Abstract: A mouse cDNA library from gene fragments encoding proteins localizing at cell—cell junctions was screened by a technique visualizing localization of a protein to identify a junction-enriched and -associated protein, JEAP. GenBank homology search was performed based on the sequence. Based on the obtained sequence, a mouse cDNA library was screened to identify JEAP-2. By using prepared antibodies against these proteins, it was revealed that these proteins express specifically at tight junctions, in particular, tight junctions in exocrine glands.

Abstract: A PET resin container having an oxygen-capturing function and an improved level of oxygen barrier property is provided, with these performances being achieved by applying radiation to the container after the molding operation.

Abstract: An illumination device includes a control knob having a display portion, a tubular case combined with a back side of the control knob, a light guide plate attached to seal an upper opening of the tubular case, and LEDs disposed at a lower opening of the tubular case. Light emitted from the LEDs is applied to the display portion through the light guide plate. A plurality of retaining projections and a plurality of push-up projections are provided on an inner surface of the tubular case adjacent to the upper opening. An upper surface of an outer edge of the light guide plate is retained by lower ends of the retaining projections, and a lower surface of the outer edge is pushed up by upper ends of the push-up projections so that the light guide plate is held inside the tubular case while being bent upwardly.

Abstract: A synthetic resin container possessing a higher gas barrier property, and having a coating film (2) possessing a higher gas barrier property and positioned on an inner surface and/or and outer surface of the container body, wherein at least the coating film (2) is constituted of: an organic silicon compound layer (2a) positioned on the or each surface of the container body and including nitrogen, silicon, carbon, hydrogen, and oxygen; and a silicon oxide compound layer (2b) including a silicon oxide compound as a main component.

Abstract: A synthetic resin container possessing a higher gas barrier property, and having a coating film possessing a higher gas barrier property and positioned on an inner surface and/or outer surface of a body of the container, wherein the coating film (2) is constituted of a layered coating including at least a gas barrier coating (2a) and a cover coating (2b), the cover coating being positioned at a topmost side of the coating film. The cover coating (2b) includes a layer positioned at a topmost side of the cover coating and possessing such a water repellency that the layer has a contact angle with water of 80° to 100°. The layers (2a, 2b) constituting the coatings, respectively, are each formed by vapor deposition and each have a refractive index in a range of 1.3 to 1.6.

Abstract: The invention reduces power consumption and makes rotor with ease. As illustrated in FIG. 2, a multistage roots pump (1) in the invention including upstream rotors (R1a, R1b, R2a, R2b) having multiple teeth, supported by a pair of revolving shafts (A1, A2); and downstream rotors (R3a, R3b˜R5a, R5b) having identical number of teeth (31) with the upstream rotors, supported by revolving shafts (A1, A2). The discharge area formed by the outer periphery of the downstream rotors (R3a, R3b˜R5a, R5b) and the inner periphery of the pump chambers (P1˜P5) is smaller than that of the upstream rotors (R1a, R1b, R2a, R2b).

Abstract: A mouse cDNA library from gene fragments encoding proteins localizing at cell-cell junctions was screened by a technique visualizing localization of a protein to to identify a junction-enriched and -associated protein, JEAP. GenBank homology search was performed based on the sequence. Based on the obtained sequence, a mouse cDNA library was screened to identify JEAP-2. By using prepared antibodies against these proteins, it was revealed that these proteins express specifically at tight junctions, in particular, tight junctions in exocrine glands.

Abstract: The present invention is to provide a method for avoiding specifically and preventively or therapeutically an organ injury in graft-versus host disease (GVHD), a preventive or therapeutic agent therefore, and a method for screening the preventive or therapeutic agent. By inhibiting the interaction between fractalkine and the chemokine receptor CX3CR1 expressed on donor CD8 T cells, and by suppressing specifically organ infiltration by CD8 T cells to intestinal tract and the like, it may be possible to prevent organ injuries in GVHD, and to treat and prevent GVHD selectively. A method using an anti-fractalkine antibody can be exemplified to inhibit the interaction between fractalkine and the chemokine receptor CX3CR1. Moreover, the present invention encompasses a method for screening a substance having a preventive or therapeutic effect on an organ injury in GVHD, that can use a mechanism of the present invention for suppressing organ infiltration by CD8 T cells to intestinal tract or the like.

Abstract: A method for manufacturing a plasma display apparatus includes bonding a panel to a sustaining board (chassis) with a sufficient bonding area. In a process of bonding the panel to the chassis, the panel is supported on the sustaining board (chassis) via a heat conducting sheet. Then the panel and the chassis are sandwiched between resilient pressuring boards, which are larger than the panel and the chassis. After that, a predetermined pressure is applied from at least one of the pressuring boards, thereby bonding the panel to the chassis via a heat conducting sheet.

Abstract: Preliminarily sterilized contents are filed in a synthetic resin container, which has been subjected to rinsing and sterilization. In this instance, the contents are maintained at a filling temperature that is higher than normal temperature, but lower than a temperature expressing sterilization effect, so that the container is prevented from deformation, which took place inevitably when heating the aseptically filled contents.

