Abstract: Provided is a method for producing an electrophotographic photosensitive member including an undercoat layer, the method including preparing a coating liquid for an undercoat layer containing: a titanium oxide particle; a polyol resin; a blocked isocyanate compound in which a structure represented by the formula (1) or the formula (2) is bonded to an isocyanate group; and a monohydric alcohol represented by the formula (3): where R11 and R12 each independently represent an alkyl group having 1 to 4 carbon atoms, and * represents a bonding site capable of being bonded to the isocyanate group; where R21 and R22 each independently represent an alkyl group having 1 to 4 carbon atoms, and * represents a bonding site capable of being bonded to the isocyanate group; and HO—R3??(3) where R3 represents an alkyl group having 1 to 4 carbon atoms.

Abstract: An electrophotographic photosensitive member includes a support and an undercoat layer on the support. The undercoat layer contains a metal oxide particle. The metal oxide particle contains a compound represented by any one of the formulae (A-1) to (A-10) and a compound represented by any one of the formulae (B-1) and (B-2) on the surface thereof.

Abstract: An electrophotographic photosensitive member includes an undercoat layer containing a resin and a metal oxide particle whose surface has been treated with a compound represented by formula (1), and the resin is a polymerized product of a composition containing a compound having a group represented by formula (2) and a polyol.

Abstract: An inspection apparatus capable of facilitating reduction in cost of the apparatus is provided. The inspection apparatus includes: beam generation means for generating any of charged particles and electromagnetic waves as a beam; a primary optical system that guides the beam into an inspection object held on a movable stage in a working chamber and irradiates the inspection object with the beam; a secondary optical system that detects secondary charged particles occurring from the inspection object; and an image processing system that forms an image on the basis of the detected secondary charged particles. The inspection apparatus further includes: a linear motor that drives the movable stage; and a Helmholtz coil that causes a magnetic field for canceling a magnetic field caused by the linear motor when the movable stage is driven.

Abstract: The electron beam apparatus is provided with a stage for mounting a sample thereon, a primary optical system for generating an electron beam having an irradiation area and irradiating the electron beam onto the sample, a secondary optical system for detecting electrons which have been generated through the irradiation of the electron beam onto the sample and have acquired structural information of the sample and acquiring an image of the sample about a viewing area and an irradiation area changing section for changing the position of the irradiation area with respect to the viewing area.

Abstract: An organic electroluminescent device is provided and includes: a pair of electrodes; and a light emitting layer between the electrodes. The organic electroluminescent device has a layer containing a compound represented by formula (I). L represents a divalent linking group, Q1 and Q2 each independently represents an aromatic or aliphatic heterocycle coordinated to Pt through a nitrogen atom, X1 represents a 6-membered ring containing one or more nitrogen atoms, Q1, Q2, and X1 each independently may have a substituent, X2 represents a sulfur atom, a phosphorus atom, an oxygen atom, or a nitrogen atom, and X3 represents a carbon atom, a sulfur atom, or a phosphorus atom.

Abstract: The present invention is intended to provide a pharmaceutical product for inhibiting expression of at least one lipid metabolism related mRNA selected from the group consisting of Angptl4 mRNA, SCD-1 mRNA, and SREBP1c mRNA, the present invention is also intended to provide a preventive and/or therapeutic agent for various diseases based on inhibition of expression of at least one lipid metabolism related mRNA selected from the group consisting of Angptl4 mRNA, SCD-1 mRNA, and SREBP1c mRNA, and the present invention relates to an agent for inhibiting expression of at least one lipid metabolism related mRNA selected from the group consisting of Angptl4 mRNA, SCD-1 mRNA, and SREBP1c mRNA, and relates also to a preventive and/or therapeutic agent for various diseases based on the inhibition of the expression of at least one lipid metabolism related mRNA selected from the group consisting of Angptl4 mRNA, SCD-1 mRNA, and SREBP1c mRNA, the agent comprising a compound represented by Formula (I), its salt, or a solva

Abstract: The object of the present invention is to provide a compound which is useful as a production intermediate of pyrazine carboxamide derivative such as 6-fluoro-3-hydroxy-2-pyrazine carboxamide. The present invention provides a pyrazino[2,3-d]isoxazole derivative represented by the formula (I): wherein X represents a halogen atom, a hydroxyl group or a sulfamoyloxy group, and Y represents —C(?O)R or —CN; wherein R represents a hydrogen atom, an alkoxy group an aryloxy group, an alkyl group, an aryl group or an amino group.

