Patents by Inventor Ronghui Lin

Ronghui Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibodies to aripiprazole and use thereof
    Patent number: 10175257
    Abstract: Disclosed is an antibody which binds to aripiprazole, which can be used to detect aripiprazole in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of aripiprazole, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.
    Type: Grant
    Filed: October 17, 2016
    Date of Patent: January 8, 2019
    Assignee: Janssen Pharmaceutica NV
    Inventors: Eric Hryhorenko, Banumathi Sankaran, Thomas R. DeCory, Theresa Tubbs, Linda Colt, Bart M. Remmerie, Rhys Salter, Ronghui Lin
  • Haptens of aripiprazole
    Patent number: 10166296
    Abstract: The invention relates to compounds of Formula I, wherein R1, R2, and R3 are defined in the specification, useful for the synthesis of novel conjugates and immunogens derived from aripiprazole. The invention also relates to conjugates of an aripiprazole hapten and a protein.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: January 1, 2019
    Assignee: Janssen Pharmaceutica NV
    Inventors: Ronghui Lin, Rhys Salter, Thomas R. DeCory, Eric Hryhorenko, Bart M. Remmerie, Banumathi Sankaran
  • Substituted Pyridine Derivatives Useful As C-FMS Kinase Inhibitors
    Publication number: 20180346454
    Abstract: The present invention is directed to substituted pyridine derivatives, pharmaceutical compositions containing said derivatives and the use of said derivatives in the treatment of disorders mediated by c-fms kinase. The present invention is further directed to a process for the preparation of said substituted pyridine derivatives.
    Type: Application
    Filed: August 13, 2018
    Publication date: December 6, 2018
    Inventors: Jie CHEN, Matthew DONAHUE, Heng-Keang LIM, Ronghui LIN, Rhys SALTER, Jiejun WU, Yong GONG
  • Substituted pyridine derivatives useful as c-fms kinase inhibitors
    Patent number: 10071991
    Abstract: The present invention is directed to substituted pyridine derivatives, pharmaceutical compositions containing said derivatives and the use of said derivatives in the treatment of disorders mediated by c-fms kinase. The present invention is further directed to a process for the preparation of said substituted pyridine derivatives.
    Type: Grant
    Filed: February 23, 2017
    Date of Patent: September 11, 2018
    Assignee: Janssen Pharmaceutica NV
    Inventors: Jie Chen, Matthew Donahue, Heng-Keang Lim, Ronghui Lin, Rhys Salter, Jiejun Wu, Yong Gong
  • ANTIBODIES TO ARIPIPRAZOLE HAPTENS AND USE THEREOF
    Publication number: 20180149637
    Abstract: Disclosed is an antibody which binds to aripiprazole, which can be used to detect aripiprazole in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of aripiprazole, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.
    Type: Application
    Filed: March 30, 2017
    Publication date: May 31, 2018
    Applicant: Janssen Pharmaceutica NV
    Inventors: Eric Hryhorenko, Banumathi Sankaran, Thomas R. DeCory, Theresa Tubbs, Linda Colt, Bart M. Remmerie, Rhys Salter, Ronghui Lin
  • HAPTENS OF ARIPIPRAZOLE
    Publication number: 20180117169
    Abstract: The invention relates to compounds of Formula I, wherein R1, R2, and R3 are defined in the specification, useful for the synthesis of novel conjugates and immunogens derived from aripiprazole. The invention also relates to conjugates of an aripiprazole hapten and a protein.
    Type: Application
    Filed: October 20, 2017
    Publication date: May 3, 2018
    Applicant: Janssen Pharmaceutica NV
    Inventors: Ronghui Lin, Rhys Salter, Thomas R. DeCory, Eric Hryhorenko, Bart Remmerie, Banumathi Sankaran
  • Haptens of aripiprazole
    Patent number: 9795685
    Abstract: The invention relates to compounds of Formula I, wherein R1, R2, and R3 are defined in the specification, useful for the synthesis of novel conjugates and immunogens derived from aripiprazole. The invention also relates to conjugates of an aripiprazole hapten and a protein.
