Abstract: Disclosed is a compound which has both an angiotensin-II receptor antagonistic activity and a PPAR? activation activity and is useful as a prophylactic and/or therapeutic agent for hypertension, heart diseases, angina pectoris, cerebrovascular disorders, cerebral circulatory disorders, ischemic peripheral circulatory disorders, renal diseases, arteriosclerosis, inflammatory diseases, type-2 diabetes, diabetic complications, insulin resistance syndrome, syndrome X, metabolic syndrome and hyperinsulinemia. [In the formula, A represents a 5- to 10-membered heteroaryl group; R1 and R2 independently represent a C1-6 alkyl group; and each of R3 to R5 is absent or represents H, a halogen atom, OH, NO2, a halo-C1-6 alkyl group, a (substituted) C1-6 alkoxy group, a (substituted) C3-6 cycloalkyloxy group, or a 5- to 10-membered heteroaryl group.

Abstract: To provide a novel JAK3 inhibitor that is useful as a preventive and/or therapeutic agent for rejection and graft versus host disease (GvHD) in organ transplantation, rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus, Sjögren syndrome, Behcet's disease, type I diabetes mellitus, autoimmune thyroiditis, idiopathic thrombocytopenic purpura, ulcerative colitis, Crohn's disease, asthma, allergic rhinitis, atopic dermatitis, contact dermatitis, urticaria, eczema, psoriasis, allergic conjunctivitis, uveitis, cancer, leukemia and the like. The pyridine-3-carboxyamide derivative represented by the general formula (1): or its salt or a solvate thereof.

Abstract: A lithium-ion secondary battery where a current collecting member and a foil are joined to each other securely while damage of the foil is suppressed is provided. The lithium-ion secondary battery is provided with a winding group obtained by winding a positive electrode plate and a negative electrode plate via a separator. An end portion of a positive electrode mixture non-application portion and an end portion of a negative electrode mixture non-application portion project at an upper portion and a lower portion of the winding group, respectively. Current collecting disks 7 are disposed so as to face both end faces of the winding group, respectively. The current collecting disk 7 has projecting ridge portions 8 on a face thereof opposite to the winding group and flat face portions facing the winding group at positions corresponding to the projecting ridge portions 8. The projecting ridge portions 8 are formed radially.

Abstract: There is provided a small-sized and inexpensive rotational adjustment apparatus for a linearly moveable inkjet coating head 6 without providing a rotary mechanism which is separate from and independent of a linear movement mechanism. The apparatus is capable of performing a rotational adjustment, about a rotary axis in a Z-axis direction, of the inkjet coating head in which the Z-axis direction is orthogonal to an X-axis direction which is a direction of movement of the coating head. The apparatus has: first and second moveable bodies, two in total, which are linearly moved by separate driving sources in the X-axis direction; and a converting mechanism which converts the inkjet coating head into a linear movement in the X-axis direction when the first and second moveable bodies synchronously move in the X-axis direction, and into a rotary movement, about the rotary axis of the inkjet coating head, when both the first and the second moveable bodies make a relative movement in the X-axis direction.

Abstract: A battery box structure includes a battery module, a holding frame which holds the battery module, a case which is made from expanded insulating resin and which stores the holding frame, and an elastic member secured to the holding frame and arranged between the battery module and the case, wherein the elastic member includes an upper wall and flanges extending from both side edges of the upper wall, and wherein a distance between the flanges is substantially the same as a width of a protrusion of the holding frame for securing the elastic member to the holding frame.

Abstract: There is provided an inexpensive stage which is equipped with an alignment function and is capable of easily performing high-accuracy alignment especially in a ? direction even in case an object to be processed is large in weight. The stage equipped with an alignment function has a stage main body for holding a substrate while leaving a processing surface thereof open to access. The stage is provided with: a suction means capable of sucking that surface of the substrate which lies opposite to the processing surface; a gas supply means for supplying a gas to such a region of the substrate as is other than a portion sucked by the suction means; and a drive means to give a rotating force to the suction means so that the substrate can be rotated on the same plane by causing the suction means to serve as the center of rotation.

Abstract: A method for manufacturing a solar cell, includes: forming a photoelectric converter which includes a plurality of compartment elements, and in which the compartment elements adjacent to each other are electrically connected; specifying a compartment element having a structural defect in the photoelectric converter; restricting a portion in which the structural defect exists in the compartment element by specifying a defect portion based on a resistance distribution that is obtained by measuring resistances of portions between the compartment elements adjacent to each other; and removing the structural defect by supplying a bias voltage to the portion in which the structural defect exists.

Abstract: A method for manufacturing a solar cell, includes: forming a photoelectric converter which includes a plurality of compartment elements, and in which the compartment elements adjacent to each other are electrically connected; specifying a first compartment element having a structural defect in the photoelectric converter; restricting a portion in which the structural defect exists in the first compartment element by specifying a defect portion based on a resistance distribution that is obtained by measuring resistances of portions between the compartment elements adjacent to each other; and removing or separating off the structural defect by irradiating the first compartment element and a second compartment element with a laser beam so as to intersect a boundary section between the first compartment element including the portion in which the structural defect exists and the second compartment element adjacent to the first compartment element.

