Patents by Inventor Qin Lin
Qin Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11952368Abstract: Provided are a fibroblast activation protein inhibitor (FAPI) dimer compound, an FAPI dimer-based positron emission tomography (PET) imaging agent for tumor diagnosis, and a preparation method and use thereof. An amphiphilic polyethylene glycol (PEG) chain and a dimerized structure of FAPI in the FAPI dimer compound with a structure shown in formula I can improve the in vivo kinetic properties of the compound and prolong a residence time of the compound in a tumor, thereby improving the uptake and imaging effects in the tumor. The accurate tumor diagnosis can be achieved by labeling the FAPI dimer compound with a diagnostic nuclide (68Ga), which has promising application prospects in PET imaging for diagnosis and in the preparation of a therapeutic nuclide (such as 177Lu or 90Y)-labeled drug for treating a FAP-?-expressing tumor.Type: GrantFiled: September 29, 2022Date of Patent: April 9, 2024Assignee: Xiamen UniversityInventors: Haojun Chen, Liang Zhao, Qin Lin, Kaili Fu, Yizhen Pang, Zhide Guo, Jianyang Fang, Long Sun, Hua Wu
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Patent number: 11934549Abstract: One or more implementations of the present specification provide an invoice access method and apparatus based on a blockchain, and an electronic device. The method includes: generating first ciphertext data by encrypting plaintext data of the target invoice based on a first key corresponding to an invoice issuer; generating second ciphertext data by encrypting the plaintext data of the target invoice based on a second key corresponding to an invoice receiver; adding the first ciphertext data and an user identifier of the invoice issuer to the blockchain as related to one another; and adding the second ciphertext data and an user identifier of the invoice receiver to the blockchain as related to one another.Type: GrantFiled: August 31, 2021Date of Patent: March 19, 2024Assignee: Advance New Technologies Co., Ltd.Inventors: Hansong Xiao, Ping Zhang, Wenhu Kan, Qin Liu, Liangrong Lin, Fuxi Deng, Yixiang Zhang, Rui Chen, Jinming Duan
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Publication number: 20230383080Abstract: Compositions are provided including an uncrosslinked thermoplastic nitrogen-containing matrix material and composite particles distributed in the matrix material. The composite particles each include a chemical blowing agent particle encapsulated within a shell including an uncrosslinked thermoplastic material. The uncrosslinked thermoplastic material exhibits at least a certain minimum complex viscosity at a decomposition temperature of the chemical blowing agent particle. Also described are foam compositions and articles including the foam compositions, such as a sheet or multilayer construction. Composite particles are further provided. Methods of making the foam compositions are additionally described herein. Also, polishing pads, polishing systems, and methods of polishing a substrate are provided.Type: ApplicationFiled: August 15, 2023Publication date: November 30, 2023Inventors: Joshua M. Fishman, Jeffrey P. Kalish, Caitlin E. Meree, Qin Lin, Nicholas K. Lee, Li Yao, Rajdeep S. Kalgutkar, Duy K. Lehuu, David T. Amos
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Patent number: 11767406Abstract: Compositions are provided including an uncrosslinked thermoplastic nitrogen-containing matrix material and composite particles distributed in the matrix material. The composite particles each include a chemical blowing agent particle encapsulated within a shell including an uncrosslinked thermoplastic material. The uncrosslinked thermoplastic material exhibits at least a certain minimum complex viscosity at a decomposition temperature of the chemical blowing agent particle. Also described are foam compositions and particles including the foam compositions, such as a sheet or multilayer construction. Composite particles are further provided. Methods of making the foam compositions are additionally described herein. Also, polishing pads, polishing systems, and methods of polishing a substrate are provided.Type: GrantFiled: June 9, 2020Date of Patent: September 26, 2023Assignee: 3M Innovative Properties CompanyInventors: Joshua M. Fishman, Jeffrey P. Kalish, Caitlin E. Meree, Qin Lin, Nicholas K. Lee, Li Yao, Rajdeep S. Kalgutkar, Duy K. Lehuu, David T. Amos
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Publication number: 20230264048Abstract: Disclosed are a method and an apparatus for controlling multileaf collimator in radiotherapy. The method comprises: acquiring a preset model; outputting, regarding a radiotherapy target, a target leaf sequence of a multileaf collimator through the preset model, to obtain a planning file; and importing the planning file into a radiotherapy planning system to control a linear accelerator to operate, so as to implement a radiotherapy plan, which solves the technical problem in the related art of poor accuracy and stability in determining a leaf sequence of a multileaf collimator.Type: ApplicationFiled: November 26, 2020Publication date: August 24, 2023Inventors: Qichao ZHOU, Wei ZHANG, Lingke KONG, Liwan SHI, Qin LIN
