Abstract: An in-vehicle network system deployed in a vehicle includes a plurality of first nodes configured to perform an operation relevant to a first function in the vehicle, a second node configured to perform an operation relevant to a second function different from the first function in the vehicle; and a relay device configured to relay communication between the first nodes and the second node. The relay device is configured to start relay of communication between the first nodes earlier than the relay of communication between the first node and the second node at a time of startup.

Abstract: It is an object of the present invention to provide a Japanese encephalitis preventive agent and a Japanese encephalitis vaccine agent, which are capable of imparting sufficient immunity to humans, even if these agents are used at a lower dose than the dose of a Japanese encephalitis vaccine for subcutaneous injection, or at a smaller number of administrations than the number of administrations of a Japanese encephalitis vaccine for subcutaneous injection. According to the present invention, provided is a Japanese encephalitis preventive agent, comprising a microneedle array having a sheet portion and a plurality of needle portions present on the upper surface of the sheet portion, wherein the aforementioned needle portions contain or carry an inactivated Japanese encephalitis virus.

Abstract: An object of the present invention is to provide a microneedle array which is capable of suppressing aggregation of liposomes in a case where a water-soluble polymer is mixed with liposomes during production of the microneedle array and is capable of localizing a drug at a tip of a needle. According to the present invention, provided is a microneedle array including: a sheet; and a plurality of needles which are present on an upper surface of the sheet, in which each needle contains a water-soluble polymer, a drug, a liposome, and a salt, a zeta potential of the liposome is ?10 mV or less, the zeta potential is a zeta potential of a liquid obtained by diluting the liposome to 0.1 mg/mL with 10 mmol/L of a phosphoric acid aqueous solution having a pH of 7, and a content of the salt in a portion of each needle which contains the liposome is 2.5 mmol/g or less.

Abstract: It is an object of the present invention to provide a Japanese encephalitis vaccine-containing microneedle array capable of suppressing a reduction in the activity of the Japanese encephalitis vaccine upon the production of the microneedle array. According to the present invention, provided is a microneedle array having a sheet portion and a plurality of needle portions present on the upper surface of the sheet portion, wherein the needle portion comprises at least one of an electrically neutral water-soluble polymer and a disaccharide, a Japanese encephalitis vaccine, and an electrically neutral surfactant, and the sheet portion comprises at least one of an electrically neutral water-soluble polymer and a disaccharide.

Abstract: An in-vehicle network system deployed in a vehicle includes a plurality of first nodes configured to perform an operation relevant to a first function in the vehicle, a second node configured to perform an operation relevant to a second function different from the first function in the vehicle; and a relay device configured to relay communication between the first nodes and the second node. The relay device is configured to start relay of communication between the first nodes earlier than the relay of communication between the first node and the second node at a time of startup.

Abstract: An in-vehicle network system deployed in a vehicle includes a plurality of first nodes configured to perform an operation relevant to a first function in the vehicle, a second node configured to perform an operation relevant to a second function different from the first function in the vehicle; and a relay device configured to relay communication between the first nodes and the second node. The relay device is configured to start relay of communication between the first nodes earlier than the relay of communication between the first node and the second node at a time of startup.

Abstract: An in-vehicle network system includes a plurality of relay devices that is connected to control devices of a vehicle, and communicates with each other and is configured such that each of a plurality of request devices that transmits a response request to the control device is connected to any one of the relay devices, a storage unit that stores a priority of the request devices, a master setter that sets, as the master, the relay device to which the request device having the highest priority has been connected among the relay devices to which any one of the request devices has been connected, and an arbitrator that performs arbitration to prioritize a response request from the request device having the highest priority when the response requests are transmitted from at least two of the request devices when the relay device in which the arbitrator is included is the master.

Abstract: An object of the present invention is to provide a method of producing a microneedle array that enables concentration of a drug at needle tips of the microneedle array. According to the present invention, provided is a method of producing a microneedle array, including a step of filling a hydrophobic mold with a drug-containing solution to form a needle tip, and a step of filling the mold including the formed needle tip with a liquid which contains a water-soluble polymer or disaccharides to form a needle base and a sheet, in which the drug-containing solution contains 0.01 mg/mL to 5 mg/mL of a surfactant.

Abstract: An in-vehicle network system includes a plurality of controllers; a plurality of communication lines connected to the controllers, respectively, a relay device connected to the controllers via the communication lines, and a retention determiner configured to determine whether retention of data occurs in the relay device. The relay device is configured to relay data between the communication lines, and configured to preferentially relay data having a priority equal to or higher than a predetermined priority such that the data reaches the controller that is a transmission destination among the controllers within a first predetermined time when the retention determiner determines that the retention occurs.