Abstract: A production method, comprising a step of synthesizing silicon particle-containing silicon oxide particles by performing a gas phase reaction of monosilane gas and oxidizing gas for oxidizing the monosilane gas and a step of removing the silicon oxide with hydrofluoric acid after holding the silicon oxide particle powder in an inert atmosphere at 800-1400°, provides high-purity silicon nanoparticles which are highly practical as material powder for high-performance light-emitting elements and electronic parts in an industrial scale.

Abstract: A production method, comprising a step of synthesizing silicon particle-containing silicon oxide particles by performing a gas phase reaction of monosilane gas and oxidizing gas for oxidizing the monosilane gas and a step of removing the silicon oxide with hydrofluoric acid after holding the silicon oxide particle powder in an inert atmosphere at 800-1400° C., provides high-purity silicon nanoparticles which are highly practical as material powder for high-performance light-emitting elements and electronic parts in an industrial scale.

Abstract: A small tuner for a receiver, for example, a TV receiver is provided which requires a reduced area for mounting on a main signal board. A tuner board is disposed perpendicularly to a connector, for example, an F connector so as to allow an output signal of the tuner board to be outputted downwardly and thereby reduce the area required to mount the tuner. With the tuner made smaller and more immune to noise, a portion facing the tuner board of the shield case for the tuner is removed and a ground pattern is formed over the tuner board surface facing the removed portion of the tuner case. The core line of the F connector is bent to be connected to an end portion of the tuner board so as to facilitate laying out the tuner board.

Abstract: A method for conveniently detecting binding between the von Willebrand factor and glycoprotein Ib and a means to be used therein. The von Willebrand factor fixed in a reactor immobilized in a reaction vessel in the presence of bottrocetin is bound to a chimeric protein constructed by fusing the carboxyl terminal of a partial protein containing the von Willebrand factor-binding site of glycoprotein Ib with the amino terminal of the Fc region of an immunoglobulin molecule. Then the Fc region of the above immunoglobulin molecule is detected to thereby detect the binding between the von Willebrand factor and the glycoprotein Ib or inhibition of this binding.

Abstract: The present invention relates a specific tetrahydroisoquinoline compound which is useful as a chemokine receptor type 3 (CCR3) antagonist, and a pharmaceutical composition comprising the same as an active ingredient. The tetrahydroisoquinoline compound of the present invention is useful for the treatment or prevention of a disease in which CCR3 participates.

Abstract: A battery box housing a battery is mounted between left and right side frames extending in a longitudinal direction of a vehicle body so that the battery box is offset to a left side of the vehicle body, and an intake duct and an exhaust duct for cooling air for cooling the battery are connected to an end of the battery box on a right side of the vehicle body. Therefore, it is possible not only to protect the battery between the left and right frames from a shock caused upon a side collision, but also to ensure a space for disposition of the intake duct and the exhaust duct while ensuring a volume of the battery box to the maximum. Moreover, the battery box is connected at its left and right ends to the left and right side frames.

Abstract: A method for conveniently detecting binding between the von Willebrand factor and glycoprotein Ib and a means to be used therein. The von Willebrand factor fixed in a reactor immobilized in a reaction vessel in the presence of bottrocetin is bound to a chimeric protein constructed by fusing the carboxyl terminal of a partial protein containing the von Willebrand factor-binding site of glycoprotein Ib with the amino terminal of the Fc region of an immunoglobulin molecule. Then the Fc region of the above immunoglobulin molecule is detected to thereby detect the binding between the von Willebrand factor and the glycoprotein Ib or inhibition of this binding.

Abstract: A battery module is configured so that the first cell string and the second cell string are arranged between the first plate member and the second plate member and the second cell string is arranged closer to the second plate member side than the first cell string is and is arranged closer to the outlet side than the first cell string is. At the inlet side of the housing, the inlet is arranged closer to the first plate member than to the second cell string, at least a part between the inlet side of the second cell string and the second plate member is covered by the inlet-side guide plate, and the cooling air is introduced into the housing through the inlet so as to form a flow of the cooling air along the first plate member and a flow of the cooling air along the inlet-side guide plate.

Abstract: A cell module has a cell group with a plurality of cells connected to each other. The module comprises a bus bar plate including a bus bar connecting between the cells and an end cover for covering the bus bar plate. The cell module is configure to be fixed with the end cover.

Abstract: A preserving apparatus for preserving welded joint portions 7, 8 by deposit welding on the inner surface of the welded joint portions 7, 8, in which a nozzle 4 and a pipe 5 supported under water are joined, the apparatus having: a seal member 9 that is disposed in front and behind the welded joint portions 7, 8 to be deposit welded within the nozzle 4 and pipe 5, and serves to demarcate and form a closed operation area A within the nozzle 4 and pipe 5; water drainage means 12 for draining the inside of the operation area A demarcated and formed by the seal member 9 and obtaining a gas atmosphere therein; and welding means 13 for deposit welding on the inner surface of the welded joint portions 7, 8 within the operation area A in which the gas atmosphere has been created.

Abstract: In order to reduce the number of processes for manufacturing spacers and to prevent quality degradation resulting from a cell gap, a spacer 115 in a semi-transmission area 12 is formed outside of a region of a bump layer 118B. Thus, it is made possible to manufacture the spacer in the transmission region 11 and the spacer outside of the region of the bump layer in the same process. Accordingly, the number of processes can be reduced. Moreover, it is made possible to determine the cell gap in the semi-transmission area 12 by a single element of a spacer. Accordingly, precision degradation of the cell gap, which results from the bump layer, can be prevented, and high display quality can be obtained.