Abstract: A method for dry detection/quantification of targeted nucleotide chains, comprising the steps of: (1) realizing a state in which a hybrid (C) of a certain amount of targeted nucleotide chain (A), which is derived from a sample solution and subjected to detection or quantification, and a probe nucleotide chain (B), which has a base sequence complementary to a specific site of the base sequence of the targeted nucleotide chain, is formed on a solid-phase substrate by mutually reacting the two types of nucleotide chains with each other, and in which there exists a fluorescence dye (D), which acts on the hybrid (C), thereby emits fluorescence or increases its fluorescence intensity, and is capable of continuing to emit fluorescence even in the dried state while acting on the hybrid; (2) drying the hybrid (C) and the fluorescence dye (D) on the substrate; and (3) measuring the fluorescence emitted from the fluorescence dye (D), as a measuring means, after the drying operation.

Abstract: To provide a technology for obtaining a probe carrier which is quality assured by an effective inspection program and an effective producing steps. Quality of a produced probe carrier is ensured by expanding test items in the processes from synthesis and purification of the probe to fixation thereof to a carrier.

Abstract: A method for screening presence or absence of a variation in a region of a nucleic acid which comprises the steps of (a) preparing a sample containing a test nucleic acid corresponding to the region, (b) preparing a probe having a base sequence fully complementary to a normal sequence of the region, and a plurality of probes each having at least one base not complementary to the normal sequence, (c) fixing the probes in separate regions on a surface of a substrate to prepare a DNA array substrate, (d) reacting the test nucleic acid with the probes on the DNA array substrate, (e) measuring signals in each region where the signals are originated from respective hybrids formed between the test nucleic acid and one of the probes, and (f) calling variation in the test nucleic acid using a pattern of total signals of all regions.

Abstract: A method for screening presence or absence of a variation in a region of a nucleic acid which comprises the steps of (a) preparing a sample containing a test nucleic acid corresponding to the region, (b) preparing a probe having a base sequence fully complementary to a normal sequence of the region, and a plurality of probes each having at least one base not complementary to the normal sequence, (c) fixing the probes in separate regions on a surface of a substrate to prepare a DNA array substrate, (d) reacting the test nucleic acid with the probes on the DNA array substrate, (e) measuring signals in each region where the signals are originated from respective hybrids formed between the test nucleic acid and one of the probes, and (f) calling variation in the test nucleic acid using a pattern of total signals of all regions.

Abstract: A carrier having indexes in a probe non-fixing region is used and solutions containing probes are applied to respective specific positions on the carrier by referring to said indexes and fixed. The position of a target compound that is specifically bonded to a probe fixed to a probe carrier manufactured by a method according to the invention can be accurately and quickly detected by referring to the indexes.

Abstract: A carrier having indexes in a probe non-fixing region is used and solutions containing probes are applied to respective specific positions on the carrier by referring to said indexes and fixed. The position of a target compound that is specifically bonded to a probe fixed to a probe carrier manufactured by a method according to the invention can be accurately and quickly detected by referring to the indexes.

Abstract: An optometric apparatus 2 according to the present invention comprises a body portion 5r provided with an optical system for a right eye for projecting a chart for the right eye in order to inspect visual function of both eye of an examinee and a body portion 5l provided with an optical system for a left eye for projecting a chart for the left eye, the optical systems for the right and left eyes projecting the same fusion patterns to perform fusion of the both eyes of the examinee.

Abstract: An organic light-emitting device (OLED) in which pyrylium salt or its derivative, such as thiapyrylium, selenapyrylium, or telluropyrylium, is used as a charge transport material and/or at least a dopant or principal component in a charge transport layers.

Abstract: The analysis method according to the present invention provides a method for detecting the target nucleic acid in the sample, in which the problems caused by employing the radio isotope and fluorescent methods can be solved, thereby enabling the acquisition of gene information with higher accuracy. A method for analyzing a target nucleic acid in a sample is conducted by: reacting the sample with a probe support having two or more probes fixed thereon, which contain a base portion being complementary with a base sequence of the target nucleic acid; and detecting an existence of a hybridized complex of the probe and the target nucleic acid using time of flight secondary ion mass spectrometry, in which the hybridized complex is formed when the target nucleic acid is contained in the sample, wherein the target nucleic acid and the nucleic acid probe are a combination of RNA and DNA.

