Patents by Inventor Seth Grant
Seth Grant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230278987Abstract: The application is directed to compounds that are active as antibacterial agents. The compounds are active against gram-positive and gram-negative bacteria and can be used to treat infections caused by gram-positive and gram-negative bacteria. Also disclosed are processes for making the compounds.Type: ApplicationFiled: November 12, 2020Publication date: September 7, 2023Inventors: Paul R. Sebahar, Ryan E. LOOPER, Charles A. TESTA, Benlsaac C. TRESCO, Travis J. HAUSSENER, Hariprasada R. Kanna REDDY, Seth GRANT
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Patent number: 11702145Abstract: A vehicle body structure has a vehicle frame structure, a cabin structure, a cargo area structure and an elastic bumper element. The cabin structure is installed to a forward portion of the vehicle frame structure and defines a passenger compartment. The cabin structure also has a rearward wall. The cargo area structure is installed to a rearward portion of the vehicle frame structure. The cargo area structure has a forward wall spaced apart from the rearward wall of the cabin structure. The elastic bumper element is installed to one of the rearward wall or the forward wall such that in response to flexing of the vehicle frame structure, the elastic bumper element can contact the other of the rearward wall or the forward wall thereby restricting direct contact between the rearward wall and the forward wall.Type: GrantFiled: June 30, 2021Date of Patent: July 18, 2023Assignee: NISSAN NORTH AMERICA, INC.Inventors: Gregory Byrne, Jeffrey Pencak, Seth Grant, Brian Salazar
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Publication number: 20230159491Abstract: The invention is directed to compounds that are active as antibacterial agents. The invention compounds are active against gram-positive and gram-negative bacteria and can be used to treat infections caused by gram-positive and gram-negative bacteria. Also disclosed are processes and intermediates for making the compounds.Type: ApplicationFiled: January 15, 2020Publication date: May 25, 2023Inventors: Ryan E. Looper, Paul Sebahar, Hariprasada R. Kanna Reddy, Travis J. Haussener, Charles A. Testa, Benlsaac C. Tresco, Seth Grant, Carmela Napolitano, Fabio Maria Sabbatini
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Publication number: 20230072397Abstract: The invention is directed to compounds that are active as antibacterial agents. The invention compounds are active against gram-positive and gram-negative bacteria and can be used to treat infections caused by gram-positive and gram-negative bacteria. Also disclosed are processes and intermediates for making the compounds.Type: ApplicationFiled: January 15, 2020Publication date: March 9, 2023Inventors: Ryan E. Looper, Paul Sebahar, Hariprasada R. Kanna Reddy, Travis J. Haussener, Charles A. Testa, Benlsaac C. Tresco, Seth Grant, Carmela Napolitano, Fabio Maria Sabbatini
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Publication number: 20230001989Abstract: A vehicle body structure has a vehicle frame structure, a cabin structure, a cargo area structure and an elastic bumper element. The cabin structure is installed to a forward portion of the vehicle frame structure and defines a passenger compartment. The cabin structure also has a rearward wall. The cargo area structure is installed to a rearward portion of the vehicle frame structure. The cargo area structure has a forward wall spaced apart from the rearward wall of the cabin structure. The elastic bumper element is installed to one of the rearward wall or the forward wall such that in response to flexing of the vehicle frame structure, the elastic bumper element can contact the other of the rearward wall or the forward wall thereby restricting direct contact between the rearward wall and the forward wall.Type: ApplicationFiled: June 30, 2021Publication date: January 5, 2023Inventors: Gregory BYME, Jeffrey PENCAK, Seth GRANT, Brian SALAZAR
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Patent number: 8975291Abstract: Herein are disclosed indoles of formula (I) where the various groups are defined herein, and which are useful for treating cancer.Type: GrantFiled: August 7, 2013Date of Patent: March 10, 2015Assignee: GlaxoSmithKline LLCInventors: James Brackley, III, Joelle Lorraine Burgess, Seth Grant, Neil Johnson, Steven D. Knight, Louis Lafrance, William H. Miller, Kenneth Newlander, Stuart Romeril, Meagan B. Rouse, Xinrong Tian, Sharad Kumar Verma
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Publication number: 20130345200Abstract: Herein are disclosed indoles of formula (I) where the various groups are defined herein, and which are useful for treating cancer.Type: ApplicationFiled: August 7, 2013Publication date: December 26, 2013Applicant: GlaxoSmithKline LLCInventors: James Brackley, III, Joelle Lorraine Burgess, Seth Grant, Neil Johnson, Steven D. Knight, Louis Lafrance, William H. Miller, Kenneth Newlander, Stuart Romeril, Meagan B. Rouse, Xinrong Tian, Sharad Kumar Verma
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Publication number: 20130053397Abstract: Herein are disclosed indoles of formula (I) where the various groups are defined herein, and which are useful in treating cancer.Type: ApplicationFiled: May 5, 2011Publication date: February 28, 2013Inventors: James Brackley, III, Joelle Lorraine Burgess, Seth Grant, Neil Johnson, Steven D. Knight, Louis Lafrance, William H. Miller, Kenneth Newlander, Stuart Romeril, Meagan B. Rouse, Xinrong Tian, Sharad Kumar Verma
