Patents by Inventor Thomas Hoffman

Thomas Hoffman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11925381
    Abstract: In accordance with an aspect of the present disclosure, a tissue extraction device may include a bag having an interior and a plurality of cutters elements extending along an interior surface of the bag. The cutters can be offset to facilitate collapsing of the bag prior to introducing the bag into a patient.
    Type: Grant
    Filed: March 31, 2022
    Date of Patent: March 12, 2024
    Assignee: Freyja Healthcare, LLC
    Inventors: James Bleck, John Aho, Thomas Eagan, Jonathan Towle, Mark Hoffman
  • Patent number: 11819022
    Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.
    Type: Grant
    Filed: August 29, 2022
    Date of Patent: November 21, 2023
    Assignees: Dow AgroSciences LLC, M.S. Technologies, L.L.C.
    Inventors: Yunxing C. Cui, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn M. Parkhurst, Sandra G. Toledo, Terry R. Wright, Sean M. Russell, Bruce Held, Vaithilingam Sekar
  • Publication number: 20230143169
    Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.
    Type: Application
    Filed: August 29, 2022
    Publication date: May 11, 2023
    Inventors: Yunxing C. CUI, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn M. Parkhursl, Sandra G. Toledo, Terry R. Wright, Sean M. Russell, Bruce Held, Vaithilingam Sekar
  • Publication number: 20230056359
    Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.
    Type: Application
    Filed: July 28, 2022
    Publication date: February 23, 2023
    Inventors: Yunxing C. Cui, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn M. Parkhurst, Sandra G. Toledo, Terry R. Wright, Sean M. Russell, Bruce Held, Vaithilingam Sekar
  • Publication number: 20220409148
    Abstract: The invention relates to a computer-assisted tomography (CT) system having the following features: a) at least one X-ray source, b) at least one patient couch for supporting a patient, c) at least one collimator in the ray path of the X-rays from the X-ray source through the patient, wherein a targeted X-ray from among the total X-ray radiation of the X-ray source is radiated by the collimator onto the patient, d) at least one X-ray detector, provided permanently or at least temporarily in the ray path of the targeted X-ray radiated by the collimator through the patient, e) at least one automatically actuable drive mechanism, using which the collimator can be moved with respect to the radiation direction of the targeted X-ray passing through the collimator, relative to the patient and/or to the X-ray detector, f) at least one electronic control device that is configured to automatically actuate the drive mechanism.
    Type: Application
    Filed: December 16, 2020
    Publication date: December 29, 2022
    Inventors: Georg ROSE, Thomas HOFFMAN, Mathias LEOPOLD, Oliver Großer, Maciej PECH
  • Patent number: 11425906
    Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.
    Type: Grant
    Filed: April 7, 2021
    Date of Patent: August 30, 2022
    Assignees: Dow AgroSciences LLC, M.S. Technologies, L.L.C.
    Inventors: Yunxing C. Cui, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn M. Parkhurst, Sandra G. Toledo, Terry R. Wright, Sean M. Russell, Bruce Held, Vaithilingam Sekar
  • Publication number: 20220256990
    Abstract: A hair scrunchie is described. The hair scrunchie may include a covering that includes a head and feet or other lower appendages located on opposite sides of an opening. The hair scrunchie may be movable between an expanded configuration and a collapsed configuration and may include a lock to maintain the hair scrunchie in a configuration until actuated by the user.
    Type: Application
    Filed: February 16, 2021
    Publication date: August 18, 2022
    Inventors: Thomas Hoffman Brown, Michael Edward Tant, JR., Jenna Harlander
  • Publication number: 20210323995
    Abstract: The present invention relates to isolithocholic acid (3ß-hydroxy-5ß-cholan-24-oic acid, iso-LCA) and isoallolithocholic acid (3ß-hydroxy-5?-cholan-24-oic acid) and their deuterated analogs for preventing or treating Clostridium difficile-associated disease in a mammalian subject.
    Type: Application
    Filed: August 8, 2019
    Publication date: October 21, 2021
    Applicant: PHENEX PHARMACEUTICALS AG
    Inventors: Christian Gege, Manfred Birkel, Thomas Hoffman
  • Publication number: 20210267198
    Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.
    Type: Application
    Filed: April 7, 2021
    Publication date: September 2, 2021
    Inventors: Yunxing C. Cui, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn M. Parkhurst, Sandra G. Toledo, Terry R. Wright, Sean M. Russell, Bruce Held, Vaithilingam Sekar
  • Patent number: 10973229
    Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.
    Type: Grant
    Filed: June 7, 2019
    Date of Patent: April 13, 2021
    Assignees: Dow Agrosciences LLC, M.S. Technologies, L.L.C.