    Type: Grant
    Filed: November 3, 2016
    Date of Patent: October 24, 2017
    Assignee: JANSSEN PHARMACEUTICA NV
    Inventors: Ronghui Lin, Rhys Salter, Thomas R. DeCory, Eric Hryhorenko, Bart M. Remmerie, Banumathi Sankaran
  • Antibodies to Aripiprazole Haptens and Use Thereof
    Publication number: 20170204198
    Abstract: Disclosed is an antibody which binds to aripiprazole, which can be used to detect aripiprazole in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of aripiprazole, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.
    Type: Application
    Filed: March 30, 2017
    Publication date: July 20, 2017
    Applicant: Janssen Pharmaceutica NV
    Inventors: Eric Hryhorenko, Banumathi Sankaran, Thomas R. DeCory, Theresa Tubbs, Linda Colt, Bart M. Remmerie, Rhys Salter, Ronghui Lin
  • SUBSTITUTED PYRIDINE DERIVATIVES USEFUL AS C-FMS KINASE INHIBITORS
    Publication number: 20170158678
    Abstract: The present invention is directed to substituted pyridine derivatives, pharmaceutical compositions containing said derivatives and the use of said derivatives in the treatment of disorders mediated by c-fms kinase. The present invention is further directed to a process for the preparation of said substituted pyridine derivatives.
    Type: Application
    Filed: February 23, 2017
    Publication date: June 8, 2017
    Inventors: Jie CHEN, Matthew DONAHUE, Heng-Keang LIM, Ronghui LIN, Rhys SALTER, Jiejun WU, Yong GONG
  • Substituted pyridine derivatives useful as C-FMS kinase inhibitors
    Patent number: 9611259
    Abstract: The present invention is directed to substituted pyridine derivatives, pharmaceutical compositions containing said derivatives and the use of said derivatives in the treatment of disorders mediated by c-fms kinase. The present invention is further directed to a process for the preparation of said substituted pyridine derivatives.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: April 4, 2017
    Assignee: Janssen Pharmaceutica NV
    Inventors: Jie Chen, Matthew Donahue, Heng-Keang Lim, Ronghui Lin, Rhys Salter, Jiejun Wu, Yong Gong
  • Antibodies to aripiprazole haptens and use thereof
    Patent number: 9611332
    Abstract: Disclosed is an antibody which binds to aripiprazole, which can be used to detect aripiprazole in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of aripiprazole, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.
    Type: Grant
    Filed: August 20, 2013
    Date of Patent: April 4, 2017
    Assignee: Janssen Pharmaceutica NV
    Inventors: Eric Hryhorenko, Banumathi Sankaran, Thomas R. DeCory, Theresa Tubbs, Linda Colt, Bart M Remmerie, Rhys Salter, Ronghui Lin
  • HAPTENS OF ARIPIPRAZOLE
    Publication number: 20170072061
    Abstract: The invention relates to compounds of Formula I, wherein R1, R2, and R3 are defined in the specification, useful for the synthesis of novel conjugates and immunogens derived from aripiprazole. The invention also relates to conjugates of an aripiprazole hapten and a protein.
    Type: Application
    Filed: November 3, 2016
    Publication date: March 16, 2017
    Applicant: Janssen Pharmaceutica NV
    Inventors: Ronghui Lin, Rhys Salter, Thomas R. Decory, Eric Hryhorenko, Bart M. Remmerie, Banumathi Sankaran
  • ANTIBODIES TO ARIPIPRAZOLE AND USE THEREOF
    Publication number: 20170030936
    Abstract: Disclosed is an antibody which binds to aripiprazole, which can be used to detect aripiprazole in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of aripiprazole, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.
    Type: Application
    Filed: October 17, 2016
    Publication date: February 2, 2017
    Applicant: Janssen Pharmaceutica NV
    Inventors: Eric Hryhorenko, Banumathi Sankaran, Thomas R. DeCory, Theresa Tubbs, Linda Colt, Bart M. Remmerie, Rhys Salter, Ronghui Lin
  • Haptens of aripiprazole
    Patent number: 9504682
    Abstract: The invention relates to compounds of Formula I, wherein R1, R2, and R3 are defined in the specification, useful for the synthesis of novel conjugates and immunogens derived from aripiprazole. The invention also relates to conjugates of an aripiprazole hapten and a protein.
