Abstract: This invention features betulinic acid derivatives having the formula: wherein the variables are defined herein. The invention also provides related compounds and intermediates thereof, as well as pharmaceutical compositions, kits, and articles of manufacture comprising such compounds. Treatment methods and methods of manufacture are also provided.

Abstract: In a copying operation, an MFP reads a code image printed on the paper, acquires a paper ID from the code image, acquires paper information associated with the paper ID, specifies an electronic document as a print source, and acquires the specified electronic document. The MFP prints a paper ID on the paper with the code image and the acquired electronic document, and stores paper information including a paper ID of a copy source in association with the paper ID. When a first MFP leaves an image processing system, respective information concerning electronic document acquisition managed by the first MFP is transferred to a second MFP.

Abstract: The present invention concerns methods for treating and preventing renal/kidney disease, insulin resistance/diabetes, fatty liver disease, and/or endothelial dysfunction/cardiovascular disease using synthetic triterpenoids, optionally in combination with a second treatment or prophylaxis.

Abstract: In printing an electronic document on a paper, an MFP prints a code image created by encoding a paper ID including a local ID issued to the paper and stores paper information with the paper ID. The MFP determines a type of data format, creates a paper ID in the data format, and prints a code image created by encoding the paper ID. In copying a printed paper, the MFP decodes the code image printed on the paper to acquire the paper ID and retrieves paper information associated with the paper ID according to the data format. The MFP specifies the electronic document as a print source from retrieved paper information and performs printing using the electronic document.

Abstract: This invention describes novel tricyclic-bis-enone derivatives (TBEs), such as TBE-31, TBE-34, TBE-45 and water-soluble TBEs. The methods of preparing these compounds are also disclosed. The inventors demonstrate the ability of these new TBEs to inhibit proliferation of human myeloma cells, inhibit the induction of iNOS in cells stimulated with interferon-?, induce heme oxygenase-1 (HO-1), induce CD11b expression—a leukemia differentiation marker, inhibit proliferation of leukemia cells, induce apoptosis in human lung cancer, and induce apoptosis in other cancerous cells. The TBEs of this invention are expected to be useful agents for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.

Abstract: Novel tricyclic-bis-enone derivatives (TBEs) as well as the process for the preparation of such TBEs are provided. Also provided are methods for prevention and/or treatment of cancer, Alzheimer's disease, Parkinson's disease, multiple sclerosis, amyotropic lateral sclerosis, rheumatoid arthritis, inflammatory bowel disease, and all other diseases whose pathogenesis is believed to involve excessive production of either nitric oxide (NO) or prostaglandins or the overexpression of iNOS or COX-2 genes or gene products. Further, methods for the synthesis of the TBE compounds of the invention utilize cheap commercially available reagents and are highly cost effective and amenable to scale-up. Additional high efficiency synthetic methods that utilize novel intermediates as well as the synthesis of these intermediates are also provided. Furthermore, the invention also provides methods for designing novel and water-soluble TBEs.

Abstract: The present invention relates providing a magnetic data eraser that is capable of performing magnetizing process for magnetizing magnetic recording medium such as a hard disk drive (HDD) is easily and with reduced electric power. The magnetic data eraser includes: holding drawer means for holding a magnetic recording medium which means has a mounting tray for mounting the magnetic recording medium, wherein the mounting tray is inclined a predetermined value of degrees of angle; and magnetizing means for magnetizing the magnetic recording medium, wherein the magnetizing means is covered by a magnetizing coil and has a hollow body portion, the holding drawer means being accommodated in the hollow body portion, and the magnetic recording medium being placed on the mounting tray of the holding drawer means.

Abstract: Compounds and methods useful for chemopreventative treatment of diseases such as cancer, Alzheimer's disease, Parkinson's disease, inflammatory bowel diseases, and multiple sclerosis.

Abstract: The present invention features monocyclic cyanoenone compositions and methods for using the same in the treatment of diseases such as cancer, inflammatory diseases and neurodegenerative diseases.

Abstract: This invention describes novel tricyclic-bis-enone derivatives (TBEs), such as TBE-31, TBE-34, TBE-45 and water-soluble TBEs. The methods of preparing these compounds are also disclosed. The inventors demonstrate the ability of these new TBEs to inhibit proliferation of human myeloma cells, inhibit the induction of iNOS in cells stimulated with interferon-?, induce heme oxygenase-1 (HO-1), induce CD11b expression—a leukemia differentiation marker, inhibit proliferation of leukemia cells, induce apoptosis in human lung cancer, and induce apoptosis in other cancerous cells. The TBEs of this invention are expected to be useful agents for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.

Abstract: Compounds and methods useful for chemopreventative treatment of diseases such as cancer, Alzheimer's disease, Parkinson's disease, inflammatory bowel diseases, and multiple sclerosis.

