Abstract: A method, system and non-transitory computer-readable medium for automated reconstruction of an application. The method, the system, and the non-transitory computer-readable medium cause a processor: receive a workflow that comprises a sequence of microservice operations that correspond to the application; transfer, from a current host platform that is associated with the application, to a backup memory, a copy of an active database that is associated with the application; deactivate the active database from the current host platform; rebuild an operating system of the application; remove a pre-build configuration of the application; install a recovery mode of the application on the current host platform; deploy a post-build configuration of the application; perform a quality assurance process that comprises validating the post-build configuration of the application; and transfer from the backup memory to the current host platform, the copy of the active database.

Abstract: Resetting an integrated circuit (IC) by reset circuit of the IC comprises receiving a clock signal and a data signal. A sequence of bits of the data signal is stored in a memory based on the clock signal. A test mode signal is received and the sequence of bits is decoded in response to receiving the test mode signal. One of adjusting a counter value of a counter of the reset circuitry and outputting a reset signal corresponding to the counter value is performed based on the decoded sequence of bits.

Abstract: A method for creating a spatio-temporal schedule includes receiving a set of available work crews and a set of workorders to be scheduled, sequencing the set of workorders, wherein each workorder of the set of workorders is associated with a geographic location, a start time and an end time, and iterating through the set of available work crews, assigning a plurality of workorders of the set of workorders fully allocating a current crew before selecting a next crew, until all work crews are fully allocated and/or all workorders are assigned, wherein the assignment of workorders for a given work crew generates a route comprising the plurality of workorders.

Abstract: Routines are used to connect bot queries entered via a bot interface and database queries executed on a database. Each routine is associated with routine configurations, including (a) query attributes associated with bot queries that trigger the routine, (2) a database query executed or to be executed for the routine, and/or (3) display settings for displaying information returned from the database query in a bot response. Each routine is configured to generate an output structured data object (SDO) indicating information returned from the database query and the display settings applicable to the information. The output SDOs from the various routines are transmitted to the bot application via a single API endpoint. The routine configurations are entered by a design user through one or more design user interfaces rendered by an integrative configuration application module.

Abstract: A throttle control and safety switch device that serves the dual function of adjusting a throttle of an ATV (all-terrain vehicle) while turning off the engine in the event of failure of a throttle cable or if the throttle cable is stuck, is disclosed. The throttle control and safety switch device includes an operating lever connected to a pivot shaft for pivotal movement about an axis (A-A?). A first carrier connected to the pivot shaft includes a safety switch and a cable attachment portion to engage a throttle actuating cable. The safety switch transmits a cutoff signal to an electronic control unit (ECU) upon actuation by a plunger portion of a second carrier pivotally connected to the pivot shaft via fastener and connected to the first carrier via a dowel and slot arrangement.

Abstract: The present invention provides an ophthalmic composition comprising a combination of mydriatic agent and anti-muscarinic agent along with pharmaceutically acceptable excipients, wherein the pH of the composition is in the range of 3.5 to 8.5. The ophthalmic composition of the present invention has synergistic mydriasis effect to induce pupil dilation (Mydriasis) in ophthalmic surgery for pre-operative preparation.

Abstract: A method for creating a spatio-temporal schedule includes receiving a set of available work crews and a set of workorders to be scheduled, sequencing the set of workorders, wherein each workorder of the set of workorders is associated with a geographic location, a start time and an end time, and iterating through the set of available work crews, assigning a plurality of workorders of the set of workorders fully allocating a current crew before selecting a next crew, until all work crews are fully allocated and/or all workorders are assigned, wherein the assignment of workorders for a given work crew generates a route comprising the plurality of workorders.

Abstract: An example method comprises receiving historical sensor data of a first time period, the historical data including sensor data of a renewable energy asset, extracting features, performing a unsupervised anomaly detection technique on the historical sensor data to generate first labels associated with the historical sensor data, performing at least one dimensionality reduction technique to generate second labels, combining the first labels and the second labels to generate combined labels, generating one or more models based on supervised machine learning and the combined labels, receiving current sensor data of a second time period, the current sensor data including sensor data of the renewable energy asset, extracting features, applying the one or more models to the extracted features of the current sensor data to create a prediction of a future fault in the renewable energy asset, and generating a report including the prediction of the future fault in the energy asset.

Abstract: A system and method of managing a network with assets are described. The method includes generating a directed graph with each of the assets represented as a node, determining individual failure probability of each node, computing downstream failure probability of each node according to an arrangement of the nodes in the directed graph, computing upstream failure probability of each node according to the arrangement of the nodes in directed graph, and computing network failure probability for each node based on the corresponding individual failure probability, the downstream failure probability, and the upstream failure probability. Managing the network is based on the network failure probability of the assets.

