Patents by Inventor Steffen Ernst

Steffen Ernst has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diagnostic kit for detecting immunogenic response and method of screening
    Publication number: 20030119066
    Abstract: The present invention relates to a kit for predicting binding of specific antibodies to potential immunogens. The kit comprises antigenic peptide sequences having less than 26 amino acids, said antigenic peptide sequences being capable of binding antibodies specific for structural epitopes contained on potential immunogens. The antigenic peptide sequences are immobilized on a solid support.
    Type: Application
    Filed: October 4, 2002
    Publication date: June 26, 2003
    Applicant: Novozymes A/S
    Inventors: Erwin Ludo Roggen, Nina Teeres Nilsson, Steffen Ernst, Shamkant Anant Patkar, Esben Peter Friis
  • Modified polypeptides
    Publication number: 20030087785
    Abstract: The present invention relates to polypeptides with reduced immune response including reduced allergenicity having one or more amino acid residues being substituted with other amino acid residues and/or having coupled one or more polymeric molecules in the vicinity of the polypeptides metal binding site, a method for preparing modified polypeptides of the invention, the use of the polypeptide for reducing the immunogenicity and allergenicity and compositions comprising the polypeptide.
    Type: Application
    Filed: August 1, 2002
    Publication date: May 8, 2003
    Applicant: Novozymes A/S
    Inventors: Arne Agerlin Olsen, Claus von der Osten, Kim Vilbour Andersen, Steffen Ernst, Erwin Ludo Roggen
  • Cellulose films for screening
    Publication number: 20030049707
    Abstract: The invention relates to a ellulose film comprising microfibrillated cellulose and to the use of it for screening of a biological compound and nucleic acids encoding a biological compound.
    Type: Application
    Filed: May 20, 2002
    Publication date: March 13, 2003
    Applicant: Novozymes A/S
    Inventors: William Helbert, Martin Schulein, Hanne Dela, Henri Dominique Chanzy, Steffen Ernst, Tommy Lykke Husum, Lars Kongsbak
  • Method for the assessment of allergenicity
    Publication number: 20030032072
    Abstract: The invention relates to a method for the assessment of the allergenicity or the toxicity of a test compound and for the screening of at least two compounds simultaneously. The invention also relates to a method of characterizing a cell type for the present invention, as well as an assay kit for the high through-put screening of a compound. By contacting a cell culture of at least one cell type of animal origin with the test compound and measuring cytokine responses, the allergenicity of the test compound can be assessed.
    Type: Application
    Filed: September 25, 2002
    Publication date: February 13, 2003
    Applicant: Novozymes A/S
    Inventors: Erwin Ludo Roggen, Steffen Ernst
  • Modified polypeptide
    Patent number: 6461849
    Abstract: The present invention relates to polypeptides with reduced immune response including reduced allergenicity having one or more amino acid residues being substituted with other amino acid residues and/or having coupled one or more polymeric molecules in the vicinity of the polypeptides metal binding site, a method for preparing modified polypeptides of the invention, the use of the polypeptide for reducing the immunogenicity and allergenicity and compositions comprising the polypeptide.
    Type: Grant
    Filed: October 13, 1999
    Date of Patent: October 8, 2002
    Assignee: Novozymes, A/S
    Inventors: Arne Agerlin Olsen, Claus von der Osten, Kim Vilbour Andersen, Steffen Ernst, Erwin Ludo Roggen
  • Cellulose films for screening
    Patent number: 6426189
    Abstract: The invention relates to a cellulose film comprising microfibrillated cellulose and to the use of it for screening of a biological compound and nucleic acids encoding a biological compound.
    Type: Grant
    Filed: September 29, 2000
    Date of Patent: July 30, 2002
    Assignee: Novozymes A/S
    Inventors: William Helbert, Henri Dominique Chanzy, Steffen Ernst, Martin Schulein, Tommy Lykke Husum, Lars Kongsbak
  • High throughput screening (HTS) assays
    Publication number: 20020019009
    Abstract: The present invention is to provide a method to perform assays that efficiently and accurately can screen large numbers of cell populations producing variants of a molecule of interest.
    Type: Application
    Filed: December 8, 2000
    Publication date: February 14, 2002
    Inventors: Erwin Ludo Roggen, Steffen Ernst, Henrik Pedersen
  • Rationally designed polysaccharide lyases derived from heparinase I
    Patent number: 6217863
    Abstract: Modified heparinases having altered binding specificity and activity are provided. Isolated nucleic acids encoding the same as as vectors and host cells are provided. Methods for using the modified heparinases are also provided.
    Type: Grant
    Filed: January 19, 1999
    Date of Patent: April 17, 2001
    Assignee: Massachusetts Institute of Technology
    Inventors: Ranganathan Godavarti, Ram Sasisekharan, Steffen Ernst, Ganesh Venkataraman, Charles L. Cooney, Robert Langer