Abstract: A computing system receives a scheduled customer order and an unscheduled customer order from a first customer and a second customer, respectively. The scheduled order is associated with a pickup time at a store defined by the first customer. The unscheduled order is requested for immediate pickup by the second customer. A first picker mobile scanning device (MSD) and a second picker MSD are moved throughout the store by a first picker and a second picker, respectively. The computing system includes first picker data and second picker data indicating that the first picker MSD and the second picker MSD are configured to receive items from scheduled orders and unscheduled orders, respectively. The computing system is configured to assign items from the scheduled order and the unscheduled order to the first picker MSD and the second picker MSD based on the first picker data and the second picker data, respectively.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is present having a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier is adapted to contain a syringe with a hollow injection needle. The injector also has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. A control spring is arranged around the carrier for translating the carrier in a proximal direction (P) for insertion of the needle through the chassis into an injection site.

Abstract: Picker mobile scanning devices (MSDs) are associated with different pickers in a store. A computing system receives initial customer orders. The computing system assigns ordered items from the initial customer orders to the picker MSDs and stores a plurality of picker records, wherein each picker record includes data associated with a corresponding picker and picker MSD, and wherein each picker record includes an order limit number that indicates a number of different customer orders that can be assigned to the picker MSD. The computing system receives a new customer order including newly ordered items, determines a candidate set of pickers that have availability to receive newly ordered items based on the order limit numbers and a number of currently assigned customer orders associated with each of the pickers. The computing system selects a picker from the candidate set and assigns a set of newly ordered items to the selected picker.

Abstract: A system that uses one or more artificial intelligence models that predict an effect of a predicted event on a current state of the system. For example, the model may predict how a rate of change in time-series data may be altered throughout the first time period based on the predicted event.

Abstract: A system includes N location indicators and a mobile scanning device. The N location indicators are configured to be arranged throughout a store that includes a plurality of stocked items for picking according to one or more electronic customer orders. Each of the N location indicators is configured to transmit a different location signal. The mobile scanning device includes a display. The mobile scanning device is configured to wirelessly receive an electronic customer order comprising a plurality of ordered items indicating which of the stocked items are to be picked, detect at least one of the N location signals, and arrange at least some of the plurality of ordered items on the display based on which of the at least one of the N location signals is detected.

Abstract: Substituted quinazoline compounds, conjugates, and pharmaceutical compositions for use in the treatment of cancer are disclosed herein. The disclosed compounds are useful, among other things, in the inhibition of CDK. In certain aspects, the disclosure generally relates to substituted quinolinone amide compounds or salts of Formula (I), (IA), (IAA), (IAAA), (IB), (IBB), (IC), (ICC), (II), or (IIA) and pharmaceutical compositions thereof.

Abstract: An implement for use with an excavator includes a lightweight housing, a first coupling feature, a ground penetrating radar antenna, a controller, a wireless communication circuit and a rotation unit. The lightweight housing has an upper surface, a lower surface and a cavity. The first coupling feature is located on the upper surface and cooperates with a second coupling feature on an excavator arm. The ground penetrating radar antenna is mounted near the lower surface. The controller is mounted within the cavity and provides outgoing signals to the radar antenna, receives incoming signals from the radar antenna and interprets the incoming signals so as to provide implement output information. The wireless communication circuit is mounted within the cavity and transmits the implement output information. The rotation unit is mounted within the cavity and rotates the housing vis-à-vis the excavator arm.

Abstract: A video game includes a single player mode where completion of storyline objectives advances the single player storyline. The video game also includes a multiplayer mode where a plurality of players can play on an instance of a multiplayer map. Storyline objectives from the single player mode are selected and made available for completion to players in the multiplayer mode, and the single player storylines can be advanced by players completing respective storyline objectives while playing in the multiplayer mode. Combinations of storyline objectives are selected from pending storyline objectives for players connecting to a multiplayer game for compatibility with multiplayer maps. Constraints can be used to determine compatibility.

Abstract: Quantum dot devices with three of more accumulation gates provided over a single row of a quantum dot formation region are disclosed. Each accumulation gate is electrically coupled to a respective doped region. In this manner, multiple single electron transistors (SETs) are provided along the row. Side and/or center screening gates may be used to apply microwave pulses for qubit control and to control electrostatics so that source and drain regions of the multiple SETs with quantum dots formed along the single row of a quantum dot formation region are sufficiently isolated from one another. Such quantum dot devices provide strong spatial localization of the quantum dots, good control over quantum dot interactions and manipulation, good scalability in the number of quantum dots included in the device, and/or design flexibility in making electrical connections to the quantum dot devices to integrate the quantum dot devices in larger computing devices.

Abstract: Substituted aza-quinazoline compounds, conjugates, and pharmaceutical compositions for use in the treatment of cancer are disclosed herein. The disclosed compounds are useful, among other things, in the inhibition of CDK. In certain aspects, the disclosure generally relates to substituted quinolinone amide compounds or salts of Formula (I), (IA), (IAA), (IAAA), (IB), (IBB), (IC), (ICC), (ID), (IDD), (IE), and (IEE) and pharmaceutical compositions thereof.

