Abstract: To provide a method of making measurements for a sample on the measuring surfaces of a substrate which makes it possible to simplify the control and construction of a measuring device, shorten the measuring period, make the measuring conditions constant, and improve the positional accuracy. The method and a device for carrying out the method are characterized in that measurements for the sample is performed by forming a circular orbit of detection areas, where detection is performed with a detector, on the measuring surfaces of the substrate while moving the detection areas relative to the substrate.

Abstract: A probe bound substrate allowing us to quickly detect or quantify a target substance or sequence a target nucleic acid at a lower cost is provided. Specifically, there is provided a probe bound substrate in which a probe capable of specifically attaching to a target substance is bound at the first site on its surface, characterized in that a marker is bound at the second site where the first site may be specified.

Abstract: Multiple specimens, typically biological samples having different properties and origins, are bound onto matrix substrates, and oligonucleotides, proteins and drugs are spotted on each matrix in an array to examine those specimens at a time for multiple items.

Abstract: An apparatus for receiving broadcasting signals includes a signal receiving portion for receiving a broadcasting signal, a frequency convertor for converting the broadcasting signal received by the signal receiving portion, an IF amplifier, an A/D convertor, a digital demodulator, a program selector for selecting one of plural groups of program information data obtained from the digital demodulator, an information reproducing portion for reproducing program information, and an operation controller operative to put at least each of the signal receiving portion, the frequency convertor and the IF amplifier in a reduced power consumption state in periods other than a period in which portions of the broadcasting signal, which carry the synchronous data, the control information data and the program information data to be selected by the program selector, respectively, are able to be received by the signal receiving portion.

Abstract: A reaction site array to be used in conducting a plurality of reactions between two or more kinds of substances in a liquid medium with a trace amount is provided. The reaction site array comprises a plurality of reaction sites separated from each other. Each reaction site is composed of a first region and a second region. The second region is raised from the first region to separate the first regions from each other. The second region has an affinity to a liquid medium lower than that of the first region. A preparation process of the reaction site and a reaction process using the reaction site array is also provided.

Abstract: This invention provides a pattern exposure method which may be used for effectively preparing, for example, a DNA or peptide array with a lower cost and a device therefor. Specifically, the method is a method for pattern exposure comprising the step of exposing a photosensitive material on a solid-phase substrate by irradiating it with a light as a pattern, wherein the photosensitive material is selectively exposed with beams selectively emitted from multiple vertical cavity surface emitting laser sources aligned as an array.

Abstract: A method for identifying an unknown base sequence present in a target single-stranded nucleic acid utilizing a probe array in which single-stranded nucleic acid probes are arranged as isolated spots on a substrate, where each probe has a base sequence complementary to one of plural base sequences expected to be the unknown base sequence, and fluorescence pattern of a sample on the probe array is compared with template patterns to know the base sequence of the sample.

Abstract: A reaction site array to be used in conducting a plurality of reactions between two or more kinds of substances in a liquid medium with a trace amount is provided. The reaction site array comprises a plurality of reaction sites separated each other, each of the reaction sites is composed of a first region and a second region, the second region is raised from the first region to separate the first regions each other, and the first region has an affinity to the liquid medium and the second region has an affinity to the liquid medium lower than that of the first region. A preparation process of the reaction site array and a reaction process using the reaction site array are also provided.

Abstract: An air conditioning unit and an air blowing unit are connected via an intermediate duct. The air conditioning unit includes an air mix damper and a discharge direction switching damper for switching the discharge direction of conditioned air, each driven by a corresponding actuator via a link mechanism associated therewith. The link mechanism and actuator are mounted on a left wall part of a casing of the air conditioning unit. On the other hand, the air blowing unit is provided with an actuator for driving an indoor air/outside air switching damper, and the actuator is mounted to a side of a casing of the air blowing unit facing the air conditioning unit. Thus, the resulting air conditioner is reduced in size to reduce its installation space.

Abstract: Provided is a method of spotting a probe densely and efficiently on a surface of a solid support. A liquid containing a probe is attached to a solid support as droplets to form spots containing the probe on the solid support by an ink jet method.

