Abstract: An electro-mechanical box trainer for neurosurgery comprise: (i) a base part which comprises a rubberized working port (11) for insertion of endoscope (26) and tool (25) for manipulation, a microcontroller programmed motorized peg plate (14) placed at 45° degrees of inclination for defining a practice volume according to the neuroendoscopy, a membrane keypad to change the angle of rotation of said peg plate (14) along vertical axis, liquid crystal display (LED) array to illuminate the interior of the box and a removable base plate (6) to house the circuitry; and (ii) a removable part enclosed of five walls such as a front wall (18), two lateral walls (17 and 19), a back wall (20) and a top wall (23), comprises a housing to mount an auxiliary camera (32) to record all the task for evaluation and a slider at the back to adjust the camera focus.

Abstract: The present invention includes a method for identifying an Alzheimer's disease (AD) patient prior to reaching clinical disease classification, comprising: obtaining a dataset associated with a blood, serum, or plasma sample from the patient, wherein the dataset comprises data representing the level of one or more microRNA biomarkers in the blood, serum, or plasma sample; assessing the dataset for a presence or an increase in an amount of miRNA-455-3p; determining the likelihood that the patient will develop AD patient prior to reaching clinical disease classification by detecting the presence or the increase in miRNA-455-3p to produce a score that is indicative of a likelihood of developing AD, wherein a higher score relative to a healthy control indicates that the patient is likely to have the prognosis for transitioning to classified AD, wherein the healthy control is derived from a non-AD patient with no clinical evidence of AD.

Abstract: The present invention includes a method of protecting neuronal cells from A?-induced toxicities in a subject comprising: providing the subject in need of treatment for an A?-induced toxicity with an agent that increases the miRNA-445-3p in the subject, wherein an increase in miR-455-3p expression in the neuronal cells enhances neuronal cell survival.

Abstract: The present invention includes a method of protecting neuronal cells from A?-induced toxicities in a subject comprising: providing the subject in need of treatment for an A?-induced toxicity with an agent that increases the miRNA-445-3p in the subject, wherein an increase in miR-455-3p expression in the neuronal cells enhances neuronal cell survival.

Abstract: Embodiments herein describe a reconfigurable integrated circuit (IC) where data can be retained in memory when performing a partial reconfiguration. Partial reconfiguration includes reconfiguring programmable logic in the IC while certain functions of the IC remain operational or active. In one embodiment, the reconfigurable IC includes control logic for saving or retaining data in the IC during a partial reconfiguration. That is, rather than clearing the memory elements, the user can specify that the memory blocks containing certain data should be retained while the other memory blocks can be cleared. In this manner, the data can be retained in the IC during a partial reconfiguration which saves time, power, and cost. Once partial reconfiguration is complete, the newly configured programmable logic can retrieve and process the saved data from the on-chip memory.

Abstract: Systems and methods are disclosed for managing workload among server clusters is disclosed. According to certain embodiments, the system may include a memory storing instructions and a processor. The processor may be configured to execute the instructions to determine historical behaviors of the server clusters in processing a workload. The processor may also be configured to execute the instructions to construct cost models for the server clusters based at least in part on the historical behaviors. The cost model is configured to predict a processor utilization demand of a workload. The processor may further be configured to execute the instructions to receive a workload and determine efficiencies of processing the workload by the server clusters based at least in part on at least one of the cost models or an execution plan of the workload.

Abstract: To reduce the bulk of the acquisition systems embedded onboard an aircraft and dedicated to predicting failures, an acquisition system is provided comprising an avionics rack and at least one recording device, in which the avionics rack comprises a front panel provided with at least one test connector configured to be connected to all or some of the data buses of the aircraft, each recording device comprises a housing and an acquisition port, the acquisition port being provided on an outer face of the housing, the acquisition port of each recording device is engaged with a corresponding test connector of the avionics rack, each recording device is configured to acquire at least some signals applied to the acquisition port by the corresponding test connector, and to store the acquired signals.

Abstract: A non-transitory storage medium stores an assembled genetic sequence comprising aligned sequencing reads. An electronic processing device is configured to perform operations including: identifying a possible variant in the assembled genetic sequence; computing value of at least one read property for reads of the assembled genetic sequence; and calling the possible variant conditional upon the computed values of the at least one read property for sequencing reads of the assembled genetic sequence that include the possible variant satisfying an acceptance criterion. The electronic processing device may be further configured to select at least one region of the assembled genetic sequence for validation based on a non random selection criterion.

Abstract: A system for directing a shopper to an item of interest in a store comprises a floor surface at a store configured with indicators that communicate with each other to identify a path for guiding a store visitor from a current location to a location of an item of interest; a mobile device application executed by a mobile electronic device, the mobile device application generating a request for locating the item of interest; and a special-purpose processor that calculates the path from the current location of the store visitor to the location of the item of interest in response to the request received from the mobile device application. The indicators identify the path in response to the special-purpose processor calculating the path.

Abstract: Systems and methods are disclosed for managing workload among server clusters is disclosed. According to certain embodiments, the system may include a memory storing instructions and a processor. The processor may be configured to execute the instructions to determine historical behaviors of the server clusters in processing a workload. The processor may also be configured to execute the instructions to construct cost models for the server clusters based at least in part on the historical behaviors. The cost model is configured to predict a processor utilization demand of a workload. The processor may further be configured to execute the instructions to receive a workload and determine efficiencies of processing the workload by the server clusters based at least in part on at least one of the cost models or an execution plan of the workload.