Abstract: The present invention is intended to provide a pharmaceutical product for inhibiting expression of at least one lipid metabolism related mRNA selected from the group consisting of Angptl4 mRNA, SCD-1 mRNA, and SREBP1c mRNA, the present invention is also intended to provide a preventive and/or therapeutic agent for various diseases based on inhibition of expression of at least one lipid metabolism related mRNA selected from the group consisting of Angptl4 mRNA, SCD-1 mRNA, and SREBP1c mRNA, and the present invention relates to an agent for inhibiting expression of at least one lipid metabolism related mRNA selected from the group consisting of Angptl4 mRNA, SCD-1 mRNA, and SREBP1c mRNA, and relates also to a preventive and/or therapeutic agent for various diseases based on the inhibition of the expression of at least one lipid metabolism related mRNA selected from the group consisting of Angptl4 mRNA, SCD-1 mRNA, and SREBP1c mRNA, the agent comprising a compound represented by Formula (I), its salt, or a solva

Abstract: According to an electric power steering system of the present invention, a bearing support housing member supporting at least one rolling bearing is preferably formed of a resin which can be continuously used in a temperature environment ranging from ?40° C. to 85° C., which is made of a resin composition containing a fibrous filler ranging from 30% by mass to 55% by mass, which has a coefficient of linear expansion ranging from 1.2×10?5 to 5.5×10?5 (1/° C.) in both a fiber direction and a perpendicular direction to the fiber direction in a temperature range from 23° C. to 80° C., and which has a coefficient of water absorption equal to or less than 4% when being left in water at a temperature of 23° C. for 24 hours.

Abstract: An inspection apparatus capable of facilitating reduction in cost of the apparatus is provided. The inspection apparatus includes: beam generation means for generating any of charged particles and electromagnetic waves as a beam; a primary optical system that guides the beam into an inspection object held on a movable stage in a working chamber and irradiates the inspection object with the beam; a secondary optical system that detects secondary charged particles occurring from the inspection object; and an image processing system that forms an image on the basis of the detected secondary charged particles. The inspection apparatus further includes: a linear motor that drives the movable stage; and a Helmholtz coil that causes a magnetic field for canceling a magnetic field caused by the linear motor when the movable stage is driven.

Abstract: In accordance with an embodiment, an analysis apparatus includes a secondary electron optical system, at least one detector, and a composition analysis unit. The secondary electron optical system includes a charged particle beam source and a lens. The charged particle beam source generates a charged particle beam and irradiates a sample with it. The lens controls a focal position and a trajectory of the charged particle beam using an electric field or a magnetic field. The detector detects a characteristic X-ray from the sample. The composition analysis unit analyzes a composition of a material constituting the sample from the detected characteristic X-ray. Each detector is arranged in such a manner that at least part of a detection surface thereof is placed on the same plane as an exit surface of the secondary electron optical system, or placed on the charged particle beam side of the same plane.

Abstract: An electrophotographic photoconductor has a support medium, an undercoat layer formed immediately on the support medium, and a photosensitive layer formed immediately on the undercoat layer, in which the undercoat layer contains a binding resin and composite particles each containing a core material particle covered with tin oxide doped with a predetermined amount of aluminum.

Abstract: An electro-optical inspection apparatus is provided that is capable of preventing adhesion of dust or particles to the sample surface as much as possible. A stage (100) on which a sample (200) is placed is disposed inside a vacuum chamber (112) that can be evacuated to vacuum, and a dust collecting electrode (122) is disposed to surround a periphery of the sample (200). The dust collecting electrode (122) is applied with a voltage having the same polarity as a voltage applied to the sample (200) and an absolute value that is the same or larger than an absolute value of the voltage. Thus, because dust or particles such as particles adhere to the dust collecting electrode (122), adhesion of the dust or particles to the sample surface can be reduced. Instead of using the dust collecting electrode, it is possible to form a recess on a wall of the vacuum chamber containing the stage, or to dispose on the wall a metal plate having a mesh structure to which a predetermined voltage is applied.

