Abstract: Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3? or C4? modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.

Abstract: A computing system including a processor and a memory, which includes a first memory region operating as a kernel space and a second memory region operating as a user space. Maintained within the kernel space, a first logic unit receives a notification identifying a newly created thread and extracts at least meta-information associated with the newly created thread. Maintained within the user space, a second logic unit receives at least the meta-information associated with the newly created thread and conducts analytics on at least the meta-information to attempt to classify the newly created thread. An alert is generated by the second logic unit upon classifying the newly created thread as a cyberattack associated with a malicious position independent code execution based at least on results of the analytics associated with the meta-information associated with the newly created thread.

Abstract: A convertible luggage having a removable wheel assembly is disclosed. The convertible luggage includes a body with adaptors rotatably connected to the basement portion of the body. The adaptors have a solid cylindrical form-factor and are provided with a pair of sockets and pressable buttons along the side portions. Wheel assemblies removably connected to the adaptors are provided. The first end of the wheel assembly is fitted with a wheel and the second end of the wheel assembly comprises a connector having a hollow cylindrical form factor. The connector is provided with a pair of extrusions and a pair of openings along the side portions. The pair of extrusions provided on the connector locks into the pair of sockets provided on the adaptors, and the pair of openings provided on the connector locks into the pair of pressable buttons provided on the adaptors.

Abstract: Electromechanical polymer (EMP) actuators are used to create haptic effects on a user interface deface, such as a keyboard. The keys of the keyboard may be embossed in a top layer to provide better key definition and to house the EMP actuator. Specifically, an EMP actuator is housed inside an embossed graphic layer that covers a key of the keyboard. Such a keyboard has a significant user interface value. For example, the embossed key provides the tactile effect of the presence of a key with edges, while allowing for the localized control of haptic vibrations. For such applications, an EMP transducer provides high strains, vibrations or both under control of an electric field. Furthermore, the EMP transducer can generate strong vibrations. When the frequency of the vibrations falls within the acoustic range, the EMP transducer can generate audible sound, thereby functioning as an audio speaker.

Abstract: The present disclosure generally relates to work block encroachment warning systems for providing protection for rail workers working in a mobile or fixed work block. For example, a vehicle (V)-aware unit installed on a moving rail vehicle and a work block limit encroachment unit mounted on a railroad may wirelessly communicate with each other to determine a distance between them. When a vehicle is moving toward an occupied work block, the distance may be used to identify potential hazards.

Abstract: A phototherapy or BRT process and apparatus is provided, which, using a pre-recorded bioresonance frequency or compilation of frequencies, causes an EMR emitter to emit within a biological window of a target organism to positively or negatively affect the organism. The EMR may be generated in one or more LEDs by a device connected to a controller of the EMR emitter which device provides the pre-recorded bioresonance frequency or compilation of frequencies to control the LEDs' emitted light in terms of its intensity and/or a frequency or flicker-rate.

Abstract: Methods, apparatuses, systems, and storage media to track engine components are disclosed. An example apparatus includes a memory; instructions in the apparatus; and processor circuitry to in response to a notification that an engine is undergoing maintenance or in operation, identify an entry in a database that corresponds to the engine, the engine including a module; update historical data corresponding to the module based on the notification; and determine whether the module of the engine has been replaced by extracting data from a data packet obtained via a wireless communication; and when the module of the engine has not been replaced, replace a first identifier of the module stored in the entry with a second identifier of the module and maintain the historical data for the module in the entry.

Abstract: A method of communicating between nodes in a network where a node receives a sequence of symbols that will form a packet on a first communications channel and has a planned packet that it would send on a second communications channel. A destination is encoded into an arbitration portion of a header sequence of the packet, the header sequence comprising a sequence of symbols. The transmission on the second communications channel is as per the planned packet, for as long as the symbols of the planned packet match the symbols being received on the first channel. An arbitration decision is made when the symbols do not match, with the node either continuing to send the rest of the planned packet, or the rest of the packet being received on the first communications channel.

Abstract: A high resolution elastomeric exterior laminate material includes an exterior polymeric film layer laminated to an ink graphic fabric layer. A method of making the high resolution elastomeric exterior laminate material includes providing an ink graphic fabric layer, providing an exterior polymeric film onto a first side of the an ink graphic fabric layer by one of a laminating, a molding, a rolling and an extrusion process to form a laminate.

Abstract: A system for conditioning and moving a fluid can include a thermoelectric device comprising a first side and a second side, the first side configured to heat or cool the fluid with electrical current applied to the thermoelectric device. The system can include a fluid conduit configured to allow a fluid to flow therein and to transfer the fluid into being in thermal communication with the thermoelectric device. The system can include a flow control device in fluid communication with the thermoelectric device, the flow control device configured to direct the fluid in the fluid conduit with respect to the thermoelectric device. The system can include a flapper valve configured to move relative to the thermoelectric device to at least partially block flow of the fluid through a portion of the fluid conduit.

Abstract: Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3? or C4? modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.

Abstract: The Cascaded Wind Turbine is a new concept of wind turbine design featuring multiple hubs in succession, each hub segment adds another tier that create a cascading blade configuration. Each blade set is connected to a separate rotor via a telescopic shaft.

Abstract: Vape devices and methods of operating the same to prevent unauthorized use, allow for remote, centralized storage of operational settings associated with unique payload identifiers, and to optimize operation based on historical usage data, real-time operating conditions, and/or user information. Vape devices for vaporizing dry material and methods of operating the same. Tablets comprising dry material for vaporization and methods of making and using the same. Vape devices and cartridges to improve flow of a fluid payload to an atomizer and to prevent leaking and spurting of the fluid payload, including vape devices and cartridges that pressurize the fluid payload. Vapor measurement systems to determine dosage based on a measured capacitance of vaporized payload. A two-lead communication system that enables the communication of a plurality of electrical signals between a control assembly and cartridge. A cartridge temperature control system that provides localized temperature control for the cartridge.

Abstract: A support device provides elevation and support for a patient's foot, including ankle and heal, and limits lateral and medial rotation of the foot. This protects the knee from injury while healing. The device includes a generally flat main body, two spaced-apart lateral ridges, and a medial depression between the lateral ridges that provides a support surface on which the foot may be positioned. The lateral ridges can extend to a height above the support surface so that inner side surfaces of the lateral ridges are adjacent to a majority of a foot placed in the medial depression. The lateral ridges can terminate below a top of the foot to permit unrestricted ventilation and access to the foot. The lateral ridges can be spaced apart to facilitate placement of a foot onto and removal of the foot from the support surface without manual manipulation of the device.

Abstract: Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3? or C4? modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.

Abstract: This invention is an auxiliary wind turbine featuring an aperture. In the preferred embodiment, the device itself is stationary, and mounts onto host objects that move such as wind turbine blades or vehicles. The Aperture Turbine may be oriented on the host object in a plurality of locations to enhance and maximize the intake of kinetic energy from the air moving around and through the Aperture Turbine when in use.

Abstract: Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3? or C4? modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.

Abstract: A pill splitter that cuts circular pills into four quarters and prevents a user from having to split a single pill, rotate the split pill, and split the pill again in order to obtain a fourth of a dose. The four-way pill splitter is composed of an upper and lower housing. The upper housing contains blades that meet at a vertex and the lower housing contains an inverted cone-shaped insert that the blades from the upper housing fit into so that the vertexes of the blades and the inverted cone-shaped insert only touch in the closed position.