Patents by Inventor Richard Franklin

Richard Franklin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL ULTRA STABLE ZEOLITE Y AND METHOD FOR MANUFACTURING THE SAME
    Publication number: 20110224067
    Abstract: This invention comprises USY zeolite prepared by treating a USY zeolite under hydrothermal conditions after forming the USY zeolite from heat treating ammonium exchanged zeolite Y, e g, by calcination. When this invention is used in a FCC catalyst, a significant improvement of activity and selectivity in the fluid catalytic cracking (FCC) performance is observed, compared to FCC catalysts containing conventional USY zeolite. The process used to make the invention is efficient and comprises treating the USY zeolite in an exchange bath under the aforementioned hydrothermal conditions. The surface of the resulting USY zeolite has a molar ratio of alumina to silica that is higher than that seen in the bulk USY zeolite and has a unique structure as viewed by SEM and TEM.
    Type: Application
    Filed: December 17, 2009
    Publication date: September 15, 2011
    Inventors: Richard Franklin Wormsbecher, Wu-Cheng Cheng, Michael Wallace, Wilson Suarez, Yuying Shu
  • MOBILE TOMOGRAPHIC CARGO INSPECTION SYSTEM
    Publication number: 20110186739
    Abstract: Apparatus for scanning large cargo to detect concealed contents include a mobile platform configured to carry and position at least one X-ray or gamma-ray source and at least one detector array at a plurality of positions with respect to a stationary cargo. The detector array may be mounted on a boom moveably affixed to the mobile platform. Multiple measurements of radiation passing through the cargo for various source-detector orientations can be used to compute volumetric images of concealed content within the cargo.
    Type: Application
    Filed: February 4, 2011
    Publication date: August 4, 2011
    Applicant: L-3 Communications Security and Detection Systems Inc.
    Inventors: Andrew D. Foland, Richard Franklin Eilbert, Michael R. Gambini, Nicholas Danvers Penrose Gillett, Ronald S. McNabb, Boris Oreper, David Perticone, Vitaliy Ziskin
  • PRODRUGS OF OPIOIDS AND USES THEREOF
    Publication number: 20110190267
    Abstract: The present invention concerns prodrugs of opioid analgesics and pharmaceutical compositions containing such prodrugs. Methods for providing more consistent pain relief by increasing the bioavailability of the opioid analgesic with the aforementioned prodrugs are provided. The invention also provides for decreasing the adverse GI side effects of opioid analgesics.
    Type: Application
    Filed: December 23, 2010
    Publication date: August 4, 2011
    Applicant: Shire Pharmaceuticals, Inc.
    Inventors: Richard Franklin, Karl Swift, Bernard T. Golding, Robert G. Tyson
  • IMIDAZO [2,1-B] QUINAZOLIN-2-ONE DERIVATIVES AND THEIR USE AS PLATELET ANTI-AGGREGATIVE AGENTS
    Publication number: 20110152298
    Abstract: This invention relates to the discovery of substituted analogues of the selective platelet lowering agent anagrelide with reduced potential for cardiovascular side-effects which should lead to improved patient compliance and safety in the treatment of myeloproliferative diseases. More specifically, the present invention relates to certain imidazoquinazoline derivatives which have the general formula shown below where the substituents have the meanings defined in claim (I) and which have utility as platelet lowering agents in humans. The compounds of the present invention function by inhibiting megakaryocytopoeisis and hence the formation of blood platelets.
    Type: Application
    Filed: May 13, 2009
    Publication date: June 23, 2011
    Applicant: SHIRE LLC
    Inventors: Bernard T. Golding, Richard Franklin, Angus Macleod, Peter Cicala
  • SUBSTITUTED QUINAZOLINES
    Publication number: 20110130413
    Abstract: This invention relates to the discovery of prodrugs of substituted analogues of the selective platelet lowering agent anagrelide which have reduced potential for cardiovascular side-effects and which should therefore lead to improved patient compliance and safety in the treatment of myeloproliferative diseases. More specifically, the present invention relates to prodrugs of certain imidazoquinazoline derivatives which have the general formula (I) shown below wherein the substituents have the meanings defined in claim 1 and which have utility as platelet lowering agents in humans. The compounds of the present invention function by inhibiting the formation of blood platelets.
