Patents by Inventor Rainer Hoffmann

Rainer Hoffmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6617452
    Abstract: The subject matter of the present invention concerns a process for the isolation of the alkaloid galanthamine; the galanthamine itself which has been produced according to this process; the use of the galanthamine thus produced in galenic preparations; and the galanthamine thus produced for treating narrow-angle glaucoma, Alzheimer's disease, as well as alcohol and nicotine dependence.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: September 9, 2003
    Assignee: LTS Lohmann Therapie-Systeme AG
    Inventors: Thomas Hille, Hans-Rainer Hoffmann, Mirko Kreh, Rudolf Matusch
  • Publication number: 20030159477
    Abstract: The invention relates to a bar lock for a locking system that is used, in particular, in metal cabinet doors. Said locking system comprises a lock body (10) and a pinion (18), which is mounted therein and which is provided for actuating the lock bars (12) reaching through the lock body (10). The invention is characterized in that two pinions (18), which are connected to one another with positive fit, are placed inside the one-piece lock body (10), and the engaging openings, which are formed on the lock bars (12) and provided for the teeth (19) of the pinion (18), are provided in the form of laterally open denticulations (29) and as perforations (30).
    Type: Application
    Filed: March 6, 2003
    Publication date: August 28, 2003
    Inventors: Rainer Hoffmann, Manfred Sauerland
  • Patent number: 6599511
    Abstract: Desoxypeganine and its pharmaceutically acceptable acid addition salts can be used in the treatment of drug addiction or drug dependence. Said substances are administered preferably in a continuos and controlled manner. The pharmaceutical administration form enables controlled release, e.g. for oral transdermal or another route of parenteral administration.
    Type: Grant
    Filed: October 17, 2001
    Date of Patent: July 29, 2003
    Assignees: LTS Lohmann Therapie-Systeme AG, HF Aezneimittelforschung GmbH
    Inventors: Bodo Asmussen, Thomas Hille, Hans-Rainer Hoffmann, Klaus Opitz
  • Patent number: 6573376
    Abstract: The subject matter of the present invention concerns a process for the isolation of the alkaloid galanthamine; the galanthamine itself which has been produced according to this process; the use of the galanthamine thus produced in galenic preparations; and the galanthamine thus produced for treating narrow-angle glaucoma, Alzheimer's disease, as well as alcohol and nicotine dependence.
    Type: Grant
    Filed: November 9, 2001
    Date of Patent: June 3, 2003
    Assignee: LTS Lohmann Therapie-Systeme AG
    Inventors: Thomas Hille, Hans-Rainer Hoffmann, Mirko Kreh, Rudolf Matusch
  • Patent number: 6548510
    Abstract: Desoxypeganine and its pharmaceutically acceptable acid addition salts are useful in treating nicotine dependence.
    Type: Grant
    Filed: July 19, 2001
    Date of Patent: April 15, 2003
    Assignees: LTS Lohmann Therapie Systeme AG, HF Arzneimittelforschung GmbH
    Inventors: Bodo Asmussen, Thomas Hille, Hans-Rainer Hoffmann, Klaus Opitz
  • Publication number: 20030012831
    Abstract: The subject matter of the present invention concerns a process for the isolation of the alkaloid galanthamine; the galanthamine itself which has been produced according to this process; the use of the galanthamine thus produced in galenic preparations; and the galanthamine thus produced for treating narrow-angle glaucoma, Alzheimer's disease, as well as alcohol and nicotine dependence.
    Type: Application
    Filed: September 12, 2002
    Publication date: January 16, 2003
    Inventors: Thomas Hille, Hans-Rainer Hoffmann, Mirko Kreh, Rudolf Matusch
  • Patent number: 6439015
    Abstract: A casement closure device for a door is provided, and includes a housing adapted to be fixed to a door leaf or cabinet body. A key-operated lock cylinder is removably disposed in a channel of the housing. A locking tongue is held against the housing and is rotatable between an unlocking and a locking position. The lock cylinder is uncoupled from the locking tongue and is locked in the housing when a key is withdrawn from the lock cylinder. When a key is inserted and moved to the unlocking position, the lock cylinder is removable. The locking tongue is provided with an actuation opening adapted to positively engage an actuating unit insertable in the housing channel when the lock cylinder is removed from the housing.
