Abstract: Heterocyclic compounds as Wee1 inhibitors are provided. The compounds may find use as therapeutic agents for the treatment of diseases and may find particular use in oncology.

Abstract: An agent in a multi-agent system is provided with a policy model that controls communication of the agent with other agents in the multi-agent system. The policy model is trained by using MARL. The policy model receives more messages from one or more other agents in the multi-agent system. The policy model generates a reward score based at least on a hidden state of the agent and the one or more messages. The reward score represents an aggregation of a value of sending the message for a task and a cost of sending the message. The policy model determines whether to send the message based on the reward score. After determining to send the message, the policy model generates the message based on the hidden state of the agent and the one or more messages and sends the message to one or more other agents in the multi-agent system.

Abstract: Heterocyclic compounds as Weel inhibitors are provided. The compounds may find use as therapeutic agents for the treatment of diseases and may find particular use in oncology.

Abstract: Heterocyclic compounds as Wee1 inhibitors are provided. The compounds may find use as therapeutic agents for the treatment of diseases and may find particular use in oncology.

Abstract: Heterocyclic compounds as Wee1 inhibitors are provided. The compounds may find use as therapeutic agents for the treatment of diseases and may find particular use in oncology.

Abstract: The present disclosure relates to a process for producing homogeneous solutions comprising dissolved polyacrylonitrile-based polymer, and a system suitable therefor. The homogeneous polymer solutions produced by the process described herein may be used for producing carbon fiber, typically carbon fiber used in manufacturing composite materials.

Abstract: This invention provides for substituted pyrazolo[3,4-d]pyrimidine compounds of the Formula (I): as Wee1 inhibitors. The substituted pyrazolo[3,4-d]pyrimidine compounds may find use as therapeutic agents for the treatment of diseases. The substituted pyrazolo[3,4-d]pyrimidine compounds may also find particular use in oncology.

Abstract: Heterocyclic compounds as Wee1 inhibitors are provided. The compounds may find use as therapeutic agents for the treatment of diseases and may find particular use in oncology.

Abstract: Methods and systems are presented for creating and distributing blockchain-backed redistributable electronic content components. These techniques provider greater computer security and authentication controls, in various embodiments. An electronic content component associated with a first entity and a first set of actions is created. The electronic content component is published, and the first set of actions and a block representing the electronic content component are added to a blockchain. A second entity requests use of the electronic content component and a distribution agreement between the first and second entities associated with a second set of actions is created. The second set of actions and a block representing the distribution agreement are added to a blockchain. The electronic content component and distribution agreement are validated based on the blockchain, and custom content including the electronic content component is published.

Abstract: Techniques are provided for monocular 3D object detection from an image semantics network. An image semantics network (ISN) is a single stage, single image object detection network that is based on single shot detection (SSD). In an embodiment, the ISN augments the SSD outputs to provide encoded 3D properties of the object along with a 2D bounding box and classification scores. For each priorbox, a 3D bounding box is generated for the object using the dimensions and location of the priorbox, the encoded 3D properties and camera intrinsic parameters.

Abstract: A system comprises an engine mounted to an aircraft wing by a plurality of clevis pins, a respective strain sensor mounted in at least one of the clevis pins, and a monitoring system operatively connected to each respective strain sensor to monitor stress in each of the clevis pins having a respective strain sensor.

Abstract: The present disclosure relates to the production of polyacrylonitrile-based polymers with high conversion by a process comprising reacting acrylonitrile with at least one comonomer in the presence of a radical initiator in a liquid medium, wherein the radical initiator is present in an amount of from about 0.6 wt % to about 1.8 wt %, relative to the amount of acrylonitrile, and wherein no chain transfer agent is present. The polyacrylonitrile-based polymers produced may be used for producing carbon fiber, typically carbon fiber used in manufacturing composite materials.

Abstract: The present disclosure relates to the control of the degree of swelling of polymer fiber, such as polymer fiber used in the manufacturing of composite materials, by control of the pH of the coagulation bath during spinning.

Abstract: A computer-implemented method of managing an inventory of articles includes receiving, by a transfer processor, article information associated with the articles, and identifying, by the transfer processor, one of the articles based on an article identifier. The method also includes retrieving article information based on the identifier, the article information including care information for the one of the articles, and, when the identified article is an article requiring special care, a special care requirement is included in the care information, and preparing the article for transfer based on the care information.

Abstract: A computer-implemented method of managing an inventory of articles includes receiving, by a transfer processor, article information associated with the articles, and identifying, by the transfer processor, one of the articles based on an article identifier. The method also includes retrieving article information based on the identifier, the article information including care information for the one of the articles, and, when the identified article is an article requiring special care, a special care requirement is included in the care information, and preparing the article for transfer based on the care information.

Abstract: Various embodiments described herein relate to an intelligent warning system in a communication service. One embodiment of the present invention analyzes a user's biometric signals and image data of one of the users in a communication session to determine a distress level. In addition, location data indicating the user's velocity and direction can be used to determine a distress level. If the biometric signals or the image data indicate a distress level that meets or exceeds a threshold level, a notification is automatically sent to a remote user. This can allow a remote user to render assistance to a user in distress, even when the user is unable to communicate one or more conditions.

Abstract: The present invention relates to a non return valve, having a supporting structure in cap part (upper body portion) such as but not limited to a wall or any extrusion for better and improved self assembly and eliminates the leakage of the non return valve due to weld flash at sealing surface. In addition, a filter unit, which is either inbuilt or insert molded that can be assembled within the closed state of fully assembled non return valve unit. The present invention also relates to non return valve includes a cap (upper body portion), a filter, a diaphragm, a base for diaphragm, a compression spring, and a bottom body (lower body portion).

Abstract: Various embodiments described herein relate to an intelligent warning system in a communication service. One embodiment of the present invention analyzes a user's biometric signals and image data of one of the user's in a communication session to determine a distress level. In addition, location data indicating the user's velocity and direction can be used to determine a distress level. If the biometric signals or the image data indicate a distress level that meets or exceeds a threshold level, a notification is automatically sent to a remote user. This can allow a remote user to render assistance to a user in distress, even when the user is unable to communicate one or more conditions.

Abstract: A data processing device is described including one or more processors implementing a plurality of data processing entities, one or more software interrupt nodes and an access register for each software interrupt node. The access register specifies which one or more data processing entities of the plurality of data processing entities is/are each allowed to, as interrupt source data processing entity, trigger an interrupt service request on the software interrupt node for another one of the plurality of data processing entities as an interrupt target processing entity. Each software interrupt node is configured to forward an interrupt service request triggered by an interrupt source data processing entity which is allowed to trigger an interrupt service request on the software interrupt node to an interrupt target processing entity.

Abstract: A game cloud server, a method of operating a cloud server, and a method of playing a game on a game cloud server are disclosed. In one example, the game cloud server includes: (1) one or more processing units that virtually supports different gaming applications according to a gaming operating mode, and (2) an operating mode selector that is coupled to the one or more processing units and has (2A) a virtual fusing register that selects the gaming operating mode for executing the different virtually supported gaming applications, and (2B) a security processor that enables a secure virtual fusing based on documented security files authorizing selection of the gaming operating mode, separately from executing an operating system of the one or more processing units, wherein the gaming operating mode is a reconfigurable operating mode selectable from at least one signed license file of the documented security files.