Abstract: A method of forming a series of bags for bulky articles from rolled thermoplastic film and padding element includes arranging a linear, longitudinally traveling queue of layers of film and padding element according to a set of desired bag dimensions and characteristics and controlling the advancement of the queue to make padding element and seal cuts to form the bags. The invention also includes a system for fabricating bags substantially in the manner identified in the method of the present invention, as well as a method of forming seal cuts in which an envelope is first clamped, then sealed and cut by heat and pressure, then allowed to cool before being released.

Abstract: An impeller according to an example of the present invention comprises a hub, and at least one blade supported by the hub. The impeller has a deployed configuration in which the blade extends away from the hub, and a stored configuration in which the impeller is radially compressed, for example by folding the blade towards the hub. The impeller may comprise a plurality of blades, arranged in blade rows, to facilitate radial compression of the blades. The outer edge of a blade may have a winglet, and the base of the blade may have an associated indentation to facilitate folding of the blade.

Abstract: The present invention provides specific peptides identified as having cell adhesion, growth, expression or secretion-enhancing activities. Many of the peptides of the invention may be produced in large quantity by such means as chemical synthesis or recombinant DNA methodology. They may be non-specifically adsorbed, or chemically attached to a surface or, alternatively, formulated in a culture medium to produce the desired effect on cultured cells.

Abstract: A method of forming a series of bags for bulky articles from rolled thermoplastic film and padding element includes arranging a linear, longitudinally traveling queue of layers of film and padding element according to a set of desired bag dimensions and characteristics and controlling the advancement of the queue to make padding element and seal cuts to form the bags. The invention also includes a system for fabricating bags substantially in the manner identified in the method of the present invention, as well as a method of forming seal cuts in which an envelope is first clamped, then sealed and cut by heat and pressure, then allowed to cool before being released.

Abstract: The present invention provides peptides libraries which are useful for rapid identification of biologically active compounds. The invention further provides peptides which include cell-growth affecting peptides and peptides which enhance or inhibit production of cellular proteins. Many of the peptides of the invention may be produced in large quantity by recombinant techniques and formulated in culture medium to produce the desired effect on cultured cells and tissues. Certain of the libraries of the invention and the peptides identified in them are particularly useful in concatemer-based recombinant expression methods.

Abstract: An internal combustion rotary engine includes a housing having an inlet and an outlet and a rotatable rotor centrally mounted within the housing. The rotor includes a plurality of pockets located about its circumference, the rotor further being connected to a rotor shaft. A rotatable elliptical body is disposed in each of the plurality of pockets. Each rotatable elliptical body is coupled to respective planet gears and each respective planet gear is meshed with a centrally disposed fixed sun gear. An ignition source is disposed in each of the plurality of pockets for igniting a fuel/air mixture. During operation of the internal combustion rotary engine, for each 360° rotation of the rotor, each elliptical body rotates through 720°.

Abstract: The present invention provides peptides libraries which are useful for rapid identification of biologically active compounds. The invention further provides peptides which include cell-growth affecting peptides and peptides which enhance or inhibit production of cellular proteins. Many of the peptides of the invention may be produced in large quantity by recombinant techniques and formulated in culture medium to produce the desired effect on cultured cells and tissues. Certain of the libraries of the invention and the peptides identified in them are particularly useful in concatemer-based recombinant expression methods.

Abstract: A method of forming a series of bags for bulky articles from rolled thermoplastic film and padding element includes arranging a linear, longitudinally traveling queue of layers of film and padding element according to a set of desired bag dimensions and characteristics and controlling the advancement of the queue to make padding element and seal cuts to form the bags. The invention also includes a system for fabricating bags substantially in the manner identified in the method of the present invention, as well as a method of forming seal cuts in which an envelope is first clamped, then sealed and cut by heat and pressure, then allowed to cool before being released.

Abstract: The present invention provides specific peptides identified as having cell adhesion, growth, expression or secretion-enhancing activities. Many of the peptides of the invention may be produced in large quantity by such means as chemical synthesis or recombinant DNA methodology. They may be non-specifically adsorbed, or chemically attached to a surface or, alternatively, formulated in a culture medium to produce the desired effect on cultured cells.

Abstract: The present invention provides peptides libraries which are useful for rapid identification of biologically active compounds. The invention further provides peptides which include cell-growth affecting peptides and peptides which enhance or inhibit production of cellular proteins. Many of the peptides of the invention may be produced in large quantity by recombinant techniques and formulated in culture medium to produce the desired effect on cultured cells and tissues. Certain of the libraries of the invention and the peptides identified in them are particularly useful in concatemer-based recombinant expression methods.

