Patents by Inventor Thijs Kaper

Thijs Kaper has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BETA-GLUCOSIDASE I VARIANTS WITH IMPROVED PROPERTIES
    Publication number: 20170145396
    Abstract: The present disclosure is generally directed to enzymes and in particular beta-glucosidase variants. Also described are nucleic acids encoding beta-glucosidase variants, compositions comprising beta-glucosidase variants, methods of using beta-glucosidase variants, and methods of identifying additional useful beta-glucosidase variants.
    Type: Application
    Filed: August 29, 2016
    Publication date: May 25, 2017
    Applicant: DANISCO US INC.
    Inventors: Richard R. BOTT, Thijs KAPER, Bradley R. KELEMEN, Frits GOEDEGEBUUR, Ronaldus Wilhelmus Joannes HOMMES, Slavko KRALJ, Paulien KRUITHOF, Igor NIKOLAEV, Wilhelmus Antonious Hendricus VAN DER KLEY, Johannes Franciscus Thomas VAN LIESHOUT, Sander VAN STIGT THANS, Gudrun VOGTENTANZ, Mats SANDGREN
  • Cellulase variants with improved expression, activity and stability, and use thereof
    Patent number: 9523087
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof.
    Type: Grant
    Filed: February 25, 2014
    Date of Patent: December 20, 2016
    Assignee: DANISCO US INC
    Inventors: Wolfgang Aehle, Richard R. Bott, Benjamin S. Bower, Jonathan Caspi, David A. Estell, Frits Goedegebuur, Ronaldus Wilhelmus Joannes Hommes, Thijs Kaper, Bradley R. Kelemen, Slavko Kralj, Johannes Franciscus Thomas Van Lieshout, Igor Nikolaev, Sander Van Stigt Thans, Louise Wallace, Gudrun Vogtentanz, Mats Sandgren
  • VARIANTS OF CELLOBIOHYDROLASES
    Publication number: 20160272959
    Abstract: Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.
    Type: Application
    Filed: December 10, 2013
    Publication date: September 22, 2016
    Applicant: Danisco US Inc.
    Inventors: Richard R. BOTT, Maria FOUKARAKI, Ronaldus Wilhelmus HOMMES, Thijs KAPER, Bradley R. KELEMEN, Slavko KRALJ, Igor NIKOLAEV, Mats SANDGREN, Johannes Franciscus Thomas VAN LIESHOUT, SANDER VAN STIGT THANS
  • Beta-glucosidase I variants with improved properties
    Patent number: 9447400
    Abstract: The present disclosure is generally directed to enzymes and in particular beta-glucosidase variants. Also described are nucleic acids encoding beta-glucosidase variants, compositions comprising beta-glucosidase variants, methods of using beta-glucosidase variants, and methods of identifying additional useful beta-glucosidase variants.
    Type: Grant
    Filed: November 19, 2010
    Date of Patent: September 20, 2016
    Assignee: DANISCO US INC.
    Inventors: Richard R. Bott, Thijs Kaper, Bradley Kelemen, Frits Goedegebuur, Ronaldus Wilhelmus Hommes, Slavko Kralj, Paulien Kruithof, Igor Nikolaev, Wilhelmus Antonious Hendricus Van Der Kley, Johannes Franciscus Thomas Van Lieshout, Sander Van Stigt Thans, Gudrun Vogtentanz, Mats Sandgren
  • VARIANTS OF CELLOBIOHYDROLASES
    Publication number: 20160201104
    Abstract: Disclosed are a number of homologs and variants of Hypocrea jecorina Ce17A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.
    Type: Application
    Filed: December 10, 2013
    Publication date: July 14, 2016
    Applicant: DANISCO US INC.
    Inventors: Richard R. BOTT, Maria FOUKARAKI, Ronaldus Wilhelmus HOMMES, Thijs KAPER, Bradley R. KELEMEN, Slavko KRALJ, Igor NIKOLAEV, Mats SANDGREN, Johannes Franciscus Thomas VAN LIESHOUT, SANDER VAN STIGT THANS
  • VARIANT ENZYMES
    Publication number: 20160186155
    Abstract: Disclosed are glycosyl hydrolase enzyme variants, particularly variants of certain oxidoreductases of glycosyl hydrolase family 61. Nucleic acids encoding the glycosyl hydrolyase variants, compositions including the glycosyl hydrolase variants, methods of producing the variants, and methods of using the variants are also described.
    Type: Application
    Filed: July 24, 2014
    Publication date: June 30, 2016
    Inventors: Nicholai DOUGLAS, Maria FOUKARAKI, Ronaldus Wilhelmus HOMMES, Thijs KAPER, Bradley R. KELEMEN, Slavko KRALJ, SUZANNE E. LANTZ, Jonathan K. LASSILA, Igor NIKOLAEV, Daniel Esteban TORRES-PAZMINO, Wilhelmus VAN DER KLEY, Johannes Franciscus Thomas VAN LIESHOUT, SANDER VAN STIGT THANS
  • VARIANT ENZYMES
    Publication number: 20160177281
    Abstract: Disclosed are glycosyl hydrolase enzyme variants, particularly variants of certain oxidoreductases of glycosyl hydrolase family 61. Nucleic acids encoding the glycosyl hydrolyase variants, compositions including the glycosyl hydrolase variants, methods of producing the variants, and methods of using the variants are also described.
