Patents by Inventor Richard R. Bott

Richard R. Bott has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Serine proteases of the bacillus gibsonii-clade
    Patent number: 10533165
    Abstract: The present disclosure relates to serine proteases cloned from Bacillus gibsonii, and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.
    Type: Grant
    Filed: December 12, 2014
    Date of Patent: January 14, 2020
    Assignee: DANISCO US INC
    Inventors: Marc Kolkman, Rie Mejldal, Frits Goedegebuur, Lilia Maria Babe, Anja Hemmingsen Kellett-Smith, Harm Mulder, Richard R. Bott, Miles Christopher Scotcher
  • Modified glucosyltransferases for producing branched alpha-glucan polymers
    Patent number: 10508268
    Abstract: Glucosyltransferase enzymes are disclosed herein that produce branched alpha-glucan polymer. Also disclosed, for example, are polynucleotides encoding these enzymes, as well as methods of producing branched alpha-glucan polymer.
    Type: Grant
    Filed: April 18, 2018
    Date of Patent: December 17, 2019
    Assignee: DUPONT INDUSTRIAL BIOSCIENCES USA, LLC
    Inventors: Mark S. Payne, Yefim Brun, Richard R. Bott
  • POLYPEPTIDES WITH ENDOGLUCANASE ACTIVITY AND USES THEREOF
    Publication number: 20190367894
    Abstract: Disclosed herein are cellulase variants, or active fragments thereof, and polynucleotides encoding same, wherein the cellulase variants, or active fragments thereof, have endoglucanase activity. Also disclosed herein are compositions comprising said cellulase variants, or active fragments thereof; vectors and/or host cells comprising the polynucleotides encoding said cellulase variants, or active fragments thereof; and methods for making and/or using said cellulase variants, or active fragments thereof and/or compositions containing same; wherein said cellulase variants, or active fragments thereof, have endoglucanase activity.
    Type: Application
    Filed: December 14, 2017
    Publication date: December 5, 2019
    Inventors: Richard R. Bott, David A. Estell, Neeraj Pandey, Sina Pricelius, Jian Yao
  • PROTEASE VARIANTS AND USES THEREOF
    Publication number: 20190309278
    Abstract: Disclosed herein is one or more subtilisin variants, nucleic acids encoding same, and compositions and methods related to the production and uses thereof, including one or more subtilisin variants that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: June 18, 2017
    Publication date: October 10, 2019
    Inventors: Richard R. Bott, David A. Estell, Frits Goedegebuur, Harm Mulder, Sina Pricelius
  • ENGINEERED GLUCOSYLTRANSFERASES
    Publication number: 20190292528
    Abstract: Disclosed herein are glucosyltransferases with modified amino acid sequences. Such engineered enzymes exhibit improved alpha-glucan product yields and/or lower leucrose yields, for example. Further disclosed are reactions and methods in which engineered glucosyltransferases are used to produce alpha-glucan.
    Type: Application
    Filed: April 11, 2019
    Publication date: September 26, 2019
    Inventors: Yougen Li, Mark S. Payne, Jared B. Parker, Slavko Kralj, Veli Alkan, Richard R. Bott, Robert Dicosimo, Qiong Cheng, Ellen D. Semke, Susan Marie Hennessey
  • SERINE PROTEASES OF BACILLUS SPECIES
    Publication number: 20190185838
    Abstract: The present disclosure relates to serine proteases cloned from Bacillus spp., and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.
    Type: Application
    Filed: February 27, 2019
    Publication date: June 20, 2019
    Inventors: MARC KOLKMAN, ANJA HEMMINGSEN KELLETT-SMITH, RIE MEJLDAL, RICHARD R. BOTT, LILIA MARIE BABE
  • Engineered glucosyltransferases
    Patent number: 10301604
    Abstract: Disclosed herein are glucosyltransferases with modified amino acid sequences. Such engineered enzymes exhibit improved alpha-glucan product yields and/or lower leucrose yields, for example. Further disclosed are reactions and methods in which engineered glucosyltransferases are used to produce alpha-glucan.
