Abstract: A closure assembly for a medical device such as a syringe comprises a housing having an open end and a hollow interior. A tip cap is removably disposed within the housing and includes a cover connected to the open end by a snap-fit connection. An indicator ring includes an access opening and is removably connected to the cover in interruptive, removable restricting relation to said tip cap. The access opening is dimensioned to facilitate passage of the syringe therethrough into attachment with the tip cap, with the tip cap disposed into disconnecting engagement with said indicator ring concurrent to removal of said tip cap and attached syringe through said open end. Upon removal of the tip cap and attached syringe through the open end of the housing, the indicator ring will be disposed in a surrounding captured disposition on the syringe, thereby providing a clear indication of tampering or use.

Abstract: A system for providing the collection of advanced, improved, and novel new components and elements in a single package to simplify assembly and use of the infusion set by the user, including one or more of an exemplary pushbutton-type inserter, squeeze-type inserter, contact-type inserter, skin pinching-type inserter, folding retraction-type inserter, and/or multistage-type inserter (700) having at least one reusable stage, an exemplary set (350) having an adhesion means with two or more user-selectable degrees of adhesion strength, a self-sealing tube connection means, a lens feature to view a site beneath the set, exemplary tube management and connection elements (450), insulin supply (475), adhesion concealment means (500), finger loops on the inserter and site preparation wipes or sprays (550) which can be provided as part of the inserter.

Abstract: A system for providing the collection of advanced, improved, and novel new components and elements in a single package to simplify assembly and use of the infusion set by the user, including one or more of an exemplary pushbutton-type inserter, squeeze-type inserter, contact-type inserter, skin pinching-type inserter, folding retraction-type inserter, and/or multistage-type inserter (700) having at least one reusable stage, an exemplary set (350) having an adhesion means with two or more user-selectable degrees of adhesion strength, a self-sealing tube connection means, a lens feature to view a site beneath the set, exemplary tube management and connection elements (450), insulin supply (475), adhesion concealment means (500), finger loops on the inserter and site preparation wipes or sprays (550) which can be provided as part of the inserter.

Abstract: A system for providing the collection of advanced, improved, and novel new components and elements in a single package to simplify assembly and use of the infusion set by the user, including one or more of an exemplary pushbutton-type inserter, squeeze-type inserter, contact-type inserter, skin pinching-type inserter, folding retraction-type inserter, and/or multistage-type inserter (700) having at least one reusable stage, an exemplary set (350) having an adhesion means with two or more user-selectable degrees of adhesion strength, a self-sealing tube connection means, a lens feature to view a site beneath the set, exemplary tube management and connection elements (450), insulin supply (475), adhesion concealment means (500), finger loops on the inserter and site preparation wipes or sprays (550) which can be provided as part of the inserter.

Abstract: An infusion set, patch pump, or elements thereof, having an exemplary catheter (14) provided with one or more channels, grooves and coatings (24, 34, 44), configured and arranged to provide a degree of strength and flexibility. The catheter (14) can also have an exemplary flexible union with the hub (12) having at least one of a ball-and-socket joint (66, 68), a sliding plate (86), and a flexible bushing (106), and which is sealed to allow even further movement of the catheter (14) while preventing leakage of medication through the junction. In doing so, a number of benefits associated with the use of rigid materials in catheter construction can be provided while at the same time, benefits associated with the use of flexible materials in catheter construction and/or flexible engagement with the hub can also be provided.

Abstract: A single package infusion set is provided, including one or more of the following inserters: pushbutton-type, squeeze-type, contact-type, skin pinching-type, folding retraction-type, or multistage-type inserter having at least one reusable stage. The infusion set further includes adhesion means with user-selectable degrees of adhesion strength, self-sealing tube connection means, a lens feature to view, a site beneath the set, exemplary tube management and connection elements, insulin supply, adhesion concealment means, finger loops on the inserter and site preparation wipes or sprays, optionally provided as part of the inserter. The system further includes a package which may hold a number of easily released sets, retrievable by an inserter, an exemplary insertion needle handle and shroud, an exemplary squeeze-type latch between an upper portion and a lower portion of the set, and/or a tool removable upper portion of the set.

Abstract: A tamper evident closure, intended primarily for a luer-slip or like frictional connection between one or more components associated with the closure and a syringe or other medical device, includes a housing having an open end and a tip cap disposed within the housing. An indicator member is connected to the housing in at least partially covering relation to the open end and includes an access opening disposed in accessible relation with the tip cap. A cover is removably disposed in overlying engagement with at least a portion of said indicator member in covering relation to the access opening. The indicator member has an inner segment disposed in contiguous surrounding relation to the access opening and has a reduced breakaway resistance, capable of being easily ruptured, ripped or torn during passage of said tip cap through the access opening, concurrent to the tip cap being connected to the medical device.

Abstract: A system for handling and dispensing a plurality of products, including a package having a chamber configured to contain the plurality of products in a predetermined aligned relation to one another and a base disposed in surrounding relation to said chamber. A retaining structure is disposed within an interior of the base in retaining relation with the plurality of products and an access device is disposable in opening engagement with the retaining structure and in accessible relation with an interior of the chamber and the plurality of products therein. The access device comprises a path of travel of the plurality of products out of said chamber when disposed in opening relation to the retaining structure and is structured to assume an interface orientation wherein said access device is disposed in interconnected relation between the package and a dispensing assembly.

Abstract: A medicant injection device includes a compressible body, a tip, and an outer luer body. The compressible body has a proximal end, a distal end, and a plurality of bellows, and defines an inner cavity for holding a liquid medicant. The tip is positioned at the proximal end of the compressible body. The outer luer body includes internal threads, and is positioned over and engaged with the tip to form a first fitting therewith. The first fitting is configured to be connected with a second fitting. A medicant injection device includes a compressible body having first and second arms, a receptacle interconnected with the compressible body and defining an inner cavity, and a first fitting configured to engage a second fitting. The compressible body is configured to be compressed by forcing the distal end of the first and second arm toward each other.

