Abstract: The present disclosure provides a biosensor having improved sensitivity. The present disclosure also provides a base material for manufacturing a sensor for analyzing a detection object, said base material comprising a molecularly imprinted polymer having: a molecularly imprinted recess in which a target of the detection object is received; and a group for binding a specific bondable molecule to the target, said group being provided inside the molecularly imprinted recess. The base material is characterized in that the group for binding the specific bondable molecule is a group suited for a small substance, and/or is characterized in that the molecularly imprinted recess has a shape or structure suited for a small substance.

Abstract: The purpose of the present invention is to provide: an artificial bio sensor that is easy to produce and that exhibits superior specificity; and a method for producing same. Nanoparticles according to the present invention for sensing use comprise a molecular imprint polymer having a molecular imprint space for biological matter. The molecular imprint polymer includes a structural unit derived from functional groups including an interaction group with respect to said biological matter and a signaling substance binding group different from said interaction group. The functional groups are present on the surface of the molecular imprint space. The nanoparticles are useful as an artificial biosensor that is easy to produce and exhibits superior specificity.

Abstract: A region recommendation device includes a usage information acquiring unit, an environmental information acquiring unit that acquires environmental information regarding an indoor environment in target regions, a non-environmental information acquiring unit, an information storage unit, and a recommended region determining unit. The usage information acquiring unit acquires usage information including at least one of past usage history of the target regions and current availability of the target regions. The non-environmental information acquiring acquires, as non-environmental information, at least one of biological information of a person in the target space and region feature information regarding equipment and peripheral information in the target regions. The information storage unit stores information acquired by the usage information acquiring unit, the environmental information acquiring unit, and the non-environmental information acquiring unit.

Abstract: A region recommendation device determines one or more recommended regions to be recommended to a target person from a plurality of target regions in a target space. The region recommendation device includes a region information acquiring unit that acquires region information regarding the target regions, a recommended region determining unit that determines the one or more recommended regions based on the region information, and a presenting unit. The presenting unit presents, to the target person, the one or more recommended regions and a recommendation reason used to determine the one or more recommended regions.

Abstract: A determination section of a sleep control apparatus determines an awakening point based on target data. The target data is time-series data of biological information of a target person in a target period. The target period is a period between wakefulness to failing asleep of the target person, or a period from the wakefulness of the target person to a time point at which a predetermined time has passed since the target person fell asleep. The controller controls a target device so that the target device stimulates the target person to wake up at the awakening point.

Abstract: The present invention provides a polymer replica of a target molecule, the polymer replica being capable of accurately inheriting surface information possessed by the target molecule in a molecular imprinting technique.

Abstract: A measurement system capable of detecting a detection target such as sEVs with high specificity and rapidity, and also having both high stability and improved binding activity. A base material for producing a sensor for analysis of a detection target, including: a base material; and a polymer film provided on a surface of the base material, wherein the polymer film includes a concave that receives the detection target, and, inside the concave, a group for signal substance's binding and a polynucleotide group for nucleic acid aptamer's binding.

Abstract: Provided is a convenient measurement system by which a target to be detected can be quickly recognized with high specificity. This base material for manufacturing a sensor for analyzing a detection target has: a base material; and a polymer film provided on the surface of the base material, wherein the polymer film has a concave that receives the detection target, and the concave has an antibody material bonding group and a signal material bonding group. A sensor for analyzing a detection target has: the base material for manufacturing a sensor for analyzing a detection target; an antibody material specific to the detection target and bonded to the antibody material bonding group; and a signal material that is bonded to the signal material bonding group.

Abstract: Provided is a molecular imprint polymer that is capable of acquiring stealth properties through a new mechanism. The molecular imprint polymer according to the present invention, which has a plasma protein recognition sites molecularly imprinted by a plasma protein thereon and contains a constituent derived from a biocompatible monomer, is an in vivo stealth nanoparticle to be used in intravascular delivery. As the plasma protein, albumin is preferred. When carrying a drug thereon, the in vivo stealth nanoparticle according to the present invention is usable as a drug for drug delivery system.

Abstract: An automatic analyzing apparatus 10 includes a chip rack 11 that stores a pipette chip, a pipette 12 into which a specimen is injected, a conveyance unit that conveys the pipette 12 by parallel translation, a reagent rack 14, a reaction unit 15, a detection unit 16, and a detection block unit 17. The pipette chip stored by the chip rack 11 has a planar structure to directly and optically detect the specimen. The chip rack 11 includes, in a hole that receives the pipette chip, a guide corresponding to the structure of the pipette chip. The pipette 12 sucks or discharges the specimen via the pipette chip mounted onto the tip thereof by a drive of a pump. In the detection unit 16, a measurement is carried out with the pipette chip arranged so that the plane that receives light is vertical to an optical axis.

Abstract: Provided is a molecular imprint polymer that is capable of acquiring stealth properties through a new mechanism. The molecular imprint polymer according to the present invention, which has a plasma protein recognition sites molecularly imprinted by a plasma protein thereon and contains a constituent derived from a biocompatible monomer, is an in vivo stealth nanoparticle to be used in intravascular delivery. As the plasma protein, albumin is preferred. When carrying a drug thereon, the in vivo stealth nanoparticle according to the present invention is usable as a drug for drug delivery system.

