Patents by Inventor Robert E. Cohen

Robert E. Cohen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9506846
    Abstract: A microfluidic device for manipulating particles can include a substrate and one or more obstacles, each obstacle comprising a plurality of aligned nanostructures including a plurality of nanoparticles or a plurality of polymer layers, or a combination thereof. The obstacle on a substrate can be forests with intra-carbon nanotube spacing ranging between 5-100 nm for isolation of particles such as very small viruses and proteins.
    Type: Grant
    Filed: August 8, 2013
    Date of Patent: November 29, 2016
    Assignees: Massachusetts Institute of Technology, The General Hospital Corporation
    Inventors: Michael Rubner, Brian L. Wardle, Robert E. Cohen, Mehmet Toner, Fabio Fachin
  • Patent number: 9469083
    Abstract: Inverted Nanocone Structures and Its Fabrication Process. The method of fabricating nanotextured structures includes making a master mold having an array of tapered structures to be replicated. The master mold is pressed into a curable polymer supported on a substrate and the polymer is cured. Thereafter, the mold is detached from the cured polymer to form the nanotextured structure.
    Type: Grant
    Filed: July 1, 2013
    Date of Patent: October 18, 2016
    Assignee: Massachusetts Institute of Technology
    Inventors: Hyungryul Choi, Jeong-gil Kim, Kyoo Chul Park, Robert E. Cohen, Gareth H. McKinley, George Barbastathis
  • Patent number: 9352258
    Abstract: A structure for collecting liquid droplets from an aerosol can have a structure and properties that are selected for efficient liquid collection. In particular, the strand radius and spacing of a mesh, and a material for coating the mesh, can be selected to provide efficient collection of water droplets from fog.
    Type: Grant
    Filed: January 10, 2014
    Date of Patent: May 31, 2016
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Kyoo-Chul Park, Shreerang S. Chhatre, Gareth H. McKinley, Robert E. Cohen
  • Publication number: 20150315562
    Abstract: Uniform, functional polymer patches can be attached to a fraction of the surface area of living individual cells. These surface-modified cells remain viable after attachment of the functional patch. The patch does not completely occlude the cellular surface from the surrounding environment. Functional payloads carried by the patch may include, for example, drugs or other small molecules, peptides, proteins, thermally responsive polymers, and nanoparticles, or any other material that can be incorporated in a polymer patch of subcellular dimensions. The patch can include one or more polyelectrolyte multilayers (PEMs).
    Type: Application
    Filed: November 2, 2012
    Publication date: November 5, 2015
    Applicant: Massachusetts Institute of Technology
    Inventors: Albert J. Swiston, Michael F. Rubner, Robert E. Cohen, Darrell J. Irvine
  • Patent number: 9011970
    Abstract: A process for making an article having anti-fog properties.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: April 21, 2015
    Assignee: Essilor International
    Inventors: Haipeng Zheng, Michael Rubner, Nuerxiati Nueraji, Robert E. Cohen
  • Patent number: 8986848
    Abstract: A hydrophilic coating can be applied to virtually any surface to produce a long-lasting, durable antifog effect. The coating includes a molecular-level blend of hydrophilic polymers. The coating can be assembled using a layer-by-layer assembly process.
    Type: Grant
    Filed: June 2, 2010
    Date of Patent: March 24, 2015
    Assignee: Massachusetts Institute of Technology
    Inventors: Nuerxiati Nueraji, Albert J. Swiston, Michael F. Rubner, Robert E. Cohen
  • Publication number: 20140336039
    Abstract: Titania-based porous nanoparticle coatings are mechanically robust, with low haze, which exhibit short time scales for decomposition of fingerprint oils under ultraviolet light. The mechanism by which a typical dactylogram is consumed combines wicking of the sebum into the nanoporous titania structure followed by photocatalytic degradation. These TiO2 nanostructured surfaces are also anti-fogging, anti-bacterial, and compatible with flexible glass substrates and remain photocatalytically active in natural sunlight.
    Type: Application
    Filed: May 9, 2014
    Publication date: November 13, 2014
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Robert E. COHEN, Michael F. RUBNER, Gareth H. MCKINLEY, George BARBASTATHIS, Hyungryul Johnny CHOI, Kyoo Chul PARK, Hyomin LEE
  • Publication number: 20140322725
    Abstract: The present invention provides compositions comprising chimeric polypeptides that bind to free ubiquitin proteins or free ubiquitin-like proteins with high affinity, as well as chimeric polypeptides that bind to both free and conjugated ubiquitin proteins or free and conjugated ubiquitin-like proteins, and methods of using the chimeric polypeptides to determine the amount of free or total ubiquitin or free or total ubiquitin-like proteins in various types of samples.
