Abstract: A target shell monitoring device 4 that monitors an attitude and a position of the target shell Tg1, a compression laser output device 5a that irradiates the target shell Tg1 with a compression laser light LS1, and a heating laser output device 6 that irradiates the target shell Tg1 with a heating laser light LS3 following the compression laser light LS1 are provided. The target shell Tg1 has a hollow spherical shell shape, includes an approximately spherical space Sp on an inner side thereof, includes at least one through hole H1 connecting an outer side thereof and the space Sp, and includes, on an outer surface Sf1 thereof, irradiation areas Ar1 and Ar2 to be irradiated with compression laser lights.

Abstract: A laser device 1 demultiplexes seed light L0 into a plurality of beams of laser light L1 and then continuously optically amplifies the plurality of beams of the laser light L1 with an amplifier 14. Therefore, its amplification factor can be set higher than that in the case of amplifying pulsed laser light. When producing multiplexed light L3 by multiplexing the beams of the amplified laser light L1 with a diffraction grating 16, respective phases of the beams of the laser light L1 are controlled such that an output peak of the multiplexed light L3 repeatedly appears at a converging position P1 at a predetermined time interval. This produces pulsed laser light at the converging position P1 from a plurality of beams of laser light L2 amplified at a high amplification factor. Hence, this laser device 1 can produce pulsed laser light with a high output.

Abstract: A laser device 1 demultiplexes seed light L0 into a plurality of beams of laser light L1 and then continuously optically amplifies the plurality of beams of the laser light L1 with an amplifier 14. Therefore, its amplification factor can be set higher than that in the case of amplifying pulsed laser light. When producing multiplexed light L3 by multiplexing the beams of the amplified laser light L1 with a diffraction grating 16, respective phases of the beams of the laser light L1 are controlled such that an output peak of the multiplexed light L3 repeatedly appears at a converging position P1 at a predetermined time interval. This produces pulsed laser light at the converging position P1 from a plurality of beams of laser light L2 amplified at a high amplification factor. Hence, this laser device 1 can produce pulsed laser light with a high output.

Abstract: A method of treating cancer, inflammatory disease, and autoimmune disease by administering to a subject in need thereof an effective amount of one or more 1,5-dipenylpenta-1,4-dien-3-one compounds. The compounds feature either or both of the phenyl rings being substituted with hydroxyl, diethyl(2-alkoxyethyl)amine, 1-(2-alkoxyethyl)piperidine, sulfonate, phosphinate, or phosphate.

Abstract: This invention relates to compounds of Formula (I), (II), or (III) as shown in the specification, which contain a 1,5-diphenylpenta-1,4-dien-3-one backbone. These compounds can be used to treat cancer, inflammatory disease, or autoimmune disease.

Abstract: A radiation generating apparatus comprises a fuel storage unit 20 for storing a mixed liquid 61, a pressure application unit 10 for applying a pressure to the mixed liquid 61, a jet formation unit 30 for forming a jet 61a of the mixed liquid 61, a reaction unit 44 for forming the jet 61a of the mixed liquid 61 therein, a pressure adjustment unit 41 for setting a pressure in the reaction unit 44 lower than an internal pressure of the jet formation unit 30, and a light source unit 45 for irradiating a particle group 63a with laser light L1.

Abstract: A laser device including a plurality of oscillating means for oscillating a plurality of laser lights being continuous lights and having frequencies different from each other, respectively, multiplexing means for multiplexing, after amplifying or without amplifying, the respective laser lights oscillated from the respective oscillating means at a predetermined position to generate a multiplexed light, and phase control means for controlling the phase of each of the laser lights so that a peak in output of the multiplexed light repeatedly appears at predetermined time intervals at the predetermined position (so that the same pulse temporal waveform repeatedly appears at predetermined time intervals).

Abstract: A check valve in the three-way stopcock unit includes: a first housing having a valve seat in which an opening is provided; a second housing inserted into the first housing; and a valve element held between the valve seat of the first housing and an opening end portion of the second housing. The valve element has a substantially U-shaped cut line formed outside of an outer rim portion of the opening provided in the valve seat of the first housing, and inside of an inner rim portion of the second housing. A portion inside of the cut line is used as a switching valve, and the valve seat of the first housing and the opening end portion of the second housing are closed in a liquid-tight state at a portion outside of the cut line.

Abstract: An object is to be capable of inducing a nuclear fusion reaction at a relatively high efficiency and downsize a device. A nuclear fusion device 1 of the present invention includes a nuclear fusion target 7 including a target substrate 7a containing deuterium or tritium and a thin-film layer 7b containing deuterium or tritium stacked on the target substrate 7a, a vacuum container 5 for storing the nuclear fusion target 7, and a laser unit 3 for irradiating two successive first and second pulsed laser lights P1, P2 toward the thin-film layer 7b of the nuclear fusion target 7, and the intensity of the first pulsed laser light P1 is set to a value that is smaller than that of the second pulsed laser light P2 and allows peeling of the thin-film layer 7b from the target substrate 7a.

Abstract: An object of the present invention is to efficiently improve uniformity of energy lines to be irradiated.

