Patents by Inventor Roy Johnson

Roy Johnson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5616307
    Abstract: Pollution from industrial plants which produce NO.sub.x and waste water is reduced by utilizing waste water to prepare aqueous NO.sub.x -reducing solutions. Total water hardness in the waste water is preferably maintained below 2500 ppm, silicate below 200 ppm and the calcium to magnesium ratio above 2:1. The aqueous NO.sub.x -reducing solution will preferably contain hardness suppressing compostions in effective amounts.
    Type: Grant
    Filed: March 11, 1996
    Date of Patent: April 1, 1997
    Assignee: Nalco Fuel Tech
    Inventors: Leonard Dubin, Vincent M. Albanese, Roy A. Johnson
  • Patent number: 5593980
    Abstract: This invention provides a new use of acids, esters, and salts of arylmethylphosphonates of Formula I, ##STR1## or a phosphonic acid of Formula II ##STR2## and derivatives as anti-inflammatory and anti-arthritic agents. Representative compounds include 4-dodecyloxybenzylphosphonic acid dimethyl ester, (2-naphthalenylmethyl)phosphonic acid dimethyl ester, and ([1,1'-biphenyl]-2-ylmethyl)phosphonic acid dimethyl ester.
    Type: Grant
    Filed: November 13, 1995
    Date of Patent: January 14, 1997
    Assignee: The Upjohn Company
    Inventor: Roy A. Johnson
  • Patent number: 5580640
    Abstract: A business form having an integrated label in its top ply or other sheets advantageously includes a release sheet which is only partially covered with a release coating in order to provide a controlled release. The controlled release is provided by skiving lines which preferably remove a portion of the release coating within a border on the release sheet. The adhesive layer is thereby directly connected to both the label and the release sheet. The release coating is penetrated intermittently by the skiving lines to remove a portion of the release coating. Alternatively, a pattern of release coating of silicone or the like may be printed in a pattern so that the release coating is only intermittently provided in covering relationship over the release sheet. The provision of intermittent direct contact between the adhesive and the release sheet provides improved adhesion of the label to the liner without detracting from the functionality of the form or the label.
    Type: Grant
    Filed: January 25, 1994
    Date of Patent: December 3, 1996
    Assignee: Ward/Kraft, Inc.
    Inventors: Roger E. Kraft, Merlin F. Mercer, Roy A. Johnson
  • Patent number: 5556878
    Abstract: This invention provides 7-deoxy-.DELTA..sup.6,7 -taxol and 7-deoxy-.DELTA..sup.6,7 -taxol analogs of Formula I: ##STR1## The compounds of Formula I are useful for the same cancers for which taxol has been shown active, including human ovarian cancer, breast cancer, and malignant melanoma as well as lung cancer, gastric cancer, colon cancer, head and neck cancer, and leukemia.
    Type: Grant
    Filed: June 10, 1994
    Date of Patent: September 17, 1996
    Assignee: The Upjohn Company
    Inventors: Robert C. Kelly, Roy A. Johnson, Harvey I. Skulnick, Eldon G. Nidy
  • Patent number: 5500417
    Abstract: This invention provides a new use of acids, esters, and salts of arylmethylphosphonates of Formula I, ##STR1## or phosphonic acid derivatives of Formula II ##STR2## as anti-inflammatory and anti-arthritic agents. Representative compounds include 4-dodecyloxybenzylphosphonic acid dimethyl ester, (2-naphthalenylmethyl)phosphonic acid dimethyl ester, and ([1,1 '-biphenyl]-2-ylmethyl)phosphonic acid dimethyl ester. The invention also provides novel acids, esters, and salts of arylmethylphosphonic acid, phosphonic acid and derivatives.
    Type: Grant
    Filed: March 16, 1995
    Date of Patent: March 19, 1996
    Assignee: The Upjohn Company
    Inventor: Roy A. Johnson
  • Patent number: 5405475
    Abstract: An apparatus and method for the continuous manufacture of printed, laminated stock is provided. The apparatus is designed to use plain, uncoated webs and at separate stations along a continuous path apply a release coating, apply an adhesive, join the webs together and imprint the combined webs to yield a final, laminated and imprinted stock. By die cutting and stripping the stock at further stations, discrete elements such as labels may be produced and carried by one of the webs. The apparatus preferably includes stations for curing and remoisturizing the release coated web, whereby a known moisture content is provided for the release coating prior to the application of adhesive and joining the webs into laminated stock. The process includes providing respective webs, applying a release coating to one web, joining the two webs together, imprinting at least one of the webs and routing the combined webs to a delivery station whereby the entire process is continuous and uninterrupted.