Abstract: Method of manufacture of probe carriers and an apparatus used for the method in which the product of the Reynolds number and the Weber number, calculated from diameter and speed of a droplet of a probe solution, and density and surface tension of the probe solution, is set in the predetermined range. In accordance with the present invention, there are achieved high uniformity of the area and shape in each probe arranged on the probe carrier, and less tendency to rebound at impact of the probe solution on the substrate. Probe carriers having very uniform area and shape of the probes are obtained, according to the present invention.

Abstract: A probe array comprises a plurality of probes immobilized at a plurality of matrix sites on a substrate for capturing a target substance, wherein the probes are sequentially synthesized at the matrix sites on the substrate until a desired length, the probes are different from each other, and a labeling compound is coupled to each terminus of the probes in a final step of the synthesis. The probe array of the invention allows sensitive and reliable detection of the target substance. A method of evaluating the amount of the fully synthesized probes at respective matrix sites is also provided.

Abstract: A polygon drawing apparatus for drawing a polygon which is colored inside its outline by using outline data indicating the outline of the polygon, the apparatus comprising: an outline data generation unit for generating outline data indicating the outline of the polygon on the basis of coordinate data indicating the coordinates of points constituting the polygon; a mask data generation unit for performing, for a predetermined amount of the outline data, parallel exclusive-OR processes in units of amounts constituting the predetermined amount, thereby generating mask data which specifies “coloring” for the inside of the outline; and a segment generation unit for drawing the polygon by using the mask data generated by the mask data generation means. Therefore, this polygon drawing apparatus can provide a satisfactory result of display without using a bulk memory, and without increasing the processing load.

Abstract: A carrier having indexes in a probe non-fixing region is used and solutions containing probes are applied to respective specific positions on the carrier by referring to said indexes and fixed. The position of a target compound that is specifically bonded to a probe fixed to a probe carrier manufactured by a method according to the invention can be accurately and quickly detected by referring to the indexes.

Abstract: A liquid discharging device includes a plurality of liquid discharge sections. Each liquid discharge section includes a reservoir, a nozzle that discharges a solution supplied from the reservoir, and discharge energy generating means that generates energy to discharge the solution from the nozzle. The number of the liquid discharge sections corresponds to the number of probe types to be formed. The nozzles are two-dimensionally arranged. Using this liquid discharging device, probe liquids are discharged from the corresponding reservoirs onto a solid-phase substrate to form a predetermined two-dimensional probe array of high-purity probes on the substrate. This process exhibits high reproducibility and processability, and the resulting probe array has high array density.

Abstract: Method of manufacture of probe carriers and an apparatus used for the method in which plural kinds of probes are arranged on a substrate by ejecting plural kinds of probe solutions containing probe materials specifically associable with target substances from a liquid ejecting device onto the substrate, wherein, when the probe solutions are ejected, the probe solutions ejected from the liquid ejection device are adhered on the base in elongated state following front ends of the solutions without splitting of the probe solutions on the way to the substrate. The method and the apparatus can provide probe carriers with areas and shapes of very high uniformity arranged on probe carrier bases.

Abstract: A method for identifying an unknown base sequence present in a target single-stranded nucleic acid utilizing a probe array in which single-stranded nucleic acid probes are arranged as isolated spots on a substrate, where each probe has a base sequence complementary to one of plural base sequences expected to be the unknown base sequence, and fluorescence pattern of a sample on the probe array is compared with template patterns to know the base sequence of the sample.

Abstract: Provided is a method of spotting a probe densely and efficiently on a surface of a solid support. A liquid containing a probe is attached to a solid support as droplets to form spots containing the probe on the solid support by an ink jet method.

Abstract: A reaction site array to be used in conducting a plurality of reactions between two or more kinds of substances in a liquid medium with a trace amount is provided. The reaction site array comprises a plurality of reaction sites separated each other, each of the reaction sites is composed of a first region and a second region, the second region is raised from the first region to separate the first regions each other, and the first region has an affinity to the liquid medium and the second region has an affinity to the liquid medium lower than that of the first region. A preparation process of the reaction site and a reaction process using the reaction site array are also provided.

Abstract: Provided is a method of spotting a probe densely and efficiently on a surface of a solid support. A liquid containing a probe is attached to a solid support as droplets to form spots containing the probe on the solid support by an ink jet method.