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Publication number: 20230204676Abstract: A portable battery detection device includes a battery data receiving module for receiving battery data, a temperature measurement module for measuring battery temperature, a gas measurement module for measuring discharged gas, an insulation resistance measurement module for measuring insulation resistance, a serial impedance measurement module for measuring serial impedance, a data acquisition module for receiving various data sent by the temperature measurement module and the gas measurement module, an electric meter module for measuring DC voltage, current, and impedance, the data integration module for receiving data transmitted by the battery data receiving module, the electric meter module, and the insulation resistance measurement module, and then integrating the data to the processor module, and the processor module for using data received from the data integration module, the data acquisition module, and the serial impedance measurement module to transmit data, control, and manage the operation of thType: ApplicationFiled: December 29, 2021Publication date: June 29, 2023Inventors: DAO-QIN LIN, WEI-MIN HSIAO, SHIH-CHANG TSENG, CHIH-HSIEN CHUNG, GWO-HUEI YOU, KUO-KUANG JEN
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Patent number: 11675018Abstract: A portable battery detection device includes a battery data receiving module for receiving battery data, a temperature measurement module for measuring battery temperature, a gas measurement module for measuring discharged gas, an insulation resistance measurement module for measuring insulation resistance, a serial impedance measurement module for measuring serial impedance, a data acquisition module for receiving various data sent by the temperature measurement module and the gas measurement module, an electric meter module for measuring DC voltage, current, and impedance, the data integration module for receiving data transmitted by the battery data receiving module, the electric meter module, and the insulation resistance measurement module, and then integrating the data to the processor module, and the processor module for using data received from the data integration module, the data acquisition module, and the serial impedance measurement module to transmit data, control, and manage the operation of thType: GrantFiled: December 29, 2021Date of Patent: June 13, 2023Assignee: NATIONAL CHUNG SHAN INSTITUTE OF SCIENCE AND TECHNOLOGYInventors: Dao-Qin Lin, Wei-Min Hsiao, Shih-Chang Tseng, Chih-Hsien Chung, Gwo-Huei You, Kuo-Kuang Jen
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Publication number: 20230105190Abstract: The present disclosure relates to the technical field of medicine, and in particular to a fibroblast activation protein inhibitor (FAPI) dimer compound, an FAPI dimer-based positron emission tomography (PET) imaging agent for tumor diagnosis, and a preparation method and use thereof An amphiphilic polyethylene glycol (PEG) chain and a dimerized structure of FAPI in the FAPI dimer compound with a structure shown in formula I provided by the present disclosure can improve the in vivo kinetic properties of the compound and prolong a residence time of the compound in a tumor, thereby improving the uptake and imaging effects in the tumor. The accurate tumor diagnosis can be achieved by labeling the FAPI dimer compound with a diagnostic nuclide (68Ga), which has promising application prospects in PET imaging for diagnosis and in the preparation of a therapeutic nuclide (such as 177Lu or 90Y)-labeled drug for treating a FAP-?-expressing tumor.Type: ApplicationFiled: September 29, 2022Publication date: April 6, 2023Applicant: XIAMEN UNIVERSITYInventors: Haojun CHEN, Liang ZHAO, Qin LIN, Kaili FU, Yizhen PANG, Zhide GUO, Jianyang FANG, Long SUN, Hua WU
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Publication number: 20220177663Abstract: Compositions are provided including an uncrosslinked thermoplastic nitrogen-containing matrix material and composite particles distributed in the matrix material. The composite particles each include a chemical blowing agent particle encapsulated within a shell including an uncrosslinked thermoplastic material. The uncrosslinked thermoplastic material exhibits at least a certain minimum complex viscosity at a decomposition temperature of the chemical blowing agent particle. Also described are foam compositions and particles including the foam compositions, such as a sheet or multilayer construction. Composite particles are further provided. Methods of making the foam compositions are additionally described herein. Also, polishing pads, polishing systems, and methods of polishing a substrate are provided.Type: ApplicationFiled: June 9, 2020Publication date: June 9, 2022Inventors: Joshua M. Fishman, Jeffrey P. Kalish, Caitlin E. Meree, Qin Lin, Nicholas K. Lee, Li Yao, Rajdeep S. Kalgutkar, Duy K. Lehuu, David T. Amos