Abstract: This invention relates to compounds of Formula (I), (II), or (III) as shown in the specification, which contain a 1,5-diphenylpenta-1,4-dien-3-one backbone. These compounds can be used to treat cancer, inflammatory disease, or autoimmune disease.

Abstract: A solid-state laser apparatus 1 bounces laser light L2 between an end mirror 3 and an output mirror 4 via a slab-type solid-state laser medium 2 excited by excitation light L1 to thereby amplify and output the laser light L2. The solid-state laser medium 2 includes incident/exit end faces 2a, 2b on and from which the laser light L2 is made incident and exits, and reflecting end faces 2c, 2d which reflect the laser light L2 so that the incident laser light L2 propagates in a zigzag manner. The incident/exit end face 2a is made incident with the excitation light L1 so that the excitation light L1 propagates along substantially the same propagation path as that of the laser light L2 within the solid-state laser medium 2. Accordingly, a solid-state laser apparatus which can improve the coupling efficiency between the excitation light and the laser light is realized.

Abstract: An illumination device includes: a light emitting element to be a light source; a light amount detecting means for detecting the amount of light emitted by the light emitting element; a light emitting element drive means for controlling drive current supplied to the light emitting element so that the difference between the light mount detected by the light amount detecting means and a light amount target value becomes small; a junction temperature detecting means for calculating junction temperature of the light emitting element; and a setting means for setting the light amount target value in accordance with the junction temperature detected by the junction temperature detecting means.

Abstract: A method and apparatus for optimizing picture quality of a video signal. The method includes displaying a user menu having a plurality of choices of video labels; receiving a choice of video label from the plurality via an input from a user; translating the video label into a label code; receiving at least a first video processing parameter from a look-up table corresponding to the label code; and configuring a video processor according to the first video processing parameter.

Abstract: The present invention relates to a solid-state laser module, and so on, having a structure for enabling optical output of high quality to be obtained. The solid-state laser module includes a vacuum container with windows, and a heat sink, a solid-state laser medium, and a pair of transparent members are housed in the vacuum container in an integrally assembled state. The solid-state laser medium and the pair of transparent members respectively have disk shapes, and the pair of transparent members sandwich the solid-state laser medium. The thermal conductivity of each of the pair of transparent members is higher than the thermal conductivity of the solid-state laser medium.

Abstract: The present invention provides methods for screening compounds which inhibit activation of a member of the IL-6 signaling pathways, comprising: (a) a positive screening step using a cell capable of being killed by IL-6 stimulation to select compounds which inhibit death of the cell when it is stimulated by IL-6; and then (b) a biochemical screening step to further select compounds which inhibit activation of a member of the IL-6 signaling pathways by a biochemical means from the compounds selected in step (a). The present invention also provides compounds which inhibit activation of a member of the IL-6 signaling pathways identified using said methods.

Abstract: The present invention relates to an optical mask at low cost and so on having a structure capable of reducing further a peak of beam intensity caused by diffraction. The optical mask is constructed by overlapping a first mask and a second mask. The first mask and second mask each are a serrated aperture mask. The schematic shapes of the respective apertures of the first mask and second mask are almost rectangular and identical to each other. The fringe defining the aperture of the first mask is machined in a serrated shape, and the fringe defining the aperture of the second mask also is machined in a serrated shape. In the optical mask, the first mask and second mask are overlapped so that the serrations of the fringes defining the respective apertures of the first mask and second mask are located alternately.

Abstract: An illumination device includes: a light emitting element to be a light source; a light amount detecting means for detecting the amount of light emitted by the light emitting element; a light emitting element drive means for controlling drive current supplied to the light emitting element so that the difference between the light mount detected by the light amount detecting means and a light amount target value becomes small; a junction temperature detecting means for calculating junction temperature of the light emitting element; and a setting means for setting the light amount target value in accordance with the junction temperature detected by the junction temperature detecting means.

Abstract: A solid-state laser apparatus which can improve its durability is provide. In the solid-state laser apparatus 1, a main pipe 11 for circulating a coolant through a solid-state laser medium 3 is provided with a heat exchanger 14, whereby the laser medium 3 is prevented from raising its temperature. When the coolant becomes acidic or alkaline, a controller 24 controls a flow regulating valve 23, so as to increase the flow rate of the coolant flowing into a bypass pipe 21 provided with a deionizing filter 22, whereby the acidity or alkalinity of the coolant can be weakened. This can prevent the coolant from deteriorating a predetermined part of the laser apparatus 3, and thus can improve the durability of the solid-state laser apparatus 1.

Abstract: A solid laser module etc. having a structure that enables to obtain a high-quality light output. The solid laser module has a vacuum container with a window, and a heat sink, a solid laser medium, and a pair of transparent members are received in an integrally assembled state in the container. The solid laser medium and the pair of transparent members are each formed in a disc shape, and the solid laser medium is sandwiched between the pair of transparent members. The thermal conductivity of each of the pair of transparent members is higher than the thermal conductivity of the solid laser medium. The heat sink is shaped to simultaneously hold portions of the pair of transparent members that hold the solid laser medium in between. A heat insulation region having a lower thermal conductivity than the solid laser medium is provided between the heat sink and the solid laser medium.