Abstract: Applications of different configurations of novel glucagon peptide 1 with fatty acid modification or nonmodification in the treatment of T2D or the pancreas protection are provided. The dimer of the present disclosure is formed by two identical cysteine-containing GLP-1 monomers through a disulfide bond. The H-like GLP-1 homodimer (disulfide bond is inside chains) showed remarkable increase in hypoglycemic duration without reducing specific activity. The GLP-1 dimer provided has an in-vivo effective duration of up to 19 days, which significantly prolonged compared with that of the positive control drug Liraglutide with 3 days of effective duration, or thereby greatly promoting the technical advancement in long-acting GLP-1 drugs and facilitating their clinical applications and business. Meanwhile the U-like homodimer (disulfide bond is at the C-terminus) does not affect blood glucose, but can obviously protect pancreatic exocrine cells such as acini and ducts, and improve pancreas function.

Abstract: The present disclosure relates to an organic electroluminescent device. The organic electroluminescent device of the present disclosure shows high luminous efficiency and good lifespan by comprising a specific combination of the plural kinds of host compounds and a specific hole transport compound.

Abstract: A docker image is received. The docker image is for a container. The container contains files that allow for virtualization of applications that run within the container. The docker image is parsed to identify layer files in the docker image. Installed software components (e.g., installed files) and/or hardware components in the layer files are identified. Software application index calls are made to generate information that identifies relationships between the installed software components and/or hardware components. The relationships between the installed software components and/or hardware components are then displayed to a user.

Abstract: A heat pipe integrated thermal battery (“HITB”) is provided that may include a storage tank, a thermal storage medium within the storage tank, a guide tube extending within the storage tank and through at least one end of the storage tank, and a heat pipe configured to be movable within the guide tube. The heat pipe may be configured to discharge heat to and absorb heat from the thermal storage medium within the storage tank.

Abstract: Provided is an electronic device including processing circuitry configured to generate at least one signal according to a first communication protocol by referencing a lookup table, the lookup table including simulation waveform information, and the simulation waveform information simulating a second communication protocol different from the first communication protocol, and transmit the at least one signal, the at least one signal including a data packet.

Abstract: A multi-functional massager, including a foot massage mechanism and a leg massage mechanism; the foot massage mechanism has a foot massage assembly provided within a first housing to provide foot massage, and the leg massage mechanism has two adjacent slots formed within a second housing; massage airbags are provided in the slots; two sides of the second housing is rotatably connected to two side surfaces of the first housing. Accordingly, simultaneous foot and leg massage can be achieved, and the massager can be folded in a storage position to form a footstool.

Abstract: The present invention provides a device for enrichment culture and gravity-type isolation of marine microorganisms in a high-pressure environment. The device includes an enrichment and multistage purification unit and a gravity-type isolation and culture unit. Under a high-pressure and low-temperature environment constructed to be consistent with a marine environment, the enrichment and multistage purification unit is used for realizing a process of enrichment and multistage purification of the marine microorganisms, obtaining a marine microorganism enrichment bacteria liquid and injecting the marine microorganism enrichment bacteria liquid into the gravity-type isolation and culture unit. The gravity-type isolation and culture unit is used for carrying out automatic streaking by means of gravity in the high-pressure environment to achieve solid isolation and culture of the marine microorganisms, such that culturability of the marine microorganisms is effectively improved.

Abstract: An automatic cleaning device includes a mobile platform, a lifting station, a cleaning module, a liquid supplying module, and a collecting module. The mobile platform is configured to automatically move in a target direction on a surface to be cleaned. The lifting station is connected to the mobile platform and configured to move upwards or downwards with respect to the mobile platform. The cleaning module is connected to the lifting station and configured to clean the surface to be cleaned; the liquid supplying module is configured to provide cleaning liquid to the surface to be cleaned; and the collecting module is configured to collect the cleaning liquid. A height of the cleaning module of the automatic cleaning device is adjustable, and the automatic cleaning device has a great cleaning strength and is capable of collecting dirty cleaning liquid, thus, the automatic cleaning device can be applied broadly.