Abstract: An automatic analyzing apparatus 10 includes a chip rack 11 that stores a pipette chip, a pipette 12 into which a specimen is injected, a conveyance unit that conveys the pipette 12 by parallel translation, a reagent rack 14, a reaction unit 15, a detection unit 16, and a detection block unit 17. The pipette chip stored by the chip rack 11 has a planar structure to directly and optically detect the specimen. The chip rack 11 includes, in a hole that receives the pipette chip, a guide corresponding to the structure of the pipette chip. The pipette 12 sucks or discharges the specimen via the pipette chip mounted onto the tip thereof by a drive of a pump. In the detection unit 16, a measurement is carried out with the pipette chip arranged so that the plane that receives light is vertical to an optical axis.

Abstract: Molecular-template polymer particles for a steroid hormone, said molecular-template polymer particles comprising a polymer that interacts with said steroid hormone. The polymerization unit of said polymer preferably contains at least two functional groups that interact with the aforementioned steroid hormone.

Abstract: The method and apparatus for detecting a chemical substance of the present invention perform the detection of a chemical substance by capturing the chemical substance with a capturing body prepared by utilizing a molecular template. The present invention provides a chemical sensor easy to use for general consumers at home as well as for medical personnel (medical doctors, medical technicians and nurses). In particular, an object of the present invention is to diagnose the symptom of stress disorder by detecting, with high sensitivity, a steroid hormone such as cortisol closely related to stress disorder, and to herewith contribute to the prevention and early treatment of stress disorder. The present invention provides a molecular template for a steroid hormone, including a polymer to interact with the steroid hormone. The polymer preferably includes, in the polymerization unit thereof, two or more functional groups to interact with the steroid hormone.

Abstract: In an optical disk apparatus, by obtaining the temperature in the vicinity of a laser in the apparatus, the power source voltage of the laser driver is controlled such that power consumed by the headroom of the laser driver is reduced to the maximum extent without deteriorating the current drive characteristic of the headroom when the temperature becomes higher. The laser driving current of the laser driver is monitored to control the power source of the laser driver such that the power consumed by the headroom is possibly reduced while maintaining the current drive characteristic of the headroom for the monitored current.

Abstract: An authentication method for use in sending/receiving data between a coded data output apparatus for outputting coded data having a water mark, and a recording apparatus for recording data onto a recording medium, the method including: deciding a type of the recording medium used by the recording apparatus; based on a result of the deciding, selecting, from a plurality of authentication methods, an authentication method corresponding to the type of the recording medium, and conducting authentication between the coded data output apparatus and the recording apparatus, using the authentication method; sending/receiving data between the coded data output apparatus and the recording apparatus after conducting the authentication; and in a case where the coded data has the water mark, detecting the water mark by the coded data output apparatus, wherein the data exchanged between the coded data output apparatus and the recording apparatus is scrambled by a scrambling method corresponding to the type the recording me

Abstract: A method of reproducing data from a recording medium, each of the data including reference time information indicating a reference time and including packet data, the method including: reproducing the data from the recording medium; obtaining a difference between respective reference times indicated by the reference time information of the reproduced adjacent data; rearranging the data on a time axis such that a time interval between adjacent data is equal to the obtained reference time difference; and outputting the rearranged data.

Abstract: An authentication method for use in sending/receiving data between a coded data output apparatus for outputting coded data having a water mark, and a recording apparatus for recording data onto a recording medium, the method including: deciding a type of the recording medium used by the recording apparatus; based on a result of the deciding, selecting, from a plurality of authentication methods, an authentication method corresponding to the type of the recording medium, and conducting authentication between the coded data output apparatus and the recording apparatus, using the authentication method; sending/receiving data between the coded data output apparatus and the recording apparatus after conducting the authentication; and in a case where the coded data has the water mark, detecting the water mark by the coded data output apparatus, wherein the data exchanged between the coded data output apparatus and the recording apparatus is scrambled by a scrambling method corresponding to the type the recording me

Abstract: A disk-like recording medium recording/reproducing method or apparatus for performing a data recording operation and a data reproducing operation to the disk-like recording medium alternately. The recording operation is performed at a constant linear velocity, and whether a recording area at an ending point of an n-th recording operation on the medium is continuous to a recording area at a starting point of an (n+1) the recording operation is identified. When a discontinuation of the recording area is identified, the rotational speed at the starting point of the (n+1)th recording operation is changed, during a reproducing operation between the n-th recording operation and the (n+1)th recording operation. When a continuation of the recording area is identified, the rotational speed of the disk-like recording medium at the ending point of the n-th recording operation is held, during a reproducing operation between the n-th recording operation and the (n+1)th recording operation.

Abstract: Certain embodiments provide an image forming apparatus comprising an image forming part, a detection part, an arithmetic part, a storage device and an image quality maintaining control part. The image forming part forms an image quality maintaining adjustment pattern on a transfer belt to convey a sheet. The detection part detects the image quality adjustment pattern. The arithmetic part calculates, based on a detection result of the image quality maintaining adjustment pattern obtained by the detection part, image quality maintaining information for forming an image of desired image quality. The storage device stores the image quality maintaining information before the image forming apparatus transitions to a sleep mode. The image quality maintaining control part reads the image quality maintaining information from the storage device and controls the image forming part based on the read image quality maintaining information before the image forming apparatus returns after the sleep mode is released.