    Inventors: Yunxing C. Cui, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn M. Parkhurst, Sandra G. Toledo, Terry R. Wright, Sean M. Russell, Bruce Held, Vaithilingam Sekar
  • Publication number: 20200093129
    Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.
    Type: Application
    Filed: June 7, 2019
    Publication date: March 26, 2020
    Inventors: Yunxing C. Cui, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn M. Parkhurst, Sandra G. Toledo, Terry R. Wright, Sean M. Russell, Bruce Held, Vaithilingam Sekar
  • Patent number: 10595456
    Abstract: A discharge device includes a plurality of material conveying components, an adjustable shear ledge, and an adjustable shroud to convey materials from a container of a material spreader out onto an open area. The adjustable shear ledge includes at least one longitudinal mounting member such that the adjustable shear ledge may be translated towards or away from the plurality of material conveying components to maintain a predetermined gap distance. The adjustable shroud may also be pivotably connected to the adjustable shear ledge such that the adjustable shroud can be pivoted towards or away from the plurality of material conveying components. The adjustable shear ledge and the adjustable shroud may be moved accordingly to maintain a preferred gap distance and to maintain concentricity with a swing of the material conveying components in order to reduce wear on components and promote spread performance of the material spreader.
    Type: Grant
    Filed: November 10, 2017
    Date of Patent: March 24, 2020
    Assignee: KUHN NORTH AMERICA, INC.
    Inventors: Thomas Hoffman, Todd Gibson, Patrick Henry, Claude McFarlane
  • Patent number: 10455834
    Abstract: Soybean event 9582.816.15.1 comprises genes encoding Cry1 F, Cry1 Ac (synpro), and PAT, affording insect resistance and herbicide tolerance to soybean crops containing the event, and enabling methods for crop protection and protection of stored products. Embodiments of the present disclosure relate to a new insect resistant and herbicide tolerant transgenic soybean transformation event, designated soybean event pDAB9582.816.15.1, comprising cry1 F v3 (cry1 F), cry1 Ac synpro (cry1 Ac) and pat v6 (pat), as described herein, inserted into a specific site within the genome of a soybean cell. Representative soybean seed has been deposited with American Type Culture Collection (ATCC) with the Accession No. ATCC Deposit No. PTA-12588. The DNA of soybean plants containing this event includes the junction/flanking sequences described herein that characterize the location of the inserted DNA within the soybean genome.
    Type: Grant
    Filed: June 25, 2013
    Date of Patent: October 29, 2019
    Assignee: Dow AgroSciences LLC
    Inventors: Nathan Bard, Gregory A. Bradfisch, Yunxing Cory Cui, James E. Dripps, Thomas Hoffman, Dayakar Pareddy, Dawn M. Parkhurst, Sandra G. Toledo, Barry Wiggins, Ning Zhou, Aaron T. Woosley
  • Patent number: 10400250
    Abstract: This invention relates in part to soybean event pDAB8264.44.06.1 and includes a novel expression cassettes and transgenic inserts comprising multiple traits conferring resistance to glyphosate, aryloxyalkanoate, and glufosinate herbicides. This invention also relates in part to methods of controlling resistant weeds, plant breeding and herbicide tolerant plants. In some embodiments, the event sequence can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. This invention further relates in part to endpoint TaqMan PCR assays for the detection of Event pDAB8264.44.06.1 in soybeans and related plant material. Some embodiments can perform high throughput zygosity analysis of plant material and other embodiments can be used to uniquely identify the zygosity of and breed soybean lines comprising the event of the subject invention. Kits and conditions useful in conducting these assays are also provided.
    Type: Grant
    Filed: January 5, 2017
    Date of Patent: September 3, 2019
    Assignees: Dow AgroSciences LLC, MS Technologies, L.L.C.
    Inventors: Yunxing C. Cui, Thomas Hoffman, Ning Zhou, Stephen N. Novak, Julissa Colon, Dawn M. Parkhurst, Sandra G. Toledo, Terry R. Wright, Sean M. Russell, Bruce Held, Vaithilingam Sekar
  • Patent number: 10207827
    Abstract: A habitation module that provides an artificial gravity environment. In one embodiment, the habitation module includes a rotating structure that rotates about an axis in relation to a stationary structure. The rotating structure includes a first gravity chamber that projects radially from the rotating structure, and a second gravity chamber that projects radially from the rotating structure in an opposite direction than the first gravity chamber. The first gravity chamber and the second gravity chamber are each comprised of a plurality of ring members that form side walls of the first gravity chamber and the second gravity chamber. The ring members are concentric so that the side walls of the first gravity chamber and the second gravity chamber radially extend and radially contract in upon themselves.