Abstract: A system for detecting angle-of-arrival (AoA) includes a first device and at least one second device. The first device transmits a Bluetooth (BT) packet, and the second device receives the BT packet and determines an AoA of the BT packet. The second device includes a first radio-frequency (RF) antenna to receive a first RF signal and a second RF antenna to receive a second RF signal. The second device also includes a first BT core and a second BT-core and a processing circuit. The first BT core is coupled to the first RF antenna and is used to generate a first signal based on the first RF signal. The second BT core is coupled to the second RF antenna and generates a second signal based on the second RF signal. The processing circuit measures a phase difference between the first signal and the second signal and determines the AoA based on the phase difference.

Abstract: Given a set of therapeutic epitopes, a cassette sequence is designed to reduce the likelihood that junction epitopes are presented in the patient. The cassette sequence is designed by taking into account presentation of junction epitopes that span the junction between a pair of therapeutic epitopes in the cassette. The cassette sequence may be designed based on a set of distance metrics each associated with a junction of the cassette. The distance metric may specify a likelihood that one or more of the junction epitopes spanning between a pair of adjacent epitopes will be presented.

Abstract: Aluminum oxide (Al2O3) thin films having a high ?-phase purity and low defect density and methods for making the aluminum oxide thin films are provided. Also provided are epitaxial heterostructures that incorporate the aluminum oxide thin films as growth substrates and methods of forming the heterostructures. The Al2O3 films are pure, or nearly pure, ?-Al2O3. As such, the films contain no, or only a very low concentration of, other Al2O3 polymorph phases. In particular, the Al2O3 films contain no, or only a very low concentration of, the ?-Al2O3 polymorph phase.

Abstract: Systems and methods for stroke detection in accordance with embodiments of the invention are illustrated.

Abstract: An aircraft is provided. The aircraft includes a ducted wing portion and a fan chamber. The fan chamber is attached to a bottom of the ducted wing portion. A fan assembly is provided in the fan chamber and is operative to blow air through the ducted wing portion. The ducted wing portion is configured to direct air blown by the fan assembly down to provide lift for the aircraft.

Abstract: Systems and methods may use one or more artificial intelligence models that predict an effect of a predicted event on a current state of the system. The systems and methods may use one or more artificial intelligence models that predict an effect and/or occurrence of a predicted event based on the current state of the system. In order to generate responses that are both timely and pertinent (e.g., in a dynamic fashion), the system must determine, both quickly (i.e., in real-time or near real-time) and accurately, the predicted event.

Abstract: Systems and methods for distributed, automated management of brownfield real estate asset remediation and/or redevelopment, including at least one server computer for analyzing and providing recommendations for a potential brownfield investment, wherein the at least one server computer is paired with a web-based graphical interface for accessing and editing stored documents, pictures, tasks, and budget information related to at least one brownfield asset.

Abstract: A system includes N location indicators and a mobile scanning device. The N location indicators are configured to be arranged throughout a store that includes a plurality of stocked items for picking according to one or more electronic customer orders. Each of the N location indicators is configured to transmit a different location signal. The mobile scanning device includes a display. The mobile scanning device is configured to wirelessly receive an electronic customer order comprising a plurality of ordered items indicating which of the stocked items are to be picked, detect at least one of the N location signals, and arrange at least some of the plurality of ordered items on the display based on which of the at least one of the N location signals is detected.

Abstract: Methods and apparatus for efficient data transfer within a user space network stack. Unlike prior art monolithic networking stacks, the exemplary networking stack architecture described hereinafter includes various components that span multiple domains (both in-kernel, and non-kernel). For example, unlike traditional “socket” based communication, disclosed embodiments can transfer data directly between the kernel and user space domains. Direct transfer reduces the per-byte and per-packet costs relative to socket based communication. A user space networking stack is disclosed that enables extensible, cross-platform-capable, user space control of the networking protocol stack functionality. The user space networking stack facilitates tighter integration between the protocol layers (including TLS) and the application or daemon. Exemplary systems can support multiple networking protocol stack instances (including an in-kernel traditional network stack).

Abstract: A system for detecting angle-of-arrival (AoA) includes a first device and at least one second device. The first device transmits a Bluetooth (BT) packet, and the second device receives the BT packet and determines an AoA of the BT packet. The second device includes a first radio-frequency (RF) antenna to receive a first RF signal and a second RF antenna to receive a second RF signal. The second device also includes a first BT core and a second BT-core and a processing circuit. The first BT core is coupled to the first RF antenna and is used to generate a first signal based on the first RF signal. The second BT core is coupled to the second RF antenna and generates a second signal based on the second RF signal. The processing circuit measures a phase difference between the first signal and the second signal and determines the AoA based on the phase difference.