Patents by Inventor Scott Jeffrey

Scott Jeffrey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Capsule machine and components
    Patent number: 9700171
    Abstract: A machine is provided for preparing a desired product from a capsule containing desired ingredients. The machine includes a brew chamber that is adapted to hold the capsule at a downward angle relative to a horizontal plane. A cover for the brew chamber is adapted to move between an open position and a closed position. A loading mechanism is provided for extending and retracting the brew chamber. An injection system is provided for injecting a fluid into the capsule. A fluid transfer system is provided for transferring a desired fluid from a fluid source to the injection system. A dispensing system is provided for dispensing product to a receptacle. A reusable capsule is also provided for use with the machine.
    Type: Grant
    Filed: April 3, 2014
    Date of Patent: July 11, 2017
    Assignee: 2266170 Ontario Inc.
    Inventors: Scott Jeffrey Hanneson, Thomas Joseph Pfeifer
  • BETA-GLUCURONIDE-LINKER DRUG CONJUGATES
    Publication number: 20170189540
    Abstract: Ligand Drug conjugate compounds comprising a ?-glucuronide-based linker and methods of using such compounds are provided.
    Type: Application
    Filed: September 25, 2013
    Publication date: July 6, 2017
    Applicant: Seattle Genetics, Inc.
    Inventor: Scott Jeffrey
  • BETA-GLUCURONIDE-LINKER DRUG CONJUGATES
    Publication number: 20170189542
    Abstract: Ligand Drug conjugate compounds comprising a ?-glucuronide-based linker and methods of using such compounds are provided.
    Type: Application
    Filed: March 20, 2017
    Publication date: July 6, 2017
    Applicant: SEATTLE GENETICS, INC.
    Inventor: Scott Jeffrey
  • Power distribution systems and methods of testing a power distribution system
    Patent number: 9692223
    Abstract: Power distribution systems and methods are described. In one example, a method of testing a power distribution zone select interlocking system including a first circuit protection device and a second circuit protection device coupled to the first circuit protection device downstream of the first circuit protection device is described. The method includes receiving, by the second circuit protection device, an input instructing the second circuit protection device to test communication between the first circuit protection device and the second circuit protection device, and outputting, by the second circuit protection device, a blocking signal in response to the input. The first circuit protection display an indication of reception of the blocking signal to confirm proper interconnection of the zone select interlocking signals.
    Type: Grant
    Filed: October 31, 2013
    Date of Patent: June 27, 2017
    Assignee: General Electric Company
    Inventors: Arun Kumar Singh, Gary Vincent Hanrahan, Scott Jeffrey Hall
  • TARGETED PYRROLOBENZODIAZAPINE CONJUGATES
    Publication number: 20170143846
    Abstract: Provided are Conjugate comprising PBDs conjugated to a targeting agent and methods of using such PBDs.
    Type: Application
    Filed: February 1, 2017
    Publication date: May 25, 2017
    Inventors: Philip Wilson HOWARD, Scott JEFFREY, Patrick BURKE, Peter SENTER
  • Sensor based measurement and purge control of fuel vapors in internal combustion engines
    Patent number: 9631567
    Abstract: A fuel control system for a vehicle includes a pressure compensation module that compensates an intake oxygen signal based on an intake pressure signal and that generates a compensated intake oxygen signal. A blow-by estimation module generates an estimated blow-by flow. A purge flow estimation module estimates the purge flow based on the compensated intake oxygen signal and the estimated blow-by flow. A fuel control estimation module reduces fueling to injectors of an engine of the vehicle based on the purge flow.
    Type: Grant
    Filed: August 15, 2013
    Date of Patent: April 25, 2017
    Assignee: GM Global Technology Operations LLC
    Inventors: B. Jerry Song, Martino Casetti, Scott Jeffrey, Louis A. Avallone
  • Targeted pyrrolobenzodiazapine conjugates
    Patent number: 9592240
    Abstract: Provided are Conjugate comprising PBDs conjugated to a targeting agent and methods of using such PBDs.
    Type: Grant
    Filed: January 14, 2016
    Date of Patent: March 14, 2017
    Assignees: SEATTLE GENETICS INC., MEDIMMUNE LIMITED
    Inventors: Philip Wilson Howard, Scott Jeffrey, Patrick Burke, Peter Senter
  • CD33 antibodies and use of same to treat cancer
    Patent number: 9587019
    Abstract: The invention provides murine, chimeric, and humanized antibodies that specifically bind to CD33. The antibodies are useful for treatment and diagnoses of various cancers as well as detecting CD33.
    Type: Grant
    Filed: May 15, 2013
    Date of Patent: March 7, 2017
    Assignee: SEATTLE GENETICS, INC.
