Abstract: The present invention provides, among other things, method of treating stroke including a step of administering an angiotensin (1-7) peptide to a subject suffering from a stroke, approximately 24 hours after the stroke. In some embodiments, treatment begins more than 24 hours after the stroke. In some embodiments, administration of an angiotensin (1-7) peptide results in a reduction in the intensity, severity, duration, and/or frequency of at least one symptom or feature of the one or more complications of stroke.

Abstract: The present invention provides, among other things, methods of treating Marfan Syndrome and/or a Marfan-related disorder including administering to a subject suffering from or susceptible to Marfan Syndrome and/or a Marfan-related disorder an angiotensin (1-7) peptide. In some embodiments, the angiotensin (1-7) peptide is administered at an effective dose periodically at an administration interval such that at least one symptom or feature of Marfan Syndrome and/or a Marfan-related disorder is reduced in intensity, severity, duration, or frequency or has delayed in onset.

Abstract: An electronic device may include a communications interface, a user prompting device, a biometric sensor, and a controller. The controller may perform biometric spoof detection with the biometric sensor, and receive a request for human presence verification from a remote device via the communications interface. The controller may also prompt the user for a verification action using the sensor based upon receiving the request, and determine that the user has completed the verification action in response to the prompting and based upon the biometric spoof detection. The controller may further send a response to the remote device via the communications interface and based upon determining that the user has completed the verification action. The controller may send a notification to the remote device that there is a biometric sensor.

Abstract: A fastener including a bolt having an elongated shank having a first end, a second end opposite the first end, and a threaded portion having an external bolt thread, the bolt thread including a bolt pitch. The fastener includes a nut having a first end, a second end opposite the first end of the nut, and an internal nut thread extending between the first and second ends of the nut and adapted to engage threadedly the bolt thread of the bolt. The nut thread includes a nut pitch and a hardness that changes gradationally between the first and second ends of the nut. The bolt pitch of the bolt thread of the bolt is mismatched with the nut pitch of the nut thread of the nut.

Abstract: The present invention provides, among other things, novel peptides and compositions for treating disease.

Abstract: The present invention provides, among other things, methods and compositions for treating or preventing fibrotic diseases, disorders or conditions based on Angiotensin (1-7) polypeptides, and analogs or derivatives thereof. In some embodiments, compositions and methods for treating or preventing pulmonary fibrosis, pulmonary hypertension, chronic obstructive pulmonary disease (COPD), asthma, cystic fibrosis, kidney fibrosis, liver fibrosis, systemic sclerosis, post-surgical adhesions, accelerating wound healing, and reducing or preventing scar formation are provided.

Abstract: The present invention provides, among other things, methods of treating Marfan Syndrome and/or a Marfan-related disorder including administering to a subject suffering from or susceptible to Marfan Syndrome and/or a Marfan-related disorder an angiotensin (1-7) peptide. In some embodiments, the angiotensin (1-7) peptide is administered at an effective dose periodically at an administration interval such that at least one symptom or feature of Marfan Syndrome and/or a Marfan-related disorder is reduced in intensity, severity, duration, or frequency or has delayed in onset.

Abstract: Processing network events generates multiple events from a single network device event. The system includes a network monitoring device for acquiring event data and a processing system for receiving an input event from a network monitoring device on a processing thread, wherein the processing system includes a communications thread generating component for generating multiple communications threads each for transmitting event data to a server database. The communication threads open connections to required server databases and these connections are maintained in an open state while the network monitoring device is running.

Abstract: A catalytic cracking catalyst composition is disclosed that is suitable for reducing the sulfur content of catalytically cracking liquid products, in particularly gasoline products, produced during a catalytic cracking process. Preferably, the catalytic cracking process is a fluidized catalytic cracking (FCC) process. The composition comprises zeolite, zinc and at least one rare earth element having an ionic radius of less than 0.95 ? at a coordination number of 6. Preferably, zinc and the rare earth element are present as cations that have been exchanged on the zeolite. The zeolite is preferably a Y-type zeolite.

Abstract: Method and apparatus for application profiling in a multi-device data storage array. In accordance with various embodiments, a storage array is formed of independent data storage devices that form a fast pool and a slow pool of said devices, such as solid-state drives (SSDs) and hard disc drives (HDDs). A controller is adapted to migrate a distributed data set stored across a first plurality of the devices in the slow pool to a second plurality of said devices in the fast pool. The controller carries out the migration responsive to a hint that a selected application is about to be executed that utilizes the distributed data set, and responsive to a return on investment (ROI) determination that an estimated cost of said migration will be outweighed by an overall improved data transfer capacity of the storage array over a predetermined minimum payback period of time.