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Publication number: 20220023991Abstract: A polishing pad includes a polishing layer having a first major surface and a second major surface opposite the first major surface. The polishing pad further includes a subpad, which is coupled to the polishing layer, and has a first major surface and a second major surface opposite the first major surface. At least 50% of the subpad, based on the total surface area of the first major surface of the subpad, is optically transparent.Type: ApplicationFiled: November 22, 2019Publication date: January 27, 2022Inventors: Duy K. Lehuu, Qin Lin, David J. Muradian, Samad Javid
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Patent number: 11168193Abstract: Reaction mixtures, foams prepared from the reaction mixtures, articles containing the foams, and methods of making the foams are provided. The polymeric material in the foam is formed from a polymerizable composition that includes a di(meth)acrylate oligomer and a monomer having a single ethylenically unsaturated group. The foams are highly filled (e.g., at least 60 volume percent of the foam is the filler) and can be thermally conductive. Although the foams contain a large amount of filler, the foams can be compressed at least 40 volume percent with an applied pressure of 50 pounds per square inch (345 kiloPascals).Type: GrantFiled: July 23, 2019Date of Patent: November 9, 2021Assignee: 3M Innovative Properties CompanyInventors: Audrey S. Forticaux, Joshua M. Fishman, Caitlin E. Meree, Ying Lin, Qin Lin, Carla S. Thomas, Duane D. Fansler, Jimmie R. Baran, Jr.
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Publication number: 20210253816Abstract: Reaction mixtures, foams prepared from the reaction mixtures, articles containing the foams, and methods of making the foams are provided. The polymeric material in the foam is formed from a polymerizable composition that includes a di(meth)acrylate oligomer and a monomer having a single ethylenically unsaturated group. The foams are highly filled (e.g., at least 60 volume percent of the foam is the filler) and can be thermally conductive. Although the foams contain a large amount of filler, the foams can be compressed at least 40 volume percent with an applied pressure of 50 pounds per square inch (345 kiloPascals).Type: ApplicationFiled: July 23, 2019Publication date: August 19, 2021Inventors: Audrey S. Forticaux, Joshua M. Fishman, Caitlin E. Meree, Ying Lin, Qin Lin, Carla S. Thomas, Duane D. Fansler, Jimmie R. Baran, Jr.
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Patent number: 10669211Abstract: Articles and methods of making and using the articles are provided. The articles include inorganic agglomerates having an average dimension in a range from about 50 microns to about 2 mm. The porous agglomerates each include a network of carbon or silica, and metal oxide particles embedded in the network. Some agglomerates are capable of lowering a resonant frequency of an acoustic device when the resonant frequency is in a range from about 50 Hz to about 1500 Hz.Type: GrantFiled: December 22, 2016Date of Patent: June 2, 2020Assignee: 3M INNOVATIVE PROPERTIES COMPNAYInventors: Fabian Stolzenburg, Qin Lin, Noah O. Shanti, Marc D. Radcliffe, Ronald W. Gerdes
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Patent number: 10427032Abstract: A game box for storing game properties and for single-player or two-player game, comprises a first box body, comprising a first base and a first building block base, the first base is provided with a first holding space, the first building block base covers the top of the first base, both ends of rear side are pin connected to both ends of rear side of the first base; an inserting holder, arranged at one end of the first box body, and there is a slot in the top surface of the inserting holder; at least one card, which can be inserted into the slot, and a pattern is printed on the surface of the card; and a first building block set, which can be laid in the locating recess holes of the first building block base.Type: GrantFiled: November 1, 2018Date of Patent: October 1, 2019Assignee: Lonpos Braintelligent Co., Ltd.Inventor: Yu-Qin Lin
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Publication number: 20190016643Abstract: Articles and methods of making and using the articles are provided. The articles include inorganic agglomerates having an average dimension in a range from about 50 microns to about 2 mm. The porous agglomerates each include a network of carbon or silica, and metal oxide particles embedded in the network. Some agglomerates are capable of lowering a resonant frequency of an acoustic device when the resonant frequency is in a range from about 50 Hz to about 1500 Hz.Type: ApplicationFiled: December 22, 2016Publication date: January 17, 2019Inventors: Fabian Stolzenburg, Qin Lin, Noah O. Shanti, Marc D. Radcliffe, Ronald W. Gerdes