Abstract: Systems and methods for conducting designated reactions that include a fluidic network having a sample channel, a reaction chamber, and a reservoir. The sample channel is in flow communication with a sample port. The system also includes a rotary valve that has a flow channel and is configured to rotate between first and second valve positions. The flow channel fluidically couples the reaction chamber and the sample channel when the rotary valve is in the first valve position and fluidically couples the reservoir and the reaction chamber when the rotary valve is in the second valve position. A pump assembly induces a flow of a biological sample toward the reaction chamber when the rotary valve is in the first valve position and induces a flow of a reaction component from the reservoir toward the reaction chamber when the rotary valve is in the second valve position.

Abstract: A computer system is providing financial recommendations for investors with preferences for non-financial characteristics, by measuring the dependence of a client's financial risk-aversion on non-financial factors referred to as ‘context specific risk-aversion’, and using the context-specific risk-aversion to compute recommended financial securities for investment. Amongst the non-financial factors (contexts) are those related to the values-based factors, often those relating to the environmental, social, or governance (ESG) performance of corporations. On a client computer system, a user interface is provided that displays a stochastic financial outcome with coincident (fixed or stochastic) non-financial outcome(s) forming a context, and displays an input field where the client user inputs data encoding their degree of acceptance for the outcomes presented thus risk-preference. The client computer system transmits the encoded context specific risk preferences to a communicatively coupled server system.

Abstract: An example of a flow cell includes a substrate, a plurality of chambers defined on or in the substrate, and a plurality of depressions defined in the substrate and within a perimeter of each of the plurality of chambers. The depressions are separated by interstitial regions. Primers are attached within each of the plurality of depressions, and a capture site is located within each of the plurality of chambers.

Abstract: An example of a flow cell includes a substrate, which includes nano-depressions defined in a surface of the substrate, and interstitial regions separating the nano-depressions. A hydrophobic material layer has a surface that is at least substantially co-planar with the interstitial regions and is positioned to define a hydrophobic barrier around respective sub-sets of the nano-depressions.

Abstract: Described herein are systems and methods for analyzing biological samples. Including a method for processing an analyte, comprising providing a fluidic device comprising the analyte and one or more polymer precursors; selecting a discrete area within said fluidic device; providing an energy source in optical communication with fluidic device; and selectively supplying a unit of energy generated from the energy source to the fluidic device to generate a polymer matrix within the fluidic device, wherein the polymer matrix is within the discrete area or adjacent to the discrete area.

Abstract: The present invention provides a method for reducing the protein aggregation by adjusting the pH below 6.0 of liquid formulation comprising the antibody or fusion protein. The present invention also provides methods for storing the pre-formulation for longer period without using any sugar or additives which can be utilized for preparation of liquid or lyophilized formulation.

Abstract: The system and methods discussed herein provide for filtering out noisy application signatures to improve the precision of first packet application classification. In some implementations, the system receive application signatures from devices along with their network identifiers. Based upon the frequency at which identical application signatures appear as originating from distinct network environments, the system determines the validity of application signatures and avoids storing irrelevant information for routing network traffic.

Abstract: An example of a flow cell includes a substrate, a plurality of chambers defined on or in the substrate, and a plurality of depressions defined in the substrate and within a perimeter of each of the plurality of chambers. The depressions are separated by interstitial regions. Primers are attached within each of the plurality of depressions, and a capture site is located within each of the plurality of chambers.

Abstract: An apparatus includes one or more valves adapted to be coupled to corresponding reagent reservoirs and a flow cell interface adapted to be coupled to a flow cell. The apparatus includes a sample cartridge interface having one or more ports and adapted to be coupled to a sample cartridge carrying a sample of interest. The sample cartridge interface positioned downstream of the flow cell interface. The apparatus includes a pump adapted to load a channel of the flow cell with the sample of interest via the flow cell interface associated with an outlet of the flow cell and a corresponding port of the sample cartridge interface.

Abstract: Degradable polyester bead are described comprising a plurality of transposome complexes immobilized to the surface thereof, wherein each transposome complex comprises a transposase bound to a first polynucleotide and a second polynucleotide, wherein the first polynucleotide comprises a 3? portion comprising a transposon end sequence and a tag, and the second polynucleotide comprises a 5? portion that is complementary to and hybridized to the transposon end sequence, and wherein the polyester bead has a melting point of from 50° C. to 65° C. Flow cells and methods related to these polyester beads are described. Also described herein are compositions comprising a bead and at least one nanoparticle and methods of use of such compositions comprising transposome complexes immobilized to nanoparticles.

Abstract: An example method comprises receiving first historical data of a first time period and failure data, identifying at least some sensor data that was or potentially was generated during a first failure, removing the at least some sensor data to create filtered historical data, training a classification model using the filtered historical data, the classification model indicating at least one first classified state at a second period of time prior to the first failure indicated by the failure data, applying the classification model to second sensor data to identify a first potential failure state based on the at least one first classified state, the second sensor data being from a subsequent time period, generating an alert if the first potential failure state is identified based on at least a first subset of sensor signals generated during the subsequent time period, and providing the alert.