    Type: Application
    Filed: May 13, 2009
    Publication date: June 2, 2011
    Applicant: Shire LLC
    Inventors: Bernard Golding, Peter Cicala, Richard Franklin, Angus Macleod
  • SUBSTITUTED QUINAZOLINES AS BLOOD PLATELET LOWERING AGENTS
    Publication number: 20110130405
    Abstract: This invention relates to the discovery of 3-and 5-substituted analogues of the selective platelet lowering agent anagrelide with reduced potential for cardiovascular side-effects which should lead to improved patient compliance and safety in the treatment of myeloproliferative diseases. More specifically, the present invention relates to certain imidazoquinazoline derivatives which have the general formula (I) shown below wherein the meanings of the substituents are defined in claim 1 and which have utility as platelet lowering agents in humans. The compounds of the present invention function by inhibiting megakaryocytopoeisis and hence the formation of blood platelets.
    Type: Application
    Filed: May 13, 2009
    Publication date: June 2, 2011
    Applicant: Shire LLC
    Inventors: Bernard Golding, Richard Franklin, Kim Hirst
  • GASOLINE SULFUR REDUCTION CATALYST FOR FLUID CATALYTIC CRACKING PROCESS
    Publication number: 20110120911
    Abstract: The invention is a composition that is suitable for reducing sulfur species from products produced by petroleum refining processes, especially gasoline products produced by fluidized catalytic cracking (FCC) processes. The composition comprises zeolite, yttrium, and at least one element selected from the group consisting of zinc, magnesium and manganese, wherein the yttrium and element are present as cations. The yttrium and zinc are preferably present as cations that have been exchanged onto the zeolite. The zeolite is preferably a zeolite Y.
    Type: Application
    Filed: February 1, 2011
    Publication date: May 26, 2011
    Inventors: Ruizhong Hu, Richard Franklin Wormsbecher
  • FAULT MANAGEMENT IN VIRTUAL COMPUTING ENVIRONMENTS
    Publication number: 20110107148
    Abstract: A method and system for fault management in virtual computing environments are provided. The system includes: a monitor of fault events from virtual machines and host devices in a virtual computing environment and a monitor of situation events in the virtual computing environment wherein the situation events refer to a virtual machine name and a host device name. A universal faults component determines if a fault event affects both virtual machines and host devices and a correlating component correlates fault events relating to virtual machines and host devices as relating to the same problem. Host machine fault events correlated to a problem are marked as a root event and virtual machine fault events correlated to a problem are marked as symptoms with a link to the root event.
    Type: Application
    Filed: May 11, 2010
    Publication date: May 5, 2011
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventor: David Richard Franklin
  • Processing Network Events
    Publication number: 20110106941
    Abstract: Processing network events generates multiple events from a single network device event. The system includes a network monitoring device for acquiring event data and a processing system for receiving an input event from a network monitoring device on a processing thread, wherein the processing system includes a communications thread generating component for generating multiple communications threads each for transmitting event data to a server database. The communication threads open connections to required server databases and these connections are maintained in an open state while the network monitoring device is running.
    Type: Application
    Filed: May 19, 2010
    Publication date: May 5, 2011
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventor: David Richard Franklin
  • GALANTAMINE AMINO ACID AND PEPTIDE PRODRUGS AND USES THEREOF
    Publication number: 20110098278
    Abstract: Prodrugs of galantamine or its 3-hydroxy metabolite with amino acids or short peptides, pharmaceutical compositions containing such prodrugs and methods for treating a memory or cognition disorder with the galantamine prodrugs are provided herein. Prodrugs having side chains of valine, phenylalanine, tyrosine or para amino benzoic acid and mono-, di- and tripeptides thereof are preferred. Additionally, methods for avoiding or minimizing the adverse gastrointestinal side effects associated with galantamine administration, as well as improving the pharmacokinetics of galantamine are provided herein.
