Abstract: A vacuum filter device comprising a filter body having two holders on opposite sides of a filter. Each holder contains a closed container in a fluid-tight, sealed relationship. The filter is retained by a compression sealing element and the sealing element is maintained in place by a compression element formed of a ring. The compression element is bonded to a portion of the body to hold it, the sealing element and filter in place under a compression seal. Optionally a port in the compression element is formed to align with the vent of the device. Further, an alignment feature on the compression element ensures the port is in alignment with the vent of the device. The device also includes a vacuum port communicating with the downstream side of the filter, and hence the filtrate container.

Abstract: A device includes a control cover having a body portion with a first surface. The control cover also has at least one cavity in the first surface. The control cover may include a plurality of prongs, each of which extends, from the first surface, along a respective axis that intersects the first surface. At least one prong of the plurality of prongs includes a respective aperture configured to receive a locking mechanism. The control cover may include a compressible material disposed within the cavity that fills at least a portion of the cavity. The control cover may include at least one aperture configured to receive at least one locking mechanism.

Abstract: A removable guiding apparatus, placed on a trailer hitch extension, that will force the tongue of a trailer over the trailer hitch ball. This system is designed such that the positioning components will force the trailer tongue into position over the hitch ball should the tongue and hitch ball be slightly out of alignment during the backing of the vehicle toward the trailer tongue. These positioning components can be easily placed upon and removed from a plate that is permanently attached to the underside of the trailer hitch extension and hitch ball. The ability to remove these positioning components allows for a wide swing of the trailer tongue during towing as well as unobstructed access to the hitch area.

Abstract: Systems, methods, apparatuses, and software for data storage systems are provided herein. In one example, a data storage platform includes one or more data storage modules each comprising storage drives coupled over a Peripheral Component Interconnect Express (PCIe) fabric with at least one processing module that receives storage operations directed to the one or more data storage modules over one or more network interfaces. The processing module is configured to assign service levels in a queue to the storage operations that are received over the one or more network interfaces. Based at least on the service levels, the processing module is configured to service the storage operations from the queue with the one or more data storage modules over the PCIe fabric.

Abstract: Fluid containment pressure vessel that eliminates the outer support housing present in certain conventional vessels, and provides an improved cap-to-body interface. In certain embodiments, the cap is threaded and configured to threadingly engage with the body of the pressure vessel, and has sufficient structural integrity to withstand the pressures in the device without the need for a support housing. In certain embodiments, an interlock mechanism is provided that prevents the cap from being opened (e.g., removed from the body) while the device is under pressure. In certain embodiments, a pressure relief valve is provided with a pre-loaded biasing mechanism to achieve the required pressure release rate. The vessel can be used for sample preparation, including purification or concentration of samples, particularly protein samples.

Abstract: There is disclosed a camber-lock apparatus that provides for both joining and separating a two part hole saw. Said camber-lock apparatus consist of a circuited plate that installs within the boundaries of clasping devises at the top of a cylindrical saw blade. The cylindrical saw blade, with the cutting or teeth edge at the bottom, has a large opening at the top. Within the interior circumference of said opening is attached a series of clasping devices. Said circuited plate, with its attached arbor and pilot bit, comprises the top elements of the saw; which can be rotated into and out of place within the boundaries of said clasping devises. The purpose for removal of said circuited plate is to exposes the interior of the saw and any material jammed therein; thereby allowing for easy removal of said material.

Abstract: The embodiments disclosed herein are directed to an apparatus useful in conducting detection of compounds on blotting membranes. The device is comprised of several layers including a porous support layer below the blotting membrane(s), a flow distributor above the blotting membrane(s) and optionally a well on the flow distributor to contain the liquid to the desired area and to allow for lower starting volumes of such liquid. Preferably, the flow distributor is a non-binding or low binding hydrophilic porous membrane such as a 0.22 micron membrane and the support layer is a grid or sintered porous material. The distributor and support are held together to form an envelope around the membrane(s). The use of a hinge, clips and other such devices is preferred in doing so.

Abstract: The present invention is a cell cultivating vessel or device, such as a single or multitier flask, including a cover having a top plate, a side wall and a resealable port; an intermediate tray for receiving cells and cell culture media, having a bottom plate, a side wall, and a gap region formed between an interior upwardly angled lip located on an interior portion of the intermediate tray bottom plate and an adjacent outwardly angled side wall portion of the intermediate tray bottom plate, wherein the lip has a outwardly swooping curvilinear edge feature; and a base tray for receiving the cells and cell culture media, including a bottom plate and a side wall.

Abstract: Sample preparation device that allows for a complete bind, wash, elute, buffer-exchange and concentration process to be carried out without sample transfer between multiple devices. The device includes a reservoir, a column for holding chromatography media, a holder region for holding a filtration device, and an outlet. The filtration device plugs into the holder region of the centrifugal device, and the assembly can be placed in an optional holder. The assembly, with or without the optional holder, can be placed in a conventional centrifuge tube for centrifugation. The entire bind, wash, elute, buffer exchange and concentration steps can be carried out with the apparatus without any pipette transfers (and the associated sample losses. The sample preparation device also can be used for binding and washing steps, in which case the filtration device is not needed, and for buffer exchange and concentration steps, in which case the media is not needed.

Abstract: Sample preparation device that allows for a complete bind, wash, elute, buffer-exchange and concentration process to be carried out without sample transfer between multiple devices. The device includes a reservoir, a column for holding chromatography media, a holder region for holding a filtration device, and an outlet. The filtration device plugs into the holder region of the centrifugal device, and the assembly can be placed in an optional holder. The assembly, with or without the optional holder, can be placed in a conventional centrifuge tube for centrifugation. The entire bind, wash, elute, buffer exchange and concentration steps can be carried out with the apparatus without any pipette transfers (and the associated sample losses. The sample preparation device also can be used for binding and washing steps, in which case the filtration device is not needed, and for buffer exchange and concentration steps, in which case the media is not needed.