Abstract: A method for passing ingress and egress jumbo frames and maximizing the use of frame bursts in a cable modem including, receiving from a client device one or more packets to be transmitted over a communication channel, queuing the one or more packets, determining a maximum size of a burst frame transmitted over the communication channel, adding each of the one or more packets in their entirety to the burst frame until the maximum size of the burst frame is reached, determining whether the burst frame has available space, when space is available, fragmenting a packet of the one or more packets into at least a first and a second fragment packet, wherein the first fragment packet has a size substantially equal to the available space of burst frame, and adding the first fragment packet to the burst frame and transmitting the burst frame during a transmit window.

Abstract: An adjustable mounting assembly for attaching an attachment end of a first beam member to a second beam member. The adjustable mounting assembly includes a first bracket attachable to the first beam member; a second bracket attachable to the second beam member; and a point of attachment where the first and second brackets are attached to each other. The adjustable mounting assembly is configured to allow a position of the first beam member to be adjusted relative to the second beam member.

Abstract: Method and apparatus for managing data in a multi-device data storage array. In accordance with various embodiments, a storage array of independent data storage devices are arranged to form a fast pool and a slow pool of said devices. A controller is adapted to migrate a distributed data set stored across a first plurality of said devices in the slow pool to a second plurality of said devices in the fast pool. The migration is carried out responsive to a return on investment (ROI) determination by the controller that an estimated cost of said migration will be outweighed by an overall improved data transfer capacity of the storage array over a predetermined minimum payback period of time. In some embodiments, the fast pool is formed from a plurality of solid-state drives (SSDs) and the slow pool is formed from a plurality of hard disc drives (HDD).

Abstract: An electronic device may include a communications interface, a user prompting device, a biometric sensor, and a controller. The controller may perform biometric spoof detection with the biometric sensor, and receive a request for human presence verification from a remote device via the communications interface. The controller may also prompt the user for a verification action using the sensor based upon receiving the request, and determine that the user has completed the verification action in response to the prompting and based upon the biometric spoof detection. The controller may further send a response to the remote device via the communications interface and based upon determining that the user has completed the verification action. The controller may send a notification to the remote device that there is a biometric sensor.

Abstract: The present invention provides, among other things, methods and compositions for treating brain conditions. In some embodiments, the methods include administering to a subject suffering from or susceptible to a brain condition an angiotensin (1-7) peptide via either an intravenous or subcutaneous route of administration.

Abstract: A method and a system related to monitoring a safety distance of adjacent vehicles is disclosed. According to one embodiment, a method of a first vehicle includes determining that a second vehicle is in motion in front of the first vehicle when the first vehicle is in motion and calculating a distance between the second vehicle and the first vehicle through a range measurement device of the first vehicle when the first vehicle and the second vehicle are in motion. The method also includes generating an alert at an administrative server when the distance between the second vehicle and the first vehicle is less than a safety distance. The method may include applying a value data (e.g. a weight, length, and/or speed of the first vehicle) at the administrative server to determine when the distance between the second vehicle and the first vehicle is less than the safety distance.

Abstract: The present invention relates to compositions and methods for treatment and/or prevention of diabetes or pre-diabetes. In particular, the invention provides compositions and methods for the treatment and/or prevention of diabetes or pre-diabetes, based on the use of angiotensin-(1-7) peptides, functional equivalents thereof, and/or angiotensin (1-7) agonists.

Abstract: The present invention provides, among other things, methods and compositions for treating brain conditions. In some embodiments, the methods include administering to a subject suffering from or susceptible to a brain condition an angiotensin (1-7) peptide via either an intravenous or subcutaneous route of administration.

Abstract: A method for passing ingress and egress jumbo frames and maximizing the use of frame bursts in a cable modem including, receiving from a client device one or more packets to be transmitted over a communication channel, queuing the one or more packets, determining a maximum size of a burst frame transmitted over the communication channel, adding each of the one or more packets in their entirety to the burst frame until the maximum size of the burst frame is reached, determining whether the burst frame has available space, when space is available, fragmenting a packet of the one or more packets into at least a first and a second fragment packet, wherein the first fragment packet has a size substantially equal to the available space of burst frame, and adding the first fragment packet to the burst frame and transmitting the burst frame during a transmit window.

Abstract: This invention relates to a process of preparing a catalyst from zeolite having a relatively high content of sodium of 18.6 ?g Na2O per zeolite surface area, or greater. The invention comprises adding yttrium compound to the zeolite, either prior to, during, or after its combination with precursors for catalyst matrix. This invention is suitable for preparing zeolite containing fluid cracking catalysts.