Abstract: An optical fiber interface is configured to connect to an optical fiber patch cable plug, and includes: a main body, where a plug-in port for insertion is disposed on the main body, and the plug-in port is configured to accommodate an inserted optical fiber patch cable plug; a cover plate, where the cover plate is disposed above the main body and is fixed to the main body; and a clamping unlocking mechanism, where the clamping unlocking mechanism is disposed between the plug-in port and the cover plate and includes a clamping component and an elastic component, the clamping component is disposed in a radial direction of the plug-in port and is configured to clamp the optical fiber patch cable plug when the optical fiber patch cable plug is inserted into the plug-in port. The optical fiber interface provided in embodiments of this application can be used for optical fiber connection.

Abstract: In some embodiments, an electronic device displays suggested routes based on the characteristics of respective vehicles. In some embodiments, an electronic device receives data for respective vehicles from a source external to the electronic device. In some embodiments, an electronic device anonymizes a vehicle identifier and determines customized suggested routes using the anonymized vehicle identifier.

Abstract: A preparation method of the microcapsules for low-temperature well cementation to be used to control cement hydration heat includes: (S1) a shell material, and added into deionized water, then the resultant mixture being stirred in a thermostat water bath so as to completely dissolve it into a homogeneous and stable shell material solution; (S2) a core material and an emulsifier being put into a three-necked flask and stirred in a thermostat water bath so as to uniformly emulsify and disperse them, forming a stable oil-in-water core material emulsion, while adjusting the pH value of the emulsion with a pH adjuster; (S3) the three-necked flask containing the core material emulsion being transferred to a water bath, and then the shell material solution being dropwise added into it with stirring, after reacting, a solid-liquid mixture being poured out so as to naturally cool it to room temperature.

Abstract: An unit narrow board glue application device and method suitable for high-frequency hot pressing of solid wood edge glued panel is disclosed, including a transverse chain feeding device, a longitudinal roller feeding device and a gluing device. The transverse chain feeding device includes a fixed chain transport mechanism and a movable chain transport mechanism. The longitudinal roller feeding device includes the lifting power roller assembly, the longitudinal feed roller assembly and the pneumatic compression roller assemblies. The gluing device includes a glue pump, a glue application head, and a pneumatic slide table. The front end face of the hollow structure glue application head has a number of small round holes for glue liquid discharge and horizontal glue guiding grooves. The disclosure has a high degree of automation, can give full play to the efficiency of the high-frequency hot press, and is conducive to the intelligent manufacturing of solid wood furniture.

Abstract: Systems and methods for predicting a risk of cardiovascular disease (CVD) from one or more fundus images are disclosed. Fundus images associated with an individual are processed to determine whether fundus images are of sufficient quality. The fundus images of sufficient quality are processed to identify fundus images belonging to a single eye. A plurality of risk contributing factor sets of CNNs (RCF CNN) are configured to output an indicator of probability of the presence of a different risk contributing factor in each of the one or more fundus images. At least one of the RCF CNNs is configured in a jury system model having a plurality of jury member CNNs, each being configured to output a probability of a different feature in the one or more fundus images. The outputs of the jury member CNNs are processed to determine the indicator of probability of the presence of the risk contributing factor output by the RCF CNN.

Abstract: The invention provides novel imidazole pyrazole derivatives having the general formula (I), and pharmaceutically acceptable salts thereof, wherein R1-R7 are as described herein: Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.

Abstract: The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing one or more disease states that could benefit from inhibition of plasma kallikrein, including hereditary angioedema, uveitis, posterior uveitis, wet age related macular edema, diabetic macular edema, diabetic retinopathy and retinal vein occlusion. The compounds are selective inhibitors of plasma kallikrein.

Abstract: A display assembly, includes: a first substrate and a second substrate that are disposed opposite, a first liquid crystal layer located between the first substrate and the second substrate, a third substrate disposed at a side of the first substrate away from the second substrate, a second liquid crystal layer located between the first substrate and the third substrate, a first pixel circuit layer disposed between the first substrate and the first liquid crystal layer, a second pixel circuit layer disposed between the third substrate and the second liquid crystal layer, a polarizing device disposed on a side of the second pixel circuit layer away from the second liquid crystal layer, and a first metal wire grid polarizing layer disposed between the first substrate and the first pixel circuit layer. The first metal wire grid polarizing layer is electrically insulated from the first pixel circuit layer.

Abstract: A method for evaluating a speech forced alignment model, an electronic device, and a storage medium are provided. The method includes: according to each audio segment in a test set and a text corresponding to each audio segment, acquiring, by using a speech forced alignment model to be evaluated, a phoneme sequence corresponding to each audio segment and a predicted start time and a predicted end time of each phoneme in the phoneme sequence; for each phoneme, obtaining a time accuracy score of the phoneme according to the predicted start time and the predicted end time of the phoneme and a predetermined reference start time and a predetermined reference end time of the phoneme; and determining a time accuracy score of said speech forced alignment model according to the time accuracy score of each phoneme.