Abstract: In a transport carriage system, multiple transport carriages travel along a common track and each transport carriage includes a servo system that performs servo control with respect to traveling of the transport carriage, and an intermediate instruction of the servo system is generated in a predetermined cycle by an acceleration/deceleration control unit of a traveling control unit. A smoothed instruction is generated for the predetermined cycle by smoothing the generated intermediate instruction over a plurality of cycles with a smoothing unit of the traveling control unit, and the servo system is controlled based on the smoothed instruction that was generated.

Abstract: There is provided a screening method including administering or irradiating lymphoid cells with a cytotoxic factor that injures the lymphoid cells; incubating the lymphoid cells administered or irradiated with the cytotoxic factor for a predetermined time; measuring cell size of the lymphoid cells after the incubation; and determining influence of the cytotoxic factor on the lymphoid cells based on the cell size. According to this method, influence or drug efficacy of radiation, a radiation-protecting agent, an antioxidant, a radiation-sensitizing agent, a drug or ultraviolet rays can be economically and objectively determined in a short period of time.

Abstract: Provided is an electrophotographic photosensitive member capable of suppressing a voltage fluctuation and occurrence of a black spot under a high-temperature/high-humidity environment. The electrophotographic photosensitive member includes: a support; a first intermediate layer formed on the support; a second intermediate layer formed on the first intermediate layer; and a photosensitive layer formed on the second intermediate layer, in which the first intermediate layer contains metal oxide particles having a number-average primary particle diameter of from 30 to 450 nm; and the second intermediate layer contains a cured product of a composition containing an electron transport substance having a polymerizable functional group represented by the formula (1) or (2), and having a molecular weight of from 100 to 1,000, and a crosslinking agent having 3 to 6 groups reactive with the polymerizable functional group represented by the formula (1) or (2), and having a molecular weight of from 200 to 1,300.

Abstract: Provided is a method of producing an electrophotographic photosensitive member having improved sensitivity and capable of outputting an image having less image defects due to a ghost phenomenon not only under a normal-temperature, normal-humidity environment but also under a low-temperature, low-humidity environment as a particularly severe condition. The method of producing a gallium phthalocyanine crystal includes subjecting a gallium phthalocyanine and a specific amine compound, which are added to a solvent, to a milling treatment to perform crystal transformation of the gallium phthalocyanine. In addition, the gallium phthalocyanine crystal is used in the photosensitive layer of the electrophotographic photosensitive member.

Abstract: Provided is a method of producing an electrophotographic photosensitive member having improved sensitivity and capable of outputting an image having less image defects due to a ghost phenomenon not only under a normal-temperature, normal-humidity environment but also under a low-temperature, low-humidity environment as a particularly severe condition. The method of producing a gallium phthalocyanine crystal includes subjecting a gallium phthalocyanine and a specific amine compound, which are added to a solvent, to a milling treatment to perform crystal transformation of the gallium phthalocyanine. In addition, the gallium phthalocyanine crystal is used in the photosensitive layer of the electrophotographic photosensitive member.

Abstract: A substrate is irradiated by primary electrons and secondary electrons generated from the substrate are detected by a detector. A reference die is placed on the stage to obtain a pattern matching template image including feature coordinates of the reference die. A pattern matching is performed with an arbitrary die in a row or column including the reference die using the template image to obtain feature coordinates of the arbitrary die. An angle of misalignment is calculated between the direction of the row or column including the reference die and one of the directions of movement of the substrate on the basis of the feature coordinates of the arbitrary die and those of the reference die. The stage is rotated to correct the angle of misalignment to conform the direction of the row or column including the reference die with the one of the directions of movement of the substrate.