    Type: Application
    Filed: July 24, 2014
    Publication date: June 23, 2016
    Inventors: Maria FOUKARAKI, Ronaldus Wilhelmus HOMMES, Thijs KAPER, Bradley R. KELEMEN, Slavko KRALJ, SUZANNE E. LANTZ, IGOR NIKOLAEV, Wilhelmus VAN DER KLEY, Johan Franciscus Thomas VAN LIESHOUT, SANDER VAN STIGT THANS
  • NOVEL GLYCOSYL HYDROLASE ENZYMES AND USES THEREOF
    Publication number: 20160177279
    Abstract: The present disclosure is generally directed to glycosyl hydrolase enzymes, compositions comprising such enzymes, and methods of using the enzymes and compositions, for example for the saccharification of cellulosic and hemicellulosic materials into sugars.
    Type: Application
    Filed: July 27, 2015
    Publication date: June 23, 2016
    Applicant: DANISCO US INC.
    Inventors: Benjamin BOWER, Megan Yee HSI, Thijs KAPER, Bradley R. KELEMEN, Suzanne E. LANTZ, Edmund A. LARENAS, Colin MITCHINSON, Steven KIM, William D. HITZ, Mark EMPTAGE, Keith Dumont WING
  • VARIANT ENZYMES
    Publication number: 20160168550
    Abstract: Disclosed are glycosyl hydrolase enzyme variants, particularly variants of certain oxidoreductases of glycosyl hydrolase family 61. Nucleic acids encoding the glycosyl hydrolyase variants, compositions including the glycosyl hydrolase variants, methods of producing the variants, and methods of using the variants are also described.
    Type: Application
    Filed: July 24, 2014
    Publication date: June 16, 2016
    Inventors: Maria FOUKARAKI, Ronaldus Wilhelmus HOMMES, Thijs KAPER, Bradley R. KELEMEN, Slavko KRALJ, SUZANNE E. LANTZ, IGOR NIKOLAEV, Wilhelmus VAN DER KLEY, Johannes Franciscus Thomas VAN LIESHOUT, SANDER VAN STIGT THANS
  • VARIANTS OF CELLOBIOHYDROLASES
    Publication number: 20160122735
    Abstract: Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.
    Type: Application
    Filed: December 10, 2013
    Publication date: May 5, 2016
    Applicant: Danisco US Inc.
    Inventors: Richard R. BOTT, Maria FOUKARAKI, Ronaldus Wilhelmus HOMMES, Thijs KAPER, Bradley R. KELEMEN, Slavko KRALJ, Igor NIKOLAEV, Mats SANDGREN, Johannes Franciscus Thomas VAN LIESHOUT, Sander VAN STIGT THANS
  • VARIANTS OF CELLOBIOHYDROLASES
    Publication number: 20160122734
    Abstract: Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.
    Type: Application
    Filed: December 10, 2013
    Publication date: May 5, 2016
    Applicant: DANISCO US INC.
    Inventors: Richard R. BOTT, Maria FOUKARAKI, Ronaldus Wilhelmus HOMMES, Thijs KAPER, Bradley R. KELEMEN, Slavko KRALJ, Igor NIKOLAEV, Mats SANDGREN, Johannes Franciscus Thomas VAN LIESHOUT, SANDER VAN STIGT THANS
  • COMPOSITIONS AND METHODS COMPRISING CELLULASE VARIANTS WITH REDUCED AFFINITY TO NON-CELLULOSIC MATERIALS
    Publication number: 20150329842
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having reduced binding to non-cellulosic materials. Also described are nucleic acids encoding the cellulase, compositions comprising said cellulase, methods of identifying cellulose variants and methods of using the compositions.
    Type: Application
    Filed: March 19, 2015
    Publication date: November 19, 2015
    Applicant: Danisco US Inc.
    Inventors: Luis CASCAO-PEREIRA, Thijs KAPER, Bradley R. KELEMEN, Amy D. LIU
  • VARIANTS OF CELLOBIOHYDROLASES
    Publication number: 20150315560
    Abstract: Disclosed are a number of homologs and variants of Hypocrea jecorina Cel7A (formerly Trichoderma reesei cellobiohydrolase I or CBH1), nucleic acids encoding the same and methods for producing the same. The homologs and variant cellulases have the amino acid sequence of a glycosyl hydrolase of family 7A wherein one or more amino acid residues are substituted and/or deleted.
    Type: Application
    Filed: December 10, 2013
    Publication date: November 5, 2015
    Applicant: Danisco US Inc.
