Abstract: The disclosure relates to medical tubes and methods of manufacturing medical tubes. The tube may be a composite structure made of two or more distinct components that are spirally wound to form an elongate tube. For example, one of the components may be a spirally wound elongate hollow body, and the other component may be an elongate structural component also spirally wound between turns of the spirally wound hollow body The tube need not be made from distinct components, however. For instance, an elongate hollow body formed (e.g., extruded) from a single material may be spirally wound to form an elongate tube. The elongate hollow body itself may in transverse cross-section have a thin wall portion and a relatively thicker or more rigid reinforcement portion. The tubes can be incorporated into a variety of medical circuits or may be employed for other medical uses.

Abstract: A system for interconnecting enhanced and diversified communications with commercial applications using efficient and user-friendly features and methods by which users can create, share, and proliferate symbols, use translations, message contractions, message expansions, hidden messages, scrolling or bill-boarding messages, timed messages, Morse messages, and inter-language translations, all using various forms of formatting and presentation configurations.

Abstract: Various embodiments provide methods and systems for the biphasic iontophoretic transdermal delivery of therapeutic agents. An embodiment of a method for such delivery comprises positioning at least one electrode assembly in electrical communication with a patient's skin. The assembly includes a solution comprising a therapeutic agent which passively diffuses into the skin. A dose of agent is delivered from the assembly into the skin during a first period using a first current having a characteristic e.g., polarity and magnitude, to repel the agent out of the assembly. During a second period, a second current having a characteristic to attract the agent is used to retain the agent in the assembly such that delivery of agent into skin is minimized. A dose of agent may be delivered on demand by an input from the patient. Embodiments may be used for delivery of agents which cause adverse effects from unwanted passive diffusion.

Abstract: A computer readable storage medium includes executable instructions to define a processor with guest mode control registers supporting guest mode operating behavior defined by guest context specified in the guest mode control registers. The guest mode control registers include a control bit to specify a guest access blocked register state and a shared register state. Root mode control registers support root mode operating behavior defined by root context specified in the root mode control registers. The root mode control registers include control bits to enable replicated register state access and shared register state access. The guest context and the root context support virtualization of hardware resources such that multiple operating systems supporting multiple applications are executed by the hardware resources.

Abstract: Disclosed herein are methods and systems for presenting personas according to a common cross-client configuration. An embodiment takes the form of a method that includes extracting a persona from video frames being received from a video camera. The method also includes transmitting an outbound stream of persona data that includes the extracted persona. The method also includes receiving at least one inbound stream of persona data, where the at least one inbound stream of persona data includes one or more other personas. The method also includes presenting a full persona set of the extracted persona and the one or more other personas on a user interface according to a common cross-client persona configuration. The method also includes presenting one or more shared-content channels on the user interface according to a common cross-client shared-content-channel configuration.

Abstract: Embodiments disclose systems and methods for transmitting user-extracted video and content more efficiently by recognizing that user-extracted video provides the potential to treat parts of a single frame of a user-extracted video differently. An alpha mask of the image part of the user-extracted video is used when encoding the image part so that it retains a higher quality upon transmission than the remainder of the user-extracted video.

Abstract: Disclosed herein are systems and methods for iterative adjustment of video-capture settings based on identified persona. In an embodiment, a method includes receiving video frames being captured by a video camera of an ongoing scene. The method also includes identifying a persona in one or more of the received frames at least in part by identifying, in each such frame, a set of pixels that is representative of the persona in the frame and that does not include any pixels representative of a background of the frame. The method also includes selecting, based collectively on the brightness values of the pixels in the identified set of pixels of one or more frames, an adjustment command for one or more adjustable video-capture settings of the camera, as well as outputting the selected commands to the camera for use in continuing to capture video data representative of the ongoing scene.

Abstract: Embodiments disclose extracting a user persona from a video of arbitrary duration and associating that persona with text for a chat session. Embodiments cause the persona to be extracted at the moment text is sent or received to convey the body language associated with the text.

Abstract: A system and method is disclosed for extracting a user persona from a video and embedding that persona into a background feed that may have other content, such as text, graphics, or additional video content. The extracted video and background feed are combined to create a composite video that comprises the display in a videoconference. Embodiments cause the user persona to be embedded at preset positions, or in preset formats, or both, depending on the configuration, position, or motion of the user's body.

Abstract: A system for interconnecting enhanced and diversified communications with commercial applications using efficient and user-friendly features and methods by which users can create, share, and proliferate symbols, use translations, message contractions, message expansions, hidden messages, scrolling or bill-boarding messages, timed messages, Morse messages, and inter-language translations, all using various forms of formatting and presentation configurations.

Abstract: Embodiments provide devices, systems and methods for the transdermal delivery of chelated compounds. One embodiment provides a method for the iontophoretic transdermal delivery of a chelated iron complex for the treatment of anemia. A first patch comprising an active electrode and a chelated iron complex is applied to the skin; a second patch containing an electrode is also applied. An electrical current is then delivered to the skin from the active electrode. The chelated complex is transported across the skin via electromotive force from the current, with the iron being substantially chromogenically unreactive with the skin during transport so that there is little or no tattooing of the skin due to the formation of insoluble oxidative products. The complex is then dissociated by phagocytosis or related process to release the iron where it may be bound by transferrin or ferritin and carried to other sites for storage or metabolic use.