    Type: Grant
    Filed: May 28, 1993
    Date of Patent: April 11, 1995
    Assignee: Ward/Kraft
    Inventors: Roger E. Kraft, Merlin F. Mercer, Roy A. Johnson
  • Patent number: 5393264
    Abstract: A business form having a base sheet and a web adhered thereto forming a discrete pocket is provided. The web is applied and adhered to the base sheet whereby the surrounding margin of the web is recessed from the circumscribing edge of the base sheet. The continuous form can be fan-folded without binding or interference as the fold lines of the base sheet are free from interference by the web, The base sheet may be coated with carbonless transfer media as may be an insert ply positioned between the web and the base sheet to permit inscriptions on the base sheet to be transferred to a ply which may be subsequently removed.
    Type: Grant
    Filed: June 25, 1993
    Date of Patent: February 28, 1995
    Assignee: Ward/Kraft, Inc.
    Inventors: Roger E. Kraft, Merlin F. Mercer, Roy A. Johnson
  • Patent number: 5373095
    Abstract: Provided are cyclic hydrocarbons of Formula I ##STR1## with an aminoalkyl sidechain that are useful for treating phospholipase A2 mediated conditions, diabetes, and obesity.
    Type: Grant
    Filed: September 23, 1993
    Date of Patent: December 13, 1994
    Assignee: The Upjohn Company
    Inventors: Roy A. Johnson, Gordon L. Bundy, Gilbert A. Youngdale, Douglas R. Morton, Donald P. Wallach, deceased
  • Patent number: 5360797
    Abstract: Novel acids, esters, and salts of phenyl, naphthyl, quinoxalinyl, and biphenyl bisphosphonic acids and 1,2-oxaphosphepins are described. These compounds are useful as antiinflammatory and anti-arthritic agents. Also described are known compounds of the phenyl, naphthyl, quinoxalinyl, and biphenyl bisphosphonate classes which are also useful as antiinflammatory and anti-arthritic agents. Representative compounds include [1,2-phenyldiyl]bis(methylene)bisphosphonic acid tetramethyl ester, [2,3-quinoxalindiyl]bis(methylene)bisphosphonic acid tetramethyl ester, [[3-(propyl)-4-(methoxy)-1,8-naphthalenediyl]bis(methylene)]bisphosphonic acid tetramethyl ester, [2,6-naphthalenediylbis(methylene)bisphosphonic acid tetraethyl ester, and [2,2'-biphenylenebis(methyl)]bisphosphonic acid tetramethyl ester. Representative oxaphosphepins include the preferred 3,4-dihydro-3-methoxy-7-(phenylmethoxy)-1H-naphth[1,8de][1,2]oxaphosphepin -3-oxide.
    Type: Grant
    Filed: November 1, 1993
    Date of Patent: November 1, 1994
    Assignee: The Upjohn Company
    Inventors: Roy A. Johnson, Herman W. Smith
  • Patent number: 5347029
    Abstract: Provided are novel dialkyl (dialkoxyphosphinyl)methyl phosphates of formula ##STR1## which am useful as anti-inflammatory and anti-arthritic agents. The compounds are synthesized from the reaction of tetraethyl oxiranylidenebisphosphonate and unsubstituted or alkyl-amines. Representative compounds include 2-(benzylamino)-1-(diethoxyphosphinyl)ethyl phosphonic acid diethyl ester, 1-(diethoxyphosphinyl)-2-[2'-(1', 2', 3', 4'-tetrahydro)napthylamino]ethyl phosphonic acid diethyl ester, 2-(3-fluorobenzylamino)-1-(diethoxyphosphinyl)ethyl phosphonic acid diethyl ester, and 5,5 -dimethyl-2-[2-(3-fluorobenzyl)amino-1-[(5,5-dimethyl-1,3,2-dioxaphosphori nan-2-yl)oxy]ethyl]-1,3,2-dioxaphosphorinane P,2-dioxide.
    Type: Grant
    Filed: December 16, 1993
    Date of Patent: September 13, 1994
    Assignee: The Upjohn Company
    Inventor: Roy A. Johnson
  • Patent number: 5334712
    Abstract: Provided are cyclic hydrocarbons of Formula I ##STR1## with an aminoalkyl sidechain that are useful for treating phospholipase A2 mediated conditions, diabetes, and obesity.
    Type: Grant
    Filed: November 16, 1992
    Date of Patent: August 2, 1994
    Assignee: The Upjohn Company
    Inventors: Roy A. Johnson, Gordon L. Bundy, Gilbert A. Youngdale, Douglas R. Morton, Donald P. Wallach, deceased
  • Patent number: 5298498
    Abstract: Novel acids, esters, and salts of phenyl, naphthyl, quinoxalinyl, and biphenyl bisphosphonic acids and 1,2-oxaphosphepins are described. These compounds are useful as antiinflammatory and anti-arthritic agents. Also described are known compounds of the phenyl, naphthyl, quinoxalinyl, and biphenyl bisphosphonate classes which are also useful as antiinflammatory and anti-arthritic agents. Representative compounds include [1,2-phenyldiyl]bis (methylene)bisphosphonic acid tetramethyl ester, [2,3-quinoxalindiyl]bis(methylene)bisphosphonic acid tetramethyl ester, [[3-(propyl)-4-(methoxy)-1,8-naphthalenediyl]bis(methylene)]bisphosphonic acid tetramethyl ester, [2,6-naphthalenediylbis(methylene) bisphosphonic acid tetraethyl ester, and [2,2'-biphenylenebis(methyl)]bisphosphonic acid tetramethyl ester. Representative oxaphosphepins include the preferred 3,4-dihydro-3-methoxy -7-(phenylmethoxy)-1H-naphth[1,8de][1,2]oxaphosphepin-3-oxide.
