Patents by Inventor Toshikazu Nakamura

Toshikazu Nakamura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7838494
    Abstract: The present invention provides an agent comprising HGF for inducing differentiation of bone marrow cells into alveolar cells. The present invention also provides an HGF-containing agent for alveolar formation in pulmonary emphysema and the like in which alveoli are destroyed.
    Type: Grant
    Filed: March 7, 2005
    Date of Patent: November 23, 2010
    Assignees: Tohoku Technoarch Co., Ltd., Kringle Pharma Inc.
    Inventors: Hiroshi Kubo, Kota Ishizawa, Hidetada Sasaki, Toshikazu Nakamura
  • Publication number: 20100283625
    Abstract: In a remote operation apparatus of a working machine including a working machine side transmission/reception unit (21) and a radio remote operation means (3) having a remote control side transmission/reception unit (31), an ON/OFF control circuit (32) for controlling the operation/non-operation state of the remote control side transmission/reception unit (31) is disposed to the radio remote operation means (3), and the working machine side transmission/reception unit (21) is called when the remote control side transmission/reception unit (31) is in an operating state by that the ON/OFF control circuit (32) is turned on, and the data showing the driving state of the working machine (1) is transmitted from the working machine side transmission/reception unit (21) to the remote control side transmission/reception unit (31) to thereby reduce an electric power consumption amount on the radio remote operation means (3).
    Type: Application
    Filed: May 7, 2010
    Publication date: November 11, 2010
    Applicant: HONDA MOTOR CO., LTD.
    Inventors: Toshinori Inagawa, Toshikazu Nakamura
  • Patent number: 7827463
    Abstract: In a semiconductor memory device having an error-correction function: one or both of a portion of a set of data bits and a set of parity bits based on the set of data bits are held, where the set of data bits and the set of parity bits constitute a code for error correction and are written in memory cells in the leading write cycle in a burst write operation. The set of parity bits written in memory cells in the leading write cycle is updated in the final write cycle on the basis of the portion of the set of data bits and/or the set of parity bits, and another set of data bits required to be written in the final write cycle in the memory cells at the address at which the above portion is written in the leading write cycle.
    Type: Grant
    Filed: November 10, 2005
    Date of Patent: November 2, 2010
    Assignee: Fujitsu Semiconductor Limited
    Inventors: Shuzo Otsuka, Kuninori Kawabata, Toshikazu Nakamura, Akira Kikutake
  • Patent number: 7807177
    Abstract: The present invention provides a segment of glycosylation-deficient HGF having mutation(s) introduced into an amino acid sequence so as to prevent glycosylation at at least one glycosylation site of a hepatocyte growth factor (HGF), and a method of producing the same. The segment of glycosylation-deficient HGF of the present invention has the same activity as that of a segment of glycosylated HGF, therefore, it is useful as an alternate for a segment of glycosylated HGF.
    Type: Grant
    Filed: August 26, 2004
    Date of Patent: October 5, 2010
    Assignees: Kringle Pharma Inc.
    Inventors: Toshikazu Nakamura, Kunio Matsumoto, Kazuhiro Fukuta
  • Publication number: 20100222274
    Abstract: The invention provides a modified glycosylation-deficient HGF and a production method thereof. The glycosylation-deficient HGF is produced by introducing amino acid mutation(s) so that no glycosylation take place at at least one glycosylation site of hepatocyte growth factor.
    Type: Application
    Filed: March 12, 2010
    Publication date: September 2, 2010
    Inventors: Toshikazu Nakamura, Kunio Matsumoto, Kazuhiro Fukuta
  • Publication number: 20100220540
    Abstract: A semiconductor device includes a word line drive circuit for resetting the word line by driving the word line connected to a memory cell and is constituted so as to switch a reset level of the word line drive circuit, which is set at the time of the reset operation of the word line, between a first potential such as a ground potential and a second potential such as a negative potential. Further, a semiconductor device including a memory cell array formed by arranging a plurality of memory cells and a word line reset level generating circuit for generating a negative potential makes it possible to vary the amount of a current supply of the word line reset level generating circuit when non-selected word lines are set to a negative potential by applying the output of the word line reset level generating circuit to the non-selected word lines, and varies the amount of the current supply of the negative potential in accordance with the operation of the memory cell array.
    Type: Application
    Filed: March 5, 2010
    Publication date: September 2, 2010
    Applicant: FUJISU MICROELECTRONICS LIMITED
    Inventors: Masato Takita, Masato Matsumiya, Satoshi Eto, Toshikazu Nakamura, Masatomo Hasegawa, Ayako Kitamoto, Kuninori Kawabata, Hideki Kanou, Toru Koga, Yuki Ishii, Shinichi Yamada, Kaoru Mori
  • Patent number: 7755957
    Abstract: A semiconductor memory comprising an address transition detection circuit for detecting a transition of an address and outputs an address detection signal; an address input circuit for inputting an input address based upon the address detection signal; a command judgment circuit for decoding a command signal input and outputting a command judgment signal; a redundancy circuit for making a redundancy judgment based upon a redundancy judgment signal indicating timing of a redundancy judgment, wherein the redundancy circuit includes a redundancy judgment speed-up circuit for controlling an output of the redundancy judgment signal based upon a predetermined command signal.