Abstract: A system and method is disclosed for extracting a user persona from a video and embedding that persona into a background feed that may have other content, such as text, graphics, or additional video content. The extracted video and background feed are combined to create a composite video that comprises the display in a videoconference. Embodiments cause the user persona to be embedded at preset positions, or in preset formats, or both, depending on the configuration, position, or motion of the user's body.

Abstract: Improved branch target buffers (BTBs) and methods of processing data in a microprocessor with a pipeline are provided. According to various embodiments, a BTB is provided that includes a non-return buffer, a return buffer, and a multiplexer. The non-return buffer is designed to store a multiple of non-return entries. Each non-return entry corresponds to a non-return type instruction. The return buffer is designed to store a plurality of return entries that each correspond to a return type instruction. Additionally, the return buffer may generate a control signal. The multiplexer also generates a control signal and outputs either data from the non-return buffer or data from a return prediction stack (RPS). Whether the multiplexer returns data from the non-return buffer or the RPS depends on the control signal.

Abstract: Embodiments provide devices, systems and methods for the transdermal delivery of chelated compounds. One embodiment provides a method for the iontophoretic transdermal delivery of a chelated iron complex for the treatment of anemia. A first patch comprising an active electrode and a chelated iron complex is applied to the skin; a second patch containing an electrode is also applied. An electrical current is then delivered to the skin from the active electrode. The chelated complex is transported across the skin via electromotive force from the current, with the iron being substantially chromogenically unreactive with the skin during transport so that there is little or no tattooing of the skin due to the formation of insoluble oxidative products. The complex is then dissociated by phagocytosis or related process to release the iron where it may be bound by transferrin or ferritin and carried to other sites for storage or metabolic use.

Abstract: A system and method for profiling runtime system events of a computer system may include associating a data source type with detected system events. The system events may be detected dependent on information included in a reply message received by a processor in response to a data request or other transaction request message. The reply message may include information characterizing a source type of a source of data included in the reply message. The source type information may indicate that the source is remote or local; that it is a shared or a private storage location; that the data is supplied via a cache-to-cache transfer; or that the data is sourced from a coherency domain other than that of the requesting process. Instructions, events, messages, and replies may be sampled, and extended address information corresponding to the samples may be stored in an event set database for performance analysis.

Abstract: A method includes assigning unique guest identifications to different guests, specifying an address region and permissions for the different guests and controlling a guest jump from one physical memory segment to a second physical memory segment through operational permissions defined in a root memory management unit that supports guest isolation and protection.

Abstract: A processor may include several processor cores, each including a respective higher-level cache, wherein each higher-level cache includes higher-level cache lines; and a lower-level cache including lower-level cache lines, where each of the lower-level cache lines may be configured to store data that corresponds to multiple higher-level cache lines. In response to invalidating a given lower-level cache line, the lower-level cache may be configured to convey a sequence including several invalidation packets to the processor cores via an interface, where each member of the sequence of invalidation packets corresponds to a respective higher-level cache line to be invalidated, and where the interface is narrower than an interface capable of concurrently conveying all invalidation information corresponding to the given lower-level cache line. Each invalidation packet may include invalidation information indicative of a location of the respective higher-level cache line within different ones of the processor cores.

Abstract: Embodiments of the invention provide compositions comprising bio degradable polymers, medical implants fabricated from these compositions and methods of using such implants. Many embodiments provide medical implants comprising a first polymer backbone having a first rate of biodegradation and a second polymer backbone having a second rate of biodegradation faster than the first rate. In some embodiments, the second backbone is configured to be replaced by a natural tissue layer. The first backbone provides a scaffold for the implant while the second backbone degrades. This scaffold can enhance mechanical properties of the implant including various aspects of mechanical strength such as tensile, bending, hoop and yield strength; and elasticity. The scaffold also serves to maintain a minimum level of structural support of the implant during the period of degradation of the second backbone or for the entire life of the implant so that the implant does not mechanically fail.

Abstract: A computer readable storage medium includes executable instructions to define a processor with guest mode control registers supporting guest mode operating behavior defined by guest context specified in the guest mode control registers. The guest mode control registers include a control bit to specify a guest access blocked register state and a shared register state. Root mode control registers support root mode operating behavior defined by root context specified in the root mode control registers. The root mode control registers include control bits to enable replicated register state access and shared register state access. The guest context and the root context support virtualization of hardware resources such that multiple operating systems supporting multiple applications are executed by the hardware resources.

Abstract: This invention describes novel pyrazole compounds of formula IV: wherein Ring D is a 5-7 membered monocyclic ring or 8-10 membered bicyclic ring selected from aryl, heteroaryl, heterocyclyl or carbocyclyl; Rx and Ry are independently selected from T-R3, or taken together with their intervening atoms to form a fused, unsaturated or partially unsaturated, 5-8 membered ring having 1-3 ring heteroatoms selected from oxygen, sulfur, or nitrogen; and R2, R2?, T, and R3 are as described in the specification. The compounds are useful as protein kinase inhibitors, especially as inhibitors of aurora-2 and GSK-3, for treating diseases such as cancer, diabetes and Alzheimer's disease.