Abstract: The present invention discloses an acoustic module waterproof protection mechanism, including an acoustic module arranged in a housing, an acoustic port provided on an outer wall of the housing and communicating with the acoustic module, a waterproof sound-permeable membrane arranged on an inner wall of the housing and covering the acoustic port, the an acoustic module waterproof protection mechanism further includes a waterproof valve assembly embedded in a hole wall of the acoustic port in a stretchable manner, which is used to stretch into the acoustic port to block the acoustic port when an external water pressure is greater than an air pressure in the housing.

Abstract: A model file management method includes that a terminal device receives a storage address of a target model file package from a server and the terminal device obtains the target model file package based on the storage address of the target model file package, where the target model file package is based on a parameter of a model file package locally stored in the terminal device and a parameter of a model file package managed by the server. In an artificial intelligence (AI) field, an application may implement a specific function by using an AI model file. An application is decoupled from an AI model file such that the terminal device performs centralized management on a general model file.

Abstract: An identity certificate may be issued to a blockchain node. The issuance may include issuing a first identity certificate to a first terminal and receiving a second identity certificate issuance request that is from the first terminal. A second identity certificate may be issued to the first terminal, and a third identity certificate issuance request is received from the second terminal. A third identity certificate is issued to the second terminal, so that the second terminal forwards the third identity certificate to the third terminal.

Abstract: The present invention relates to the field of pharmaceutical and chemical engineering, and specifically relates to a weakly acidic microenvironment-sensitive aptamer for tumors, a triptolide conjugate. The conjugate is formed by conjugation between the 14-position hydroxyl group of triptolide and the aptamer via an acetal ester linking bond, which is an acid-sensitive linking bond with a cleavage condition of (pH=3.5-6.5), which is much less pH-sensitive and is more likely to cleave under the tumor microenvironment. Based on the characteristics of the aptamer targeting the highly expressed proteins on the membrane surface of tumor cells, the conjugate delivered triptolide targeted to tumor cells and mediated endocytosis to reach the lysosome; based on the characteristics of the acidic environment of lysosomes, the acetal ester linking bond released intact triptolide in the lysosomal acidic environment, targeting and killing of tumor cells.

Abstract: Described herein are T cells engineered to express a chimeric antigen receptor (CAR), such as an anti-mesothelin CAR alone or in combination with a follicle-stimulating hormone receptor (FSHR) binding domain and/or a dominant negative transforming growth factor-? receptor II (dnTGF?RII) for the treatment of diseases associated with mesothelin expression. Also described are T cells engineered to express a modified T cell receptor (TCR).

Abstract: A flexible probe for microLED defect detection includes: a flexible base and a flexible circuit film layer. The flexible base includes a flexible substrate and flexible protrusions located on the flexible substrate. A circuit for illuminating a microLED to be detected is provided inside the flexible circuit film layer. The flexible circuit film layer is attached to a surface on a side of the flexible base on which the flexible protrusions are provided, at least a portion of the circuit of the flexible circuit film layer is located on the flexible protrusions, and when the flexible probe for MicroLED defect detection is placed on the MicroLED, the circuit on the flexible protrusions abuts against pins of the MicroLED to be detected and is electrically connected to the pins.

Abstract: The present disclosure relates to a method and apparatus for interacting with an application program, and an electronic device. The method includes: playing back multimedia content of a target object; and displaying, in a playback page for the multimedia content, an interaction component of the target object. The interactive component comprises: an integrated interactive card and action button. The interactive card is used for describing introductory content of the target object. The introductory content of the target object comprises: the icon of the target object, first basic information of the target object, and extension information of the target object. The action button is used for providing an entry to an interactive page of the target object.

Abstract: The present disclosure provides a method and device for intelligent control of heating furnace combustion based on a big data cloud platform, which relates to the technical field of artificial intelligence control. The method includes: construction of big data cloud platform based on production and operation parameters of the heating furnace; identification of key factors in the production process of the heating furnace by using big data mining technology; independent deployment of traditional heating furnace combustion control systems based on the mechanism model; and integration of cloud platform big data expert knowledge base and the heating furnace combustion intelligent control system.

Abstract: The present disclosure provides a non-contact fatigue detection system and method based on rPPG. The system and method adopt multi-thread synchronous communication for real-time acquisition and processing of rPPG signal, enabling fatigue status detection. In this setup, the first thread handles real-time rPPG data capture, storage and concatenation, while the second thread conducts real-time analysis and fatigue detection of rPPG data. Through a combination of skin detection and LUV color space conversion, rPPG raw signal extraction is achieved, effectively eliminating interference from internal and external environmental facial noise; Subsequently, an adaptive multi-stage filtering process enhances the signal-to-noise ratio, and a multi-dimensional fusion CNN model ensures accurate detection of respiration and heart rate.

Abstract: Disclosed herein are ethylene-based polymers generally characterized by a melt index of less than 1 g/10 min, a density from 0.93 to 0.965 g/cm3, a CY-a parameter at 190° C. of less than 0.2, an average number of short chain branches per 1000 total carbon atoms of the polymer in a molecular weight range of 400,000 to 600,000 g/mol that is greater than that in a molecular weight range of 40,000 to 60,000 g/mol, and an average number of long chain branches per 1000 total carbon atoms of the polymer in a molecular weight range of 400,000 to 600,000 g/mol that is greater than that in a molecular weight range of 4,000,000 to 6,000,000 g/mol.