    Inventors: May Kung Sutherland, Maureen Ryan, Django Sussman, Patrick Burke, Scott Jeffrey
  • Fiber reinforced helmet
    Patent number: 9585433
    Abstract: A helmet with an outer shell made from a fiber reinforced material, and preferably a fiber reinforced polymer. The helmet preferably has a critical impact area that contains a greater concentration of fibers. Preferably, the helmet has a weight, offset, and dimensions which are comparable to a helmet with an outer shell that is not made from a fiber reinforced material. The helmet is preferably stiffer and more protective than a conventional helmet not having a fiber reinforced outer shell.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: March 7, 2017
    Assignee: Rawlings Sporting Goods Company, Inc.
    Inventors: Douglas Wade Heimer, Matthew V. Vacek, Biju Mathew, Scott Jeffrey Sorensen
  • Methods of manufacturing large-area sputtering targets using interlocking joints
    Patent number: 9564299
    Abstract: In various embodiments, joined sputtering targets are formed at least in part by spray deposition of the sputtering material and/or welding.
    Type: Grant
    Filed: February 12, 2016
    Date of Patent: February 7, 2017
    Assignee: H.C. Starck, Inc.
    Inventors: Scott Jeffrey Volchko, William Loewenthal, Stefan Zimmermann, Mark Gaydos, Steven Alfred Miller
  • NMR Sensor For Analyzing Core or Fluid Samples From A Subsurface Formation
    Publication number: 20170030845
    Abstract: A sensor and a method are disclosed for analyzing fluid and/or rock samples from a subsurface formation. Embodiments of the sensor and method utilize an array of magnets arranged in a specific way. The array and its arrangement may allow for NMR analysis of multiple samples or analysis of fluid samples which were not possible with existing technology. Further details and advantages of various embodiments of the method are described in more detail herein.
    Type: Application
    Filed: July 29, 2015
    Publication date: February 2, 2017
    Inventors: Scott Jeffrey Seltzer, Haijing Wang, Boqin Sun
  • Fuel Control Systems And Methods For Preventing Over Fueling
    Publication number: 20170002755
    Abstract: A fuel control system for an engine includes a closing module and a purge control module. The closing module commands closing of a purge valve in response an engine speed transitioning from greater than a predetermined speed to less than the predetermined speed while the purge valve is in an open state. The predetermined speed is less than a predetermined target speed of the engine and is greater than zero. The purge control module transitions the purge valve from the open state to a closed state in response to the command.
    Type: Application
    Filed: August 31, 2015
    Publication date: January 5, 2017
    Inventors: Steven Ward MAJORS, Scott JEFFREY, Jason WEST
  • Pyrrolobenzodiazepines and targeted conjugates
    Patent number: 9526798
    Abstract: A compound, or a pharmaceutically acceptable salt or solvate thereof, or conjugates thereof, selected from the group consisting of formula wherein: (a) R10 is H, and R11 is OH, ORA, where RA is saturated C1-4 alkyl; (b) R10 and R11 form a nitrogen-carbon double bond between the nitrogen and carbon atoms to which they are bound; or (c) R10 is H and R11 is S02M, where z is 2 or 3 and M is a monovalent pharmaceutically acceptable cation, or both M together are a divalent pharmaceutically acceptable cation.
    Type: Grant
    Filed: October 12, 2012
    Date of Patent: December 27, 2016
    Assignees: SEATTLE GENETICS, INC., MEDIMMUNE LIMITED
    Inventors: Scott Jeffrey, Patrick Burke, Philip Wilson Howard
  • Methods of using monomethylvaline compositions having phenylalanine carboxy modifications at the C-terminus
    Patent number: 9522194
    Abstract: Auristatin peptide analogs of MeVal-Val-Dil-Dap-Phe (MMAF) having a carboxylic acid equivalent at the C-terminal phenylalanine were prepared and attached to ligands through various linkers, including maleimidocaproyl-val-cit-PAB. The resulting ligand-drug conjugates were active in vitro and in vivo in inhibiting cell proliferation and are represented by the general structure of Lv-[(LU)0-1-(D)1-4]p wherein L- is Ligand unit; LU is a Linker unit (LU); v is 1; p is an number ranging from about 1 to about 20; and D is a drug moiety having the formula: wherein the moiety —N(R9)Z1 is a phenylalanine bioisostere, wherein Z1 is —CH(R10)Z2 so that the phenylalanine bioisostere has the structure of Formula A: and wherein the substituents R2-R10, X1 and Z2 are as defined.
    Type: Grant
    Filed: September 30, 2014
    Date of Patent: December 20, 2016
    Assignee: Seattle Genetics, Inc.
