Abstract: A system and method for generating weather reports and the like which are precisely computed automatically for a particular individual user's geographic location and which are provided automatically to the individual user. A user establishes an individualized user profile in which the user defines a particular location of interest, a contact address, and optionally, a personalized activity weather condition profile, establishing a preferred weather condition profile for activities of interest. A detailed and accurate weather forecasting model is run to provide high geographical and temporal resolution forecast data. The resulting modeled forecast data may be constrained by an operator using a constrainer module. The high resolution forecast data is compared to the individual user profile and personalized weather report for the particular location, times, and conditions of interest are provided automatically to the individual, e.g., via e-mail and/or at a personalized internet web page.

Abstract: Derivatives of 6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonyl]-pyrrolidine-2-carboxylic acid amide which exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.

Abstract: Derivatives of [6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonylamino]-propionamide which exhibit good inhibitory effect upon the interaction of CAMs and Leukointegrins and are thus useful in the treatment of inflammatory disease.

Abstract: A system and method for generating storm warnings which are precisely tailored automatically for a particular individual or business user's geographic location of interest, which may be provided automatically to the individual user or business. The user establishes an individualized user profile, in which the user may define a particular location of interest and a contact address to which a personalized storm warning is to be delivered. The user may also establish a storm profile defining attribute characteristics of a storm for which the user desires a storm warning to be provided, and an amount of advanced warning to be provided by the personalized storm warning. A detailed and accurate storm track which includes information describing storm characteristics (severe weather conditions) as well as the current location and predicted track of movement of storm, is generated.

Abstract: A low viscosity lubricating oil composition having a CCS viscosity less than 3500 mPa.s at −25° C. and having no more than 0.16 mass % of phosphorus which comprises a dispersant, and a detergent of calcium or magnesium or both; and optionally a zinc dihydrocarbyldithiophosphate, a viscosity modifier, a pour point depressant and an antioxidant. The oil satisfies the Cummins M11 cross-head wear engine test specification in a low phosphorus and low viscosity formulation.

Abstract: A low viscosity lubricating oil composition having a CCS viscosity less than 3500 mPa.s at −25° C. and having no more than 0.16 mass % of phosphorus which comprises a dispersant, and a detergent of calcium or magnesium or both; and optionally a zinc dihydrocarbyldithiophosphate, a viscosity modifier, a pour point depressant and an antioxidant. The oil satisfies the Cummins M11 cross-head wear engine test specification in a low phosphorus and low viscosity formulation.

Abstract: A method treating or preventing inflammatory and immune cell-mediated diseases by the administration of certain novel and known small molecules.

Abstract: Novel compounds for the treatment of HIV-1 infection. These are 2-heteroary-5,11-dihydro-6H-dipyrido?3,2-b:2',3'-e!?1,4!diazepines of the formula ##STR1## wherein Z is oxygen, sulfur, .dbd.NCN or .dbd.NOR.sup.

Abstract: A method for preparing certain 4-alkyl-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-ones, which employs the following reaction scheme: ##STR1##

Abstract: A method treating or preventing inflammatory and immune cell-mediated diseases by the administration of certain novel and known small molecules.