Abstract: A pinning service interaction agent receives a user input indicating an object, corresponding to an application, to be pinned to a selected mobile device screen. The agent receives user selection of content, that is stored in a document on a remote data store, to be displayed in the object. The agent intermittently receives refresh data refreshing the content displayed in the pinned object based on the content stored in the document on the remote data store.

Abstract: Certain disclosed embodiments provide improved systems and methods for processing jobs. The method comprises steps including receiving, from a client device over a network, information representing a job and generating at least two tasks representative of the job. The method further comprises, for each task, assigning, by a processor, a signature to the task representative of whether the task has been processed, determining at least one dataset related to the task, and assigning a signature to the determined at least one dataset. The method further comprises searching, by the processor, a data structure for the task signature, and based on the searching, sending the task over a network to a task executor for processing or locating results associated with the task. The method further comprises sending, over a network, a job result to the client device. Systems and computer-readable media are also provided.

Abstract: A method for generating an environmental profile is provided. The method for generating environmental profile includes generating an image of an environment by capturing the environment with at least one recording device, detecting a change of an object in the environment based on the image, and generating an environmental profile based on the change of the object.

Abstract: A compressor system includes a compression module having an inlet for receiving air; and a filter housing in fluid communication with the compression module. The filter housing is constructed to house a filter, the filter having a sealing feature disposed at a first end of the filter and having an engagement feature disposed at a second end of the filter opposite the first end. The filter housing includes a trap door constructed to contact the engagement feature, and constructed to drive the engagement feature in a direction parallel to an axis of the filter toward the sealing feature and urge the sealing feature into sealing engagement with the filter housing.

Abstract: Systems and methods are disclosed for managing workload among server clusters is disclosed. According to certain embodiments, the system may include a memory storing instructions and a processor. The processor may be configured to execute the instructions to determine historical behaviors of the server clusters in processing a workload. The processor may also be configured to execute the instructions to construct cost models for the server clusters based at least in part on the historical behaviors. The cost model is configured to predict a processor utilization demand of a workload. The processor may further be configured to execute the instructions to receive a workload and determine efficiencies of processing the workload by the server clusters based at least in part on at least one of the cost models or an execution plan of the workload.

Abstract: Certain disclosed embodiments provide improved systems and methods for processing jobs. The method comprises steps including receiving, from a client device over a network, information representing a job and generating at least two tasks representative of the job. The method further comprises, for each task, assigning, by a processor, a signature to the task representative of whether the task has been processed, determining at least one dataset related to the task, and assigning a signature to the determined at least one dataset. The method further comprises searching, by the processor, a data structure for the task signature, and based on the searching, sending the task over a network to a task executor for processing or locating results associated with the task. The method further comprises sending, over a network, a job result to the client device. Systems and computer-readable media are also provided.

Abstract: Methods and apparatus are described for converting a pre-silicon Open Verification Methodology or Universal Verification Methodology (OVM/UVM) device under test (DUT) into a design implementable on a programmable integrated circuit (IC) and for converting the pre-silicon OVM/UVM stimulus from the driver and expected response from the scoreboard into timing aware stimulus-response vectors that can be applied through the tester onto the pads of the programmable IC that contains the implemented design. This approach can handle the clock and other input stimuli changing concurrently in the pre-silicon testbench, and the vectors generated therefrom will be in the proper form so as to work deterministically on the silicon on the tester.

Abstract: The present disclosure relates to aluminum based alloys and a method for producing the aluminum based alloys. The method comprises acts of, casting of the aluminum based alloy in a chilled casting mold. Then, aging the cast aluminum based alloy at a first predetermined temperature for a first predetermined time. The aging results in the formation of a first precipitate. Followed by this, solutionizing the aluminum based alloy at a second predetermined temperature for a second predetermined time such that the major alloying element is dissolved in aluminum matrix without much affecting the first precipitate. Then, aging the aluminum based alloy at a third predetermined temperature for a third predetermined time. The aging results in the formation of a second precipitate.

Abstract: A thermal valve unit is provided for use with an oil filled screw compressor. The thermal valve unit can be affixed to an exterior pipe segment and can include a thermally responsive element in thermal communication with compressed air traversing through the pipe segment. The valve unit can include a movable valve member actuated by the thermally responsive element that opens and closes oil passages to selectively route oil either to a heat exchanger prior to being delivered to the oil filled compressor, or directly to the compressor without passing through the heat exchanger.

Abstract: In an example, a memory circuit in a programmable integrated circuit (IC) includes: a control port and a clock port; a configurable random access memory (RAM) having a control input and a clock input; input multiplexer logic coupled to the control input and the clock input; and a state machine coupled to the input multiplexer logic and configuration logic of the programmable IC, the state machine configured to: in response to being enabled by the configuration logic, control the input multiplexer logic to switch a connection of the control input from the control port to the state machine and, subsequently, switch a connection of the clock input from the clock port to a configuration clock source; and in response to being disabled by the configuration logic, control the input multiplexer logic to switch the connection of the clock input from the configuration clock source to the clock port and, subsequently, switch the connection of the control input from the state machine to the control port.