Abstract: The application relates to a vibration sounding device including: a housing body with a containment cavity and a sounding unit arranged in the containment cavity. The sounding unit includes a vibration system and a magnetic circuit system. The magnetic circuit system includes a main magnet and a secondary magnet assembly. The vibration sounding device also includes an elastic assembly, a weight assembly, and a drive coil. The second direction is perpendicular to the first direction. By virtue of the configuration, it is beneficial to simplify the forming process of the weight assembly, reduce the production cost, and also facilitate the replacement of the drive coil.

Abstract: A shell structure of a clothing treating device comprises a rear U-shaped plate, the rear U-shaped plate being bent at two vertical lines to form a left side wall, a right side wall and a rear side wall of a shell, with a cross section being U-shaped. The left side wall and the right side wall are respectively provided with at least one handle part, and the rear U-shaped plate is provided with an air vent communicating with an inside of the shell. As a result, the shell structure of a machine body of the clothing treating device is simplified, the strength is improved, and the assembly efficiency is improved. Also, an air duct arranged in the clothing treating device communicates with the air vent, so that the purpose of exchanging air with the outside through the air vent is realized.

Abstract: The present invention discloses a multi-energy complementary system for a co-associated abandoned mine and a use method. The multi-energy complementary system for a co-associated abandoned mine includes a mining mechanism, a grouting mechanism and an energy mechanism. In the present invention, the mining of coal and uranium resources is realized through the mining mechanism, the subsidence and seepage reduction of the stratum is realized through the grouting mechanism, and the effective utilization of waste resources is realized through the energy mechanism. Finally, with the efficient cooperation of the three mechanisms, safe and efficient development and utilization of co-associated resources in the full life cycle are realized, and the purposes of green and efficient mining of coal and uranium resources and secondary development of a coal seam goaf are achieved, thereby facilitating the realization of dual-carbon goals and the development of low-carbon green energy.

Abstract: The present invention provides a multifunctional sounding device including a housing, a first vibration system, a second vibration system, a magnetic circuit system, an elastic component and a flexible circuit board. The elastic component includes a deformation part fixed to the second vibration system and an installation part extended from both ends of the deformation part and fixed to the housing. The second vibration system is suspended in the containment cavity through the elastic component. The flexible circuit board is connected with the elastic component, so that the vibration of the flexible circuit board is coupled with the vibration of the elastic component. Therefore, the damping of the elastic component is reduced, the force received by the elastic component during vibration is reduced, and the service life of the elastic component is extended.

Abstract: The application discloses a vibration sounding device including a housing body with a containment cavity, a sounding unit placed in the containment cavity, a weight, a drive coil and a spring plate. The spring plate includes a first fixed section for fixed connection with the weight and a second fixed section for fixed connection with the housing body. The first fixed section and the second fixed section are fixed by laser spot welding. Compared with the prior art, the first fixed section and the second fixed section are fixed by laser spot welding, which can improve the bonding strength between the first fixed section and the second fixed section, and ensures the strength of the spring plate when the vibration sounding device is working.

Abstract: A shift-register unit, a grid driving circuit and a displaying device, which relates to the technical field of displaying. In the present disclosure, the oxide-semiconductor layers of the oxide thin-film transistors may be delimited into regions according to the total channel widths and the channel lengths required by the oxide thin-film transistors in the shift-register unit, wherein the sum of the widths of the independent semiconductor branches obtained by the delimitation is equal to the required total channel width. Accordingly, one oxide thin-film transistor can realize the required total channel width by using the one or more semiconductor branches, to ensure the normal operation of the oxide thin-film transistor, whereby the oxide-semiconductor layers of the different oxide thin-film transistors can be configured differently, to realize the purpose of reducing the border frame of the displaying device.

Abstract: Provided are transaminase mutants and uses thereof. The transaminase mutant is obtained by one or more amino acid mutations occurring in SEQ ID NO: 2 or is a mutant with a conserved amino acid mutation obtained by taking the sequence SEQ ID NO: 1 of a wild-type CvTA transaminase as a reference. Compared with wild-type transaminases, the catalytic activity of the mutant is improved to different degrees, so that the production efficiency of chiral amine compound synthesis may be improved.

