Abstract: Disclosed herein are dosing regimens for a NaPi2b-targeted antibody-drug conjugates for treating recurrent, platinum-sensitive ovarian cancer.

Abstract: Disclose herein are dosing regimens for a combination of carboplatin and a targeted NaPi2b antibody-drug conjugates for treating cancer.

Abstract: A method for predicting the availability of a charging station for a vehicle with a driver assistance system is provided. The method includes establishing an expected time of arrival of the vehicle at the charging station LS, and determining an expected availability of the charging station at the time of arrival, wherein at least one user feedback about the correctness of a prediction of the availability of the charging station in the past is taken into account. Moreover, a driver assistance system for carrying out the method is provided.

Abstract: A roof cover of a building under construction includes a heat shrinkable film stretched over the roof framing of said building under construction. The film brought into conformity with said roof framing through application of heat. The film may be formed by a number of adjoining sheets or strips of material.

Abstract: A luminaire system is provided that has directional light projection optics combined with a light distribution modifier to produce a non-uniform angular light intensity distribution from a single or array of light sources. The luminaire system provides for light intensity distribution with directional asymmetry meeting the specifications and requirements of aviation obstruction lights. The light distribution modifier component or subassembly redirects, scatters, refracts, diffracts and/or blocks part of the projection light in the distribution of the primary optics that would otherwise produce ground scatter. Unlike peripheral light shields at the marginal limits of the light distribution from the luminaire light system, the light distribution modifier is located near to the optical axis of the projection optics system.

Abstract: A luminaire system is provided that has directional light projection optics combined with a light distribution modifier to produce a non-uniform angular light intensity distribution from a single or array of light sources. The luminaire system provides for light intensity distribution with directional asymmetry meeting the specifications and requirements of aviation obstruction lights. The light distribution modifier component or subassembly redirects, scatters, refracts, diffracts and/or blocks part of the projection light in the distribution of the primary optics that would otherwise produce ground scatter. Unlike peripheral light shields at the marginal limits of the light distribution from the luminaire light system, the light distribution modifier is located near to the optical axis of the projection optics system.

Abstract: A luminaire system is provided that has directional light projection optics combined with a light distribution modifier to produce a non-uniform angular light intensity distribution from a single or array of light sources. The luminaire system provides for light intensity distribution with directional asymmetry meeting the specifications and requirements of aviation obstruction lights. The light distribution modifier component or subassembly redirects, scatters, refracts, diffracts and/or blocks part of the projection light in the distribution of the primary optics that would otherwise produce ground scatter. Unlike peripheral light shields at the marginal limits of the light distribution from the luminaire light system, the light distribution modifier is located near to the optical axis of the projection optics system.

Abstract: A particle capture system that can be used in the context of a lab-on-a-chip platform for particle- and cell-based assays is described. The system comprises a capture chamber comprising a plurality of capture sites, the capture sites defining a capture area configured to receive individual particles travelling within the capture chamber. By rotating the chamber, the individual particles are biased towards the capture sites where they may be captured.

Abstract: A luminaire system is provided that has directional light projection optics combined with a light distribution modifier to produce a non-uniform angular light intensity distribution from a single or array of light sources. The luminaire system provides for light intensity distribution with directional asymmetry meeting the specifications and requirements of aviation obstruction lights. The light distribution modifier component or subassembly redirects, scatters, refracts, diffracts and/or blocks part of the projection light in the distribution of the primary optics that would otherwise produce ground scatter. Unlike peripheral light shields at the marginal limits of the light distribution from the luminaire light system, the light distribution modifier is located near to the optical axis of the projection optics system.

Abstract: A semiconductor device with a current terminal region located in a device active area of a substrate of the device. A guard region is located in a termination area of the device. A plurality of floating field plates are located in the termination area and are ohmically coupled to the guard region. The floating field plates and guard region act in some embodiments to “smooth” the electrical field distribution along the termination area.

Abstract: A method of and an arrangement for improving the lubrication system of a propulsion device of a marine vessel are specifically applicable in removing water from the lubrication oil of various types of thrusters. An inert gas is arranged from an inert gas source to flow through a gas cavity in the lubrication system for flushing moist gas from the cavity.

Abstract: A semiconductor device with a current terminal region located in a device active area of a substrate of the device. A guard region is located in a termination area of the device. A plurality of floating field plates are located in the termination area and are ohmically coupled to the guard region. The floating field plates and guard region act in some embodiments to “smooth” the electrical field distribution along the termination area.

Abstract: Microfluidic devices and in particular microfluidic devices incorporating a cascading valve arrangement for selectively controlling the flow of a fluid within the microfluidic device are described. Specific examples of a microfluidic device comprising a sacrificial valve (210) whose opening is triggered by the opening of a second valve (220), causing a retraction of a fluid spacer (213) thus bringing liquid (214) into contact with the dissolvable valve membrane (210).

Abstract: A method of and an arrangement for improving the lubrication system of a propulsion device of a marine vessel are specifically applicable in removing water from the lubrication oil of various types of thrusters. An inert gas is arranged from an inert gas source to flow through a gas cavity in the lubrication system for flushing moist gas from the cavity.

Abstract: A particle capture system that can be used in the context of a lab-on-a-chip platform for particle- and cell-based assays is described. The system comprises a capture chamber comprising a plurality of capture sites, the capture sites defining a capture area configured to receive individual particles travelling within the capture chamber. By rotating the chamber, the individual particles are biased towards the capture sites where they may be captured.

Abstract: A hand pruner having a first and second handle, the first handle having a hook, formed at a far end, the second handle having a cutting blade formed at the far end. The first handle and hook and second handle and blade pivotally connected for movement with respect to each other. The blade and second handle having a cup formed between the blade and second handle. The hook and first handle having a cup formed between the hook and first handle. The cutting edge of the hook is formed along two concave intersecting arcs of different diameters, the smaller diameter arc located next to the pivot. The cutting edge of the blade is formed along two convex intersecting arcs having diameters that complement the two concave arcs in the hook cutting edge.

Abstract: Devices for controlling fluid flow, in particular microfluidic devices, are described, which exploit gas/liquid interfaces to control liquid flow in accordance with application requirements. Devices for on/off flow switching, centrifugal separation, mixing, metering and aliquoting are described.