Abstract: A method of normalizing contents of DNA fragments in a sample among respective DNA fragments, comprising: preparing DNA fragments in which adaptors each comprising an oligodeoxyribonucleotide are attached to both ends of each DNA fragment in the sample to form restriction enzyme recognition sites that do not exist in the DNA fragments in the sample, and at least a part between the restriction enzyme recognition sites at both ends, including the restriction enzyme recognition sites, is double-stranded; denaturing the prepared double-stranded DNA fragments; hybridizing the denatured DNA fragments under a condition that a part of the DNA fragments remains single-stranded; cleaving the hybridized double-stranded DNA fragments with a restriction enzyme having a cleavage site exclusively in the adaptors; and performing PCR using the obtained DNA fragments as templates and using a primer having a nucleotide sequence complementary to a nucleotide sequence of the adaptors before the cleavage; and a subtraction method

Abstract: A photosensor circuit comprises a photodiode PD, which converts a light signal into electricity, an n-channel MOS transistor QD1 which has a logarithmic characteristic in its weakly reversed condition and converts a sensor current generated by the photodiode PD into a detection voltage which has a logarithmic characteristic, and a capacitor which is connected to a detection terminal of this transistor QD1. A resetting voltage VG=VS is applied to the gate G of the transistor QD1 to lower the impedance between the drain and the source of the transistor for resetting the transistor to an initial condition. As the n-channel MOS transistor QD1 is a depletion type n-channel MOS transistor, when this transistor QD1 does not receive any gate voltage, the transistor stays in a weakly reversed condition and has a logarithmic characteristic. This photosensor circuit has a high SN ratio and is capable of detecting minute light signals in high precision.

Abstract: A PET resin container having an oxygen-capturing function and an improved level of oxygen barrier property is provided, with these performances being achieved by applying radiation to the container after the molding operation.

Abstract: An isolated novel type CC chemokine-like protein which is expressed from peripheral blood mononuclear cells under an immunological stimulus and has a cell migration activity; a DNA encoding the protein; an expression vector and a transformant containing the DNA; a process for producing a recombinant protein by using the transformant; and a pharmaceutical composition containing the protein.

Abstract: A method for manufacturing a plasma display apparatus for bonding a panel to a sustaining board with a sufficient bonding area. In a process of bonding the panel to a chassis, the panel is piled on the sustaining board via a heat conducting sheet, then the panel and the chassis are sandwiched between resilient pressuring boards, which are larger than the panel and the chassis. After that, a predetermined pressure is applied from at least one of the pressuring boards, thereby bonding the panel to the chassis via a heat conducting sheet.

Abstract: A mouse cDNA library from gene fragments encoding proteins localizing at cell-cell junctions was screened by a technique visualizing localization of a protein to to identify a junction-enriched and -associated protein, JEAP. GenBank homology search was performed based on the sequence. Based on the obtained sequence, a mouse cDNA library was screened to identify JEAP-2. By using prepared antibodies against these proteins, it was revealed that these proteins express specifically at tight junctions, in particular, tight junctions in exocrine glands.

Abstract: There are provided uses of an antibody directed to CX3CR1 and fractalkine. Killer lymphocytes can be readily identified, eliminated and separated by using an anti-CX3CR1 antibody. Further, there can be provided an antibody drug for suppressing chemotaxis and cytotoxic activity of killer lymphocytes by suppressing an interaction between CX3CR1 and fractalkine.

Abstract: Bias charge is injected from a bias power supply line 3 into a detecting electrode 11 constituting an electrostatic capacitance element between an object to be detected to accumulate charge in accordance with its electrostatic capacitance, and when the charge is distributed between the electrostatic capacitance element and a capacitance element 12 which has been reset to a reset potential, a holding voltage of the capacitance element 12 changes in accordance with the amount of charges accumulated in the detecting electrode 11, and thus a signal is outputted regarding the change in holding voltage as an amount of change in gate potential of a source follower amplifier element 13, thereby detecting the capacitance of the electrostatic capacitance element between the object to be detected and the detecting electrode 11.

Abstract: A current when static electricity intrudes is passed by a first circuit portion composed of a series circuit including a fuse element and a resistor until a program voltage is applied to a program voltage terminal, and the fuse element is fused when the program voltage is applied. A current for breaking the fuse element is passed when an N-type MOS transistor turns into a second breakdown state by a gate voltage from a second circuit portion.

Abstract: A photosensor signal processing apparatus is used in combination with an image sensor comprised of a matrix of pixels or photosensors capable of producing an output as a linear function and a logarithmic function of incident illumination. The apparatus includes a correction data storage device which stores therein a set of data about the respective photosensors for the correction of individual outputs of the photosensors, and a correcting device for correcting the respective output values of the photosensors on the basis of the correction data. Thus, even when the individual outputs of the photosensors generate have different characteristics, the output characteristic variation between the photosensors are corrected such that the output characteristics of all the photosensors agree with a reference output characteristic. A fixed pattern noise resulting from the pixel-to-pixel output characteristic variation can be suppressed.