Abstract: A frame system according to one embodiment includes a hollow outer frame element that includes a plurality of recesses formed along inner faces of walls of the outer frame element. The outer frame element further includes a plurality of ribs formed along the inner face and an inner landing that protrudes inwardly into a center opening of the outer frame element. The frame system also includes a back plate configured for insertion into the center opening. The back plate includes a plurality of locking ribs for reception within the plurality of recesses to generate a snap-fit attachment of the back plate to the hollow outer frame element.

Abstract: Embodiments of the present disclosure relate to sensors that can selectively bind to specific vicinal diols in the presence of other diols. These boronated vicinal diol-responsive sensor compounds can sense levels of specific vicinal diols and respond to these molecules in the body. In certain embodiments, the vicinal diol is a cis diol, for example, a hexose such as glucose. In certain embodiments the sensors are conjugated to a drug substance, and the sensors may change the biophysical characteristics, pharmacokinetics, and/or activity of the drug substance in response to the vicinal diol. The drug substance may be or include a polypeptide, such as an insulin, a human endocrine or incretin peptide, or an analogue thereof, and may contain one or more modified amino acids containing a vicinal diol-responsive sensor.

Abstract: In one embodiment, a frame assembly includes a mitered frame base including a plurality of rail sections that are joined together in corners of the mitered frame base by a plurality of fasteners. Each rail section includes a first surface for receiving a layered image arrangement. The frame assembly also includes a plurality of mitered splines that are configured to snap-fittingly mate with the plurality of rail sections. Each spline having a second surface that faces the first surface of one of the respective rail sections for securing the layered image arrangement between the spline and the rail section. A corner gap is formed between ends of respective mitered splines in each corner of the frame assembly. A plurality of corner pieces are received within the corner gaps to complete the frame assembly, the plurality of corner pieces snap-fittingly engaging the plurality of rails sections.

Abstract: A lawn sign attachment kit for attaching a sign to a sign frame. The kit includes a pair of adhesive connectors. Each adhesive connector includes a first end portion having a first width; a second end portion having a second width and an intermediate waist portion having a third width that is less than the first width and the second width. The adhesive connector has an inner face and an opposing outer face. The adhesive connector includes an integral finger that extends laterally outward from the second end portion. The adhesive connector having a first adhesive strip disposed transversely across the first end portion and a second adhesive strip disposed transversely across the second end portion and the integral finger.

Abstract: A tire-enhancement product has a container comprising a dissolvable packaging material; and a solute encased in the container that is inert to the solute. The container is configured to be placed in an interior volume of a tire, to which solvent can be added. The container is configured to dissolve when placed in a predetermined solvent, and the solute is configured to mix with the solvent to form a tire-enhancement mixture.

Abstract: A product for displaying an image or object (e.g., printed photo or a print, etc.) according to at least one implementation includes a first sheet having a front face and a rear face. An image or object is formed along the rear face. The product also includes an adhesive coated substrate, such as a ferrous metal substrate, to which the first sheet is adhesively affixed.

Abstract: A cube-shaped display article includes an inner cube-shaped base and a first image substrate that is formed of a plurality of individual image receiving sections that are arranged in a first pattern, such as a cross shape. The first image substrate having a plurality of crease lines to permit folding of the individual image receiving sections of the first image substrate for positioning the individual image sections against corresponding faces of the inner cube-shaped base. An outer hollow cube-shaped cage for placement over the inner cube-shaped base. The outer hollow cube-shaped cage captures the first image substrate which is located between the outer hollow cube-shaped cage and the inner cube-shaped base and serves to press the individual images against the corresponding faces of the inner cube-shaped base.

Abstract: A frame assembly includes a frame base and a rear panel including a plurality of side walls that are configured to be received within a plurality of side walls of the frame base. Along an external surface of each side wall of the rear panel there is at least one locking tab that is configured for reception within one corresponding locking opening of the frame base when the rear panel is inserted into the frame base so as couple the rear panel to the frame base in a snap-fitting manner and permit a canvas substrate to be captured therebetween for holding the canvas substrate across a front face of the frame base.

Abstract: A system for mounting a covering (e.g., a fabric material) upon a frame is constructed from a plurality of elongated frame parts. Each frame part has two mitered ends and a channel formed therein. The related mounting method includes the steps of: (a) using a jig to hold the fabric material against the frame; (b) inserting a plurality of retaining splines within respective channels so as to capture the fabric material within the channels between one retaining spline and a corresponding floor of the channel, whereby a plurality of corner pleats are formed; and (c) using a tool to invert each corner pleat into a corner joint formed between respective adjacent frame parts so as to form an internal fold at each corner of the frame.

Abstract: A frame system according to one embodiment includes a mount body having an inner surface and an opposing outer surface. The outer surface has an adhesive body applied thereto. The adhesive body has an adhesive on an outer surface thereof for contacting and bonding with a support surface. The frame system further includes an outer frame element having a first opening through which an image substrate is visible. The outer frame element has a first surface against which the image substrate seats. A back plate is configured for attachment to the outer frame element and the back plate includes a second opening that receives the adhesive body. The back plate further includes a forward protrusion against which the image substrate seat. A mount space is defined between the outer frame element and the back plate in which the mount body is disposed and is configured to move in at least two directions for adjusting a position of the frame system on the support surface. At least one biasing element (e.g.

