Abstract: Methods, apparatuses, and computer-readable media are set forth for visualizing and interacting with well production data in a three-dimensional or four-dimensional environment, e.g., using a volumetric well production display representation representing a well in an oilfield and including a plurality of display characteristics configured to display historical production data for the well over a time period.

Abstract: Provide are a detector module, a detector, and a medical device. The detector module includes a plurality of detection sub-modules at least partially arranged in a stepped manner in a first direction. Each of the plurality of detection sub-modules includes a plurality of photoelectric conversion units arranged at intervals in a second direction intersecting with the first direction. One of two adjacent detection sub-modules is located at a higher step as a first detection sub-module, and the other one is located at a lower step and as a second detection sub-module. A first gap is formed between the plurality of photoelectric conversion units of the first detection sub-module. A second gap is formed between the plurality of photoelectric conversion units of the second detection sub-module. A width of the first gap in the second direction is smaller than a width of the second gap in the second direction.

Abstract: The application relates to a vibration sounding device including: a housing body with a containment cavity and a sounding unit arranged in the containment cavity. The sounding unit includes a vibration system and a magnetic circuit system. The magnetic circuit system includes a main magnet and a secondary magnet assembly. The vibration sounding device also includes an elastic assembly, a weight assembly, and a drive coil. The second direction is perpendicular to the first direction. By virtue of the configuration, it is beneficial to simplify the forming process of the weight assembly, reduce the production cost, and also facilitate the replacement of the drive coil.

Abstract: Antigen binding molecules (ABMs) comprising Fab domains in non-native configurations, ABM conjugates comprising the ABMs and cytotoxic or cytostatic agents, pharmaceutical compositions containing the ABMs and ABM conjugates, methods of using the ABMs, ABM conjugates and pharmaceutical compositions for treating cancer, nucleic acids encoding the ABMs, cells engineered to express the ABMs, and methods of producing ABMs.

Abstract: Disclosed herein is a method for the prevention, delay of progression or treatment of cancer in a subject, comprising administering to the subject in need thereof a Btk inhibitor, particularly, (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo[1,5-a]pyrimidine-3-carboxamide or a pharmaceutically acceptable salt thereof, in combination with an immune checkpoint inhibitor or a targeted therapy agent. Also, disclosed a pharmaceutical combination comprising a Btk inhibitor, particularly, (S)-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetra-hydropyrazolo[1,5-a]pyrimidine-3-carboxamide or a pharmaceutically acceptable salt thereof, in combination with an immune checkpoint inhibitor, or a targeted therapy agent and the use thereof.

Abstract: The present invention discloses a multi-energy complementary system for a co-associated abandoned mine and a use method. The multi-energy complementary system for a co-associated abandoned mine includes a mining mechanism, a grouting mechanism and an energy mechanism. In the present invention, the mining of coal and uranium resources is realized through the mining mechanism, the subsidence and seepage reduction of the stratum is realized through the grouting mechanism, and the effective utilization of waste resources is realized through the energy mechanism. Finally, with the efficient cooperation of the three mechanisms, safe and efficient development and utilization of co-associated resources in the full life cycle are realized, and the purposes of green and efficient mining of coal and uranium resources and secondary development of a coal seam goaf are achieved, thereby facilitating the realization of dual-carbon goals and the development of low-carbon green energy.

Abstract: The present disclosure provides a speaker including a housing and a vibration system and a magnetic circuit unit that are received in the housing. The magnetic circuit unit includes lower clamp plate and magnetic circuit assembly arranged on lower clamp plate. A central area of lower clamp plate abuts against bottom wall of the housing. An edge area of lower clamp plate is spaced from the bottom wall. The edge area is provided with flange portion bending and extending from lower clamp plate toward the bottom wall. The flange portion abuts against the bottom wall. The flange portion abuts against the bottom wall. In this way, when speaker falls off, flange portions come in contact with bottom wall, such that stability of magnetic circuit unit can be improved, then operational performance and service life can be improved.

Abstract: Provided are antibodies that specifically bind to Programmed Death-1 (PD1, Pdcd-1, or CD279) and inhibit PD1-mediated cellular signaling and activities in immune cells, antibodies binding to a set of amino acid residues required for its ligand binding, and uses of these antibodies to treat or diagnose cancer, infectious diseases or other pathological disorders modulated by PD1-mediated functions.

Abstract: The disclosure relates to a control method and system for braking backup in autonomous driving, a computer storage medium, a computer device, and a vehicle. The control method for braking backup in autonomous driving according to an aspect of the disclosure includes: receiving a status indication of an execution module associated with braking and a status indication of a function module associated with stability control; determining, based at least in part on the received status indication of the execution module associated with braking and the received status indication of the function module associated with stability control, a braking capability of the execution module associated with braking; and assigning a braking command based at least in part on the received status indication of the execution module associated with braking and the determined braking capability of the execution module associated with braking.

