Abstract: An underpinning pile assembly for supporting a structure upon the earth has a plurality of pile segments, a cable extending through a continuous passageway of the plurality of pile segments, and an anchor assembly positioned at the top of the plurality of pile segments. Each of the plurality of pile segments is stacked one upon another. The cable has a lower end affixed to one of the plurality of pile segments. The anchor has an opening that receives a portion of the cable therein so as to fix a position of an upper end of the cable. The anchor assembly has at least one column extending upwardly from an upper surface thereof. An adjustable support is affixed to the column and has a surface opposite the column that is adapted to support the structure thereon.

Abstract: An underpinning pile assembly for supporting a structure upon the earth has a plurality of pile segments, a cable extending through a continuous passageway of the plurality of pile segments, and an anchor assembly positioned at the top of the plurality of pile segments. Each of the plurality of pile segments is stacked one upon another. The cable has a lower end affixed to one of the plurality of pile segments. The anchor has an opening that receives a portion of the cable therein so as to fix a position of an upper end of the cable. The anchor assembly has at least one column extending upwardly from an upper surface thereof. An adjustable support is affixed to the column and has a surface opposite the column that is adapted to support the structure thereon.

Abstract: A data recording and annotation system includes data recording device for generating a data record. After the data recording device receives a request to review the one or more data records, the data recorder provides the one or more data records to the requester. After the data recorder receives an approval or annotation made about the data record, the data recorder generates a revised data record including information from the data record and from the approval or annotation. Then the revised data record is stored on the data recording device. The data records may be accessed at either the data generating device itself, or through a remote connection.

Abstract: An actuation valve for a pest control device, the actuation valve including a primary valve seat; a secondary valve seat; a valve seal, a recess between the primary and secondary valve seats, and an actuation arm. The actuation valve includes primary and secondary valves. The recess is located between primary and secondary valve seats to receive gas from the primary valve and promote displacement of the valve seal from the secondary valve seat. Also provided are an actuation valve with magnetic elements, an actuation valve with a trigger, a pest control device, a piston assembly for a pest control device, and a pest control assembly.

Abstract: Provided herein are compositions and methods for improving outcome in stem cell transplantation. In particular, provided herein are compositions and methods for improving efficacy and reducing graft versus host disease in allogenic cell transplantation.

Abstract: An animal trap includes: a bait, a support, and an elastic band, wherein in a set state the support supports the elastic band in an expanded state, and wherein removal, consumption or destruction of the bait by an animal: causes the elastic band to contract around the animal to kill the animal; or causes the elastic band to drive a kill mechanism to kill the animal. Animal traps may be formed substantially or entirely of biodegradable materials. Animal traps may be adapted for aerial distribution. A trap dispenser may dispense traps as they are triggered.

Abstract: An animal trap includes: a bait, a support, and an elastic band, wherein in a set state the support supports the elastic band in an expanded state, and wherein removal, consumption or destruction of the bait by an animal: causes the elastic band to contract around the animal to kill the animal; or causes the elastic band to drive a kill mechanism to kill the animal. Animal traps may be formed substantially or entirely of biodegradable materials. Animal traps may be adapted for aerial distribution. A trap dispenser may dispense traps as they are triggered.

Abstract: The chronic use of ?-adrenergic inverse agonists such as nadolol, carvedilol, and ICI-118,551 provides an improved method for the treatment of mucus hypersecretion in subjects with such mucus hypersecretion or at risk of developing mucus hypersecretion, especially in subjects attempting smoking cessation. One aspect of a method according to the present invention is a method of preventing or controlling mucus hypersecretion in the respiratory tract comprising administering a therapeutically effective quantity of a ?-adrenergic inverse agonist to a subject with mucus hypersecretion or at risk of mucus hypersecretion. Another aspect of a method according to the present invention is a method of treating or preventing a disease or condition characterized by mucus hypersecretion comprising administering a therapeutically effective quantity of a ?-adrenergic inverse agonist to a subject with such a disease or condition or at risk of contracting such a disease or condition.

Abstract: The chronic use of p-adrenergic inverse agonists such as nadolol, carvedilol, and ICI-118,551 provides an improved method for the treatment of mucus hypersecretion in subjects with such mucus hypersecretion. One aspect of a method according to the present invention is a method of preventing or controlling mucus hypersecretion in the respiratory tract comprising administering a therapeutically effective quantity of a p-adrenergic inverse agonist to a subject with mucus hypersecretion or at risk of mucus hypersecretion. The invention further encompasses pharmaceutical compositions comprising the p-adrenergic inverse agonist and the additional compound.

Abstract: Provided herein is a pharmaceutical composition combination which comprises (a) a corticosteroid and (b) b-adrenergic receptor antagonist characterised in that active ingredients (a) and (b) form part of a single composition. Further provided is a method of treating a human or animal patient suffering from or susceptible to a respiratory disease or condition, said method comprises simultaneously, concurrently, separately or sequentially administering to the patient an effective amount of a b-adrenergic receptor antagonist and a corticosteroid.