    Type: Grant
    Filed: August 20, 2013
    Date of Patent: November 29, 2016
    Assignee: Janssen Pharmaceutica NV
    Inventors: Ronghui Lin, Rhys Salter, Thomas R. DeCory, Eric Hryhorenko, Bart Remmerie, Banumathi Sankaran
  • Antibodies to aripiprazole and use thereof
    Patent number: 9494607
    Abstract: Disclosed is an antibody which binds to aripiprazole, which can be used to detect aripiprazole in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of aripiprazole, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.
    Type: Grant
    Filed: August 20, 2013
    Date of Patent: November 15, 2016
    Assignee: Janssen Pharmaceutica NV
    Inventors: Eric Hryhorenko, Banumathi Sankaran, Thomas R. DeCory, Theresa Tubbs, Linda Colt, Bart M. Remmerie, Rhys Salter, Ronghui Lin
  • SUBSTITUTED PYRIDINE DERIVATIVES USEFUL AS C-FMS KINASE INHIBITORS
    Publication number: 20160016942
    Abstract: The present invention is directed to substituted pyridine derivatives, pharmaceutical compositions containing said derivatives and the use of said derivatives in the treatment of disorders mediated by c-fms kinase. The present invention is further directed to a process for the preparation of said substituted pyridine derivatives.
    Type: Application
    Filed: March 13, 2014
    Publication date: January 21, 2016
    Inventors: Jie CHEN, Matthew DONAHUE, Heng-Keeng LIM, Ronghui LIN, Rhys SALTER, Jiejun WU
  • HAPTENS OF ARIPIPRAZOLE
    Publication number: 20140163206
    Abstract: The invention relates to compounds of Formula I, wherein R1, R2, and R3 are defined in the specification, useful for the synthesis of novel conjugates and immunogens derived from aripiprazole. The invention also relates to conjugates of an aripiprazole hapten and a protein.
    Type: Application
    Filed: August 20, 2013
    Publication date: June 12, 2014
    Applicants: Ortho-Clinical Diagnostics, Inc., JANSSEN PHARMACEUTICA NV
    Inventors: Ronghui LIN, Rhys SALTER, Thomas R. DeCORY, Eric HRYHORENKO, Bart REMMERIE, Banumathi SANKARAN
  • Antibodies to Aripiprazole Haptens and Use Thereof
    Publication number: 20140057299
    Abstract: Disclosed is an antibody which binds to aripiprazole, which can be used to detect aripiprazole in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of aripiprazole, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.
    Type: Application
    Filed: August 20, 2013
    Publication date: February 27, 2014
    Inventors: Eric Hryhorenko, Banumathi Sankaran, Thomas R. DeCory, Theresa Tubbs, Linda Colt, Bart M. Remmerie, Rhys Salter, Ronghui Lin
  • Antibodies to Aripiprazole and Use Thereof
    Publication number: 20140057300
    Abstract: Disclosed is an antibody which binds to aripiprazole, which can be used to detect aripiprazole in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of aripiprazole, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.
    Type: Application
    Filed: August 20, 2013
    Publication date: February 27, 2014
    Inventors: Eric Hryhorenko, Banumathi Sankaran, Thomas R. DeCory, Theresa Tubbs, Linda Colt, Bart M. Remmerie, Rhys Salter, Ronghui Lin
  • Bicyclic pyrimidine kinase inhibitors
    Patent number: 8314234
    Abstract: The present invention is directed to novel bicyclic pyrimidine compounds of Formula (I) or a form or composition thereof and the use thereof as inhibitors of ATP-protein kinase interactions.
    Type: Grant
    Filed: September 20, 2007
    Date of Patent: November 20, 2012
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Peter J. Connolly, Stuart Emanuel, Ronghui Lin, Yanhua Lu, Steven A. Middleton