    Type: Grant
    Filed: September 11, 2008
    Date of Patent: July 13, 2010
    Assignee: Fujitsu Semiconductor Limited
    Inventors: Toshikazu Nakamura, Tomohiro Kawakubo
  • Publication number: 20100168003
    Abstract: The present invention discloses an agent for treating a polyglutamine aggregation-caused disease or suppressing its onset, which comprises, as an active ingredient, (1) (i) HGF protein, (ii) a partial peptide of HGF protein that is substantially equivalent in activity to HGF protein, or a salt of either of them, or (2) DNA containing (i) DNA encoding HGF protein, (ii) DNA encoding a partial peptide of HGF protein that is substantially equivalent in activity to HGF protein or (iii) DNA which encodes a protein or a peptide that is substantially equivalent in activity to HGF protein and hybridizes with DNA comprising a complementary base sequence of either of the above-mentioned DNAs under a stringent condition.
    Type: Application
    Filed: March 30, 2007
    Publication date: July 1, 2010
    Applicants: Osaka University, Kringle Pharma, Inc.
    Inventors: Toshikazu Nakamura, Hiroshi Funakoshi, Daisuke Miyazawa, Kunio Iwatani
  • Patent number: 7741452
    Abstract: The invention provides a modified glycosylation-deficient HGF and a production method thereof. The glycosylation-deficient HGF is produced by introducing amino acid mutation(s) so that no glycosylation take place at at least one glycosylation site of hepatocyte growth factor.
    Type: Grant
    Filed: December 15, 2004
    Date of Patent: June 22, 2010
    Inventors: Toshikazu Nakamura, Kunio Matsumoto, Kazuhiro Fukuta
  • Publication number: 20100142306
    Abstract: A semiconductor memory includes: a voltage supply circuit which supplies a first voltage to a word line when an internal circuit is in a standby state, and supplies a second voltage higher than the first voltage to the word line when the internal circuit is in an active state; and a control circuit changes a drive capacity of the voltage supply circuit when changing from the standby state to the active state and the second voltage is supplied to the word line.
    Type: Application
    Filed: December 4, 2009
    Publication date: June 10, 2010
    Applicant: FUJITSU MICROELECTRONICS LIMITED
    Inventors: Toshikazu NAKAMURA, Atsushi Takeuchi, Atsushi Nakakubo
  • Publication number: 20100137217
    Abstract: A pharmaceutical preparation comprising a hepatocyte growth factor or a DNA molecule encoding the same and the like according to the present invention can suppress the fibrosis of a transplanted organ after organ transplantation. The present invention is useful in the fields of organ transplantation and regeneration therapy.
    Type: Application
    Filed: January 28, 2010
    Publication date: June 3, 2010
    Inventors: Jun Amano, Ken-ichi Ito, Kazuhiro Yamaura, Kunio Matsumoto, Toshikazu Nakamura
  • Patent number: 7706209
    Abstract: A semiconductor device, including a word line driver for driving a word line connected to a memory cell in a memory cell array and for resetting the word line when the memory cell changes from an activated to a standby state. The reset level of the word line driver is set when resetting of the word line is performed, and may be switched between first and second potentials. A word line reset level generating circuit varies the amount of negative potential current supply in accordance with memory cell array operating conditions. The semiconductor device includes a plurality of power source circuits, each having an oscillation circuit and a capacitor, for driving the capacitor via an oscillation signal outputted by the oscillation circuit. At least some power source circuits share a common oscillation circuit, and different capacitors are driven via the common oscillation signal.
    Type: Grant
    Filed: December 22, 2005
    Date of Patent: April 27, 2010
    Assignee: Fujitsu Microelectronics Limited
    Inventors: Masato Takita, Masato Matsumiya, Satoshi Eto, Toshikazu Nakamura, Masatomo Hasegawa, Ayako Kitamoto, Kuninori Kawabata, Hideki Kanou, Toru Koga, Yuki Ishii, Shinichi Yamada, Kaoru Mori
  • Patent number: 7696170
    Abstract: A pharmaceutical preparation comprising a hepatocyte growth factor or a DNA molecule encoding the same and the like according to the present invention can suppress the fibrosis of a transplanted organ after organ transplantation. The present invention is useful in the fields of organ transplantation and regeneration therapy.
    Type: Grant
    Filed: September 9, 2005
    Date of Patent: April 13, 2010
    Assignee: Kringle Pharma INC.