    Inventors: Svetlana O Doronina, Toni Beth Kline, Scott Jeffrey, Peter D Senter, Damon Meyer
  • BETA-GLUCURONIDE-LINKER DRUG CONJUGATES
    Publication number: 20160361424
    Abstract: Ligand Drug conjugate compounds comprising a ?-glucuronide-based linker and methods of using such compounds are provided.
    Type: Application
    Filed: August 24, 2016
    Publication date: December 15, 2016
    Inventor: Scott Jeffrey
  • Charging devices and methods for charging electrically powered vehicles
    Patent number: 9475393
    Abstract: Charging devices and methods for charging electrically powered vehicles are disclosed. One example charging device includes a processor configured to at least partially control a state voltage and a detection circuit coupled to the processor. The detection circuit includes an energy storage device and a discharge circuit coupled to the energy storage device. The energy storage device is configured to be charged by the state voltage. The discharge circuit is configured to discharge said energy storage device in response to a discharge command from said processor. The processor is configured to determine a charging state associated with the electrically powered vehicle based on a voltage across said energy storage device.
    Type: Grant
    Filed: June 28, 2012
    Date of Patent: October 25, 2016
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: John Kenneth Hooker, Scott Jeffrey Hall, Denis Alagic, Prerana Gajanan Kulkarni, Cecilia Maria Thomas
  • METHYLENE CARBAMATE LINKERS FOR USE WITH TARGETED-DRUG CONJUGATES
    Publication number: 20160303254
    Abstract: The present invention provides Lig-and-Drug Conjugates and Drug-Linker Compounds comprising a methylene carbamate unit. The invention provides inter alia, Ligand-Drug Conjugates, wherein the Ligand-Drug Conjugate is comprised of a Self-immolative Assembly Unit having a methylene carbamate unit for conjugation of a drug to a targeting ligand, methods of preparing and using them, and intermediates thereof. The Ligand-Drug Conjugates of the present invention are stable in circulation, yet capable of inflicting cell death once free drug is released from a Conjugate in the vicinity or within tumor cells.
    Type: Application
    Filed: December 19, 2014
    Publication date: October 20, 2016
    Inventors: Robert KOLAKOWSKI, Scott JEFFREY, Patrick BURKE
  • PYRROLOBENZODIAZEPINES AND TARGETED CONJUGATES
    Publication number: 20160287721
    Abstract: This invention relates to pyrrolobenzodiazepines (PBDs), in particular pyrrolobenzodiazepine dimers having a C2-C3 double bond and an aryl group at the C2 position in each monomer unit, and their inclusion in targeted conjugates. The differing substituent groups may offer advantages in the preparation and use of the compounds, particularly in their biological properties and the synthesis of conjugates, and the biological properties of these conjugates.
    Type: Application
    Filed: June 15, 2016
    Publication date: October 6, 2016
    Inventors: Scott JEFFREY, Patrick BURKE, Philip Wilson HOWARD
  • Using NMR Response Dependence on Gas Pressure to Evaluate Shale Gas Storage
    Publication number: 20160290942
    Abstract: A disclosed method for characterizing gas adsorption on a rock sample includes: measuring a nuclear magnetic resonance (NMR) response of the rock as a function of surrounding gas pressure along an isotherm; transforming the NMR response to obtain a Langmuir pressure distribution of gas adsorption on the rock sample; and displaying the Langmuir pressure distribution. The Langmuir pressure distribution may be shown in one dimension (e.g., contribution to signal response versus Langmuir pressure), or may be combined with additional pressure-dependencies such as spin-lattice relaxation time (T1), spin-spin relaxation time (T2), and chemical shift (?) to form a multi-dimensional distribution. The method can further include: identifying peaks in the Langmuir pressure distribution; and associating a gas storage mechanism and capacity with each peak.
    Type: Application
    Filed: March 30, 2015
    Publication date: October 6, 2016
    Applicant: Chevron U.S.A. Inc.
    Inventors: Haijing Wang, Scott Jeffrey Seltzer, Boqin Sun
  • PYRROLOBENZODIAZEPINES AND TARGETED CONJUGATES
    Publication number: 20160289239
    Abstract: A compound, or a pharmaceutically acceptable salt or solvate thereof, or conjugates thereof, selected from the group consisting of: wherein: (a) R10 is H, and R11 is OH, ORA, where RA is saturated C1-4 alkyl; (b) R10 and R11 form a nitrogen-carbon double bond between the nitrogen and carbon atoms to which they are bound; or (c) R10 is H and R11 is SOzM, where z is 2 or 3 and M is a monovalent pharmaceutically acceptable cation, or both M together are a divalent pharmaceutically acceptable cation.
    Type: Application
    Filed: June 14, 2016
    Publication date: October 6, 2016
    Inventors: Scott Jeffrey, Patrick Burke, Philip Wilson Howard