Abstract: The capability to print to a portable document format (PDF) file is provided in a virtualized computing environment that supports a virtual desktop infrastructure (VDI). Printing-related properties, of local printers coupled to a client device, are provided to a host, so that virtual printers at the host can be configured with the printing-related properties. A simulator may be provided at the host to receive the printing-related properties from the client device and to receive a query from a virtualized computing instance for the printing-related properties, instead of the query being directly sent to the client device.

Abstract: Systems and methods for automated first arrival picking are disclosed. The method includes obtaining a seismic dataset composed of a plurality of seismic gathers and determining a pilot for each gather, where the pilot includes a position on an ordinate axis for each seismic trace representing a first arrival. The method continues iteratively until a stopping criterion is met by creating a preconditioned gather using the pilot, determining a differential pilot using global path tracing subject to a constraint and incrementing the pilot using the differential pilot to create a total picked first arrival. Once the stopping criterion has been met, the method further includes determining a final picked first arrival based on the total picked first arrival, determining a seismic velocity model from the final picked first arrival using a tomographic inversion and creating a seismic image using the seismic velocity model and the seismic dataset.

Abstract: A pulse diagnostic device and a system of pulse diagnosis are provided. The pulse diagnostic device includes a cuff and a main monitor. The cuff includes a tube and an air bag arranged with an air path interface. A gas medium is received in the air bag. The tube is connected to the air path interface. The main monitor includes a pressure sensor and a controller. The tube extends to reach the main monitor and is connected to the pressure sensor, and the pressure sensor further connects to the controller. When the pulse diagnostic device is working, the cuff contacts an artery, the pressure sensor senses a pressure of the gas medium in the tube. The pressure sensor transmits the pressure of the gas medium to the controller. The controller obtains the pulse information and the blood pressure information based on the pressure of the gas medium.

Abstract: An intelligent experimental device for collaborative mining of associated resources includes a signal transmission mechanism, a pressure maintaining mechanism, a feeding mechanism, and a reaction mechanism. The signal transmission mechanism includes a centralized controller, an annunciator, signal receivers, a power supply, a power cord, signal transmitters, and signal sensing valves. The pressure maintaining mechanism includes ambient and axial pressure oil chambers, ambient and axial pressure pumps, ambient and axial pressure liquid distribution tanks, a comprehensive pressure distribution pipe, and hydraulic transmission pipes. The feeding mechanism includes monitoring analyzers, temperature controllers, solution transfer pipes, seepage pumps, mixture conveying pipes, a comprehensive liquid distributor, an aggregate chamber, a liquid chamber, an oil chamber, a gas chamber, a mixing chamber and an analytical purifier.

Abstract: A surgical instrument (10) includes a housing (20) defining a longitudinal axis and a first assembly (200) and a second assembly (300) operably coupled to the housing (20). The first assembly (200) includes a first function button (200b) pivotably coupled to the housing (20) about a first pivot (200p) and a first circuit (210) supported by the housing (20) and aligned with the first pivot (200p). The first function button (200b) includes a first arm (201) on a first side of the first pivot (200p) and a second arm (202) on a second side of the first pivot (200p). The first circuit (210) is aligned with the cutting picot between the first arm (201) and the second arm (202) and includes a first actuator (211) on the first side of the first pivot (200p) and a second actuator (212) on the second side of the first pivot (200p).

Abstract: The present invention provides a multifunctional sounding device including a housing, a first vibration system, a second vibration system, a magnetic circuit system, an elastic component and a flexible circuit board. The elastic component includes a deformation part fixed to the second vibration system and an installation part extended from both ends of the deformation part and fixed to the housing. The second vibration system is suspended in the containment cavity through the elastic component. The flexible circuit board is connected with the elastic component, so that the vibration of the flexible circuit board is coupled with the vibration of the elastic component. Therefore, the damping of the elastic component is reduced, the force received by the elastic component during vibration is reduced, and the service life of the elastic component is extended.