Abstract: Novel tricyclic-bis-enone derivatives (TBEs) as well as the process for the preparation of such TBEs are provided. Also provided are methods for prevention and/or treatment of cancer, Alzheimer's disease, Parkinson's disease, multiple sclerosis, amyotropic lateral sclerosis, rheumatoid arthritis, inflammatory bowel disease, and all other diseases whose pathogenesis is believed to involve excessive production of either nitric oxide (NO) or prostaglandins or the overexpression of iNOS or COX-2 genes or gene products. Further, methods for the synthesis of the TBE compounds of the invention utilize cheap commercially available reagents and are highly cost effective and amenable to scale-up. Additional high efficiency synthetic methods that utilize novel intermediates as well as the synthesis of these intermediates are also provided. Furthermore, the invention also provides methods for designing novel and water-soluble TBEs.

Abstract: To accurately regulate output of a high-frequency power with a simple configuration. A high-frequency power supply circuit includes: a basic drive square wave generation circuit unit (5) for generating a basic drive square wave having an output frequency; a differential signal generation circuit unit (9) for generating a front edge differential signal of the basic drive square wave; a vibrator circuit unit (15) having a square wave signal generator (10) for outputting a square wave signal having a signal width within a period corresponding to a half cycle of the output frequency upon input of a trigger signal from outside and signal width control circuits (11, 12) varying/controlling the signal width of the square wave signal according to the control signal; and a switching amplification circuit unit (6) for amplifying the amplification source signal based on the output signal from the vibrator circuit unit (15).

Abstract: This invention describes novel tricyclic-bis-enone derivatives (TBEs), such as TBE-31, TBE-34, TBE-45 and water-soluble TBEs. The methods of preparing these compounds are also disclosed. The inventors demonstrate the ability of these new TBEs to inhibit proliferation of human myeloma cells, inhibit the induction of iNOS in cells stimulated with interferon-?, induce heme oxygenase-1 (HO-1), induce CD11b expression—a leukemia differentiation marker, inhibit proliferation of leukemia cells, induce apoptosis in human lung cancer, and induce apoptosis in other cancerous cells. The TBEs of this invention are expected to be useful agents for the treatment and prevention of many diseases, including cancer, neurological disorders, inflammation, and pathologies involving oxidative stress.

Abstract: Novel tricyclic-bis-enone derivatives (TBEs) as well as the process for the preparation of such TBEs are provided. Also provided are methods for prevention and/or treatment of cancer, Alzheimer's disease, Parkinson's disease, multiple sclerosis, amyotropic lateral sclerosis, rheumatoid arthritis, inflammatory bowel disease, and all other diseases whose pathogenesis is believed to involve excessive production of either nitric oxide (NO) or prostaglandins or the overexpression of iNOS or COX-2 genes or gene products. Further, methods for the synthesis of the TBE compounds of the invention utilize cheap commercially available reagents and are highly cost effective and amenable to scale-up. Additional high efficiency synthetic methods that utilize novel intermediates as well as the synthesis of these intermediates are also provided. Furthermore, the invention also provides methods for designing novel and water-soluble TBEs.

Abstract: The present invention concerns methods for treating and preventing renal/kidney disease, insulin resistance/diabetes, fatty liver disease, and/or endothelial dysfunction/cardiovascular disease using synthetic triterpenoids, optionally in combination with a second treatment or prophylaxis.

Abstract: A system and apparatus are provided for managing cables, wires, and cords, and more particularly, to organize and route cables and wires in various directions. For example, there is provided an apparatus comprising: a cable clip with a rigid circular base and a flexible dome-shaped head, wherein the base includes a central aperture and an adhesive layer covered by a protective film on one side and is integrated with the dome-shaped head on the other side. The dome-shaped head has a plurality of slots that extend radially across the head and intersect with one another, forming an opening. In one embodiment, each slot has circular shaped arcuate openings on opposites sides creating first and second transit paths for a cable or wire. The resulting dome-shaped head has a plurality of retaining arms that receive cables, retains them, and can be attached to a surface by a variety of methods.

Abstract: As receiving information for specifying a dwell unit and a request of creating an inspection list, a dwell unit information server creates an inspection list for the dwell unit in response to the request. A multiple function processing machine prints out the inspection list, and reads the inspection list on which a defective equipment is written. The multiple function processing machine extracts handwritten information from read-out information, and transmits the extracted information to the dwell unit information server together with code information printed on the inspection list. The dwell unit information server extracts an equipment needing inspection based on the code information and the handwritten information, and transmits a work instruction which instructs maintenance/repair of the equipment to a maintenance/repair responsible company responsible for the extracted equipment.

Abstract: [Problems] To accurately regulate output of a high-frequency power with a simple configuration. [Means for Solving Problems] A high-frequency power supply circuit includes: a basic drive square wave generation circuit unit (5) for generating a basic drive square wave having an output frequency; a differential signal generation circuit unit (9) for generating a front edge differential signal of the basic drive square wave; a vibrator circuit unit (15) having a square wave signal generator (10) for outputting a square wave signal having a signal width within a period corresponding to a half cycle of the output frequency upon input of a trigger signal from outside and signal width control circuits (11, 12) varying/controlling the signal width of the square wave signal according to the control signal; and a switching amplification circuit unit (6) for amplifying the amplification source signal based on the output signal from the vibrator circuit unit (15).