Abstract: The present invention provides materials and methods for modulating FATP expression and/or activity in vivo. The materials and methods have numerous diagnostic, prophylactic, and therapeutic applications for various diseases and conditions that are influenced by FATPs, or characterized by excessive or inadequate FATP expression or activity.

Abstract: A user interface of a wireless user terminal provides a forecast of a future rate discount that may apply at a future time and/or at a possible future location of the wireless user terminal. The forecast may be displayed as a map and/or as textual or graphical information, and may be provided in response to a user request, in response to receipt of a message from the wireless network and/or automatically at a given time. Related systems, methods and devices are described.

Abstract: Methods and compositions for modulating blood-neural barrier (BNB) for the treatment of CNS conditions such as edema, and for increased drug delivery efficacy across the BNB. The present invention further relates to improved tPA treatment of ischemic cerebrovascular and related diseases in combination with antagonism of the PDGF signaling pathway. The inventive method and composition is particularly suitable for conjunctive therapy of ischemic stroke using tPA and an anti-PDGF-C antagonist or an anti-PDGFR-? antagonist.

Abstract: A telescopic shaft for vehicles comprising an inner shaft axially movable in an outer shaft. The telescopic shaft comprises at least two rows of balls with at least one ball per row between the inner shaft and the outer shaft. A row of balls is arranged on at least one ball race arranged against the inner shaft. The ball race is wedge shaped on its against the inner shaft facing surface. The telescopic shaft comprises a prestress mechanism which pushes the ball race along a wedge unit axially in relation to and radially in the direction against the outer shaft. whereby the telescopic shaft is prestressed. The prestress mechanism is arranged to release the prestress when the alteration in length of the telescopic shaft exceeds a predetermined length.

Abstract: The present invention provides materials and methods for modulating FATP expression and/or activity in vivo. The materials and methods have numerous diagnostic, prophylactic, and therapeutic applications for various diseases and conditions that are influenced by FATPs, or characterized by excessive or inadequate FATP expression or activity.

Abstract: Methods and compositions for modulating blood-neural barrier (BNB) for the treatment of CNS conditions such as edema, and for increased drug delivery efficacy across the BNB. The present invention further relates to improved tPA treatment of ischemic cerebrovascular and related diseases in combination with antagonism of the PDGF signaling pathway. The inventive method and composition is particularly suitable for conjunctive therapy of ischemic stroke using tPA and an anti-PDGF-C antagonist or an anti-PDGFR-? antagonist.

Abstract: The present invention is directed to methods and compositions for making and using chimeric polypeptides that comprise a VEGFR-2 ligand. The chimeric molecules of the present invention retain VEGFR-2 binding activity and an enhanced angiogenic activity as compared to native VEGF-A.

Abstract: A steering wheel arrangement for a motor vehicle includes a steering column having a first end for cooperation with a steering wheel and a second end for cooperation with a vehicle steering mechanism. The steering wheel arrangement further includes a suspension arrangement for the steering column. The suspension arrangement includes two pivot joints and is pivotally connected to the steering column via a third pivot joint, the first, second and third pivot joints including first, second and third locking arrangements, respectively. The steering wheel arrangement has thus three adjustable pivot points where only one or two of the three pivot joints are adjustable in a first step depressing a foot pedal to a first position and only the remaining of the three pivot joints are adjustable in a second step depressing the foot pedal to a second position which implies that the adjustments can be made in a secure way by the driver during the ride.

Abstract: The present invention provides materials and methods for modulating FATP expression and/or activity in vivo. The materials and methods have numerous diagnostic, prophylactic, and therapeutic applications for various diseases and conditions that are influenced by FATPs, or characterized by excessive or inadequate FATP expression or activity.

Abstract: The present invention is directed to methods and compositions for making and using chimeric polypeptides that comprise a VEGFR-2 ligand. The chimeric molecules of the present invention retain VEGFR-2 binding activity and an enhanced angiogenic activity as compared to native VEGF-A.

Abstract: The present invention relates to a method of using a cleaning device for cleaning outlet ports (11) or the like and/or outlet spouts (12) or the like in soda recovery boilers (13) or the like, the cleaning device comprising at least one connecting rod (9). The cleaning device has at least one front tool part (1a-d, 3, 6), mounted on said connecting rod (9).

Abstract: A cleaning device, cleaning tool and method for cleaning outlet ports or the like and/or outlet spouts (12) or the like in soda recovery boilers of the like the cleaning device including at least one connecting rod and at least one front tool part mounted on the connecting rod.