Abstract: An aerial system, including a processing system, an optical system, an actuation system and a lift mechanism, includes an autonomous photography and/or videography system 70, implemented, at least in part, by the processing system 22, the optical system 26, the actuation system 28 and the lift mechanism 32. The autonomous photograph and/or videography system performs the steps of establishing a desired flight trajectory, detecting a target, controlling the flight of the aerial system as a function of the desired flight trajectory relative to the target using the lift mechanism and controlling the camera to capture pictures and/or video.

Abstract: Provided is a speaker, including a frame; a vibration unit fixed to the frame; and a magnetic circuit unit driving the vibration unit to vibrate and produce sound. The vibration unit includes a diaphragm and a voice coil; the diaphragm includes a first suspension, a second suspension and a vibrating portion; the magnetic circuit unit is provided with a magnetic gap, and the voice coil is inserted in the magnetic gap; the magnetic circuit unit includes a yoke; and the yoke and the diaphragm are arranged at two opposite sides of the frame; and the vibration unit further includes a fixing ring connected to the magnetic circuit unit; the second suspension surrounds the fixing ring; and an inner peripheral side of the second suspension is fixed to an end of the fixing ring away from the yoke. With this structure, the acoustic performance of the speaker can be improved.

Abstract: Implementations of the present disclosure relate to broadcast of intrusion detection information. A method comprises detecting, by an access point (AP), at least one device in a wireless communication network to be an illegal device. the method also comprises obtaining, by the AP, intrusion detection information related to the at least one device, the intrusion detection information comprising at least one identifier of the at least one device. The intrusion detection information related to the at least one device is broadcasted. In this way, when other devices in the network receive the intrusion detection information, they would know about the malicious activity or policy violations in the network, and would know which device(s) is detected to be illegal.

Abstract: Disclosed are systems and methods for centralized monitoring of connected devices within a network. The system includes multiple dashboard graphical user interfaces (“Dashboards”) that aggregate multiple monitoring platforms into a single interface. The Dashboards display a wide variety of critical system network monitoring metrics. The Dashboards are generated utilizing network monitoring data and metrics received from a virtual service engine platform deployed within a monitored network. The virtual service engine platform itself incorporates a multitude of monitoring software platforms and applications that capture a wide range of useful network monitoring metrics and data from the digital resources that comprise a monitored information technology network.

Abstract: The present disclosure relates to IL27 receptor agonists with improved therapeutic profiles.

Abstract: An unmanned aerial system includes a remote controller device and an unmanned aerial vehicle. A user input on the remote controller device indicates a flight command requested by a user. The remote controller device determines a current position and/or orientation of the remote controller device in response to the flight command from the user. The current position and/or orientation is sent to the vehicle. The vehicle responsively determines a desired orientation of the unmanned aerial vehicle as a function of the current position and/or orientation of the remote controller device and operates a lift mechanism to execute a flight operation based on the desired orientation of the unmanned aerial vehicle and the current position of the remote controller device.

Abstract: The present disclosure relates to the field of energy storage, and provides a rapid-response energy storage system and a using method thereof.

Abstract: Provided is a speaker, including a frame, a vibration unit fixed to the frame; and a magnetic circuit unit driving the vibration unit to vibrate and produce sound. The vibration unit includes a diaphragm and a voice coil; the diaphragm includes a first suspension, a second suspension and a vibrating portion; the magnetic circuit unit includes a magnetic gap, and the voice coil is inserted in the magnetic gap; the magnetic circuit unit includes a yoke; and the vibration unit further includes a fixing ring connected to the magnetic circuit unit; an inner peripheral side of the second suspension is fixed to an outer side of the fixing ring; and a connection position of the second suspension and the fixing ring is located between two opposite ends of the fixing ring along a vibrating direction of the diaphragm. With this structure, sealing performance of the speaker is improved.

Abstract: The present invention discloses a microcapsule powder stable in gastric acid, a method for preparing the same and use thereof. The microcapsule powder comprises a core material and a capsule material coated outside the core material, wherein the capsule material has a melting point of greater than 42° C., and the capsule material does not decompose or dissolve under the action of protease and gastric acid, but decomposes under the action of intestinal digestive enzymes. The core material is coated with the capsule material in the microcapsule powder, thus achieving high-efficiency coating of the core material by a single component. The microcapsule powder achieves conventional intragastric stability as well as favorable stability in an open environment at room temperature, thus solving the problem that the conventional embedding solution may only achieve intragastric stability, but the stability in an open environment at room temperature is low.

Abstract: A contact lens system includes a shared antenna electrode, an accommodation actuator to provide variable optical power, and a controller coupled to the accommodation actuator and the shared antenna electrode. The controller including logic for arbitrating access to the shared antenna electrode between an impedance sensor and a communication circuit; selectively establishing an oscillator with the impedance sensor and the shared antenna electrode; correlating an oscillation condition of the oscillator to an accommodation setting; and adjusting the variable optical power of the accommodation actuator based upon the accommodation setting. An impedance across the shared antenna electrode varies based upon an amount an eyelid overlaps the contact lens system when the contact lens system is worn on an eye.

Abstract: The present disclosure relates to IL2 agonists with improved therapeutic profiles.