Abstract: The present disclosure relates to the combination of IN10018 and an epidermal growth factor receptor tyrosine kinase inhibitor for the treatment of tumors.

Abstract: The disclosure features compounds comprising an antigen portion, a soluble Major Histocompatibility Complex (MHC) molecule portion (e.g., all or an antigen-binding portion of a soluble MHC class I molecule), and a dynamic anchor portion (e.g., an agent, such as Annexin V, that binds to phosphatidylserine). The featured compounds are useful for a variety of therapeutic applications, including, e.g., enhancing a T cell response to an antigen of interest or enhancing a T cell-driven immune response by a subject to an antigen of interest (e.g., a cancer antigen or a microbial antigen).

Abstract: A biosensor system determines analyte concentration from an output signal generated from a light-identifiable species or a redox reaction of the analyte. The biosensor system compensates at least 50% of the total error in the output signal with a primary function and compensates a portion of the remaining error with a residual function. The amount of error compensation provided by the primary and residual functions may be adjusted with a weighing coefficient. The compensation method including a primary function and a residual function may be used to determine analyte concentrations having improved accuracy from output signals including components attributable to error.

Abstract: An embodiment method includes: forming fins extending from a semiconductor substrate; depositing an inter-layer dielectric (ILD) layer on the fins; forming masking layers on the ILD layer; forming a cut mask on the masking layers, the cut mask including a first dielectric material, the cut mask having first openings exposing the masking layers, each of the first openings surrounded on all sides by the first dielectric material; forming a line mask on the cut mask and in the first openings, the line mask having slot openings, the slot openings exposing portions of the cut mask and portions of the masking layers, the slot openings being strips extending perpendicular to the fins; patterning the masking layers by etching the portions of the masking layers exposed by the first openings and the slot openings; and etching contact openings in the ILD layer using the patterned masking layers as an etching mask.

Abstract: A capacitive biosensor is provided. The capacitive biosensor includes: a transistor, an interconnect structure on the transistor, and a passivation layer on the interconnect structure. The interconnect structure includes a first metal structure on the transistor, a second metal structure on the first metal structure, and a third metal structure on the second metal structure. The third metal structure includes a first conductive layer, a second conductive layer, and a third conductive layer that are sequentially stacked. The passivation has an opening exposing a portion of the third metal structure. The capacitive biosensor further includes a sensing region on the interconnect structure. The sensing region includes a first sensing electrode and a second sensing electrode. The first sensing electrode is formed of the third conductive layer, and the second sensing electrode is disposed on the passivation layer.

Abstract: An image sensor, electronic device and method thereof that performs on-sensor multiresolution deep neural network (DNN) processing, such as for gesture recognition. The image data is transformed into first resolution type image data and second resolution type image data. Based on detecting the first resolution type image data includes a predetermined object, processing the second resolution type image data using the second resolution type image data as input into the second DNN.

Abstract: The present invention relates to a steel wire and transmission shaft connecting structure, a surgical robot, and a method. A base is included. Multiple transmission shafts penetrate through the base. A clamping block is arranged at one end of the transmission shaft. The transmission shaft is detachably clamped and fixed to a quick-connect shaft through the clamping block and a clamping slot structure arranged at one end of the quick-connect shaft. The other end of the quick-connect shaft penetrates through a butting seat and is then detachably fixed to a steel wire extending from a pipeline member. A shifting clamp is arranged between the butting seat and the pipeline member. The shifting clamp is provided with a through hole configured for the butting shaft to penetrate through. The through hole is composed of a first hole portion and a second hole portion.

Abstract: A user equipment may receive a configuration message comprising at least one of: a configured grant configuration, or a semi-persistent scheduling configuration, wherein configuration may be associated with a cross-division duplexing slot format, wherein the cross-division duplexing slot format may comprise at least one of: a cross-division duplexing time slot for concurrent transmission in a plurality of communication directions, or a cross-division duplexing time slot for transmission in one communication direction; receive an information indicating at least one resource of the configuration; determine whether the at least one resource is valid, based on a comparison between a corresponding cross-division duplexing slot format of the at least one resource and the cross-division duplexing slot format associated with the configuration; and perform communication with the network device on the at least one resource based, at least partially, on a determination that the at least one resource is valid.

Abstract: A process for pyrolysis of a mixed plastic stream that contains polyvinyl chloride (PVC) is provided in which the chloride from PVC is removed from an initial melting reactor that melts the mixed plastic stream. Chloride is removed in a vapor stream from the initial melting reactor with additional chloride removed from addition of sorbents to the pyrolysis reactor and in adsorbent beds downstream of the pyrolysis reactor. The pyrolysis reactor has a configuration comprising two cylindrical ring structures, an inner cylindrical ring structure within an outer cylindrical ring structure wherein a circulation liquid supply stream enters said pyrolysis reactor tangentially relative to a ring edge of said two cylindrical ring structures and wherein solid particles move in a downward direction to a bottom of the pyrolysis reactor.

Abstract: Presented herein are embodiments of a fast search on graph methodology for Maximum Inner Product Search (MIPS). This optimization problem is challenging since traditional Approximate Nearest Neighbor (ANN) search methods may not perform efficiently in the nonmetric similarity measure. Embodiments herein are based on the property that a Möbius/Möbius-like transformation introduces an isomorphism between a subgraph of 2-Delaunay graph and Delaunay graph for inner product. Under this observation, embodiments of a novel graph indexing and searching methodology are presented to find the optimal solution with the largest inner product with the query. Experiments show significant improvements compared to existing methods.