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Patent number: 9960038Abstract: Methods of forming microelectronic structure are provided. The methods comprise the formation of T-shaped structures using a controlled undercutting process, and the deposition of a selectively etchable composition into the undercut areas of the T-shaped structures. The T-shaped structures are subsequently removed to yield extremely small undercut-formed features that conform to the width and optionally the height of the undercut areas of the T-shaped structures. These methods can be combined with other conventional patterning methods to create structures having extremely small feature sizes regardless of the wavelength of light used for patterning.Type: GrantFiled: December 22, 2011Date of Patent: May 1, 2018Assignee: Brewer Science, Inc.Inventors: Carlton Ashley Washburn, James E. Lamb, III, Nickolas L. Brakensiek, Qin Lin, Yubao Wang, Vandana Krishnamurthy, Claudia Scott
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Patent number: 9788795Abstract: Provided is a method for compensating for tissue motion during magnetic resonance (MR) imaging, and an apparatus for use thereof. The method includes acquiring a plurality of short-time MR scan images; selecting a reference scan image from the acquired plurality of short-time MR scan images; defining a set of transformation images based on the acquired plurality of short-time MR scan images other than the selected reference scan image; registering the reference scan image and the defined set of transformation images; calculating an average of aligned, registered images of the defined set of transformation images; and generating a motion-corrected image based on the calculated average.Type: GrantFiled: June 6, 2014Date of Patent: October 17, 2017Assignee: The Research Foundation for The State University of New YorkInventors: Jerome Zhengrong Liang, Qin Lin
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Patent number: 9640396Abstract: Novel double- and triple-patterning methods are provided. The methods involve applying a shrinkable composition to a patterned template structure (e.g., a structure having lines) and heating the composition. The shrinkable composition is selected to possess properties that will cause it to shrink during heating, thus forming a conformal layer over the patterned template structure. The layer is then etched to leave behind pre-spacer structures, which comprise the features from the pattern with remnants of the shrinkable composition adjacent the feature sidewalls. The features are removed, leaving behind a doubled pattern. In an alternative embodiment, an extra etch step can be carried out prior to formation of the features on the template structure, thus allowing the pattern to be tripled rather than doubled.Type: GrantFiled: January 5, 2010Date of Patent: May 2, 2017Assignee: Brewer Science Inc.Inventors: Qin Lin, Rama Puligadda, James Claypool, Douglas J. Guerrero, Brian Smith
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Publication number: 20160066856Abstract: Provided is a method for compensating for tissue motion during magnetic resonance (MR) imaging, and an apparatus for use thereof. The method includes acquiring a plurality of short-time MR scan images; selecting a reference scan image from the acquired plurality of short-time MR scan images; defining a set of transformation images based on the acquired plurality of short-time MR scan images other than the selected reference scan image; registering the reference scan image and the defined set of transformation images; calculating an average of aligned, registered images of the defined set of transformation images; and generating a motion-corrected image based on the calculated average.Type: ApplicationFiled: June 6, 2014Publication date: March 10, 2016Inventors: Jerome Zhengrong LIANG, Qin LIN
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Patent number: RE46841Abstract: The invention described herein is directed towards spin-on carbon materials comprising polyamic acid compositions and a crosslinker in a solvent system. The materials are useful in trilayer photolithography processes. Films made with the inventive compositions are not soluble in solvents commonly used in lithographic materials, such as, but not limited to PGME, PGMEA, and cyclohexanone. However, the films can be dissolved in developers commonly used in photolithography. In one embodiment, the films can be heated at high temperatures to improve the thermal stability for high temperature processing. Regardless of the embodiment, the material can be applied to a flat/planar or patterned surface. Advantageously, the material exhibits a wiggling resistance during pattern transfer to silicon substrate using fluorocarbon etch.Type: GrantFiled: November 23, 2016Date of Patent: May 15, 2018Assignee: Brewer Science, Inc.Inventors: Vandana Krishnamurthy, Daniel M. Sullivan, Yubao Wang, Qin Lin, Sean Simmons