Abstract: Systems and methods are described that that dynamically configure high-speed data link lightpaths between access routers and backbone routers at geographically dispersed locations to reassign traffic when a backbone router fails or is removed from service. Embodiments reduce the quantity of backbone router ports used in dual backbone router-homed networks.

Abstract: Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12 ) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, of the invention are useful for detecting hIL-12 and for inhibiting hIL-12 activity, e.g., in a human subject suffering from a disorder in which hIL-12 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention.

Abstract: Antibodies that bind human interleukin-18 (hIL-18) are provided, in particular antibodies that bind epitope(s) of human IL-18. The antibodies can be, for example, entirely human antibodies, recombinant antibodies, or monoclonal antibodies. Preferred antibodies have high affinity for hIL-18 and neutralize hIL-18 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Method of making and method of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hIL-18 and for inhibiting hIL-18 activity, e.g., in a human subject suffering from a disorder in which hIL-18 activity is detrimental.

Abstract: Systems and methods are described for restoring IP traffic flows routed in an IP network in less than 100 ms after the IP network sustains a network failure. The systems and methods are a two-phase fast reroute that uses distributed optimized traffic engineering during backup tunnel restoration and end-to-end tunnel restoration that maximizes sharing among all independent failure scenarios and minimizes the total capacity, total cost, or a linear combination of the two. For defined failure condition scenarios, restoration traffic is routed using pre-computed backup tunnels using a constrained shortest path first method where link weights along the path are chosen dynamically and depend on available and total capacity of the link, latency, and other cost measures such as IP port costs. During the capacity allocation phase, the method reuses capacity already allocated for other independent failure scenarios as much as possible but also adds capacity, if necessary.

Abstract: An apparatus for testing aspects of how a child learns includes a toy-like base having upstanding pegs. The child is encouraged to place donut shaped hand pieces onto the pegs. The hand pieces test the ability of the child to discriminate between different colors, and separately between different textures and different shapes and also tests the child's abilities in perception and creativity. The base also is able to test the child's ability to discern and copy tones and rhythms. Information of the child's performance is automatically collected within the apparatus and then compared with a normative baseline. Remediation focuses on activities related to the learning channels where the child is least astute and periodic retesting measures the ability of the child to improve in those channels to enable improvement of remediation approaches.

Abstract: Computing device deployment and configuration using a mass storage device is provided. A generic computing device is provided to a customer or end user. A mass storage device is used to distribute configuration information to the generic computing device. The configuration information includes customer-specified or ordered software applications or other features. The configuration information can also include updates to the computing device system software. The customer or end user couples the mass storage device to the generic computing device in order to load the configuration information into the computing device. After the configuration information is loaded, the computing device is configured for the customer's use. Further features, such as creating customized images, are also provided.

Abstract: Computing device deployment and configuration using a mass storage device is provided. A generic computing device is provided to a customer or end user. A mass storage device is used to distribute configuration information to the generic computing device. The configuration information includes customer-specified or ordered software applications or other features. The configuration information can also include updates to the computing device system software. The customer or end user couples the mass storage device to the generic computing device in order to load the configuration information into the computing device. After the configuration information is loaded, the computing device is configured for the customer's use. Further features, such as creating customized images, are also provided.

Abstract: A system for calculating analytics uses a relational database to store inputs, calculates results, and stores them in cache. The system also includes an access layer that provides a unified view of the data in server. A dynamic access layer is generated at runtime to run an analytic to provide a flexible framework for creating business logic.

Abstract: Label contention in a label switched network is resolved by applying a contention resolution scheme that reconciles policies for handling unidirectional and bidirectional label switched path setup.

Abstract: Antibodies that bind human interleukin-18 (hIL-18) are provided, in particular antibodies that bind epitope(s) of human IL-18. The antibodies can be, for example, entirely human antibodies, recombinant antibodies, or monoclonal antibodies. Preferred antibodies have high affinity for hIL-18 and neutralize hIL-18 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Method of making and method of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hIL-18 and for inhibiting hIL-18 activity, e.g., in a human subject suffering from a disorder in which hIL-18 activity is detrimental.

