Abstract: The present invention relates to Fc variants having decreased affinity for Fc?RIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: A display device comprising picture elements, which are constituted by electrowetting elements having at least one first fluid and a second fluid immiscible with each other within a space between a first support plate and a second support plate, the second fluid being electro-conductive or polar. The first fluid in each element is at the side of the first support plate confined by element walls, and the second fluid is shared by a plurality of picture elements, characterized by a preventer for preventing first fluid portions from being expelled from its confinement when forces other than electrowetting forces are exerted on this fluid.

Abstract: The present invention relates to Fc variants having increased affinity for Fc?RIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: Included are embodiments for enhanced carrier suppression. One embodiment of a circuit includes a mixer that receives a cover sequence, the cover sequence including transition data from a first signal and a second signal. The mixer may be configured to generate a modulated cover sequence by modulating a radio frequency (RF) carrier with the cover sequence. Some embodiments also include a modulator that is communicatively coupled to the mixer. The modulator may be configured to receive and modulate an altered version of the first signal and an altered version of the second signal. The modulator may additionally receive the modulated cover sequence as an RF carrier input and generate an RF output by modulating the modulated cover sequence with the altered version of the first signal and the altered version of the second signal.

Abstract: The present invention relates to a method for making an electrowetting display device comprising a plurality of picture elements and a first support plate and a second support plate. Each picture element comprises a space between the first support plate and the second support plate. The method comprises the steps of: providing the first support plate with an electrode structure; arranging an insulating layer on the electrode structure, the insulating layer having a thickness and a hydropobic surface facing the space; temporarily applying an electric field across the thickness of the insulating layer to reduce permanently the hydrophobicity of a predetermined area of the surface. The invention further relates to an electrowetting display device and a use of an area of reduced hydrophobicity in an electrowetting device.

Abstract: Power adapters for providing power to accessory devices in refrigerated containers are provided herein. The power adapter comprises a first connector communicatively coupled with a plurality of conductors; a second connector communicatively coupled with two or more of the plurality of conductors; and a shunt communicatively coupled with at least four of the plurality of conductors and configured to provide power to an accessory output in response to the accessory connection being communicatively coupled with an accessory device.

Abstract: Fetal behavior is monitored by receiving ECG data from a set of electrodes attached to a material body. A waveform pre-processor identifies a succession of fetal ECG complex waveforms within the received data and a waveform processor determines differences in the processor succession of fetal ECG complex waveforms over time. An event logger determines from the determined differences a number of fetal movements during the period of time. Fetal spatial presentation and/or position within the uterus may also be determined from fetal ECG data acquired from a plurality of electrodes positioned on the maternal abdomen in a predetermined configuration. A number of fetal ECG complex waveforms are identified within the data, and each of the waveforms is compared with a set of predetermined fetal ECG complex templates ascribed to the predetermined electrode configuration to determine a template that best matches the identified fetal ECG waveforms.

Abstract: An apparatus and method for detecting uterine activity uses cutaneous electrodes on the maternal abdomen to obtain electrophysiological signals that can be used to obtain fetal and maternal heart rate. The apparatus includes a first input for receiving electrical signals from the cutaneous electrodes and a second input for receiving movement signals indicative of a movement of the maternal body from a movement detector. A signal processor separates a uterine electromyogram signal from fetal and maternal heart rate signals and filters out motion artefacts from the electromyogram using the movement signals. An output presents electrohysterogram (EHG) data from the uterine electromyogram signal.

Abstract: The present invention relates to reducing backflow in an electrowetting element for modifying a radiation beam characteristic. The electrowetting element comprises a first and a second fluid which are immiscible with each other and are switchable between a first configuration and a second configuration by application of a voltage across at least one of the first and second fluids. There is a tendency for backflow of the second fluid from the first configuration to the second configuration when the second fluid is switched to be provided in the first configuration. The electrowetting element comprises a backflow reducer arranged for reducing the backflow of the second fluid from the first configuration to the second configuration when the second fluid is switched to be provided in the first configuration.

Abstract: The present invention relates to optimized Fc variants, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: The invention relates to a method of driving an electrowetting display device including a display element, the display element having an electrode for applying a voltage and providing a display state in response to a signal level of the voltage. The method comprises the following subsequent steps for maintaining a display state of the display element: (1) applying a first signal level (Va) during a first period (t1 t2) for the display state; (2) applying a second signal level (0) during a second period (t2-t3); and (3) applying the first signal level during a third period (t3-t4). The first period is longer than 1 ms and the first period plus the third period is longer than five times the second period.