Abstract: Systems, methods, apparatuses, and software for data storage systems are provided herein. In one example, a data storage system is provided that includes processing systems configured to receive storage operations for storage drives coupled over a communication fabric. The data storage system includes a control processor configured to establish a timer synchronization signal and distribute the timer synchronization signal to the processing systems. Each of the processing systems is configured to assign timestamps to received storage operations based on a timestamp counter synchronized among the processing systems using the timer synchronization signal. The processing systems are configured to order committing of the storage operations to the storage drives based at least on the timestamps associated with the storage operations.

Abstract: The embodiments disclosed herein are directed to an apparatus useful in conducting detection of compounds on blotting membranes. The device is comprised of several layers including a porous support layer below the blotting membrane(s), a flow distributor above the blotting membrane(s) and optionally a well on the flow distributor to contain the liquid to the desired area and to allow for lower starting volumes of such liquid. Preferably, the flow distributor is a non-binding or low binding hydrophilic porous membrane such as a 0.22 micron membrane and the support layer is a grid or sintered porous material. The distributor and support are held together to form an envelope around the membrane(s). The use of a hinge, clips and other such devices is preferred in doing so.

Abstract: Sample preparation device that allows for a complete bind, wash, elute, buffer-exchange and concentration process to be carried out without sample transfer between multiple devices. The device includes a reservoir, a column for holding chromatography media, a holder region for holding a filtration device, and an outlet. The filtration device plugs into the holder region of the centrifugal device, and the assembly can be placed in an optional holder. The assembly, with or without the optional holder, can be placed in a conventional centrifuge tube for centrifugation. The entire bind, wash, elute, buffer exchange and concentration steps can be carried out with the apparatus without any pipette transfers (and the associated sample losses. The sample preparation device also can be used for binding and washing steps, in which case the filtration device is not needed, and for buffer exchange and concentration steps, in which case the media is not needed.

Abstract: There is disclosed an automatic cleaning apparatus for a septic tank filter. The cleaning apparatus has a brush operable to move across a screen disposed internally of the filter. The brush is tethered, via a cable and at least one pulley, to a weighted float disposed in an effluent pump chamber associated with the septic tank. The brush therefore moves vertically across the screen with vertical changes the level of effluent in the septic tank.

Abstract: The present invention provides methods for quantitating one or more biomolecules in a sample using IR based techniques, sample holder devices for use in such methods as well as methods for manufacturing such sample holder devices.

Abstract: A vacuum filter device comprising a filter body having two holders on opposite sides of a filter. Each holder contains a closed container in a fluid-tight, sealed relationship. The filter is retained by a compression sealing element and the sealing element is maintained in place by a compression element formed of a ring. The compression element is bonded to a portion of the body to hold it, the sealing element and filter in place under a compression seal. Optionally a port in the compression element is formed to align with the vent of the device. Further, an alignment feature on the compression element ensures the port is in alignment with the vent of the device. The device also includes a vacuum port communicating with the downstream side of the filter, and hence the filtrate container.

Abstract: The present invention provides a vacuum filter device including a filter body having two holders on opposite sides of a filter. Each holder contains a closed container in a fluid-tight, sealed relationship. The filter is retained by a compression sealing element that resiliently applies sealing pressure to the upper surface of the filter. The sealing element is maintained in place by a compression element formed of a ring that applies a desired compressive force to the sealing element. The compression element is bonded to a portion of the body to hold it, the sealing element and filter in place and under a compression seal. The invention also can provide for an alignment feature on the compression element that ensures the port is in alignment with the vent of the device. The device also includes a vacuum port communicating with the downstream side of the filter, and hence the filtrate container.

Abstract: The invention is directed to an apparatus useful in conducting detection of compounds on blotting membranes. The device is comprised of several layers including a porous support layer below the blotting membrane(s), a flow distributor above the blotting membrane(s) and optionally a well on the flow distributor to contain the liquid to the desired area and to allow for lower starting volumes of such liquid. Preferably, the flow distributor is a non-binding or low binding hydrophilic porous membrane such as a 0.22 micron membrane and the support layer is a grid or sintered porous material. The distributor and support are held together to form an envelope around the membrane(s). The use of a hinge, clips and other such devices is preferred in doing so.

Abstract: The invention is directed to an apparatus useful in conducting detection of compounds on blotting membranes. The device is comprised of several layers including a porous support layer below the blotting membrane(s), a flow distributor above the blotting membrane(s) and optionally a well on the flow distributor to contain the liquid to the desired area and to allow for lower starting volumes of such liquid. Preferably, the flow distributor is a non-binding or low binding hydrophilic porous membrane such as a 0.22 micron membrane and the support layer is a grid or sintered porous material. The distributor and support are held together to form an envelope around the membrane(s). The use of a hinge, clips and other such devices is preferred in doing so.

Abstract: Sample preparation device that allows for a complete bind, wash, elute, buffer-exchange and concentration process to be carried out without sample transfer between multiple devices. The device includes a reservoir, a column for holding chromatography media, a holder region for holding a filtration device, and an outlet. The filtration device plugs into the holder region of the centrifugal device, and the assembly can be placed in an optional holder. The assembly, with or without the optional holder, can be placed in a conventional centrifuge tube for centrifugation. The entire bind, wash, elute, buffer exchange and concentration steps can be carried out with the apparatus without any pipette transfers (and the associated sample losses. The sample preparation device also can be used for binding and washing steps, in which case the filtration device is not needed, and for buffer exchange and concentration steps, in which case the media is not needed.