Abstract: A tamper evident assembly for retaining a plunger and piston within a barrel of a syringe including an elongated tether and a cover connected to the tether and concurrently disposed in an operative position on the syringe. A connector assembly adjustably and fixedly interconnects the tether to the cover in the operative position, wherein the cover is connected in covering relation to a discharge port of the syringe concurrently to a proximal end of the tether being connected to the syringe barrel in a removal preventative relation to the piston. Movable adjustment of the tether relative to the connector assembly defines a retaining segment disposed into a taut, fixed length orientation between the proximal end of the tether and the cover, to further define the operative position.

Abstract: A medicant injection device includes a compressible body, a tip, and an outer luer body. The compressible body has a proximal end, a distal end, and a plurality of bellows, and defines an inner cavity for holding a liquid medicant. The tip is positioned at the proximal end of the compressible body. The outer luer body includes internal threads, and is positioned over and engaged with the tip to form a first fitting therewith. The first fitting is configured to be connected with a second fitting. A medicant injection device includes a compressible body having first and second arms, a receptacle interconnected with the compressible body and defining an inner cavity, and a first fitting configured to engage a second fitting. The compressible body is configured to be compressed by forcing the distal end of the first and second arm toward each other.

Abstract: A needle changing device for use on a medication delivery device includes an engagement element that is configured to engage the medication delivery device and pierce a septum of the medication delivery device, a needle holder connected to the engagement element, the needle holder having a needle changing septum having a reservoir, the reservoir being in continuous fluid communication with the engagement element, and a plurality of needles configured to pierce the needle changing septum, wherein when the needle holder is in a first position, the plurality of needles are disengaged from the reservoir of the needle changing septum, and when the needle holder is in a second position, one of the plurality of needles enters into fluid communication with the reservoir of the needle changing septum and is partially exposed outside the needle changing device for medicament delivery.

Abstract: A package for a medical cannula with a hub, such as a pen needle, is disclosed. The package includes a cover for receiving a medical cannula and for engaging a hub of the medical cannula. The cover has open ends that are in communication through the cover. The packaging also includes a sterility barrier for the cover.

Abstract: Vial dosing systems and methods are disclosed. A vial dosing device includes a connecting body coupleable to a vial, a cannulated plunger having a proximal end coupled to the connecting body, a dose chamber adapted to slidably receive a distal end of the cannulated plunger and to expel medicament through a distal end of the dose chamber, and a plunger tip check valve coupled to the cannulated plunger and adapted for fluid flow from the cannulated plunger through the plunger tip check valve into the dose chamber.

Abstract: In one aspect, a safety pen needle assembly is provided herein which includes a hub with a needle fixed to the hub, the needle having a distal end, formed for insertion into a patient, and a proximal end. The assembly further includes a shield and a biasing member disposed between the hub and the shield configured to urge the shield distally. A protrusion extends from at least one of the hub and the shield with a channel being formed in at least the other of the hub and the shield. The channel is formed to accommodate the protrusion. The shield is movable from a first position to a second position. In the first position, the shield is spaced from the distal end of the needle such that the distal end of the needle is exposed. In the second position, the shield covers the distal end of the needle. The channel guides the protrusion as the shield moves from the first position to the second position. With this arrangement, a shield may be directed to move in a desired path with stability.

Abstract: In one aspect, a safety pen needle assembly is provided herein which includes a hub with a needle fixed to the hub, the needle having a distal end, formed for insertion into a patient, and a proximal end. The assembly further includes a shield and a biasing member disposed between the hub and the shield configured to urge the shield distally. A protrusion extends from at least one of the hub and the shield with a channel being formed in at least the other of the hub and the shield. The channel is formed to accommodate the protrusion. The shield is movable from a first position to a second position. In the first position, the shield is spaced from the distal end of the needle such that the distal end of the needle is exposed. In the second position, the shield covers the distal end of the needle. The channel guides the protrusion as the shield moves from the first position to the second position. With this arrangement, a shield may be directed to move in a desired path with stability.

Abstract: In one aspect, a pen needle assembly is provided herein which includes a hub, and a needle fixed to the hub, the needle having proximal and distal ends with a lumen extending therebetween. The needle extends distally from the hub to define an exposed length between the distal end of the needle and the hub in the range of about 5.0 to 9.0 mm. The hub defines a post formed about the needle, the post having a distally-facing first skin engaging surface. The exposed length of the needle extends distally from the first skin engaging surface. The hub also defines a distally-facing second skin engaging surface which at least partially circumscribes the first skin engaging surface. The second skin engaging surface being located proximally of the first skin engaging surface. Advantageously, a pen needle assembly is provided having two skin engaging surfaces which provide stability in achieving subcutaneous injections.

Abstract: A pen needle, comprising a reusable adapter configured for attachment to a distal end of a medication pen, the adapter having a proximal needle for accessing the interior of the pen injector and a fitting on the distal side for mating with a patient end needle assembly, and a disposable patient-end needle assembly having a base configured for mating with the fitting on the distal side of the adapter and a patient-end needle extending from a distal end of the base.

Abstract: A high pressure delivery system for delivering a medicament, comprising a first chamber for storing a supply of the medicament, a gear pump assembly in fluid communication with the first chamber, said gear pump assembly having a dose inlet and a dose discharge, said dose inlet having a larger diameter than said dose discharge to provide a high pressure discharge, and a fluid connection path in fluid communication with the gear pump assembly for delivering the medicament to a high pressure area.