    Type: Grant
    Filed: December 14, 2000
    Date of Patent: August 27, 2002
    Assignee: EMKA Beschlagteile GmbH & Co. KG
    Inventors: Manfred Sauerland, Rainer Hoffmann
  • Patent number: 6436937
    Abstract: The invention relates to a device and method for the treatment of Alzheimer's dementia with desoxypeganine and/or a pharmaceutically acceptable acid addition salt of desoxypeganine.
    Type: Grant
    Filed: August 16, 2001
    Date of Patent: August 20, 2002
    Assignee: LTS Lohman-Therapie Systeme AG
    Inventors: Bodo Asmussen, Thomas Hille, Hans-Rainer Hoffmann, Klaus Opitz
  • Patent number: 6354638
    Abstract: A bar-type closure for a door is provided. An actuating device is disposed on the outer surface of the door leaf and is rotatable between an opened and a closed position, with the rotational movement of the actuating device being convertible to longitudinal displacement of at least one locking rod that is guided parallel to the pivot axis of the door on the inner side of the door leaf thereof. The actuating device is provided with a hand lever that is pivotable outwardly about a hinge line axis oriented parallel to the pivot axis of the door and to the direction of displacement of the locking rod. The enlargement of the spacing between the hand lever and the door leaf, when the hand lever pivots, is converted into displacement of the locking rod into its release position by means of a Z-shaped drive lever that is disposed between the door leaf and the hand lever. One end of the drive lever is non-displaceably mounted in a first journal on an inner surface of the hand lever that faces the door leaf.
    Type: Grant
    Filed: March 24, 2000
    Date of Patent: March 12, 2002
    Assignee: EMKA Beschlagteile GmbH & Co KG
    Inventor: Rainer Hoffmann
  • Publication number: 20020028802
    Abstract: The subject matter of the present invention concerns a process for the isolation of the alkaloid galanthamine; the galanthamine itself which has been produced according to this process; the use of the galanthamine thus produced in galenic preparations; and the galanthamine thus produced for treating narrow-angle glaucoma, Alzheimer's disease, as well as alcohol and nicotine dependence.
    Type: Application
    Filed: November 9, 2001
    Publication date: March 7, 2002
    Inventors: Thomas Hille, Hans-Rainer Hoffmann, Mirko Kreh, Rudolf Matusch
  • Patent number: 6335328
    Abstract: The subject matter of the present invention concerns a process for the isolation of the alkaloid galanthamine; the galanthamine itself which has been produced according to this process; the use of the galanthamine thus produced in galenic preparations; and the galanthamine thus produced for treating narrow-angle glaucoma, Alzheimer's disease, as well as alcohol and nicotine dependence.
    Type: Grant
    Filed: December 21, 2000
    Date of Patent: January 1, 2002
    Assignee: LTS Lohmann Therapie-Systeme GmbH
    Inventors: Thomas Hille, Hans-Rainer Hoffmann, Mirko Kreh, Rudolf Matusch
  • Patent number: 6290989
    Abstract: The present invention describes a device for the controlled release of active compounds in the gastrointestinal tract with delayed pyloric passage, having a component expandable on contact with gastric juice, which is surrounded by a polymer covering which is permeable to gastric juice and active compounds. The device contains at least one active compound which is present in a multiparticulate preparation which releases the active compound into the gastric juice with a delay. Compared with conventional pharmaceutical forms with delayed pyloric passage, the release of active compound from a device according to the invention can be better controlled; likewise the device can be easily rolled or folded and can be introduced into capsules without problems.
    Type: Grant
    Filed: August 31, 1999
    Date of Patent: September 18, 2001
    Assignee: LTS Lohmann Therapie-Systeme AG
    Inventors: Bodo Asmussen, Karsten Cremer, Hans-Rainer Hoffmann, Karin Ludwig, Michael Roreger
  • Publication number: 20010001100
    Abstract: The subject matter of the present invention concerns a process for the isolation of the alkaloid galanthamine; the galanthamine itself which has been produced according to this process; the use of the galanthamine thus produced in galenic preparations; and the galanthamine thus produced for treating narrow-angle glaucoma, Alzheimer's disease, as well as alcohol and nicotine dependence.