Abstract: Methods and systems for image analysis are provided, and in particular for identifying a set of base-calling locations in a flow cell for DNA sequencing. These include capturing flow cell images after each sequencing step performed on the flow cell, and identifying candidate cluster centers in at least one of the flow cell images. Intensities are determined for each candidate cluster center in a set of flow cell images. Purities are determined for each candidate cluster center based on the intensities. Each candidate cluster center with a purity greater than the purity of the surrounding candidate cluster centers within a distance threshold is added to a template set of base-calling locations.

Abstract: A frame system according to one embodiment includes a hollow outer frame element that includes a plurality of recesses formed along inner faces of walls of the outer frame element. The outer frame element further includes a plurality of ribs formed along the inner face and an inner landing that protrudes inwardly into a center opening of the outer frame element. The frame system also includes a back plate configured for insertion into the center opening. The back plate includes a plurality of locking ribs for reception within the plurality of recesses to generate a snap-fit attachment of the back plate to the hollow outer frame element.

Abstract: A tire-enhancement product has a container comprising a dissolvable packaging material; and a solute encased in the container that is inert to the solute. The container is configured to be placed in an interior volume of a tire, to which solvent can be added. The container is configured to dissolve when placed in a predetermined solvent, and the solute is configured to mix with the solvent to form a tire-enhancement mixture.

Abstract: A vertical slot hanger assembly includes a substrate having a top edge and a bottom edge and a plurality of holes or slits formed therein along each of the top edge and the bottom edge. The assembly further includes a top rail and a bottom rail. Each of the top rail and the bottom rail includes a recessed channel that extends in a longitudinal direction. Each rail has a plurality of blind holes formed therein. Each blind hole intersects the recessed channel. The top edge of the substrate is received within the recessed channel of the top rail and the bottom edge of the substrate is received within the recessed channel of the bottom rail. The system further includes an elongated hanging element that is disposed within the recessed channel between the top edge of the substrate and a top surface of the recessed channel. The system includes a plurality of fasteners for reception in the plurality of blind holes.

Abstract: A method for assembling a canvas print includes the steps of: preparing a canvas substrate that includes a printed side; placing the canvas substrate with the printed side facing down; disposing a base frame over the canvas substrate; folding edges of the canvas substrate over sides of the base frame; inserting a rear panel into the base frame; and pressing the rear panel downward until a snap-fit connection is realized between the rear panel and the base frame with the folded edges of the canvas substrate being captured between the rear panel and the base frame and being taught across a forward face of the base frame.

Abstract: An article for hanging on a support surface includes a substrate having a first end and a second end. The article includes a pair of rails with each rail including a recessed channel that extends in a longitudinal direction. A pair of splines is provided with each spline including a raised ridge that extends in a longitudinal direction. The raised ridge is configured for insertion into the recessed channel. The article also includes a first pair of end caps. Each end cap of the first pair of end caps having an end walls and side walls that define a hollow interior, wherein each end cap of the first pair of end caps further includes slots that are formed in two of the side walls that are opposite one another. The article includes an elongated hanging element that has enlarged portions at two opposite ends thereof. The elongated hanging element passes through the slots of the first pair of end caps with the enlarged portions being located external to the first pair of end caps.

Abstract: Methods and systems for image analysis are provided, and in particular for identifying a set of base-calling locations in a flow cell for DNA sequencing. These include capturing flow cell images after each sequencing step performed on the flow cell, and identifying candidate cluster centers in at least one of the flow cell images. Intensities are determined for each candidate cluster center in a set of flow cell images. Purities are determined for each candidate cluster center based on the intensities. Each candidate cluster center with a purity greater than the purity of the surrounding candidate cluster centers within a distance threshold is added to a template set of base-calling locations.

Abstract: A frame system according to one embodiment includes a mount body having an inner surface and an opposing outer surface. The outer surface has an adhesive body applied thereto. The adhesive body has an adhesive on an outer surface thereof for contacting and bonding with a support surface. The frame system further includes an outer frame element having a first opening through which an image substrate is visible. The outer frame element has a first surface against which the image substrate seats. A back plate is configured for attachment to the outer frame element and the back plate includes a second opening that receives the adhesive body. The back plate further includes a forward protrusion against which the image substrate seat. A mount space is defined between the outer frame element and the back plate in which the mount body is disposed and is configured to move in at least two directions for adjusting a position of the frame system on the support surface. At least one biasing element (e.g.

Abstract: A frame system includes a mount having an outer surface for receiving an adhesive for placement on a support surface and an inner surface that includes a plurality of first coupling elements. The frame system also includes a hollow outer frame element and a back plate configured for insertion into and attachment to the outer frame element. The back plate includes a plurality of second coupling elements that mate with the first coupling elements for attaching the back plate to the mount in such a way that the back plate can rotate relative to the mount to allow for adjustment of the combined outer frame element and the back plate.

Abstract: Methods and systems for image analysis are provided, and in particular for identifying a set of base-calling locations in a flow cell for DNA sequencing. These include capturing flow cell images after each sequencing step performed on the flow cell, and identifying candidate cluster centers in at least one of the flow cell images. Intensities are determined for each candidate cluster center in a set of flow cell images. Purities are determined for each candidate cluster center based on the intensities. Each candidate cluster center with a purity greater than the purity of the surrounding candidate cluster centers within a distance threshold is added to a template set of base-calling locations.