Abstract: An object of the present invention is to provide a microneedle array which is capable of suppressing aggregation of liposomes in a case where a water-soluble polymer is mixed with liposomes during production of the microneedle array and is capable of localizing a drug at a tip of a needle. According to the present invention, provided is a microneedle array including: a sheet; and a plurality of needles which are present on an upper surface of the sheet, in which each needle contains a water-soluble polymer, a drug, a liposome, and a salt, a zeta potential of the liposome is ?10 mV or less, the zeta potential is a zeta potential of a liquid obtained by diluting the liposome to 0.1 mg/mL with 10 mmol/L of a phosphoric acid aqueous solution having a pH of 7, and a content of the salt in a portion of each needle which contains the liposome is 2.5 mmol/g or less.

Abstract: Provided is a microneedle. The microneedle array includes a needle portion, which contains an inactivated whole virion influenza vaccine, and a sheet portion. Also provided is an administration method in which the microneedle array is administered and then administered secondly after an interval of equal to or greater than 24 hours and less than 2 months.

Abstract: An in-vehicle network system deployed in a vehicle includes a plurality of first nodes configured to perform an operation relevant to a first function in the vehicle, a second node configured to perform an operation relevant to a second function different from the first function in the vehicle; and a relay device configured to relay communication between the first nodes and the second node. The relay device is configured to start relay of communication between the first nodes earlier than the relay of communication between the first node and the second node at a time of startup.

Abstract: An in-vehicle network system includes a plurality of relay devices that is connected to control devices of a vehicle, and communicates with each other and is configured such that each of a plurality of request devices that transmits a response request to the control device is connected to any one of the relay devices, a storage unit that stores a priority of the request devices, a master setter that sets, as the master, the relay device to which the request device having the highest priority has been connected among the relay devices to which any one of the request devices has been connected, and an arbitrator that performs arbitration to prioritize a response request from the request device having the highest priority when the response requests are transmitted from at least two of the request devices when the relay device in which the arbitrator is included is the master.

Abstract: A system for treating a biogas stream is described. The system includes a venturi device in communication with a biogas stream source and an influent water source to combine the biogas stream and the influent water to produce a gas-water effluent. The system also includes a degas separator in communication with the venturi device for receipt of the gas-water effluent to produce a relatively low solubility gas effluent and a relatively high solubility gas-water mixture effluent. In addition, the system includes a gas-water pressure release valve in communication with the degas separator to control release of the relatively low solubility gas effluent and a discharge pressure control valve in communication with the degas separator to control release of the relatively high solubility gas-water mixture effluent.

Abstract: Provided is a microneedle. The microneedle array includes a needle portion, which contains an inactivated whole virion influenza vaccine, and a sheet portion. Also provided is an administration method in which the microneedle array is administered and then administered secondly after an interval of equal to or greater than 24 hours and less than 2 months.

Abstract: A system for treating a biogas stream is described. The system includes a venturi device in communication with a biogas stream source and an influent water source to combine the biogas stream and the influent water to produce a gas-water effluent. The system also includes a degas separator in communication with the venturi device for receipt of the gas-water effluent to produce a relatively low solubility gas effluent and a relatively high solubility gas-water mixture effluent. In addition, the system includes a gas-water pressure release valve in communication with the degas separator to control release of the relatively low solubility gas effluent and a discharge pressure control valve in communication with the degas separator to control release of the relatively high solubility gas-water mixture effluent.

Abstract: A system and method for removing unwanted elements from a gas stream. A biogas stream may be combined with a water stream influent in a venturi device to produce a gas-water mixture effluent. The gas-water mixture effluent is processed in a degas separator to separate and produce a relatively low solubility gas effluent and a relatively high solubility gas-water mixture effluent. The relatively high solubility gas-water mixture effluent is processed through a discharge pressure control valve based on a selected pressure to be maintained in said degas separator and then discharged or reused.

Abstract: A system and method for removing unwanted elements from a gas stream. A biogas stream may be combined with a water stream influent in a venturi device to produce a gas-water mixture effluent. The gas-water mixture effluent is processed in a degas separator to separate and produce a relatively low solubility gas effluent and a relatively high solubility gas-water mixture effluent. The relatively high solubility gas-water mixture effluent is processed through a discharge pressure control valve based on a selected pressure to be maintained in said degas separator and then discharged or reused.

Abstract: To satisfy a required processing speed and achieve the maximum power-saving effect in a microprocessor. A control value is calculated by performing proportional and integral processing on a deviation of a target instruction execution number from a measured instruction execution number. Unification processing or unification cancellation processing is performed in accordance with the control value. The unification processing stops supply of clocks to selected pipeline registers and controls the pipeline such that a signal passes through the pipeline registers so as to reduce the number of stages of the pipeline. The unification cancellation processing resumes the supply of clocks to the selected pipeline registers and controls the pipeline such that the pipeline registers latch the signal in synchronism with the clocks so as to increase the number of stages of the pipeline. The frequency of clocks supplied to the pipeline registers is changed in accordance with the changed number of stages.

Abstract: It is an object of the present invention to provide a structure comprised of a mixture of chitosan and collagen, which achieves both degradability and tissue adhesiveness. The present invention provides a structure comprised of a mixture of chitosan and collagen, wherein (i) the deacetylation degree of chitosan is 50% to 70%, (ii) the weight ratio of chitosan and collagen is 30/70 or more and less than 70/30.