    Type: Application
    Filed: December 21, 2000
    Publication date: May 10, 2001
    Inventors: Thomas Hille, Hans-Rainer Hoffmann, Mirko Kreh, Rudolf Matusch
  • Patent number: 6194404
    Abstract: The subject matter of the present invention concerns a process for the isolation of the alkaloid galanthamine; the galanthamine itself which has been produced according to this process; the use of the galanthamine thus produced in galenic preparations; and the galanthamine thus produced for treating narrow-angle glaucoma, Alzheimer's disease, as well as alcohol and nicotine dependence.
    Type: Grant
    Filed: August 7, 1998
    Date of Patent: February 27, 2001
    Assignee: LTS Lohmann Therapie-Systeme GmbH
    Inventors: Thomas Hille, Hans-Rainer Hoffmann, Mirko Kreh, Rudolf Matusch
  • Patent number: 6190689
    Abstract: A device for the release of substances from pressure sensitive hot-melt adhesives with a uniform or non-uniform distribution of said substances is characterized by the fact that the pressure sensitive hot-melt adhesive is hydrophilic and comprises at least one water-soluble, or at least water-swellable, polymer, at least one water-soluble, meltable adhesive resin, as well as substance to be released.
    Type: Grant
    Filed: November 13, 1996
    Date of Patent: February 20, 2001
    Assignee: LTS Lohmann Therapie-Systeme GmbH
    Inventors: Hans-Rainer Hoffmann, Michael Roreger
  • Patent number: 6103253
    Abstract: A sprayable, film-forming active substance preparation for the application to plants is characterized by the fact that films which can be produced thereof are pressure-sensitive adhesive, water-insoluble, and at least partially biodegradable.
    Type: Grant
    Filed: May 23, 1997
    Date of Patent: August 15, 2000
    Assignee: LTS Lohmann Therapie-Systeme, GmbH
    Inventors: Hans-Rainer Hoffmann, Michael Roreger, Malgorzata Kloczko
  • Patent number: 6103251
    Abstract: A process for the administration of a flowable solid, semisolid, or liquid medium exhibiting a controlled release of at least one active substance to plants by means of injection using needle-free, pressure-actuated devices is characterized in that the medium comprises active substance-containing microparticles of a maximum size of 100 .mu.m including the following components:a) 0.5-70%-wt. of at least one active substance,b) 10-70%-wt. of at least one biodegradable polymer,c) up to 20%-wt. of formulation adjuvants.
    Type: Grant
    Filed: September 14, 1998
    Date of Patent: August 15, 2000
    Assignee: LTS Lohmann Therapie-Systeme GmbH
    Inventors: Hans-Rainer Hoffmann, Malgorzata Kloczko, Michael Roreger
  • Patent number: 5922670
    Abstract: Dimer alcohol bis-sulfates, trimer alcohol tris-sulfates and ether sulfates thereof are prepared by reacting dimer alcohols, trimer alcohols, or alkylene oxide adducts thereof with a sulfating agent, and then neutralizing the reaction product with an aqueous base material.
    Type: Grant
    Filed: October 1, 1997
    Date of Patent: July 13, 1999
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Georg Knuebel, Alfred Westfechtel, Gerhard Hermanns, Rainer Hoffmann, Hans-Christian Raths
  • Patent number: 5914295
    Abstract: Implantable, partially biodegradable, polymer-containing molded articles for the administration of active substances to plants are characterized by the fact that they comprise at least one hydrophobic polymer.
    Type: Grant
    Filed: June 11, 1997
    Date of Patent: June 22, 1999
    Assignee: LTS Lohmann Therapie-Systeme GmbH
    Inventors: Hans-Rainer Hoffmann, Malgorzata Kloczko, Michael Roreger
  • Patent number: 5895660
    Abstract: A drug for the release of active substances to the skin, which has an increased deuterium portion as compared to the natural isotope distribution.
    Type: Grant
    Filed: August 15, 1996
    Date of Patent: April 20, 1999
    Assignee: LTS Lohmann Therapie-Systeme GmbH
    Inventors: Hans-Rainer Hoffmann, Thomas Hille, Andreas Koch, Rudolf Matusch