    Type: Grant
    Filed: September 13, 2017
    Date of Patent: May 28, 2019
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Yougen Li, Mark S. Payne, Jared B. Parker, Slavko Kralj, Veli Alkan, Richard R. Bott, Robert Dicosimo, Qiong Cheng, Ellen D. Semke, Susan Marie Hennessey
  • GLUCOSYLTRANSFERASE AMINO ACID MOTIFS FOR ENZYMATIC PRODUCTION OF LINEAR POLY ALPHA-1,3-GLUCAN
    Publication number: 20190112585
    Abstract: Reactions comprising water, sucrose, and one or more glucosyltransferase enzymes are disclosed herein. Glucosyltransferase enzymes used in these reactions comprise certain motifs allowing production of insoluble poly alpha-1,3-glucan having at least 95% alpha-1,3 glycosidic linkages.
    Type: Application
    Filed: November 14, 2018
    Publication date: April 18, 2019
    Inventors: Mark S. Payne, Yefim Brun, Richard R. Bott
  • POLYPEPTIDES WITH ENDOGLUCANASE ACTIVITY AND USES THEREOF
    Publication number: 20180362946
    Abstract: Disclosed herein are cellulase variants, or active fragments thereof, and polynucleotides encoding same, wherein the cellulase variants, or active fragments thereof, hav endoglucanase activity. Also disclosed herein are compositions comprising said cellulase variants, or active fragments thereof; vectors and/or host cells comprising the polynucleotides encoding said cellulase variants, or active fragments thereof; and methods for making and/or using said cellulase variants, or active fragments thereof and/or compositions containing same; wherein said cellulase variants, or active fragments thereof, have endoglucanase activity.
    Type: Application
    Filed: December 16, 2016
    Publication date: December 20, 2018
    Inventors: Neeraj Pandey, Richard R. Bott, Sina Pricelius, Annapurna Sachan, Stepan Shipovskov, Ajit Satapathy
  • PAENIBACILLUS AND BACILLUS SPP. MANNANASES
    Publication number: 20180320158
    Abstract: Disclosed herein are mannanases from Paenibacillus or Bacillus spp, polynucleotides encoding the mannanases, compositions containing the mannanases, and methods of use thereof. Compositions containing mannanases are suitable for use as detergents and for cleaning fabrics and hard surfaces, as well as in a variety of other industrial applications.
    Type: Application
    Filed: November 7, 2016
    Publication date: November 8, 2018
    Inventors: Kai Bao, Carol Marie Fioresi, Dina Finan, Christian D. Adams, Viktor Yuryevich Alekseyev, Richard R. Bott, Christopher L. Rife
  • MODIFIED GLUCOSYLTRANSFERASES FOR PRODUCING BRANCHED ALPHA-GLUCAN POLYMERS
    Publication number: 20180305672
    Abstract: Glucosyltransferase enzymes are disclosed herein that produce branched alpha-glucan polymer. Also disclosed, for example, are polynucleotides encoding these enzymes, as well as methods of producing branched alpha-glucan polymer.
    Type: Application
    Filed: April 18, 2018
    Publication date: October 25, 2018
    Inventors: MARK S. PAYNE, YEFIM BRUN, RICHARD R. BOTT
  • SERINE PROTEASES OF BACILLUS SPECIES
    Publication number: 20180251743
    Abstract: The present disclosure relates to serine proteases cloned from Bacillus Akibai and Bacillus Clarkii, and variants thereof. Compositions containing the serine proteases are suitable for use in cleaning fabrics and hard surfaces, as well as in a variety of industrial applications.
    Type: Application
    Filed: May 21, 2018
    Publication date: September 6, 2018
    Inventors: MARC KOLKMAN, RIE MEJLDAL, ANJA HEMMINGSEN KELLETT SMITH, LILIA MARIA BABE, RICHARD R. BOTT
  • BACILLUS GIBSONII-CLADE SERINE PROTEASES
    Publication number: 20180237761
    Abstract: Disclosed herein is one or more subtilisin variant, nucleic acid encoding same, and compositions and methods related to the production and use thereof, including one or more Bacillus gibsonii-clade subtilisin variant that has improved stability and/or soil removal compared to one or more reference subtilisin.
    Type: Application
    Filed: June 17, 2016
    Publication date: August 23, 2018
    Inventors: Lilia Maria Babe, Richard R. Bott, David A. Estell, Harm Mulder, Frits Goedegebuur, Jian Yao, Sina Pricelius, Miles Scotcher
  • COMPOSITIONS AND METHODS COMPRISING LG12-CLADE PROTEASE VARIANTS
    Publication number: 20180216090
    Abstract: The present disclosure provides LG12-clade enzyme variants, compositions comprising these enzyme variants, and method of using these enzymes and compositions, as well as the polynucleotides encoding these enzymes, the vectors comprising these polynucleotides, and the host cells transformed with such vectors.