Abstract: An animal trap may include a source of compressed gas; a trigger mechanism configured to be actuated by an animal, and a kill mechanism powered by compressed gas. The trap may include two or more trigger valves connected in series. At least one trigger valve may include an opening, a valve seat surrounding the opening, a valve member having a sealing surface, and an O-ring arranged to seal between the sealing surface and the valve seat. One or more flow paths may allow gas to flow along at least part of an internal periphery of the O-ring. The trigger may include a trigger rod extending in a rest position from a mount at or near a first end thereof. The trigger rod may be mounted for pivoting movement about the mount, and may have two rotational degrees of freedom. Pivoting movement of the trigger rod in any direction away from the rest position may result in actuation of the trigger.

Abstract: An animal trap may include a source of compressed gas; a trigger mechanism configured to be actuated by an animal, and a kill mechanism powered by compressed gas. The trap may include two or more trigger valves connected in series. At least one trigger valve may include an opening, a valve seat surrounding the opening, a valve member having a sealing surface, and an O-ring arranged to seal between the sealing surface and the valve seat. One or more flow paths may allow gas to flow along at least part of an internal periphery of the O-ring. The trigger may include a trigger rod extending in a rest position from a mount at or near a first end thereof. The trigger rod may be mounted for pivoting movement about the mount, and may have two rotational degrees of freedom. Pivoting movement of the trigger rod in any direction away from the rest position may result in actuation of the trigger.

Abstract: The use of ?-adrenergic inverse agonists provides a new and highly efficient way of treating a number of pulmonary airway diseases, including asthma, emphysema, and chronic obstructive pulmonary diseases. In general, such a method comprises administering a therapeutically effective amount of a ?-adrenergic inverse agonist to the subject to treat the pulmonary airway disease. Particularly preferred inverse agonists include nadolol and carvedilol.

Abstract: An animal trap is powered by compressed gas and includes a trigger mechanism and kill mechanism. The trap is preferably self-resetting. A variety of sources of compressed gas may be used, and different kill mechanisms may also be used. The trap is particularly suited to applications where low-maintenance traps are required, because it uses a simple, reliable mechanism which can kill a number of animals over a long period of time without requiring maintenance or manual resetting.

Abstract: An animal trap includes: a bait, a support, and an elastic band, wherein in a set state the support supports the elastic band in an expanded state, and wherein removal, consumption or destruction of the bait by an animal: causes the elastic band to contract around the animal to kill the animal; or causes the elastic band to drive a kill mechanism to kill the animal. Animal traps may be formed substantially or entirely of biodegradable materials. Animal traps may be adapted for aerial distribution. A trap dispenser may dispense traps as they are triggered.

Abstract: An animal trap may include a source of compressed gas; a trigger mechanism configured to be actuated by an animal, and a kill mechanism powered by compressed gas. The trap may include two or more trigger valves connected in series. At least one trigger valve may include an opening, a valve seat surrounding the opening, a valve member having a sealing surface, and an O-ring arranged to seal between the sealing surface and the valve seat. One or more flow paths may allow gas to flow along at least part of an internal periphery of the O-ring. The trigger may include a trigger rod extending in a rest position from a mount at or near a first end thereof. The trigger rod may be mounted for pivoting movement about the mount, and may have two rotational degrees of freedom. Pivoting movement of the trigger rod in any direction away from the rest position may result in actuation of the trigger.

Abstract: The chronic use of p-adrenergic inverse agonists such as nadolol, carvedilol, and ICI-118,551 provides an improved method for the treatment of mucus hypersecretion in subjects with such mucus hypersecretion. One aspect of a method according to the present invention is a method of preventing or controlling mucus hypersecretion in the respiratory tract comprising administering a therapeutically effective quantity of a p-adrenergic inverse agonist to a subject with mucus hypersecretion or at risk of mucus hypersecretion. The invention further encompasses pharmaceutical compositions comprising the p-adrenergic inverse agonist and the additional compound.

Abstract: Provided herein is a pharmaceutical composition combination which comprises (a) a corticosteroid and (b) b-adrenergic receptor antagonist characterised in that active ingredients (a) and (b) form part of a single composition. Further provided is a method of treating a human or animal patient suffering from or susceptible to a respiratory disease or condition, said method comprises simultaneously, concurrently, separately or sequentially administering to the patient an effective amount of a b-adrenergic receptor antagonist and a corticosteroid.

Abstract: An animal trap is powered by compressed gas and includes a trigger mechanism and kill mechanism. The trap is preferably self-resetting. A variety of sources of compressed gas may be used, and different kill mechanisms may also be used. The trap is particularly suited to applications where low-maintenance traps are required, because it uses a simple, reliable mechanism which can kill a number of animals over a long period of time without requiring maintenance or manual resetting.

Abstract: A method of transferring information stored in a mobile instrument, the information including a first information file (140) containing metadata and a pointer indicative of a first auxiliary file address; and a first auxiliary file (141) containing image information, the first auxiliary file being located at the first auxiliary file address. The method includes the steps of: storing the metadata in a second information file (140?); storing the image information in a second auxiliary file (142?) at a second auxiliary file address; generating a second pointer indicative of the second auxiliary file address; and storing the second pointer in the second information file. The instrument includes a camera (70); one or more spatial sensors; and an external sensor port (56). Power to the sensors can be controlled asynchronously. Various parsing methods are also described. The instrument includes a marker module configured to superimpose a marker on the image.