, 2009
    Applicants: Pioneer Hi-Bred International, Inc., Verdia, Inc., E.I. du Pont de Nemours and Company
    Inventors: Linda A. Castle, Dan Siehl, Lorraine Giver, Jeremy Minshull, Christina Ivy, Yong Hong Chen, Phillip A. Patten, Rebecca Gorton, Nicholas B. Duck, Billy Fred McCutchen, Roger Kemble
  • Methods for identifying sets of oligonucleotides for use in an in vitro recombination procedure
    Patent number: 7620502
    Abstract: In silico nucleic acid recombination methods, related integrated systems utilizing genetic operators are used to identify sets of oligonucleotides for in vitro recombination.
    Type: Grant
    Filed: January 24, 2006
    Date of Patent: November 17, 2009
    Assignee: Maxygen, Inc.
    Inventors: Sergey A. Selifonov, Willem P. C. Stemmer, Claes Gustafsson, Matthew Tobin, Stephen del Cardayre, Phillip A. Patten, Jeremy Minshull, Lorraine J. Giver
  • Evolved interferon-alpha polypeptides
    Patent number: 7619067
    Abstract: The present invention provides evolved interferon-alpha polypeptides, and conjugates thereof, and nucleic acids encoding the polypeptides. The invention also includes compositions comprising these polypeptides, conjugates, and nucleic acids; cells containing or expressing the polypeptides, conjugates, and nucleic acids; methods of making the polypeptides, conjugates, and nucleic acids; and methods of using the polypeptides, conjugates, and nucleic acids.
    Type: Grant
    Filed: May 17, 2006
    Date of Patent: November 17, 2009
    Assignee: Maxygen, Inc.
    Inventors: Madan M. Paidhungat, Ian J. Sas, Thomas Bouquin, David Lin, Teddy Chen, Douglas Guptill, Amy Brideau-Andersen, Steven H. Bass, Phillip A. Patten