Abstract: The present invention relates to Fc variants having increased affinity for Fc?RIIc, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: The present invention relates to Fc variants having decreased affinity for Fc?RIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: The present invention relates to Fc variants having decreased affinity for Fc?RIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: Optical apparatus for a display device. The optical apparatus comprises a cavity, and a first fluid (14) and a second fluid (16), held within the cavity, which are immiscible with each other. The first and second fluids are separated from each other by a meniscus (28) having a peripheral edge (30). The optical apparatus further comprises a fluid motion control system arranged to control movement of the first and second fluids within the cavity using electrostatic forces, and a first surface (26) and a second surface (21). The first surface has a different wettability for the first fluid than for the second surface. The first and second surfaces are arranged in the cavity to determine, upon activation of the fluid motion control system, a motion of the fluids within the cavity which has a preferential initiation at a first part (32) of the peripheral edge.

Abstract: The invention relates to large area electrodes suitable for use in a fetal heart rate monitoring systems. The electrode comprises: a cutaneous gel contact (10) for sensing fetal electrocardiogram signals from a human pregnant subject; an electrical conductor (12) electrically connected to the gel contact (10) so as to define a first electrical contact region; a connector (14) in electrical contact with the electrical conductor (12) for connection to a lead wire; and a substructure (16) for attachment to a human pregnant subject. The gel contact (10) and the electrical conductor (12) are arranged on the substructure (16) to allow a contact surface (11) of the gel contact (10) to be in electrical communication with the skin of a human pregnant subject to define a second electrical contact region. The second electrical contact region has an area greater than 370 square millimeters.

Abstract: Power adapters for providing power to accessory devices in refrigerated containers are provided herein. The power adapter comprises a first connector communicatively coupled with a plurality of conductors; a second connector communicatively coupled with two or more of the plurality of conductors; and a shunt communicatively coupled with at least four of the plurality of conductors and configured to provide power to an accessory output in response to the accessory connection being communicatively coupled with an accessory device.

Abstract: The present invention relates to Fc variants having decreased affinity for Fc?RIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: Included are embodiments for enhanced carrier suppression. One embodiment of a circuit includes a mixer that receives a cover sequence, the cover sequence including transition data from a first signal and a second signal. The mixer may be configured to generate a modulated cover sequence by modulating a radio frequency (RF) carrier with the cover sequence. Some embodiments also include a modulator that is communicatively coupled to the mixer. The modulator may be configured to receive and modulate an altered version of the first signal and an altered version of the second signal. The modulator may additionally receive the modulated cover sequence as an RF carrier input and generate an RF output by modulating the modulated cover sequence with the altered version of the first signal and the altered version of the second signal.

Abstract: A system for distributing perishable goods includes a remote central control station, a plurality of local control units, and a plurality of mobile storage containers. By wirelessly transmitting information between the remote central control system and local control units, controlled conditions within the associated mobile storage containers can be optimized to preserve the perishable goods within the containers during lengthy transport trips.

Abstract: The present invention relates to Fc variants having decreased affinity for Fc?RIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: The present invention relates to Fc variants having decreased affinity for Fc?RIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: The present invention relates to a method for making an electrowetting display device comprising a plurality of picture elements and a first support plate and a second support plate. Each picture element comprises a space between the first support plate and the second support plate. The method comprises the steps of: providing the first support plate with an electrode structure; arranging an insulating layer on the electrode structure, the insulating layer having a thickness and a hydropobic surface facing the space; temporarily applying an electric field across the thickness of the insulating layer to reduce permanently the hydrophobicity of a predetermined area of the surface. The invention further relates to an electrowetting display device and a use of an area of reduced hydrophobicity in an electrowetting device.

Abstract: The present invention relates to Fc variants having decreased affinity for Fc?RIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: The present invention relates to Fc variants having increased affinity for Fc?RIIc, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: The present invention relates to Fc variants having decreased affinity for Fc?RIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: Enterprise information handling system storage solutions are configured automatically through a graphical user interface that accepts storage device and storage topology selections from an end user to automatically present a graphical image depicting interconnection devices that interface the storage devices. For example, cables with a color selected by the end user are depicted interfacing storage devices with the selected color. In one embodiment, switches are automatically selected and depicted for the storage devices and storage topology selected by the end user.

Abstract: The present invention relates to Fc variants having decreased affinity for Fc?RIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: The present invention relates to Fc variants having decreased affinity for Fc?RIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: The present invention relates to Fc variants having decreased affinity for Fc?RIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: The present invention relates to a variant Fc region comprising an amino acid substitution at position 238 of the Fc region as compared to a human parent Fc region, wherein the variant Fc region comprises a 238D substitution, wherein the variant Fc region binds Fc?RIIb with increased binding affinity compared to a human parent Fc region.