Abstract: The invention relates to a concealed door handle and a vehicle. The concealed door handle comprises: a handle body; a handle base fixed in a body of a vehicle, the handle body being concealed in the handle base, and the handle body being rotatably connected to the handle base; and a deployment microswitch arranged on the handle base and configured to detect a deployed position of the handle body and to maintain communication with a vehicle control module, wherein when the deployment microswitch jumps from a triggered state into an untriggered state, the deployment microswitch sends an input signal for unlocking an electronic lock to the vehicle control module. The concealed door handle of the invention has a simple structure and low costs, and a signal source can be arranged in a limited structural space.

Abstract: A fingerprint sensing system comprising a plurality of conductive selection lines; a plurality of conductive read-out lines crossing the selection lines; selection circuitry controllable to provide a selection signal on at least one selected selection line in the plurality of selection lines; a plurality of pixel elements formed at intersections between the selection lines and the read-out lines; current providing circuitry coupled to the read-out lines and controllable to generate a current pulse in at least one of the read-out lines when reading out a sensing signal from each of the pixel elements.

Abstract: A method of cleaning includes placing a semiconductor device manufacturing tool component made of quartz on a support. A cleaning fluid inlet line is attached to a first open-ended tubular quartz projection extending from an outer main surface of the semiconductor device manufacturing tool component. A cleaning fluid is applied to the semiconductor device manufacturing tool component by introducing the cleaning fluid through the cleaning fluid inlet line and the tubular quartz projection.

Abstract: Embodiments of the present disclosure provide a system for continuous scanning monitoring and analysis based on a discrete three-dimensional fluorescence technology. The system comprises a high-pressure capillary gel electrophoresis mechanism configured to enable passages of different lengths of STR sequence fragments and nucleic acid gene fragments in an energized state; a sampling window unit configured to assemble a plurality of capillary tubes and a plurality of detection optical fibers shared by an excitation light and excited light; and a detection window unit configured to assemble the plurality of detection optical fibers and a fluorescence signal detection unit. The fluorescence signal detection unit is configured to output a plurality of single excitation light sources and obtain fluorescence signals.

Abstract: A method for continuous software delivery includes: receiving user selections of a first and second segments of a plurality of continuous delivery segments; generating a first toolchain including a plurality of tools configured based on one or more toolchain rules without input from a user; determining a segment dependency between the first segment and the second segment in response to the second user input; generating and executing an instance of a continuous delivery pipeline model including at least the first segment and the second segment; triggering at least a portion of the first toolchain to perform a continuous delivery action associated with the continuous delivery pipeline model; automatically reconfiguring one or more of the plurality of tools based on the one or more retrieved configuration rules; and performing an adjustment to the toolchain in response to the automatically reconfiguring one or more of the plurality of tools.

Abstract: A speed-command generating unit incorporated with an electric vehicle having a throttle module, a mechanical brake and a motor is disclosed and includes: a computation module for generating a computation value of a speed-command according to a throttle operating signal from the throttle module, a sensing module for detecting an activated status of the mechanical brake, a selecting module for providing a braking approach selecting signal, a trimming module for setting a trimming flag according to the activated status of the mechanical brake of last cycle, and a switching module connected therewith. The switching module generates different output values of the speed-command for the motor according to different foundations depending on the content of the trimming flag when the mechanical brake is inactivated in this cycle, and generates the output value according to the content of the braking approach selecting signal when the mechanical brake is activated in this cycle.

Abstract: A structure includes a substrate, a transistor, a contact, an oxygen-free etch stop layer, an oxygen-containing etch stop layer, a dielectric layer, and a via. The transistor is on the substrate. The contact is on a source/drain region of the transistor. The oxygen-free etch stop layer spans the contact. The oxygen-containing etch stop layer extends along a top surface of the oxygen-free etch stop layer. The dielectric layer is over the oxygen-containing etch stop layer. The via passes through the dielectric layer, the oxygen-containing etch stop layer, and the oxygen-free etch stop layer and lands on the contact. The memory stack lands on the via.

Abstract: Wireless communications systems and methods related to applying an uplink (UL) cancellation indication are provided. A UE may receive downlink control information (DCI) from a base station (BS). The DCI may include an uplink (UL) cancellation indication that references a plurality of resources in one or more full-UL slots and one or more full-duplex slots. The UE may refrain, based on the UL cancellation indication, from transmitting a communication in at least one of a first resource of the plurality of resources in the one or more full-UL slots or a second resource of the plurality of resources in the one or more full-duplex slots. Other aspects and features are also described.

Abstract: A transaction harmony degree-based method and system for transaction matching between a power grid and building energy. The method includes: obtaining a transaction harmony degree of a historical transaction cycle; sending, by using a blockchain, the transaction harmony degree to a corresponding building energy user, and sending a maximum compensated electricity price and an expected compensated electricity price in peak-valley regulation to all building energy users; determining, by each building energy user, a transaction-based compensated electricity price in the peak-valley regulation based on the received transaction harmony degree and the received maximum compensated electricity price and expected compensated electricity price in the peak-valley regulation, and feeding back the transaction-based compensated electricity price in the peak-valley regulation to a power grid; and determining, by the power grid, a building energy user that successfully performs transaction matching with the power grid.

Abstract: Embodiments of the present disclosure relate to methods, devices and computer readable storage medium for tracing an attack source in a service function chain overlay network. In example embodiments, a request for tracing an attack source of an attacking data is sent at the attack tracer to a first service function chain domain of a plurality of service function chain domains through which the attacking data flow passes subsequently. The request includes flow characteristics of the attacking data flow. Then, the attack tracer receives a first set of results of flow matching based on the flow characteristics from the first service function chain domain. The attack tracer identifies the attack source in the plurality of service function chain domains at least in part based on the first set of results. In this way, the attack source may be traced efficiently in the service function chain overlay network.