Abstract: This invention is an auxiliary wind turbine featuring an aperture. In the preferred embodiment, the device itself is stationary, and mounts onto host objects that move such as wind turbine blades or vehicles. The Aperture Turbine may be oriented on the host object in a plurality of locations to enhance and maximize the intake of kinetic energy from the air moving around and through the Aperture Turbine when in use.

Abstract: Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3? or C4? modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.

Abstract: A pill splitter that cuts circular pills into four quarters and prevents a user from having to split a single pill, rotate the split pill, and split the pill again in order to obtain a fourth of a dose. The four-way pill splitter is composed of an upper and lower housing. The upper housing contains blades that meet at a vertex and the lower housing contains an inverted cone-shaped insert that the blades from the upper housing fit into so that the vertexes of the blades and the inverted cone-shaped insert only touch in the closed position.

Abstract: The present disclosure generally relates to work block encroachment warning systems for providing protection for rail workers working in a mobile or fixed work block. For example, a vehicle (V)-aware unit installed on a moving rail vehicle and a work block limit encroachment unit mounted on a railroad may wirelessly communicate with each other to determine a distance between them. When a vehicle is moving toward an occupied work block, the distance may be used to identify potential hazards.

Abstract: A hand truck that is reconfigurable between one or more hand truck operational configurations and a hand truck stowed configuration is provided. The hand truck comprises a primary wheel assembly that is aligned in a primary wheel operational configuration in the multiple hand truck operational configurations and a primary wheel stowed configuration in the hand truck stowed configuration.

Abstract: The present invention is directed to a vape device configured to determine the dose of a payload delivered to a user during each of a plurality of user inhalations. In a first embodiment, the vape device tracks the energy used to vaporize a portion of the payload during user inhalation to determine the dose. In a second embodiment, the vape device measures the temperature at multiple locations within the air flow chamber during user inhalation to determine the dose. In a third embodiment, the vape device measures the intensity of light that is transmitted through the vaporized payload, reflected off the vaporized payload, or transmitted through a light transmitting medium positioned within the vaporized payload, during user inhalation to determine the dose.

Abstract: The present disclosure generally relates to work block encroachment warning systems for providing protection for rail workers working in a mobile or fixed work block. For example, a vehicle (V)-aware unit installed on a moving rail vehicle and a work block limit encroachment unit mounted on a railroad may wirelessly communicate with each other to determine a distance between them. When a vehicle is moving toward an occupied work block, the distance may be used to identify potential hazards.

Abstract: Electromechanical polymer (EMP) actuators are used to create haptic effects on a user interface deface, such as a keyboard. The keys of the keyboard may be embossed in a top layer to provide better key definition and to house the EMP actuator. Specifically, an EMP actuator is housed inside an embossed graphic layer that covers a key of the keyboard. Such a keyboard has a significant user interface value. For example, the embossed key provides the tactile effect of the presence of a key with edges, while allowing for the localized control of haptic vibrations. For such applications, an EMP transducer provides high strains, vibrations or both under control of an electric field. Furthermore, the EMP transducer can generate strong vibrations. When the frequency of the vibrations falls within the acoustic range, the EMP transducer can generate audible sound, thereby functioning as an audio speaker.

Abstract: Acoustic absorbers are formed for ultrasound transducers. The acoustic absorber provides desired attenuation, impedance, and thermal conductivity qualities based on a filler of rubber, ceramic, and metal particles. The relative amounts of the different fillers may be adjusted to tune the acoustic attenuation, thermal conductivity, and/or acoustic impedance.

Abstract: The present invention is directed to a system for tracking and reducing consumption of a substance by a user. The system comprises a vape device comprising a payload reservoir configured to contain a payload to be vaporized, wherein the payload includes the substance, and an atomizer configured to vaporize a portion of the payload during each of a plurality of user inhalations. The system also comprises a software application executable on the computing device, wherein the software application causes the computing device to determine a dosage schedule that causes a reduction in consumption of the substance over a period of time, and control operation of the vape device in accordance with the dosage schedule during a substance reduction period.

