Abstract: Systems and methods for initiating an action based on electronic activities of a user. Generally, a computing device receives a policy for enabling cryptographically secure tracking of electronic activities of a user and a particular electronic computing device. The policy can include definitions for a multiple actions to be taken with respect to certain electronic activities resulting from interaction by the user with the at least one computing device. The computing device can identify a particular electronic activity resulting from user interaction with the at least one computing device. The computing device can determine a particular action to take by applying the policy to the particular electronic activity. The computing device can initiate the particular action with respect to the particular electronic activity.

Abstract: Compounds that inhibit KRas G12D. In particular, compounds that inhibit the activity of KRas G12D, pharmaceutical compositions comprising the compounds and methods of use therefor, and in particular, methods of treating cancer. The compounds have a general structure represented by Formula (I): or a pharmaceutically acceptable salt thereof.

Abstract: In one or more arrangements, a sweep system for livestock grazing is provided to facilitate movement of livestock when an enclosure is moved. The system includes a frame having a front end, a rear end, and opposing sides. The system has one or more wheel assemblies attached to the frame to facilitate movement of the frame along the ground. The system includes a sweep mechanism connected to the frame that facilitates movement of the livestock.

Abstract: According to one aspect, a fastening device may include a coupling body having (1) a portion configured to couple to a distal end of a medical device, (2) a cartridge holder, and (3) an anvil pivotably coupled to the cartridge holder. The cartridge holder and the anvil may extend distally from the portion and may be configured to extend distally of a distalmost face of the medical device when the portion is coupled to the distal end of the medical device. A flexible member may be configured to extend through a channel of the medical device. A fastener cartridge may be coupled to a distal end of the flexible member, including at least one fastener, and may be configured for releasable coupling to the cartridge holder.

Abstract: A military vehicle includes an engine, an energy storage system, an accessory drive coupled to the engine and including an air compressor and a first motor, a second motor coupled to an axle, and a clutch positioned between the engine and the second motor. The clutch is spring-biased into engagement with the engine and pneumatically disengaged by an air supply selectively provided thereto based on operation of the air compressor. In an engine mode, (i) the clutch does not receive the air supply such that the engine is coupled to the second motor and (ii) the engine drives (a) the accessory drive and (b) the axle through the second motor. In the electric mode, (i) the first motor drives the air compressor to compress air to facilitate supplying the air supply to the clutch to disengage the clutch and decouple the engine from the second motor and (ii) the second motor drives the axle.

Abstract: The present invention provides multispecific antigen-binding molecules that bind both a T-cell antigen (e.g., CD3) and a target antigen (e.g., a tumor associated antigen, a viral or bacterial antigen), and which include a single polypeptide chain that is multivalent (e.g., bivalent) with respect to T-cell antigen binding, and uses thereof.

Abstract: This disclosure relates to pole bases, specifically to light pole base cabinets that can house items. The pole base cabinets can be positioned between a light pole and a footing. The pole base cabinets provide a base to a light pole while adding additional functionality. The cabinets can include a main opening allowing access to a cavity in which items can be stored. Access to the cavity can be restricted with a door that uncovers and covers the main opening. The pole base cabinets can include support panels, internal stiffening panels, external stiffening panels, support tabs, flanges, tabs, a peripheral wall, and other features to provide structural support and enclose the contents in the pole base cabinet.

Abstract: Medical devices and methods of using medical devices are disclosed. An example tissue retraction device includes a first engagement member having a first end and a second end, a second engagement member having a first end and a second end, a first elastic member attached to the second end of the first engagement member, and a first alignment member having a first end, a second end and a lumen extending therethrough. Further, the tissue retraction device has a first length, the first alignment member has a second length, the first elastic member extends within the lumen of the first alignment member and the second length of the first alignment member is less than or equal to the first length of the tissue retraction device.

Abstract: The present disclosure provides a systems, methods, and computer-readable media for distributed cybersecurity data collection and traffic masking. According to some aspects, a system includes a server and multiple logical groups of node devices associated with respective characteristics. The characteristics may be related to different geographical or geopolitical locations, different scheduled operations, or the like. A first node device of a first logical group may execute a data collection agent based on first parameter values corresponding to characteristics of the logical first group to communicate first masked traffic to a network target to obtain first cybersecurity data. A second node device of a second logical group may execute the data collection agent based on second parameter values corresponding to characteristics of the second logical group to communicate second masked traffic to the network target to obtain second cybersecurity data.

Abstract: Techniques for enabling access in a multi-assistant speech processing system are described, where a first assistant system may use components of a second assistant system as data processing components. Runtime operational data and user input data related to the first assistant may be kept separate from the processing data and input data related to the second assistant by propagating a first account ID, for user inputs directed to the first assistant, through the processing pipeline, and using a second account for user inputs directed to the second assistant. A mapping between the first account ID and the second account ID may be accessible to a select number of system components. Handoffs between the two assistants are handled in a manner where data related to one assistant is not accessible by the other assistant.