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Publication number: 20050003477Abstract: The present invention provides an isolated nucleic acid molecule encoding a brain cyclic nucleotide gated ion channel (BCNG) protein. An isolated BCNG protein is also provided as is a composition comprising a BCNG encoding nucleic acid or protein or a portion thereof. The present invention also provides a method of identifying an ion channel subunit related protein encoding nucleic acid molecule in a sample. The invention further provides a method for evaluating the ability of a compound to modulate an ion channel associated neurological, cardia, or renal condition. The invention also provides a method for evaluating the ability of a compound to interact with a BCNG-related ion channel subunit protein. Additionally, the present invention provides a method for identifying a compound capable of modulating the activity of a BCNG-related protein. The present invention additionally provides a method of treating a cardiac, renal or neurological condition.Type: ApplicationFiled: March 6, 2003Publication date: January 6, 2005Applicant: The Trustees of Columbia University in the City of New YorkInventors: Eric Kandel, Bina Santoro, Dusan Bartsch, Steven Siegelbaum, Gareth Tibbs, Seth Grant
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Publication number: 20040142421Abstract: The present invention provides an isolated nucleic acid encoding a BCNG protein or a portion thereof or BCNG-related protein or a portion thereof. The present invention further provides a method for identifying a nucleic acid in a sample which encodes a BCNG protein or a BCNG-related protein. The present invention also provides a method for testing whether a compound affects the expression of a BCNG protein or a BCNG-related protein. In addition, the present invention further provides a method for identifying a compound capable of interacting with a BCNG protein or a BCNG-related protein. Also, the present invention provides a method for identifing a compound capable of modulating BCNG protein or BCNG-related protein activity. Further, the present invention also provides a method of treating a condition in a subject which comprises administering to the subject an amount of the provided compound, effective to treat the condition.Type: ApplicationFiled: January 7, 2004Publication date: July 22, 2004Applicant: The Trustees of Columbia University in the City of New YorkInventors: Eric Kandel, Bina Santoro, Dusan Bartsch, Steven Siegelbaum, Gareth Tibbs, Seth Grant
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Patent number: 6703485Abstract: The present invention provides an isolated nucleic acid encoding a BCNG protein or a portion thereof or BCNG-related protein or a portion thereof. The present invention further provides a method for identifying a nucleic acid in a sample which encodes a BCNG protein or a BCNG-related protein. The present invention also provides a method for testing whether a compound affects the expression of a BCNG protein or a BCNG-related protein. In addition, the present invention further provides a method for identifying a compound capable of interacting with a BCNG protein or a BCNG-related protein. Also, the present invention provides a method for identifing a compound capable of modulating BCNG protein or BCNG-related protein activity. Further, the present invention also provides a method of treating a condition in a subject which comprises administering to the subject an amount of the provided compound, effective to treat the condition.Type: GrantFiled: May 28, 1998Date of Patent: March 9, 2004Assignee: The Trustees of Columbia University in the City of New YorkInventors: Eric R. Kandel, Bina Santoro, Dusan Bartsch, Steven Siegelbaum, Gareth Tibbs, Seth Grant
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Publication number: 20030118988Abstract: The present invention provides an isolated nucleic acid encoding a BCNG protein or a portion thereof or BCNG-related protein or a portion thereof. The present invention further provides a method for identifying a nucleic acid in a sample which encodes a BCNG protein or a BCNG-related protein. The present invention also provides a method for testing whether a compound affects the expression of a BCNG protein or a BCNG-related protein. In addition, the present invention further provides a method for identifying a compound capable of interacting with a BCNG protein or a BCNG-related protein. Also, the present invention provides a method for identifing a compound capable of modulating BCNG protein or BCNG-related protein activity. Further, the present invention also provides a method of treating a condition in a subject which comprises administering to the subject an amount of the provided compound, effective to treat the condition.Type: ApplicationFiled: May 28, 1998Publication date: June 26, 2003Inventors: ERIC R. KANDEL, BINA SANTORO, DUSAN BARTSCH, STEVEN SIEGELBAUM, GARETH TIBBS, SETH GRANT
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Patent number: 6551821Abstract: The present invention provides an isolated nucleic acid molecule encoding a brain cyclic nucleotide gated ion channel (BCNG) protein. An isolated BCNG protein is also provided as is a composition comprising a BCNG encoding nucleic acid or protein or a portion thereof. The present invention also provides a method of identifying an ion channel subunit related protein encoding nucleic acid molecule in a sample. The invention further provides a method for evaluating the ability of a compound to modulate an ion channel associated neurological, cardia, or renal condition. The invention also provides a method for evaluating the ability of a compound to interact with a BCNG-related ion channel subunit protein. Additionally, the present invention provides a method for identifying a compound capable of modulating the activity of a BCNG-related protein. The present invention additionally provides a method of treating a cardiac, renal or neurological condition.Type: GrantFiled: December 23, 1997Date of Patent: April 22, 2003Assignee: The Trustees of Columbia University in the City of New YorkInventors: Eric R. Kandel, Bina Santoro, Dusan Bartsch, Steven Siegelbaum, Gareth Tibbs, Seth Grant