Abstract: The present invention provides materials and methods for modulating FATP expression and/or activity in vivo. The materials and methods have numerous diagnostic, prophylactic, and therapeutic applications for various diseases and conditions that are influenced by FATPs, or characterized by excessive or inadequate FATP expression or activity.

Abstract: The invention relates to a steering wheel adjusting mechanism (2) for motor vehicles (4) comprising a pivotally to the vehicle (4) attached supporting arm (8), and a pivotally to the supporting arm (8) attached steering shaft housing unit (12), where at least one locking plate package (14 and 16, respectively) is attached to both the vehicle (4) and the steering shaft housing unit (12), which locking plate package (14 and 16, respectively) is compressible with clamping means (18) in order to lock the steering shaft housing unit (12) relative to the vehicle (4). Optionally, the supporting arm (8) is pivotally attached to a to the vehicle (4) mountable fastening part (20). Optionally, the locking plate package (14 and 16, respectively) is attached to a firmly to the vehicle (4) mountable fastening unit (22). Optionally, the fastening part (20) and the fastening unit (22) are integrated with each other to a firmly to the vehicle (4) mountable steering wheel adjusting bracket (24).

Abstract: Methods for inhibiting angiogenesis comprising administering tissue-plasminogen activator (tPA) inhibitors, and pharmaceutical compositions suitable for the methods comprising the tPA inhibitors. Also provided are methods for stimulating angiogenesis comprising administering tPA to a patient in need thereof, and pharmaceutical compositions comprising an effective amount of tPA for the methods of stimulation. The present invention discloses that tPA is a specific PDGF-C activating protease, and that the CUB-domains in PDGF-CC directly interact with the protease, are required for efficient proteolysis, and released CUB-domains are tPA inhibitors. Preferably, the method and compositions of the present invention are used for simultaneously stimulating, or simultaneously inhibiting, thrombolysis and angiogenesis.

Abstract: The invention relates to a telescopic shaft for vehicles comprising an inner shaft (14) axially movable in an outer shaft (16), where the telescopic shaft (4) comprises at least two rows (35, 37) of balls (36, 38) with at least one ball (36, 38) a row (35, 37) between the inner shaft (14) and the outer shaft (16), where a row (35) of balls (36) is arranged on at least one ball race (40) arranged against the inner shaft (14), where the ball race (40) is wedge shaped on its against the inner shaft (14) facing surface and that the telescopic shaft (4) comprises a prestress mechanism (46) which pushes the ball race (40) along a wedge unit (48) axially in relation to and radially in the direction against the outer shaft (16) whereby the telescopic shaft (48) is prestressed and that the prestress mechanism (46) is arranged to release the prestress when the alteration in length of the telescopic shaft (4) exceeds a predetermined length.

Abstract: VEGF-B is shown to be needed for cardiac muscle revascularization after heart infarction, and methods of promoting or stimulating vascular development, e.g. angiogenesis and/or arteriogenesis, particularly in ischemic mammals, are disclosed.

Abstract: The present invention provides materials and methods for modulating FATP expression and/or activity in vivo. The materials and methods have numerous diagnostic, prophylactic, and therapeutic applications for various diseases and conditions that are influenced by FATPs, or characterized by excessive or inadequate FATP expression or activity.

Abstract: A method of modulating, regulating and/or stabilizing angiogenesis in a mammal in need thereof, in which the PDGF-D level or activity or both in the mammal are modulated or increased. In preferred embodiments, an active PDGF-D polypeptide, or a polynucleotide encoding an active PDGF-D is administered to the mammal, preferably at a location where angiogenesis modulation or stabilization is desired. The PDGF-D is advantageously co-administered with an angiogenic growth factor, such as a member of the VEGF family of growth factors, in particular VEGF-E. The claimed method inhibits leakage of blood vessels and is useful, inter alia, for treatment of edemas.

Abstract: A steering wheel arrangement for a motor vehicle includes a steering column having a first end for cooperation with a steering wheel and a second end for cooperation with a vehicle steering mechanism. The steering wheel arrangement further includes a suspension arrangement for the steering column. The suspension arrangement includes two pivot joints and is pivotally connected to the steering column via a third pivot joint, the first, second and third pivot joints including first, second and third locking arrangements, respectively. The steering wheel arrangement has thus three adjustable pivot points where only one or two of the three pivot joints are adjustable in a first step depressing a foot pedal to a first position and only the remaining of the three pivot joints are adjustable in a second step depressing the foot pedal to a second position which implies that the adjustments can be made in a secure way by the driver during the ride.