Abstract: The spatial position of a fetus within the womb is determined and monitored through analysis of ECG waveform data received from a set of electrodes that are attached to a maternal abdomen in a predetermined configuration. The waveform is compared with a set of predefined stored templates to determine the position of the fetus. An event logger may determine the number of fetal movements during a period of time.

Abstract: The invention relates to large area electrodes suitable for use in a fetal heart rate monitoring systems. The electrode comprises: a cutaneous gel contact (10) for sensing fetal electrocardiogram signals from a human pregnant subject; an electrical conductor (12) electrically connected to the gel contact (10) so as to define a first electrical contact region; a connector (14) in electrical contact with the electrical conductor (12) for connection to a lead wire; and a substructure (16) for attachment to a human pregnant subject. The gel contact (10) and the electrical conductor (12) are arranged on the substructure (16) to allow a contact surface (11) of the gel contact (10) to be in electrical communication with the skin of a human pregnant subject to define a second electrical contact region. The second electrical contact region has an area greater than 370 square millimetres.

Abstract: In a reflective a display device based on layer break up or layer displacement having at least two different states, in which one of the fluids (5) e.g. oil in a first state adjoins at least a first support plate (3) and in the second state the other fluid (6) at least partly adjoins the first support plate, in which picture elements are separated by areas (13) having a hydrophilic surface dyes (or sometimes pigments) are added to the oil (usually hydrocarbon but also possibly silicone or fluorocarbon), to provide sufficient optical intensity.

Abstract: A dye for a fluid of an electrowetting element, the dye having a general formula selected from the group consisting of: wherein Q has the general formula: -Het1R1 or -Het1R1R2; V has the general formula: -Het2R3 or -Het2R3R4; Het1 and Het2 are heteroatoms; R1 and R3 are H; R2 and R4 are any functional group; T and U are any functional group; W, X, Y and Z are H or an alkyl group; and F, G, L and M are H or an alkyl group, and with the proviso that the dye does not have the general formula: The present invention further relates to a fluid comprising a dye of the present invention, an electrowetting element and an optical display device comprising the fluid, and a use of the dye to reduce photo-bleaching.

Abstract: A display device based on e.g. oil layer break up or oil layer displacement having at least two different states, having a wall (13) height which is insignificant compared to the pixel width and also to the typical curvature of the oil interface at the tip of the dosing needle (15), the pixels are dosed without inserting the needle into the pixels. As the dosing needle no longer has to enter the pixel, pixels can be dosed with oil (5) from a relatively large injection needle.

Abstract: A transflective display device has a viewing side (7) and a rear side (8) and comprises a plurality of electrowetting elements (2) having a first support plate (5) facing the viewing side and a second support plate (6) facing the rear side. Each electrowetting element comprises a space (10) between the first support plate and the second support plate and includes a first fluid (11) and a second fluid (12) immiscible with each other. The second fluid absorbs at least a part of the optical spectrum. The position of the second fluid is controllable to cover a predetermined area (30) of the cross-section (29) of the space in the plane of the second support plate. A structured reflector (18) is arranged on the second support plate, comprising within the cross-section an area (33, 34) transparent for light incident from the rear side and an area (35, 36) reflective for light incident from the viewing side.

Abstract: The present invention relates to Fc variants having decreased affinity for Fc?RIIb, methods for their generation, Fc polypeptides comprising optimized Fc variants, and methods for using optimized Fc variants.

Abstract: A display device comprising picture elements, which are constituted by electrowetting elements having at least one first fluid and a second fluid immiscible with each other within a space between a first support plate and a second support plate, the second fluid being electro-conductive or polar. The first fluid in each element is at the side of the first support plate confined by element walls, and the second fluid is shared by a plurality of picture elements, characterised by a preventer for preventing first fluid portions from being expelled from its confinement when forces other than electrowetting forces are exerted on this fluid.

Abstract: Optical apparatus for a display device. The optical apparatus comprises a cavity, and a first fluid (14) and a second fluid (16), held within the cavity, which are immiscible with each other. The first and second fluids are separated from each other by a meniscus (28) having a peripheral edge (30). The optical apparatus further comprises a fluid motion control system arranged to control movement of the first and second fluids within the cavity using electrostatic forces, and a first surface (26) and a second surface (21). The first surface has a different wettability for the first fluid than for the second surface. The first and second surfaces are arranged in the cavity to determine, upon activation of the fluid motion control system, a motion of the fluids within the cavity which has a preferential initiation at a first part (32) of the peripheral edge.