Abstract: A preparation method of a Mn-MOF-based cold-adapted nanozyme and a preparation method thereof. The method includes: preparing a Mn(CH3COO)3·2H2O solution by fully dissolving a manganese-containing precursor Mn(CH3COO)3·2H2O in a mixed solution of an alcohol and distilled water; wherein the alcohol is ethanol or methanol; preparing a benzenetricarboxylic acid solution by fully dissolving benzenetricarboxylic acid solid in the mixed solution of the alcohol and distilled water; reacting the Mn(CH3COO)3·2H2O solution with the benzenetricarboxylic acid solution sufficiently using co-precipitation; and centrifuging and removing a supernatant to obtain the MnBTC, where the MnBTC is nano-metal-organic framework (nano-MOF) with a particle size of less than 10 nm.

Abstract: Fluorided silica-coated alumina activator-supports have a bulk density from 0.15 to g/mL, a total pore volume from 0.85 to 2 mL/g, a BET surface area from 200 to 500 m2/g, an average pore diameter from 10 to 25 nm, and from 80 to 99% of pore volume in pores with diameters of greater than 6 nm. Methods of making the fluorided silica-coated alumina activator-supports and using the fluorided silica-coated aluminas in catalyst compositions and olefin polymerization processes also are described. Representative ethylene-based polymers produced using the compositions and processes have a melt index of 0.1 to 10 g/10 min and a density of 0.91 to 0.96 g/cm3, and contain from 70 to 270 ppm solid oxide and from 2 to 18 ppm fluorine.

Abstract: The present invention provides a vertical feeding and wafer inserting integrated machine, comprising a rack and a silicon wafer transfer device provided on the rack; a carrying-transporting water tank for carrying and transporting silicon wafers is provided on one end of the rack; the rack is further provided with a feeding unit for conveying the silicon wafers in the carrying-transporting water tank to a silicon wafer transfer belt a wafer inserting unit for inserting the silicon wafers into wafer baskets is provided on one end, away from the feeding unit, of the silicon wafer transfer device, and a wafer basket arraying mechanism is provided on the other end of the wafer inserting unit; and a washing manipulator for transferring grouped wafer baskets to a washing procedure is further correspondingly provided on the rack.

Abstract: Provided herein, in certain aspects, are antibodies that bind to PSMA, as well as recombinant cells containing the vectors, and compositions comprising the antibodies. Also provided herein, in certain aspects, are multispecific antibodies that bind to PSMA and CD3, as well as recombinant cells containing the vectors, and compositions comprising the antibodies. Methods of making and using the antibodies are also provided.

Abstract: A system and method to generate flood inundation maps in near real time. The system includes a plurality of computer processing modules: a flood trigger system, a SAR data query system, and a RAPID kernel algorithm system, running in real time, to identify the potential flood zones, query SAR data, and finally compute the inundation maps, respectively. As disclosed herein, the RAPID kernel algorithm is extended to a fully automated flood mapping system that requires no human interference from the initial flood events discovery to the final flood map production.

Abstract: The disclosure claims a method of stimulating a conditional quantum master equation in a quantum transport process by a recurrent neural network, comprising the following steps of: establishing a recurrent neural network which is a long short term memory network (LSTM), wherein the LSTM comprises TLSTM cells arranged in chronological order, and each LSTM cell has an input value xt and an output value ht, and there is a parameter (W, b) in the LSTM cell; replacing the input value xt with a shot noise spectrum S(?) of the current obtained according to the conditional quantum master equation; replacing the output value ht with a trace of density matrices in the conditional quantum master equation; and replacing the parameter (W, b) with a connection between density matrices in the conditional quantum master equation at imminent moments.

Abstract: Methods for preparing a metallocene-based catalyst composition that can impact the long chain branching of ethylene homopolymers and copolymers produced using the catalyst composition are described. The catalyst composition can be prepared by contacting a metallocene compound, a hydrocarbon solvent, and a first organoaluminum compound for a first period of time to form a metallocene solution, and then contacting the metallocene solution with an activator-support and a second organoaluminum compound for a second period of time to form the catalyst composition.

Abstract: A blockchain network includes a service sub-network, a consensus sub-network, and a routing layer configured to isolate the service sub-network from the consensus sub-network. A data processing method in the blockchain network includes: receiving a data processing request transmitted by a service node in the service sub-network; performing identity verification on the service node according to the data processing request; obtaining a running load of each consensus node in the consensus sub-network when the verification succeeds; determining, from the consensus sub-network according to the running load, a target consensus node configured to process the data processing request; and forwarding the data processing request to the target consensus node, and performing corresponding data processing on the data processing request by using the target consensus node.

Abstract: A power module can include a casing mounted to a baseplate that contains a substrate with circuitry. The circuitry can include pins for coupling signals to/from the circuitry. These pins can extend through a cover portion of the casing so that an electronic substrate, such as a printed circuit board (PCB) can be press-fit onto the pins. When press-fit, the electronic substrate is supported and positioned by support pillars that extend from the base plate to above the cover portion of the casing. If the pins and the support pillars have different coefficients of thermal expansion, damage to connection points between the pins and the circuitry may occur. Here, a power module is disclosed that has thermally matched pins and support pillars so that when the system is thermally cycled over a range of temperatures, the connection points are not damaged by forces induced by thermal expansion.

Abstract: This disclosure provides new methods for the design and development of ethylene polymerization catalysts, including Group 4 metallocene catalysts such as zirconocenes, which are based on an improved ability to adjust co-monomer incorporation into the polymer. Computational analyses with and without dispersion corrections revealed that designing catalyst scaffolds which induce stabilizing non-covalent dispersion type interactions with incoming ?-olefin co-monomers can be used to modulate co-monomer selectivity into the polyethylene chain. Demonstrated herein is a lack of correlation of computed ??G‡ values against experimental ??G‡ values when the dispersion correction (D3BJ) was disabled, and B3LYP was used in the absence of Grimme's D3 dispersion and Becke-Johnson (BJ) dampening, but a correlation of computed against experimental ??G‡ with B3LYP+D3BJ, which are used to design new catalyst scaffolds.