    Type: Application
    Filed: July 23, 2010
    Publication date: April 28, 2011
    Applicant: Shire LLC
    Inventors: Richard Franklin, Bernard T. Golding, Robert G. Tyson
  • SUBSTITUTED QUINAZOLINES AND THEIR USES FOR MYEOLOPROLIFIC AND THROMBOTIC DISEASES
    Publication number: 20110086851
    Abstract: This invention relates to the discovery of substituted analogues of the selective platelet lowering agent anagrelide with reduced potential for cardiovascular side-effects which should lead to improved patient compliance and safety in the treatment of myeloproliferative diseases. More specifically, the present invention relates to certain imidazoquinazoline derivatives which have the general formula shown below wherein the substituents have the meanings defined in claim 1: and which have utility as platelet lowering agents in humans. The compounds of the present invention function by inhibiting megakaryocytopoeisis and hence the formation of blood platelets.
    Type: Application
    Filed: May 13, 2009
    Publication date: April 14, 2011
    Inventors: Bernard Golding, Richard Franklin
  • ELECTRONIC PHANTOM AND METHOD FOR ELECTRONICALLY CONTROLLING A PHANTOM FOR A QUANTITATIVE ULTRASOUND DEVICE
    Publication number: 20110076659
    Abstract: An electronic phantom and method for electronically controlling a phantom for a quantitative ultrasound device are provided. The electronic phantom includes a housing, a first transducer element within the housing configured to receive an ultrasonic signal from a quantitative ultrasound device and a second transducer element within the housing connected to the first transducer element. The second transducer element is configured to transmit a modified ultrasonic sound wave to the quantitative ultrasound device based on the received ultrasonic signal. The first and second transducer elements are positioned in a back to back configuration within the housing.
    Type: Application
    Filed: September 30, 2009
    Publication date: March 31, 2011
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Richard Franklin Morris, Steven Taylor Morris
  • PHANTOM FOR A QUANTITATIVE ULTRASOUND DEVICE
    Publication number: 20110076660
    Abstract: A phantom for a quantitative ultrasound device is provided. The phantom includes a hollow casing, a first acoustic element disposed within the hollow casing, the first acoustic element simulating a broadband ultrasonic attenuation (BUA) of an exemplary bone; and a second acoustic element disposed within the hollow casing, the second acoustic element altering a speed of an ultrasonic signal transmitted through the phantom, the second acoustic element being disposed in-line with the first acoustic element. The phantom also includes a third acoustic element disposed within the hollow casing, the third acoustic element forming an acoustic coupling agent between the first acoustic element and the second acoustic element. A method of fabricating a phantom is also described herein.
    Type: Application
    Filed: September 30, 2009
    Publication date: March 31, 2011
    Applicant: GENERAL ELECTRIC COMPANY
    Inventors: Richard Franklin Morris, Steven Taylor Morris
  • 2H- PYRIMIDO [2, 1-B] QUINAZOLIN-2-ONE DERIVATIVES AND THEIR USE AS PLATELET ANTI-AGGREGATIVE AGENTS
    Publication number: 20110071171
    Abstract: This invention relates to the discovery of substituted analogues of the selective platelet lowering agent anagrelide with reduced potential for cardiovascular side-effects which should lead to improved patient compliance and safety in the treatment of myeloproliferative diseases. More specifically, the present invention relates to certain imidazoquinazoline derivatives which have the general formula shown below wherein the substituents have the meanings defined in claim 1: and which have utility as platelet lowering agents in humans. The compounds of the present invention function by inhibiting megakaryocytopoeisis and hence the formation of blood platelets.
    Type: Application
    Filed: May 13, 2009
    Publication date: March 24, 2011
    Applicant: Shire LLC
    Inventors: Bernard Golding, Richard Franklin
  • SUBSTITUTED QUINAZOLINES
    Publication number: 20110071174
    Abstract: This invention relates to the discovery of substituted analogues of the selective platelet lowering agent anagrelide with reduced potential for cardiovascular side-effects which should lead to improved patient compliance and safety in the treatment of myeloproliferative diseases. More specifically, the present invention relates to certain imidazoquinazoline derivatives which have the general formula shown below wherein the substituents have the meanings defined in claim 1: and which have utility as platelet lowering agents in humans. The compounds of the present invention function by inhibiting megakaryocytopoeisis and hence the formation of blood platelets.