Abstract: An organic light-emitting device (OLED) in which pyrylium salt or its derivative, such as thiapyrylium, selenapyrylium, or telluropyrylium, is used as a charge transport material and/or at least a dopant or principal component in a charge transport layers.

Abstract: Nucleic acid probes arranged on a nucleic acid chip substrate in a matrix form can be analyzed quantitatively by TOF-SIMS with accuracy by forming a phosphorus-containing area which can be used as a standard on the substrate.

Abstract: A method of analyzing a measuring sample is provided which is capable of accurately analyzing the state of a probe disposed on a carrier and formation/unformation of a hybrid between the probe and a target nucleic acid, for example, imaging of the disposing locations and quantitative analysis thereof.

Abstract: To provide a DNA micro-array having a nucleic acid probe immobilized on a substrate, which is used to detect a molecule of a target nucleic acid contained in a sample and has a substantially complementary base sequence to the target base sequence of the nucleic acid molecule, including at least one probe selected from the group consisting of: at least one internal standard probe for assay of PCR of the target nucleic acid; at least one external standard probe for a detection operation and assay of an amount of the probe; and a probe for measurement of the amount or density of the nucleic acid probe, formed by the same method as the nucleic acid probe.

Abstract: To provide a method of making measurements for a sample on the measuring surfaces of a substrate which makes it possible to simplify the control and construction of a measuring device, shorten the measuring period, make the measuring conditions constant, and improve the positional accuracy. The method and a device for carrying out the method are characterized in that measurements for the sample is performed by forming a circular orbit of detection areas, where detection is performed with a detector, on the measuring surfaces of the substrate while moving the detection areas relative to the substrate.

Abstract: In an air conditioner (1) constructed to pass an air introduced into an air conditioning unit (4) through an evaporator (33) and a heater core (34) both arranged in the unit (4), cooler pipes (90) for the evaporator (33) and heater pipes (91) for the heater core (34) are arranged to extend from the same side wall of the air conditioning unit (4).

Abstract: In order to observe a front eye portion of an eye (E) to be examined, when a frame is moved to within a first region to approach the eye E to be examined, a stereo angle converting portion as means for shifting an optical path and a color temperature converting element (61) as optical converting means are removed from right and left optical axes (L1 and L2). On the other hand, in order to observe an eye fundus portion of the eye (E) to be examined, when the frame is moved to within a second region to leave the eye (E) to be examined, the stereo angle converting portion and the color temperature converting element (61) are disposed on the right and left optical axes (L1 and L2).

Abstract: A receiver is rapidly and accurately tuning a broadcast frequency and selecting a broadcast program by simple operation and also for clearly informing the user of receivable broadcast frequencies. Besides a number of broadcast programs, information indicating the transmission site position for the broadcast RF, the station name broadcasting that RF, the program name, and information showing whether or not the multiplexed program is a regional program matching a designated region, is also multiplexed on the digital audio broadcast and RF received and demodulated in a receiver section.

Abstract: A probe array comprises a plurality of probes immobilized at a plurality of matrix sites on a substrate for capturing a target substance, wherein the probes are sequentially synthesized at the matrix sites on the substrate until a desired length, the probes are different from each other, and a labeling compound is coupled to each terminus of the probes in a final step of the synthesis. The probe array of the invention allows sensitive and reliable detection of the target substance. A method of evaluating the amount of the fully synthesized probes at respective matrix sites is also provided.

Abstract: Multiple specimens, typically biological samples having different properties and origins, are bound onto matrix substrates, and oligonucleotides, proteins and drugs are spotted on each matrix in an array to examine those specimens at a time for multiple items.

Abstract: Disclosed are a navigation system and/or a point information display method and a program. The navigation system consists mainly of: a stream receiver that receives broadcast streams; a data decoder that samples a data signal from the received streams and decodes the data signal into character string information; a matching block that performs matching to compare a predetermined keyword, which is associated with position information specified in map information data, with stored keywords and searches a keyword consistent with the keyword contained in the character string information; a position information searching block that searches position information associated with the keyword contained in the character string information and detected to be consistent with a stored keyword by the matching block; and a display unit that displays the detected position information while superimposing it on a display image.