Abstract: An optical port shielding and fastening apparatus is configured to be installed in the optical module. The optical module includes a housing assembly and an optical component located in the housing assembly. The optical port shielding and fastening apparatus includes a fastener and an electromagnetic wave absorbing piece. The fastener is fastened in the housing assembly. The electromagnetic wave absorbing piece is fastened on a side that is of the fastener and that faces an outside of the housing assembly. A first mounting hole and a second mounting hole are correspondingly provided on the fastener and the electromagnetic wave absorbing piece. The optical component passes through the first mounting hole and the second mounting hole in sequence. This application provides an optical port shielding and fastening apparatus, an optical module, and a communications device, to resolve poor optical port shielding performance of an optical module in the related technology.

Abstract: Provided herein are anti-LAP antibodies (e.g., recombinant humanized, chimeric, and human anti-LAP antibodies) or antigen binding fragments thereof which have therapeutically beneficial properties, such as binding specifically to LAP-TGF?1 on cells but not to LAP-TGF?1 in extracellular matrix, as well as compositions including the same. Also provided are uses of these antibodies or antigen binding fragments in therapeutic applications, such as in the treatment of cancer, and diagnostic applications.

Abstract: A heat dissipation assembly includes: a heat spreader, configured to be in contact with an element; a frame body, configured to limit a position of the heat spreader, where the frame body surrounds a side wall of the heat spreader; and an elastic structure, fixedly connected to the frame body. In this application, the heat spreader is disposed, so that heat generated by the element can be evenly conducted; furthermore, the elastic structure fixedly connected to the frame body is disposed, so that the element, the heat spreader, and the frame body are reliably fastened in a thickness direction, to ensure that heat generated by the element can be smoothly conducted. In addition, because a requirement on adhesion strength of a heat conducting material is reduced, a heat conducting material with better heat dissipation performance can be selected, thereby further improving and heat dissipation efficiency of a chip is further improved.

Abstract: An approach for the task-oriented user guidance is provided. The approach comprises receiving a query from a user to accomplish a task utilizing an application. The approach comprises determining one or more related pages of the application, wherein one or more keywords of the one or more related pages of the application match with one or more keywords of the query. The approach further comprises determining possible paths passing the one or more related pages of the application based on page relationship of the application. The approach further comprises determining one or more paths from the possible paths according to weights of the paths. The approach further comprises presenting the one or more paths to the user. The keywords of the page, the page relationship and the weights of the paths are determined based on page information of the application.

Abstract: The invention provides novel heterocyclic compounds having the general formula (I), and pharmaceutically acceptable salts thereof, wherein R1 to R9 and p are as described herein: Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.

Abstract: The present invention relates to novel therapeutic agents against hepatitis B virus (HBV) infection, particularly inhibitors of viral covalently closed circular DNA (cccDNA) which is the key barrier for HBV cure. Accordingly, the invention provides the pyrrolo[2,3-b]pyrazine compounds of formula (I), as described and defined herein, for use in the treatment of HBV infection. The compounds provided herein are highly potent against HBV infection and enable an improved therapy, particularly of chronic HBV infection and HBV rebound. The present invention further relates to a novel screening assay for the identification of therapeutic agents against HBV infection, particularly cccDNA inhibitors, which is performed in hepatocyte-like cells that recapitulate the complete HBV life cycle following infection with patient-derived HBV.

Abstract: The invention provides novel imidazole pyrazole derivatives having the general formula (I), and pharmaceutically acceptable salts thereof, wherein A and R1-R7 are as described herein: Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.

Abstract: A sealed assembly for pill crushing and delivering and a method for using thereof are provided. The assembly includes: a connecting valve with different diameters, including a first end, a valve and a second end provided with a syringe-abutting interface, wherein, an opening diameter of the first end is larger than that of the second end; and a pill-crushing carrier including a sealed cavity having only one filling-in opening, the pill-crushing carrier has a first state when separated from the connecting valve and the filling-in opening is exposed for delivering pills into the carrier, and a second state when the filling-in opening is connected to the first end of the connecting valve, crushed and dissolved pill powders in the sealed cavity can be taken out through the connecting valve. The assembly can crush pills and dissolve powders in a sealed cavity, deliver powder-dissolved liquid and prevent powders from dispersing.

Abstract: A micro light-emitting device includes an epitaxial structure and a bridge connection structure. The epitaxial structure includes a first mesa surface and a second mesa surface which are located on the same side of the epitaxial structure with a height difference therebetween, which have the same widths in a first direction, and which respectively have center points in the first direction that are aligned in a second direction perpendicular to the first direction. The bridge connection structure includes a first bridge connection layer that is formed on the first and second mesa surfaces so as to be symmetrically disposed on at least one of the first and second mesa surfaces with a line of symmetry thereof being in the second direction and passing through the center points of the first and second mesa surfaces. A method for making the same, and a light-emitting apparatus including the same are also disclosed.

Abstract: The invention provides novel imidazopyrazine derivatives having the general formula (I), and pharmaceutically acceptable salts thereof, wherein X1 to X4, R1 to R5, R8 to R10, A, and L1 are as described herein: Further provided are pharmaceutical compositions including the compounds, processes of manufacturing the compounds and methods of using the compounds as medicaments, in particular methods of using the compounds as antibiotics for the treatment or prevention of bacterial infections and resulting diseases.