    Type: Application
    Filed: March 14, 2016
    Publication date: August 2, 2018
    Inventors: Harm Mulder, Jeffrey Veach Miller, Frits Goedegebuur, David A. Estell, Katherine Augustyn, Lilia Maria Babe, Richard R. Bott, Miles Christopher Scotcher, Jian Yao
  • Modified glucosyltransferases for producing branched alpha-glucan polymers
    Patent number: 9988610
    Abstract: Glucosyltransferase enzymes are disclosed herein that produce branched alpha-glucan polymer. Also disclosed, for example, are polynucleotides encoding these enzymes, as well as methods of producing branched alpha-glucan polymer.
    Type: Grant
    Filed: June 15, 2016
    Date of Patent: June 5, 2018
    Assignee: E I DU PONT DE NEMOURS AND COMPANY
    Inventors: Mark S Payne, Yefim Brun, Richard R Bott
  • AMYLASE WITH MALTOGENIC PROPERTIES
    Publication number: 20180112203
    Abstract: The present teachings provide an amylase with maltogenic properties. Nucleic acids encoding the maltogenic amylase and variants thereof, expression vectors, formulations, and host cells are also provided. Additional embodiments of the present teachings provide various methods of use and methods of manufacturing.
    Type: Application
    Filed: November 15, 2013
    Publication date: April 26, 2018
    Applicant: DANISCO US INC.
    Inventors: RICHARD R. BOTT, LING HUA, ZHEN QIAN, CHRISTOPHER L. RIFE, JAYARAMA K. SHETTY, ZHONGMEI TANG, ZHEYONG YU, BO ZHANG
  • AprL-CLADE PROTEASE VARIANTS AND USES THEREOF
    Publication number: 20180112204
    Abstract: The present disclosure provides AprL-clade protease enzymes, including variant AprL-clade protease enzymes, nucleic acids encoding same, and compositions and methods related to the production and use thereof, including an AprL-clade variant subtilisin enzyme that has improved stability and/or soil removal compared to a parent AprL-clade subtilisin enzyme.
    Type: Application
    Filed: May 13, 2016
    Publication date: April 26, 2018
    Inventors: David A. Estell, Frits Goedegebuur, Marc Kolkman, Rie Mejldal, Katherine Augustyn, Lilia Maria Babe, Richard R. Bott, Jian Yao, Roopa Ghirnikar
  • Variants of cellobiohydrolases
    Patent number: 9938551
    Abstract: Disclosed are a number of homologs and variants of Hypocrea jecorina Ce17A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.
    Type: Grant
    Filed: December 10, 2013
    Date of Patent: April 10, 2018
    Assignee: DANISCO US INC
    Inventors: Richard R. Bott, Maria Foukaraki, Ronaldus Wilhelmus Hommes, Thijs Kaper, Bradley R. Kelemen, Slavko Kralj, Igor Nikolaev, Mats Sandgren, Johannes Franciscus Thomas Van Lieshout, Sander Van Stigt Thans
  • ENGINEERED GLUCOSYLTRANSFERASES
    Publication number: 20180072998
    Abstract: Disclosed herein are glucosyltransferases with modified amino acid sequences. Such engineered enzymes exhibit improved alpha-glucan product yields and/or lower leucrose yields, for example. Further disclosed are reactions and methods in which engineered glucosyltransferases are used to produce alpha-glucan.
    Type: Application
    Filed: September 13, 2017
    Publication date: March 15, 2018
    Inventors: YOUGEN LI, SUSAN MARIE HENNESSEY, SLAVKO KRALJ, MARK S. PAYNE, VELI ALKAN, QIONG CHENG, ROBERT DICOSIMO, ELLEN D SEMKE, JARED B. PARKER, RICHARD R. BOTT
  • NOVEL METALLOPROTEASES
    Publication number: 20180073006
    Abstract: Aspects of the present compositions and methods relate to novel metalloproteases polynucleotides encoding the novel metalloprotease, compositions and methods for use thereof.
    Type: Application
    Filed: October 5, 2017
    Publication date: March 15, 2018
    Inventors: Lilia M. Babe, Richard R. Bott, Roopa Ghirnikar, Frits Goedegebuur, Xiaogang Gu, Marc Kolkman, Jian Yao, Shukun Yu