Abstract: The disclosure relates to a protein-type nanoparticle for multi-specific antibody delivery, a preparation method, and its application. The protein-type nanoparticle includes a polyester and a protein with a hydrophobic domain, and the hydrophobic domain of the protein is bound with the polyester through hydrophobic interactions. The protein is at least one of albumin, globulin and cell wall protein. The protein-type nanoparticle of the present disclosure has excellent stability and biocompatibility. The protein-type nanoparticle is used to prepare a multi-specific antibody delivery platform (?Fc-NP) by binding anti-IgG-Fc antibody or anti-IgG-Fc antibody fragment, which can stably, quickly and easily bind to multiple specific antibodies through antigen-antibody interaction and enhance the therapeutic effect of specific antibodies.

Abstract: A water treatment composition is disclosed herein comprising a nonylphenol resin and a polyethoxylated tallow amine.

Abstract: The present disclosure is directed to alcohol and amine containing exatecan derivatives, and pharmaceutically acceptable salts or solvates thereof, comprising a structure of formula I: wherein X is defined in the disclosure. The disclosure is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of cancers and/or tumors.

Abstract: The present invention relates to a surface-treated copper foil, which has excellent adhesive strength with a resin substrate, shows low bending deformation after adhesion with a resin substrate, and is suitable as a high-frequency foil due to its low transmission loss, to a copper clad laminate comprising same, and to a printed wiring board.

Abstract: The present invention disclosure also relates to a pharmaceutical composition that ccomprises the compound as an active ingredient.

Abstract: An identity certificate may be issued to a blockchain node. The issuance may include issuing a first identity certificate to a first terminal and receiving a second identity certificate issuance request that is from the first terminal. A second identity certificate may be issued to the first terminal, and a third identity certificate issuance request is received from the second terminal. A third identity certificate is issued to the second terminal, so that the second terminal forwards the third identity certificate to the third terminal.

Abstract: A display device include a substrate, a pixel electrode disposed on the substrate, a partition layer disposed on the substrate and defining an opening exposing at least a part of the pixel electrode, a light-emitting layer disposed on the pixel electrode within the opening of the partition layer, a common electrode disposed on the light-emitting layer within the opening of the partition layer, a capping layer disposed on the common electrode and the partition layer, and surrounding a side surface of the opening of the partition layer, and a color conversion pattern disposed on the capping layer within the opening of the partition layer.

Abstract: Provided are a display panel and a method for manufacturing the same, a display device and a control method of the same related to the technical field of display. The display panel includes a base substrate; a pixel defining layer arranged on the base substrate and configured to define a plurality of sub-pixels, at least one sub-pixel of the plurality of sub-pixels includes a plurality of sub-pixel-units; and each sub-pixel-unit of the plurality of sub-pixels includes an anode, a light emitting layer, and a cathode that are stacked, and anodes of adjacent sub-pixel-units in a same sub-pixel are insulated from each other and are apart from the base substrate for different distances.

Abstract: The present disclosure relates to an organic electroluminescent device. The organic electroluminescent device of the present disclosure shows high luminous efficiency and good lifespan by comprising a specific combination of the plural kinds of host compounds and a specific hole transport compound.

Abstract: The present disclosure provides an array substrate and a liquid crystal display panel, belonging to the file of display technology. The array substrate includes a base substrate, a first electrode, an insulating dielectric layer and a second electrode stacked in sequence; the second electrode is provided with at least one hollow hole, and the hollow hole is in a shape of convex polygon, circle or ellipse.

Abstract: The disclosure provides a speech control method, a speech control apparatus, an electronic device, and a storage medium. The method includes: acquiring target audio data sent by a client, the target audio data including audio data collected by the client within a target duration before wake-up and audio data collected by the client after wake-up; performing speech recognition on the target audio data; and controlling the client based on an instruction recognized from a second audio segment of the target audio data in response to recognizing a wake-up word from a first audio segment at beginning of the target audio data; in which, the second audio segment is later than the first audio segment or has an overlapping portion with the first audio segment.