    Type: Application
    Filed: April 30, 2014
    Publication date: October 30, 2014
    Applicant: Colorado State University Research Foundation
    Inventors: Robert E. Cohen, Yun-Seok Choi
  • Publication number: 20140190352
    Abstract: A structure for collecting liquid droplets from an aerosol can have a structure and properties that are selected for efficient liquid collection. In particular, the strand radius and spacing of a mesh, and a material for coating the mesh, can be selected to provide efficient collection of water droplets from fog.
    Type: Application
    Filed: January 10, 2014
    Publication date: July 10, 2014
    Inventors: Kyoo-Chul Park, Shreerang S. Chhatre, Gareth H. McKinley, Robert E. Cohen
  • Publication number: 20140127774
    Abstract: Uniform, functional polymer patches can be attached to a fraction of the surface area of living individual cells. These surface-modified cells remain viable after attachment of the functional patch. The patch does not completely occlude the cellular surface from the surrounding environment. Functional payloads carried by the patch may include, for example, drugs or other small molecules, peptides, proteins, thermally responsive polymers, and nanoparticles, or any other material that can be incorporated in a polymer patch of subcellular dimensions. The patch can include one or more polyelectrolyte multilayers (PEMs).
    Type: Application
    Filed: November 2, 2012
    Publication date: May 8, 2014
    Applicant: Massachusetts Institute of Technology
    Inventors: Albert J. Swiston, Michael F. Rubner, Robert E. Cohen, Darrell J. Irvine
  • Patent number: 8709582
    Abstract: An optical article comprising a substrate and on at least one face of the substrate a multilayered antireflecting coating functioning in an interferential manner having antifog properties, said antireflecting coating including a last layer with a refractive index n?1.55 and a physical thickness of 120 nm or less directly deposited on a high refractive index layer (HI layer) having a refractive index n>1.55, and a thickness of less than 500 nm.
    Type: Grant
    Filed: July 30, 2010
    Date of Patent: April 29, 2014
    Assignee: Essilor International
    Inventors: Haipeng Zheng, Michael Rubner, Nuerxiati Nueraji, Robert E. Cohen
  • Patent number: 8701927
    Abstract: A superhydrophilic thin film is formed on a metal surface of a boiler vessel to alter the wettability and roughness of the surface, which, in turn, changes the boiling behavior at the surface. The superhydrophilic film is formed by depositing a layer of a first ionic species on the surface from a solution. A second ionic species having a charge opposite to the that of the first ionic species is then deposited from solution onto the surface to produce a bilayer of the first ionic species and the oppositely charged second ionic species. The depositions are then repeated to form a plurality of bilayers, on top of the preceding bilayer. The bilayers are then heated, leaving the second ionic species on the metal surface to form a superhydrophilic film.
    Type: Grant
    Filed: February 10, 2010
    Date of Patent: April 22, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Michael F. Rubner, Jacopo Buongiorno, Lin-wen Hu, Eric Christopher Forrest, Erik Howard Williamson, Robert E. Cohen
  • Publication number: 20140079601
    Abstract: A microfluidic device for manipulating particles can include a substrate and one or more obstacles, each obstacle comprising a plurality of aligned nanostructures including a plurality of nanoparticles or a plurality of polymer layers, or a combination thereof. The obstacle on a substrate can be forests with intra-carbon nanotube spacing ranging between 5-100 nm for isolation of particles such as very small viruses and proteins.
    Type: Application
    Filed: August 8, 2013
    Publication date: March 20, 2014
    Inventors: Michael Rubner, Brian L. Wardle, Robert E. Cohen, Mehmet Toner, Fabio Fachin
  • Patent number: 8637141
    Abstract: A superhydrophilic coating can be antireflective and antifogging. The coating can remain antireflective and antifogging for extended periods. The coating can have a graded refractive index. The coating for wafer-level optics can be for targeted capillary condensation in nanoparticle containing reflow-compatible coatings.
    Type: Grant
    Filed: May 28, 2009
    Date of Patent: January 28, 2014
    Assignee: Massachusetts Institute of Technology
    Inventors: Zekeriyya Gemici, Michael F. Rubner, Robert E. Cohen
  • Publication number: 20140010994
    Abstract: Inverted Nanocone Structures and Its Fabrication Process. The method of fabricating nanotextured structures includes making a master mold having an array of tapered structures to be replicated. The master mold is pressed into a curable polymer supported on a substrate and the polymer is cured. Thereafter, the mold is detached from the cured polymer to form the nanotextured structure.