    Type: Application
    Filed: May 13, 2009
    Publication date: March 24, 2011
    Inventors: Bernard Golding, Richard Franklin
  • IMIDAZOQUINAZOLINE DERIVATIVES AS ANAGRELIDE ANALOGUES FOR THE TREATMENT OF MYELOPROLIFIC DISEASES AND THROMBOTIC DISEASES
    Publication number: 20110071173
    Abstract: This invention relates to the discovery of substituted analogues of the selective platelet lowering agent anagrelide with reduced potential for cardiovascular side-effects which should lead to improved patient compliance and safety in the treatment of myeloproliferative diseases. More specifically, the present invention relates to certain imidazoquinazoline derivatives which have the general formula shown below wherein the substituents have the meanings defined in claim 1: and which have utility as platelet lowering agents in humans. The compounds of the present invention function by inhibiting megakaryocytopoeisis and hence the formation of blood platelets.
    Type: Application
    Filed: May 13, 2009
    Publication date: March 24, 2011
    Inventors: Bernard Golding, Richard Franklin, Angus Macleod
  • SUBSTITUTED QUINAZOLINES AS BLOOD PLATELET LOWERING AGENTS
    Publication number: 20110071172
    Abstract: This invention relates to the discovery of substituted analogues of the selective platelet lowering agent anagrelide with reduced potential for cardiovascular side-effects which should lead to improved patient compliance and safety in the treatment of myeloproliferative diseases. More specifically, the present invention relates to certain imidazoquinazoline derivatives which have the general formula shown below wherein the substituents have the meanings defined in claim (I): and which have utility as platelet lowering agents in humans. The compounds of the present invention function by inhibiting megakaryocytopoeisis and hence the formation of blood platelets.
    Type: Application
    Filed: May 13, 2009
    Publication date: March 24, 2011
    Applicant: Shire LLC
    Inventors: Bernard Golding, Richard Franklin
  • Substituted quinazolines
    Patent number: 7910597
    Abstract: This invention relates to the discovery of 3- and 5-substituted analogues of the selective platelet lowering agent anagrelide with reduced potential for cardiovascular side-effects which should lead to improved patient compliance and safety in the treatment of myeloproliferative diseases. More specifically, the present invention relates to certain imidazoquinazoline derivatives which have utility as platelet lowering agents in humans. The compounds of the present invention function by inhibiting megakaryocytopoeisis and hence the formation of blood platelets.
    Type: Grant
    Filed: November 28, 2007
    Date of Patent: March 22, 2011
    Assignee: Shire LLC
    Inventors: Richard Franklin, Bernard T. Golding
  • SUBSTITUTED QUINAZOLINES
    Publication number: 20110065735
    Abstract: This invention relates to the discovery of substituted analogues of the selective platelet lowering agent anagrelide with reduced potential for cardiovascular side-effects which should lead to improved patient compliance and safety in the treatment of myeloproliferative diseases. More specifically, the present invention relates to certain imidazoquinazoline derivatives which have the general formula shown below wherein the substituents have the meanings defined in claim 1: and which have utility as platelet lowering agents in humans. The compounds of the present invention function by inhibiting megakaryocytopoeisis and hence the formation of blood platelets.
    Type: Application
    Filed: May 13, 2009
    Publication date: March 17, 2011
    Applicant: Shire LLC
    Inventors: Bernard Golding, Richard Franklin, Peter Cicala
  • SUBSTITUTED QUINAZOLINES
    Publication number: 20110065714
    Abstract: This invention relates to the discovery of 3-and 5-substituted analogues of the selective platelet lowering agent anagrelide with reduced potential for cardiovascular side-effects which should lead to improved patient compliance and safety in the treatment of myeloproliferative diseases. More specifically, the present invention relates to certain imidazoquinazoline derivatives which have the general formula shown below wherein the substituents have the meanings defined in claim 1: and which have utility as platelet lowering agents in humans. The compounds of the present invention function by inhibiting megakaryocytopoeisis and hence the formation of blood platelets.
    Type: Application
    Filed: May 13, 2009
    Publication date: March 17, 2011
    Applicant: Shire LLC
    Inventors: Bernard Golding, Peter Cicala, Richard Franklin, Kim Hirst