    Inventors: Jun Amano, Ken-ichi Ito, Kazuhiro Yamaura, Kunio Matsumoto, Toshikazu Nakamura
  • Publication number: 20100081617
    Abstract: Disclosed is a therapeutic agent effective for the fundamental treatment of a spinal cord injury and a demyelinating disease. Specifically disclosed are a therapeutic agent for a spinal cord injury and a therapeutic agent for a demyelinating disease, each of which comprises an HGF protein as an active ingredient.
    Type: Application
    Filed: August 27, 2009
    Publication date: April 1, 2010
    Applicants: KEIO UNIVERSITY, OSAKA UNIVERSITY, KRINGLE PHARMA, INC.
    Inventors: Hideyuki OKANO, Yoshiaki TOYAMA, Masaya NAKAMURA, Akio IWANAMI, Kazuya KITAMURA, Toshikazu NAKAMURA, Hiroshi FUNAKOSHI, Keigo HANADA
  • Patent number: 7688193
    Abstract: An oil level detection device for an internal combustion engine, which comprises: a housing permitting entry therein of oil; a float provided within the housing and vertically movable with the oil entered in the housing; a switch for performing switching operation in response to the vertical movement of the float within the housing; protrusions provided, on the upper surface of the float, for preventing the float from sticking to the ceiling of the housing due to viscosity of the oil; and protrusions provided, on the bottom of the housing, for preventing the float from sticking to the bottom of the housing due to viscosity of the oil.
    Type: Grant
    Filed: January 26, 2007
    Date of Patent: March 30, 2010
    Assignee: Honda Motor Co., Ltd.
    Inventors: Kazutomo Nishida, Kazumi Miyashita, Toshikazu Nakamura, Toru Taniguchi
  • Patent number: 7675773
    Abstract: An address switch circuit receives a row address signal supplied to a first address terminal group and a column address signal supplied to a second address terminal group. Further, the address switch circuit receives the row address signal supplied to the second address terminal group and thereafter receives the column address signal supplied to the second address terminal group and supplies the received row address signal and the received column address signal to the row decoder and the column decoder during a second operation mode. The number of semiconductor memories that are tested at once can be increased by executing an operation test of the semiconductor memories in the second operation mode. In addition, it becomes possible to test a semiconductor memory using test assets for other semiconductor memories. Consequently, the test efficiency can be improved, and the test cost can be reduced.
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: March 9, 2010
    Assignee: Fujitsu Microelectronics Limited
    Inventors: Kaoru Mori, Toshikazu Nakamura, Jun Ohno, Masaki Okuda
  • Publication number: 20100024544
    Abstract: A float-type oil-level detection apparatus is provided for detecting the surface of engine oil. A housing (81) for housing a float (82) has a through-hole (136) in the sidewall of the side opposite from the sidewall that faces the movement of the oil dipper (69).
    Type: Application
    Filed: June 16, 2006
    Publication date: February 4, 2010
    Applicant: HONDA MOTOR CO., LTD.
    Inventors: Yasunori Matsubara, Toshikazu Nakamura, Yoshihiro Iijima
  • Patent number: 7649446
    Abstract: A multipurpose engine controller comprises a control unit for switching between supplying and stopping power supplied from an ignition circuit to a spark plug on the basis of two states, i.e., the operating state of the multipurpose engine determined based on a detection signal from the engine speed sensor, and the state of the level of the oil inside the crankcase determined based on a detection signal from the float-type oil level sensor.
    Type: Grant
    Filed: January 26, 2007
    Date of Patent: January 19, 2010
    Assignee: Honda Motor Co., Ltd.
    Inventors: Kazumi Miyashita, Kazutomo Nishida, Toshikazu Nakamura, Toru Taniguchi
  • Patent number: 7618614
    Abstract: A method and compound for treatment of hydrocephalus is presented. Hepatocyte growth factor (HGF) is administered intraventricularly.
    Type: Grant
    Filed: November 19, 2004
    Date of Patent: November 17, 2009
    Assignee: Shinshu TLO Co., Ltd.
    Inventors: Tsuyoshi Tada, Toshikazu Nakamura
  • Publication number: 20090209463
    Abstract: An HGF precursor protein variant, in which a peptide structure comprises a sequence including a peptide chain X inserted between an ? chain of HGF or a polypeptide where 1 to 20 amino-acid residues from the C-terminus of the ? chain are deleted, and a ? chain of HGF or a polypeptide where 1 to 20 amino-acid residues from the N-terminus of the ? chain are deleted; wherein (i) the peptide chain X has an amino-acid sequence of at least two residues, (ii) the peptide chain X can be cleaved by a protease reaction or a chemical reaction, and (iii) a protein obtained by cleaving at least one site of the peptide chain X has HGF action.
    Type: Application
    Filed: March 30, 2007
    Publication date: August 20, 2009
    Inventors: Toshikazu Nakamura, Kunio Matsumoto, Kazuhiro Fukuta, Kiichi Adachi, Daichika Hayata