    Type: Grant
    Filed: June 1, 1993
    Date of Patent: March 29, 1994
    Assignee: The Upjohn Company
    Inventors: Roy A. Johnson, Herman W. Smith
  • Patent number: 5298230
    Abstract: A process for the reduction of nitrogen oxides in the effluent of a gas turbine is presented. This process comprises forming an emulsion which comprises water and fuel oil and combusting the emulsion in the combustion can of a gas turbine to form an effluent; and contacting the effluent with a catalyst effective for the reduction of nitrogen oxides therein.
    Type: Grant
    Filed: May 1, 1992
    Date of Patent: March 29, 1994
    Assignee: Nalco Fuel Tech
    Inventors: Steven C. Argabright, Roy A. Johnson
  • Patent number: 5196542
    Abstract: Provided are cyclic hydrocarbons of Formula I ##STR1## with an aminoalkyl sidechain that are useful for treating phospholipase A2 mediated conditions, diabetes, and obesity.
    Type: Grant
    Filed: February 20, 1991
    Date of Patent: March 23, 1993
    Assignee: The Upjohn Company
    Inventors: Roy A. Johnson, Gordon L. Bundy, Gilbert A. Youngdale, Douglas R. Morton, Donald P. Wallach, deceased
  • Patent number: 5187299
    Abstract: Provided are cyclic hydrocarbons of Formula I ##STR1## with an aminoalkyl sidechain.
    Type: Grant
    Filed: November 13, 1991
    Date of Patent: February 16, 1993
    Assignee: The Upjohn Company
    Inventors: Roy A. Johnson, Gordon L. Bundy, Gilbert A. Youngdale, Douglas R. Morton, Donald P. Wallach, deceased, Wallach, Legal Representative, by Vera M.
  • Patent number: 5145874
    Abstract: Provided are cyclic hydrocarbons of Formula I ##STR1## with an aminoalkyl sidechain that are useful for treating phospholipase A2 mediated conditions, diabetes, and obesity.
    Type: Grant
    Filed: February 25, 1991
    Date of Patent: September 8, 1992
    Assignee: The Upjohn Company
    Inventors: Roy A. Johnson, Gordon L. Bundy, Gilbert A. Youngdale, Douglas R. Morton, Donald P. Wallach, deceased, by Vera M. Wallach, legal representative
  • Patent number: 5080427
    Abstract: A roll-formed door beam is provided for a vehicle which has an elongated shaped including a hat shaped portion and one to two looping portions. The hat shaped portion includes an upper flat surface for attachment and downwardly extending sides. The looping portions includes a bottom flat surface for attachment and looping sides which loopingly extend backwardly toward the base of the hat shaped portion. The looping sides cooperate with the side of the hat portion to stabilize the beam during flexure thus increasing the strength to thickness ratio of the beam.
    Type: Grant
    Filed: November 13, 1990
    Date of Patent: January 14, 1992
    Assignee: Shape Corporation
    Inventors: Peter Sturrus, Leslie A. Lewis, Roy Johnson
  • Patent number: 4917826
    Abstract: Provided are cyclic hydrocarbons of Formula I ##STR1## with an aminoalkyl sidechain that are useful for treating phospholipase A2 mediated conditions, diabetes, and obesity.
    Type: Grant
    Filed: June 16, 1987
    Date of Patent: April 17, 1990
    Assignee: The Upjohn Company
    Inventors: Roy A. Johnson, Gordon L. Bundy, Gilbert A. Youngdale, Douglas R. Morton, Donald P. Wallach, deceased
  • Patent number: 4882433
    Abstract: The present invention provides novel 3'-pyridinylalkenylindole-2-carboxylic acids and derivatives thereof of the formulas I and II ##STR1## which are useful as thromboxane A.sub.2 (TXA.sub.2) synthetase inhibitors and as such represent potent pharmacological agents.
    Type: Grant
    Filed: March 28, 1988
    Date of Patent: November 21, 1989
    Assignee: The Upjohn Company
    Inventors: Roy A. Johnson, Chiu-Hong Lin
  • Patent number: 4767865
    Abstract: The present invention provides novel 3'-pyridinylalkenylindole-2-carboxylic acids and derivatives thereof of the formula I and II ##STR1## which are useful as thromboxane A.sub.2 (TXA.sub.2) synthetase inhibitors and as such represent potent pharmacological agents.
    Type: Grant
    Filed: June 29, 1987
    Date of Patent: August 30, 1988
    Assignee: The Upjohn Company
    Inventors: Roy A. Johnson, Chiu-Hong Lin