Abstract: The present disclosure provides interferon receptor agonists with improved safety profiles and therapeutic indices. The interferon receptor agonists are attenuated through masking and/or reduced receptor binding as compared to a wild-type interferon. IFN receptor agonists optionally further comprise a targeting moiety, e.g., a targeting moiety that recognizes a tumor- or immune cell-associated antigen and directs the interferon receptor agonist to a tumor site and/or tumor-reactive immune cells. The disclosure further provides pharmaceutical compositions comprising the interferon receptor agonists, and methods of use of the interferon receptor agonists in therapy, as well as nucleic acids encoding the interferon receptor agonists, recombinant cells that express the interferon receptor agonists and methods of producing the interferon receptor agonists.

Abstract: The present invention discloses a refrigerator and a dedicated region module for a refrigeration apparatus, the refrigerator including a cabinet and a door for opening or closing the cabinet, a dedicated region module being provided on an inner side of the door facing the cabinet, and the dedicated region module having a receiving space for storing articles, the dedicated region module includes the electric component and a power module for supplying power to the electric component, such that a whole structure is simpler, and a manufacturing process is simpler.

Abstract: Provided are antibodies that specifically bind to T-cell immunoglobulin domain and mucin domain 3 (Tim-3). The anti-Tim-3 antibodies can be used to treat, prevent or diagnose immune, cancerous, infectious diseases or other pathological disorders that may be modulated by Tim-3-mediated functions.

Abstract: The present disclosure relates to the field of vehicle technology and provides an energy recovery control method, a system, and a vehicle. The method is applied in a vehicle, and the vehicle comprises a drive motor and a battery electrically connected to the drive motor; a first energy recovery torque curve with respect to the drive motor is pre-configured in the vehicle, and the first energy recovery torque curve is used to indicate a correspondence relationship between vehicle speed and energy recovery torque of the drive motor. The present disclosure performs reduction on a first energy recovery torque curve by means of utilizing a reduction ratio, allowing energy recovery in accordance with a relatively low torque strength when a usable charge power of the battery is unable to satisfy a preset power requirement corresponding to the first energy recovery torque curve.

Abstract: The present disclosure provides interferon receptor agonists with improved safety profiles and therapeutic indices. The interferon receptor agonists are attenuated through masking and/or reduced receptor binding as compared to a wild-type interferon. IFN receptor agonists optionally further comprise a targeting moiety, e.g., a targeting moiety that recognizes a tumor- or immune cell-associated antigen and directs the interferon receptor agonist to a tumor site and/or tumor-reactive immune cells. The disclosure further provides pharmaceutical compositions comprising the interferon receptor agonists, and methods of use of the interferon receptor agonists in therapy, as well as nucleic acids encoding the interferon receptor agonists, recombinant cells that express the interferon receptor agonists and methods of producing the interferon receptor agonists.

Abstract: This disclosure relates to IL-2 variants and methods of use thereof, including methods of treating or inhibiting a cancer or tumor. The IL-2 variants may have reduced ability in binding to or activating IL-2R?. The IL-2 variants may retain the ability in binding to or activating IL-2R? and/or IL-2R??. In addition, the IL-2 variants may have decreased Treg activity but maintain the capacity to activate NK cells and T effector cells.

Abstract: A model predictive virtual synchronous generator inverter control method considering a frequency-movement direction includes: obtaining a current frequency absolute value based on fundamental frequency of an inverter and a steady-state absolute value based on the fundamental frequency of the inverter; determining a frequency-movement state by comparing the above two absolute values: in a state of deviating from the fundamental frequency or a state of regressing to the fundamental frequency; setting a corresponding prediction output horizon according to the frequency-movement state, and constructing a cost function considering the frequency-movement state; and calculating an optimal virtual power increment value based on the cost function, then calculating an optimal virtual power, inputting the optimal virtual power to a swing equation of a virtual synchronous generator, and performing frequency adjustment according to an output value.