Abstract: A cattle curtain utilizing a wicking action to displace concentrated insecticide to be wiped on animals as they pass through an animal pathway. The cattle curtain includes a reservoir body for holding the concentrated insecticide. A series of ropes is secured within the reservoir body, and the series of ropes is secured through fittings, whereby a metal pin is inserted through each rope. A valve disposed on top of the reservoir body to control flow of the concentrated insecticide into the series of ropes.

Abstract: The Cascaded Wind Turbine is a new concept of wind turbine design featuring multiple hubs in succession, each hub segment adds another tier that create a cascading blade configuration. Each blade set is connected to a separate rotor via a telescopic shaft.

Abstract: A support device provides elevation and support for a patient's foot, including ankle and heal, and limits lateral and medial rotation of the foot. This protects the knee from injury while healing. The device includes a generally flat main body, two spaced-apart lateral ridges, and a medial depression between the lateral ridges that provides a support surface on which the foot may be positioned. The lateral ridges can extend to a height above the support surface so that inner side surfaces of the lateral ridges are adjacent to a majority of a foot placed in the medial depression. The lateral ridges can terminate below a top of the foot to permit unrestricted ventilation and access to the foot. The lateral ridges can be spaced apart to facilitate placement of a foot onto and removal of the foot from the support surface without manual manipulation of the device.

Abstract: In certain embodiments, a battery thermal management system includes at least one battery, at least one thermoelectric device in thermal communication with the at least one battery, and a conduit comprising an inlet configured to allow a working fluid to enter and flow into the conduit and into thermal communication with the at least one thermoelectric device. The conduit further comprises an outlet configured to allow the working fluid to exit and flow from the conduit and away from being in thermal communication with the at least one thermoelectric device. The battery thermal management system can further include a first flow control device which directs the working fluid through the inlet of the conduit and a second flow control device which directs the working fluid through the outlet of the conduit. The first flow control device and the second flow control device are each separately operable from one another.

Abstract: Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3? or C4? modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.

Abstract: Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3? or C4? modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.

Abstract: Provided are certain derivatives of amphotericin B (AmB) characterized by reduced toxicity and retained anti-fungal activity. Certain of the derivatives are C16 urea derivatives of AmB. Certain of the derivatives are C3, C5, C8, C9, C11, C13, or C15 deoxy derivatives of AmB. Certain of the derivatives include C3? or C4? modifications of the mycosamine appendage of AmB. Also provided are methods of making AmB derivatives of the invention, pharmaceutical compositions comprising AmB derivatives of the invention, and methods of use of AmB derivatives of the invention.

Abstract: The invention relates to the field of data packet management, and more specifically to the field of managing of data packets in such a manner that power consumption is reduced, such reduction being especially beneficial for portable device applications. In accordance with an embodiment of the invention there is provided a method of handling and manipulating data wherein padding and unpadding operations for a packet of data are performed at the transmission/reception of a packet from a network, and data handling is minimized within the portable device. According to another embodiment of the invention there is provided a method of encryption for packet data absent the padding data.

Abstract: A rail worker protection system having a first device configured to generate and send an identification code, a second device configured to transmit a request to the first device and to transmit a signal to one or more remote devices, and the remote device able to issue alarms to rail workers upon reception of the signal from the second device.

Abstract: Electromechanical polymer (EMP) actuators are used to create haptic effects on a user interface deface, such as a keyboard. The keys of the keyboard may be embossed in a top layer to provide better key definition and to house the EMP actuator. Specifically, an EMP actuator is housed inside an embossed graphic layer that covers a key of the keyboard. Such a keyboard has a significant user interface value. For example, the embossed key provides the tactile effect of the presence of a key with edges, while allowing for the localized control of haptic vibrations. For such applications, an EMP transducer provides high strains, vibrations or both under control of an electric field. Furthermore, the EMP transducer can generate strong vibrations. When the frequency of the vibrations falls within the acoustic range, the EMP transducer can generate audible sound, thereby functioning as an audio speaker.