    Type: Grant
    Filed: June 26, 2017
    Date of Patent: February 19, 2019
    Assignee: The Boeing Company
    Inventors: Raju Dharmaraj, Thomas Hoffman, Craig Stanton, Patrick A. Swartzell
  • Publication number: 20180370661
    Abstract: A habitation module that provides an artificial gravity environment. In one embodiment, the habitation module includes a rotating structure that rotates about an axis in relation to a stationary structure. The rotating structure includes a first gravity chamber that projects radially from the rotating structure, and a second gravity chamber that projects radially from the rotating structure in an opposite direction than the first gravity chamber. The first gravity chamber and the second gravity chamber are each comprised of a plurality of ring members that form side walls of the first gravity chamber and the second gravity chamber. The ring members are concentric so that the side walls of the first gravity chamber and the second gravity chamber radially extend and radially contract in upon themselves.
    Type: Application
    Filed: June 26, 2017
    Publication date: December 27, 2018
    Inventors: Raju Dharmaraj, Thomas Hoffman, Craig Stanton, Patrick A. Swartzell
  • Publication number: 20180265483
    Abstract: Compounds of the formula (I) wherein, the substituents are as defined in claim 1, useful as a pesticides, especially as fungicides.
    Type: Application
    Filed: September 29, 2016
    Publication date: September 20, 2018
    Applicant: SYNGENTA PATRICIPATIONS AG
    Inventors: Daniel Stierli, Thomas Hoffman, Renaud Beaudegnies, Martin Pouliot
  • Patent number: 9944944
    Abstract: This invention includes a novel aad-12 transformation event for herbicide tolerance in soybean plants—referred to herein as pDAB4468-0416. This invention includes a heterologous polynucleotide inserted into a specific site within the genome of a soybean cell. In some embodiments, said event/polynucleotide can be “stacked” with other traits, including, for example, other herbicide tolerance gene(s) and/or insect-inhibitory proteins. Additionally, the subject invention provides assays for detecting the presence of the subject event in a sample (a soybean, for example). The assays can be based on the DNA sequence of the recombinant construct, inserted into the soybean genome, and on the genomic sequences flanking the insertion site. Kits and conditions useful in conducting the assays are also provided.
    Type: Grant
    Filed: November 24, 2010
    Date of Patent: April 17, 2018
    Assignee: Dow AgroSciences LLC
    Inventors: Yunxing C. Cui, Thomas Hoffman, Ning Zhou, Gregory J. Gilles, Terry R. Wright, Julissa Colon, Ricardo A. Barnes, Nathan J. VanOpdorp, Yonghe Bai
  • Publication number: 20180077854
    Abstract: A discharge device includes a plurality of material conveying components, an adjustable shear ledge, and an adjustable shroud to convey materials from a container of a material spreader out onto an open area. The adjustable shear ledge includes at least one longitudinal mounting member such that the adjustable shear ledge may be translated towards or away from the plurality of material conveying components to maintain a predetermined gap distance. The adjustable shroud may also be pivotably connected to the adjustable shear ledge such that the adjustable shroud can be pivoted towards or away from the plurality of material conveying components. The adjustable shear ledge and the adjustable shroud may be moved accordingly to maintain a preferred gap distance and to maintain concentricity with a swing of the material conveying components in order to reduce wear on components and promote spread performance of the material spreader.
    Type: Application
    Filed: November 10, 2017
    Publication date: March 22, 2018
    Applicant: KUHN NORTH AMERICA, INC.
    Inventors: Thomas Hoffman, Todd Gibson, Patrick Henry, Claude McFarlane
  • Patent number: 9832922
    Abstract: A discharge device includes a plurality of material conveying components, an adjustable shear ledge, and an adjustable shroud to convey materials from a container of a material spreader out onto an open area. The adjustable shear ledge includes at least one longitudinal mounting member such that the adjustable shear ledge may be translated towards or away from the plurality of material conveying components to maintain a predetermined gap distance. The adjustable shroud may also be pivotably connected to the adjustable shear ledge such that the adjustable shroud can be pivoted towards or away from the plurality of material conveying components. The adjustable shear ledge and the adjustable shroud may be moved accordingly to maintain a preferred gap distance and to maintain concentricity with a swing of the material conveying components in order to reduce wear on components and promote spread performance of the material spreader.
    Type: Grant
    Filed: February 13, 2015
    Date of Patent: December 5, 2017
    Assignee: KUHN NORTH AMERICA, INC.
    Inventors: Thomas Hoffman, Todd Gibson, Patrick Henry, Claude McFarlane