Abstract: Embodiments of the present invention are directed to a gas distribution system which distributes the gas more uniformly into a process chamber. In one embodiment, a gas distribution system comprises a gas ring including an outer surface and an inner surface, and a gas inlet disposed at the outer surface of the gas ring. The gas inlet is fluidicly coupled with a first channel which is disposed between the outer surface and the inner surface of the gas ring. A plurality of gas outlets are distributed over the inner surface of the gas ring, and are fluidicly coupled with a second channel which is disposed between the outer surface and the inner surface of the gas ring. A plurality of orifices are fluidicly coupled between the first channel and the second channel.

Abstract: Antibodies that bind human interleukin-18 (hIL-18) are provided, in particular antibodies that bind epitope(s) of human IL-18. The antibodies can be, for example, entirely human antibodies, recombinant antibodies, or monoclonal antibodies. Preferred antibodies have high affinity for hIL-18 and neutralize hIL-18 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Method of making and method of using the antibodies of the invention are also provided. The antibodies, or antibody portions, of the invention are useful for detecting hIL-18 and for inhibiting hIL-18 activity, e.g., in a human subject suffering from a disorder in which hIL-18 activity is detrimental.

Abstract: A system for calculating analytics uses a relational database to store inputs, calculates results, and stores them in cache. The system also includes an access layer that provides a unified view of the data in server. A dynamic access layer is generated at runtime to run an analytic to provide a flexible framework for creating business logic.

Abstract: A method of selecting a restoration path in a mesh telecommunication network is disclosed that advantageously is practical and flexible and may be pre-computed along with a service connection path during the setup of the connection. The information used to select the restoration path can be advantageously distributed among nodes in the network.

Abstract: Systems and methods are described that provide a distributed restoration signaling protocol for shared mesh restoration with standbys for transparent optical networks.

Abstract: A functional electrical stimulation system (30) for moving at least a portion of a body of a subject (12), such as their legs (13, 13a). The system is adapted to monitor its performance and/or the outcome of the provision of stimulation to the subject (12) and assess whether the body portion is showing evidence of fatigue. The system (30) comprises a stimulator (35) that can provide a plurality of sets of functional electrical stimulation to the legs, one or more transducers (60, 61) that outputs signals representative of the movement made by the legs in response to the functional electrical stimulation provided thereto, and a control means (32). The control means (32) receives and processes the signals output by the transducers (60, 61) and includes a comparator adapted to compare the output signals of the transducers resulting from the provision of two or more substantially equivalent sets of electrical stimulation to the legs and provide an output indicative of variation in the movement.

Abstract: A system and method for routing packet traffic is disclosed. A system that incorporates teachings of the present disclosure may include, for example, a router having a routing element that routes packet traffic according to Internal Gateway Protocol (IGP) weights that prevent multicast packet traffic and unicast packet traffic from occupying a common unidirectional link. Other embodiments are disclosed.

Abstract: Human antibodies, preferably recombinant human antibodies, that specifically bind to human interleukin-12 (hIL-12) are disclosed. Preferred antibodies have high affinity for hIL-12 and neutralize hIL-12 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. The antibodies, or antibody portions, of the invention are useful for detecting hIL-12 and for inhibiting hIL-12 activity, e.g., in a human subject suffering from a disorder in which hIL-12 activity is detrimental. Nucleic acids, vectors and host cells for expressing the recombinant human antibodies of the invention, and methods of synthesizing the recombinant human antibodies, are also encompassed by the invention.

Abstract: The present invention provides a method and a system for determining a promise date for a demand whose supply depends on constraints in a business environment. According to the present invention, information related to the business environment is stored within a data storage means. The present invention provides a processor coupled to the data storage means from which it requests and retrieves data. The processor also determines a plan date for each supply in the supply structure. The plan date is determined, from a highest level to a lowest level in the supply structure, based on existing and planned supply in the supply structure. After determining a plan date, the processor determines an available date for each supply in the supply structure. The available date is determined, from the lowest level to the highest level in the supply structure, based on the availability of each supply in the supply structure, and the plan date determined for each supply.

Abstract: Systems and methods to distribute media content are provided. A particular method includes receiving first link weighting factors and second link weighting factors at a router of a node of a multicast network and determining a primary path to a next hop node based on the first link weighting factors. Additionally, the method includes determining a backup path from a router of the primary path to the next hop node based on the second link weighting factors. The backup path does not overlap any primary path between two nodes of the network. Further, the method includes receiving a data packet from a parent node and routing a copy of the data packet from the router to the next hop node via the backup path, when a network link related to the router has failed. The method also includes routing data packets via a re-configured multicast tree that excludes the failed link.