Abstract: Devices, systems, and methods for coupling tubing to a fluid reservoir to provide liquid to an endoscope system. A manifold for coupling to a fluid reservoir and a tubing assembly may include first portion interfacing with an interior of the fluid reservoir and a second portion configured to interface with tubing to be fluidly coupled to the interior of the reservoir. The first portion may include one or more openings to allow gas to pass into the fluid reservoir and liquid to pass out of the fluid reservoir. The second portion may include one or more ports for connecting to tubing that brings gas to the fluid reservoir and receives liquid from the fluid reservoir. The manifold may include a valve that selectively allows gas to pass into the fluid reservoir.

Abstract: A coupling system is described that allows users to avoid having to manipulate two tools at the same time while reaching around to both sides of the coupled components. A lock plate can rest above one or more holes passing through (and for joining together) the components. A blade pin with a partially hollow cylinder can be inserted through holes in the lock plate and at least partially through the holes. A blade bolt can be inserted into the holes and the cylinder from the other side. The blade bolt can comprise an o-ring that engages with an inner diameter of a portion of the cylinder and holds the parts together with an interference fit. A portion of the bolt can extend through the top of the holes, and a washer and nut can be attached to or about a threaded portion of the bolt. During each state of installation a user will not have to reach to both sides of the system while manipulating multiple tools.

Abstract: Surgical instruments for interfacing with implants can include an inserter configured to dock to a unilateral portion of an implant. The inserter can include a control shaft that is configured to lock or unlock the inserter coupling with the implant. Actuation of the control shaft can occur by way of a knob that can control movement of the control shaft. The inserter can facilitate positioning of the implant relative to a surgical site and allow for application of counter-torque when imparting torque for tightening a set screw, etc. Additional instruments can also be used to manipulate the implant. For example, auxiliary instruments can be coupled to the inserter, such as a reducer instrument, to facilitate rod reduction, etc. Alternatively or in addition, a holder instrument can be used that has a threaded distal engagement feature for coupling to the implant to facilitate positioning thereof.

Abstract: Modular connectors and methods are disclosed that provide two sides of a connector in modular and interchangeable fashion. The modular design can be enhanced to add various useful features to one or both sides of the connectors, including the use of rods, hooks, rod receivers of various configurations, etc. This modular approach can allow the assembly of various unique connectors from a pool of components that are interchangeable while minimizing manufacturing cost and complexity.

Abstract: A vehicle includes a support structure. The vehicle also includes a side door operable to move relative to the support structure between an open position and a closed position. In the open position of the side door, access to a vehicle interior of the vehicle is provided. In the closed position of the side door, the side door extends across a longitudinal centerline of the vehicle. The vehicle further includes a plurality of pivot members, each pivotably coupled to the support structure at a first end and pivotably coupled to the side door at a second end. The side door is movable between the open and closed positions via pivotal movement of each of the plurality of pivot members relative to the support structure and pivotal movement of the side door relative to each of the plurality of pivot members.

Abstract: An anti-cant indicator assembly, components thereof, and associated methods. The anti-cant indicator assembly indicates the orientation of a weapon with respect to vertical. The anti-cant indicator assembly includes a mount configured to mount to the weapon, a level including a vial containing a bubble and a pivot connection connecting the level to the mount. The pivot connection is configured to permit movement of the level with respect to the mount about the pivot connection between an operational position in which the bubble can be referenced by the user for indicating orientation of the weapon with respect to vertical, and a stowed position different from the operational position. The pivot connection can include a retainer configured to releasably retain the level in at least one of the operational position or the stowed position. The level can be selectively movable with respect to the mount to calibrate the anti-cant indicator.

Abstract: A data storage system may connect a non-volatile memory to a quarantine module that generates a quarantine strategy in response to a pending data access request to the non-volatile memory. The quarantine strategy can proactively prescribing a plurality of status levels for physical data addresses of the non-volatile memory. A comparison of a volume of errors for the non-volatile memory to a first threshold of the quarantine strategy with the quarantine module may prompt the alteration of a first status level of the plurality of status levels for a first physical data address of the non-volatile memory, as directed by the quarantine strategy.

Abstract: Methods and systems for coupling gas and water supply tubes to a container. An illustrative container and tube set may comprise a container configured to contain a fluid, the container having a bottom portion and a top portion, a water supply tube including a first end, a second end, and a first lumen, a gas supply tube including a first end, a second end, and a second lumen, and a weight coupled to the first end of the water supply tube and a first end of the gas supply tube. The first lumen may be in selective fluid communication with the bottom portion of the container and the second end of the water supply tube positioned external to the container. The second lumen may be in operative fluid communication with the container and the second end of the gas supply tube is positioned external to the container.

Abstract: One variation of a system for power distribution of a trailer includes: a trailer chassis; a driven axle suspended from the trailer chassis; and a motor coupled to the driven axle. The system further includes a battery assembly coupled to the trailer chassis and configured to supply electrical energy to the motor to drive the driven axle and source electrical energy from the motor to slow motion of the driven axle. The system also includes a charging panel coupled to the trailer chassis and configured to couple to an external charging element. The system further includes a panel actuator configured to advance the charging panel from the trailer chassis to an open position to form a target gap between the external charging element and the charging panel and to retract the charging panel to a closed position to decouple the charging panel from the external charging element.