    Type: Application
    Filed: July 1, 2013
    Publication date: January 9, 2014
    Applicant: Massachusetts Institute of Technology
    Inventors: Hyungryul Choi, Jeong-gil Kim, Kyoo Chul Park, Robert E. Cohen, Gareth H. McKinley, George Barbastathis
  • Patent number: 8446666
    Abstract: The present invention discloses a non-quarter wave multilayer structure having a plurality of alternating low index of refraction material stacks and high index of refraction material stacks. The plurality of alternating stacks can reflect electromagnetic radiation in the ultraviolet region and a narrow band of electromagnetic radiation in the visible region. The non-quarter wave multilayer structure, i.e. nLdL?nHdH??0/4, can be expressed as [A 0.5 qH pL(qH pL)N 0.5 qH G], where q and p are multipliers to the quarter-wave thicknesses of high and low refractive index material, respectively, H is the quarter-wave thickness of the high refracting index material; L is the quarter-wave thickness of the low refracting index material; N represents the total number of layers between bounding half layers of high index of refraction material (0.5 qH); G represents a substrate and A represents air.
    Type: Grant
    Filed: May 18, 2009
    Date of Patent: May 21, 2013
    Assignees: Toyota Motor Engineering & Manufacturing North America, Inc., Toyota Motor Corporation, Massachusetts Institute of Technology
    Inventors: Pinar Kurt, Debasish Banerjee, Robert E. Cohen, Michael Rubner, Masahiko Ishii, Minjuan Zhang
  • Patent number: 8323637
    Abstract: Uniform, functional polymer patches can be attached to a fraction of the surface area of living individual cells. These surface-modified cells remain viable after attachment of the functional patch. The patch does not completely occlude the cellular surface from the surrounding environment. Functional payloads carried by the patch may include, for example, drugs or other small molecules, peptides, proteins, thermally responsive polymers, and nanoparticles, or any other material that can be incorporated in a polymer patch of subcellular dimensions. The patch can include one or more polyelectrolyte multilayers (PEMs).
    Type: Grant
    Filed: April 9, 2009
    Date of Patent: December 4, 2012
    Assignee: Massachusetts Institute of Technology
    Inventors: Albert J. Swiston, Michael F. Rubner, Robert E. Cohen, Darrell J. Irvine
  • Patent number: 8313798
    Abstract: A process for fabricating a structural color having ultraviolet reflectance is provided. The process includes providing an atomizing nozzle, a first nanoparticle solution and a second nanoparticle solution. The atomizing nozzle is used to spray a plurality of first nanoparticle solution layers, the plurality of first nanoparticle layers forming a low index of refraction stack. In some instances, a polymer solution can be sprayed before and/or after the spraying of each first nanoparticle solution layer. The atomizing nozzle is also used to spray a plurality of second nanoparticle solution layers, the plurality of second nanoparticle layers form a high index of refraction stack. Similar to the first nanoparticle solution layers, a polymer solution can be sprayed before and/or after the spraying of each second nanoparticle solution layer.
    Type: Grant
    Filed: September 29, 2010
    Date of Patent: November 20, 2012
    Assignees: Toyota Motor Engineering & Manufacturing North America, Inc., Massachusetts Institute of Technology
    Inventors: Grinia Michelle Nogueira, Debasish Banerjee, Michael F. Rubner, Robert E. Cohen
  • Patent number: 8241698
    Abstract: One aspect of the present invention relates to an implantable medical device comprising a surface coated with a polyelectrolyte multilayer, wherein said surface is glass, metal, plastic, polymer, or fiberglass. Another aspect of the present invention involves a method of preparing a PEM-coated implantable medical device, comprising the step of applying a film to a surface of an implantable medical device, wherein said film comprises a polyelectrolyte multilayer and said surface is glass, metal, plastic, polymer, or fiberglass.
    Type: Grant
    Filed: August 6, 2007
    Date of Patent: August 14, 2012
    Assignee: Massachusetts Institute of Technology
    Inventors: Robert E. Cohen, Prem V. Pavoor, Anuj Bellare, Brian P. Gearing
  • Publication number: 20120160362
    Abstract: This invention relates generally to articles, devices, and methods for gas hydrate mitigation in deep-sea drilling applications. In certain embodiments, hydrate-phobic surfaces are provided that ensure passive enhancement of flow assurance and prevention of catastrophic failures in deep-sea oil and gas operations.
    Type: Application
    Filed: August 25, 2011
    Publication date: June 28, 2012
    Applicant: Massachusetts Institute of Technology
    Inventors: J. David Smith, Kripa K. Varanasi, Gareth H. McKinley, Robert E. Cohen, Adam J. Meuler, Harrison L. Bralower