    Inventors: Richard R. BOTT, Maria FOUKARAKI, Ronaldus Wilhelmus HOMMES, Thijs KAPER, Bradley R. KELEMEN, Slavko KRALJ, Igor NIKOLAEV, Mats SANDGREN, Johannes Franciscus Thomas VAN LIESHOUT, SANDER VAN STIGT THANS
  • Compositions and methods comprising cellulase variants with reduced affinity to non-cellulosic materials
    Patent number: 8999692
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having reduced binding to non-cellulosic materials. Also described are nucleic acids encoding the cellulase, compositions comprising said cellulase, methods of identifying cellulose variants and methods of using the compositions.
    Type: Grant
    Filed: July 6, 2012
    Date of Patent: April 7, 2015
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, Thijs Kaper, Bradley R. Kelemen, Amy D. Liu
  • CELLULASE VARIANTS WITH IMPROVED EXPRESSION, ACTIVITY AND STABILITY, AND USE THEREOF
    Publication number: 20140302585
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof.
    Type: Application
    Filed: February 25, 2014
    Publication date: October 9, 2014
    Applicant: DANISCO US INC.
    Inventors: Wolfgang AEHLE, Richard R. BOTT, Benjamin S. BOWER, Jonathan CASPI, David A. ESTELL, Frits GOEDEGEBUUR, Ronaldus Wilhelmus HOMMES, Thijs KAPER, Bradley R. KELEMEN, Slavko KRALJ, Johannes Franciscus Thomas VAN LIESHOUT, Igor NIKOLAEV, Sander VAN STIGT THANS, Louise WALLACE, Gudrun VOGTENTANZ, Mats SANDGREN
  • Cellulase variants with improved expression, activity and stability, and use thereof
    Patent number: 8679816
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having improved expression, activity and/or stability. Also described are nucleic acids encoding the cellulase variants, compositions comprising the cellulase variants, and methods of use thereof.
    Type: Grant
    Filed: June 3, 2010
    Date of Patent: March 25, 2014
    Assignee: Danisco US Inc.
    Inventors: Wolfgang Aehle, Richard R. Bott, Benjamin Bower, Jonathan Caspi, David A. Estell, Frits Goedegebuur, Ronaldus W. J. Hommes, Thijs Kaper, Bradley Kelemen, Slavko Kralj, Johan Van Lieshout, Igor Nikolaev, Sander Van Stigt Thans, Louise Wallace, Gudrun Vogtentanz, Mats Sandgren
  • CELLULASE COMPOSITIONS AND METHODS OF USING THE SAME FOR IMPROVED CONVERSION OF LIGNOCELLULOSIC BIOMASS INTO FERMENTABLE SUGARS
    Publication number: 20140073017
    Abstract: The present invention relates to compositions that can be used in hydrolyzing biomass such as compositions comprising a polypeptide having ?-glucosidase activity, methods for hydrolyzing biomass material, and methods for improving the stability and saccharification efficacy of a composition comprising such ?-glucosidase polypeptides and/or activity.
    Type: Application
    Filed: March 16, 2012
    Publication date: March 13, 2014
    Applicant: DANISCO US INC.
    Inventors: Thijs Kaper, Igor Nikolaev, Suzanne E. Lantz, Meredith K. Fujdala, Megan Y. Hsi
  • NOVEL GLYCOSYL HYDROLASE ENZYMES AND USES THEREOF
    Publication number: 20130177947
    Abstract: The present disclosure is generally directed to glycosyl hydrolase enzymes, compositions comprising such enzymes, and methods of using the enzymes and compositions, for example for the saccharification of cellulosic and hemicellulosic materials into sugars.
    Type: Application
    Filed: September 22, 2010
    Publication date: July 11, 2013
    Applicant: DANISCO US INC.
    Inventors: Benjamin Bower, Megan Yee Hsi, Thijs Kaper, Bradley R. Keleman, Suzanne E. Lantz, Edmund A. Larenas, Colin Mitchinson, Steven Kim, William D. Hitz, Mark Emptage, Keith Dumont Wing
  • FILAMENTOUS FUNGAL HOST STRAINS AND DNA CONSTRUCTS, AND METHODS OF USE THEREOF
    Publication number: 20130149742
    Abstract: The present disclosure relates to filamentous fungal host strains and recombinant DNA constructs for creation and use thereof. The filamentous fungal host strains are particularly useful for achieving reliable expression of recombinant enzymes and variants.
    Type: Application
    Filed: June 3, 2011
    Publication date: June 13, 2013
    Applicant: Danisco US Inc.
    Inventors: Benjamin S. Bower, Thijs Kaper, Bradley R. Kelemen
  • BETA-GLUCOSIDASE I VARIANTS WITH IMPROVED PROPERTIES
    Publication number: 20130143301
    Abstract: The present disclosure is generally directed to enzymes and in particular beta-glucosidase variants. Also described are nucleic acids encoding beta-glucosidase variants, compositions comprising beta-glucosidase variants, methods of using beta-glucosidase variants, and methods of identifying additional useful beta-glucosidase variants.
    Type: Application
    Filed: November 19, 2010
    Publication date: June 6, 2013
    Applicant: Danisco US Inc.
    Inventors: Richard R. Bott, Thijs Kaper, Bradley Kelemen, Frits Goedegebuur, Ronaldus Hommes, Slavko Kralj, Paulien Kruithof, Igor Nikolaev