Abstract: The present invention provides peptides libraries which are useful for rapid identification of biologically active compounds. The invention further provides peptides which include cell-growth affecting peptides and peptides which enhance or inhibit production of cellular proteins. Many of the peptides of the invention may be produced in large quantity by recombinant techniques and formulated in culture medium to produce the desired effect on cultured cells and tissues. Certain of the libraries of the invention and the peptides identified in them are particularly useful in concatemer-based recombinant expression methods.

Abstract: A method of preparing a pharmaceutical composition is described, comprising 1) atomizing a liquid formulation of a therapeutic agent to produce an atomized formulation; 2) freezing said atomized formulation to form solid particles; and 3) drying said solid particles to produce a powder. Compositions made by the above methods, and methods of using the compositions, are also described.

Abstract: A coupling device for engaging an exchangeable tool support (7) for corotation with a shaft (2) of a motor (1), with the shaft (2) mounting at is driven end a hollow shaft projection (3) for receiving the tool support (7). Alternatively, the tool support (7) can mount the hollow shaft projection for receiving the driven end of the shaft. The shaft (2) and/or the tool support mounts a locking device for securing the tool support (7), and which is actuated by centrifugal force. The coupling device is designed and constructed so as to permit a simple mounting of even heavy tools to the output shaft of the motor, and a reliable connection of the tool and drive.

Abstract: The present invention provides peptides libraries which are useful for rapid identification of biologically active compounds. The invention further provides peptides which include cell-growth affecting peptides and peptides which enhance or inhibit production of cellular proteins. Many of the peptides of the invention may be produced in large quantity by recombinant techniques and formulated in culture medium to produce the desired effect on cultured cells and tissues. Certain of the libraries of the invention and the peptides identified in them are particularly useful in concatemer-based recombinant expression methods.

Abstract: A coupling device for engaging an exchangeable tool support (7) for corotation with a shaft (2) of a motor (1), with the shaft (2) mounting at is driven end a hollow shaft projection (3) for receiving the tool support (7), or the tool support (7) comprising a hollow shaft projection for receiving the driven end of the shaft, and with the shaft (2) and/or the tool support comprising a locking device for securing the tool support (7), is designed and constructed with respect to a simple insertion of also heavy tools and a reliable connection of the tool and drive such that the locking device is actuated by centrifugal force.

Abstract: Methods, apparatus and computer program products are provided for identifying a component of culture medium based on the parameters (e.g, physical, chemical, biological and/or topological characteristics) of compounds from within a compound library. In preferred embodiments, the compound library is a peptide library. Also provided are methods of selecting a compound library from a larger compound space based on whole molecule (i.e., global) parameters of the compounds. Preferably, this method is practiced in conjunction with a method of identifying a component of a culture medium. Further provided are methods of predicting a biological activity of a peptide based on at least one whole molecule parameter of the peptide. This method finds use in methods of drug discovery, identifying components of culture medium, and identifying and/or designing peptides with particular pharmacological or therapeutic activities.

Abstract: The present invention provides specific peptides identified as having cell adhesion, growth, expression or secretion-enhancing activities. Many of the peptides of the invention may be produced in large quantity by such means as chemical synthesis or recombinant DNA methodology. They may be non-specifically adsorbed, or chemically attached to a surface or, alternatively, formulated in a culture medium to produce the desired effect on cultured cells.

Abstract: The invention relates to an immunogenic composition and methods of making and using the composition. The immunogenic composition contains a directing molecule, a stimulant and an immunogen. The stimulant and directing molecule are chemically distinct. The stimulant and immunogen are present in relative amounts to result in an improved immune response relative to that resulting from the immunogen and just one of the directing molecule or stimulant.

Abstract: Methods, apparatus and computer program products are provided for identifying a component of culture medium based on the parameters (e g, physical, chemical, biological and/or topological characteristics) of compounds from within a compound library. In preferred embodiments, the compound library is a peptide library. Also provided are methods of selecting a compound library from a larger compound space based on whole molecule (i.e., global) parameters of the compounds. Preferably, this method is practiced in conjunction with a method of identifying a component of a culture medium. Further provided are methods of predicting a biological activity of a peptide based on at least one whole molecule parameter of the peptide. This method finds use in methods of drug discovery, identifying components of culture medium, and identifying and/or designing peptides with particular pharmacological or therapeutic activities.

Abstract: The present invention provides methods for pretreating water for desalination. According to one embodiment of the invention, a method for pretreating water is provided comprising simultaneously emitting acoustic energy to cause cavitation and light at a wavelength of 200 nm or less at the water. The light causes ozone to be generated. The ozone acts as an oxidizing and anti-foaming agent to sterilize the water. The ozone also inhibits the amalgamation of soft scales in the water. The inventors have also discovered that this method is more efficient than separately applying the acoustic energy and the light to the water. As a result, this method requires on average 25-30% less energy than separately applying the acoustic energy and light. The ozone is preferably removed or destroyed in the water after this method is performed. The ozone may be destroyed by emitting pulsed light at a wavelength of greater than about 200 nm at the water.